Plasma hypoxanthine levels in ARDS: Implications for oxidative stress, morbidity, and mortality

American Journal of Respiratory and Critical Care Medicine

Volumn 155, Issue 2, 1997, Pages 479-484

  Quinlan, Gregory J ^a   Lamb, Nicholas J ^a   Tilley, Rosalind ^a   Evans, Timothy W ^a   Gutteridge, John M C ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; HYPOXANTHINE; REACTIVE OXYGEN METABOLITE; XANTHINE;

ADOLESCENT; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL ARTICLE; DISEASE ASSOCIATION; FEMALE; HUMAN; HYPOXIA; LUNG RESECTION; MALE; MORBIDITY; MORTALITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROGNOSIS; SCHOOL CHILD; SURVIVAL RATE;

EID: 0031059884     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.155.2.9032182     Document Type: Article

References (29)

1. Bernard, G., A. Artigas, K. Brigham, J. Carlet, K. Falke, L. Hudson, M. Lamy, J. R. Legall, A. Morris, and R. Spragg. 1994. The American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial co-ordination. Am. J. Respir. Crit. Care Med. 149:818-824.
2. Williams, E. A, T. W. Evans, and P. Goldstraw. 1996. Acute lung injury following lung resection: is one lung anaesthesia to blame? Thorax 51:114-117.
3. Hayes, J. P., E. A. Williams, P. Goldstraw, and T. W. Evans. 1995. Lung injury in patients following thoracotomy. Thorax 50:990-992.
4. Quinlan, G. J., T. W. Evans, and J. M. C. Gutteridge. 1994. Oxidative damage to plasma proteins in the adult respiratory distress syndrome. Free Rad. Res. 20:289-298.
5. Gutteridge, J. M. C., G. J. Quinlan, S. Mumby, A. Heath, and T. W. Evans. 1994. Primary plasma antioxidants in adult respiratory distress syndrome patients: changes in iron-oxidizing, iron-binding and free radical-scavenging proteins. J. Lab. Clin. Med. 124:263-273.
6. McCord, J. M. 1985. Oxygen-derived free radicals in postischemic tissue injury. N. Engl. J. Med. 312:159-163.
7. Parks, D. A. and N. D. Granger. 1986. Xanthine oxidase: biochemistry, distribution and physiology. Acta Physiol. Scand. 548:87-99.
8. Grum, C. M., R. A. Ragsdale, L. H. Ketai, and R. H. Simon. 1987. Plasma xanthine oxidase activity in patients with adult respiratory distress syndrome. J. Crit. Care 2:22-26.
9. Xia, Y., and J. L. Zweier. 1995. Substrate control of free radical generation from xanthine oxidase in the postischemic heart. J. Biol. Chem. 270:18797-18803.
10. Wiezorek, J. S., D. H. Brown, D. E. Kupperman, and C. A. Brass. 1994. Rapid conversion to high xanthine oxidase activity in viable Kupffer cells during hypoxia. J. Clin. Invest. 94:2224-2230.
11. Grum, C. M., R. H. Simon, D. R. Danzker, and I. H. Fox. 1985. Evidence for adenosine triphosphate degradation in critically ill patients. Chest 88:763-767.
12. Saugstad, O. D., and T. Ostrem. 1977. Hypoxanthine and urate levels of plasma during and after hemorrhagic hypotension in dogs. Eur. Surg. Res. 9:48-56.
13. Russell, G. A. B., G. Jeffers, and R. W. I. Cooke. 1992. Plasma hypoxanthine: a marker for hypoxic-ischaemic induced periventricular leucomalacia? Arch. Dis. Child. 67:388-392.
14. Murray, M., M. Mathay, J. Luce, and M. Flick. 1988. An expanded definition of the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 138:720-723.
15. Kock, R., B. Delvoux, and H. Greiling. 1993. A high-performance liquid chromatic method for the determination of hypoxanthine, xanthine, uric acid and allantoin in serum. Eur. J. Clin. Chem. Clin. Biochem. 31:303-310.
16. Limper, A. H., U. Specks, M. W. Brutinel, W. J. Martin, and M. S. Rohrbach. 1993. Interlobar variation in the recovery of bronchoalveolar lavage fluid, cell populations, and angiotensin-converting enzyme in normal volunteers. J. Lab. Clin. Med. 121:785-791.
17. Fridovich, I. 1985. Cytochrome c. In R. A. Greenwald, editor. Handbook of Methods for Oxygen Radical Research. CRC Press, Boca Raton, FL. 213-215.
18. Quinlan, G. J., N. J. Lamb, T. W. Evans, and J. M. C. Gutteridge. 1996. Plasma fatty acid changes and increased lipid peroxidation in patients with adult respiratory distress syndrome. Crit. Care Med. 24:241-246.
19. Gutteridge, J. M. C., S. Mumby, G. J. Quinlan, K. F. Chung, and T. W. Evans. 1996. Pro-oxidant iron is present in human pulmonary epithelial lining: implications for oxidative stress in the lung. Biochem. Biophys. Res. Commun. 220:1024-1027.
20. Phan, S., D. Gannon, J. Varani, U. Ryan, and P. Ward. 1989. Xanthine oxidase activity in rat pulmonary artery endothelial cells and its alteration by activated neutrophils. Am. J. Pathol. 134:1201-1211.
21. Till, G., H. Friedl, and P. Ward. 1991. Lung injury and complement activation: role of neutrophils and xanthine oxidase. Free Rad. Biol. Med. 10:379-386.
22. Terada, L., J. Dormish, P. Shanley, J. Leff, B. Anderson, and J. Repine. 1992. Circulating xanthine oxidase mediates lung neutrophil sequestration after intestinal ischemia-reperfusion. Am. J. Physiol. 263: L294-L401.
23. Moores, H. K., C. J. Beehler, M. E. Hanley, P. F. Shanley, E. E. Stevens, J. E. Repine, and L. S. Terada. 1994. Xanthine oxidase promotes neutrophil sequestration but not injury in hyperoxic lungs. J. Appl. Physiol. 76:941-945.
24. Tate, R., K. Vanbenthuysen, D. Shasby, I. F. McMurty, and J. E. Repine. 1982. Oxygen radical mediated permeability oedema and vasoconstriction in isolated perfused rabbit lungs. Am. Rev. Respir. Dis. 126:802-806.
25. Ward, P. 1991. Mechanisms of endothelial cell injury. J. Lab. Clin. Med. 118:421-426.
26. Kurosaki, M., L. Calzi, M. Scanziani, E. Garattini, and M. Terao. 1995. Tissue- and cell-specific expression of mouse xanthine oxoreductase gene in vivo: regulation by bacterial LPS. Biochem. J. 306:225-234.
27. Schwartz, M., J. Repine, and E. Abraham. 1995. Xanthine oxidase-derived oxygen radicals increase lung cytokine expression in mice subjected to hemorrhagic shock. Am. J. Respir. Cell Mol. Biol. 12: 434-440.
28. Tan, S., Y. Yokoyama, E. Dickens, T. G. Cash, B. A. Freeman, and D. A. Parks. 1993. Xanthine oxidase activity in the circulation of rats following hemorrhagic shock. Free Rad. Biol. Med. 15:407-414.
29. Adachi, T., T. Fukushima, Y. Usami, and K. Hirano. 1993. Binding of human xanthine oxidase to sulphated glycosaminoglycans on the endothetial-cell surface. Biochem. J. 289:523-527.