Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing

Nucleic Acids Research

Volumn 43, Issue 19, 2015, Pages 9379-9392

  Pinder, Jordan ^a   Salsman, Jayme ^a   Dellaire, Graham ^a,b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b Beatrice Hunter Cancer Research Institute   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; PROTEIN VARIANT; 3-((BENZYLAMINO)SULFONYL)-4-BROMO-N-(4-BROMOPHENYL)BENZAMIDE; 5,6-BIS(BENZYLIDENEAMINO)-2-MERCAPTOPYRIMIDIN-4-OL; BENZAMIDE DERIVATIVE; BRCA1 PROTEIN; DEOXYRIBONUCLEASE; NUCLEAR PROTEIN; OLIGONUCLEOTIDE; PYRIMIDINE DERIVATIVE; RAD51 PROTEIN; RNA; SCHIFF BASE; SULFONAMIDE;

ARTICLE; CELL NUCLEUS; CELL NUCLEUS INCLUSION BODY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA MODIFICATION; DNA REPAIR; ENHANCER REGION; EXON; GENE INSERTION; GENE LOCUS; GENE TARGETING; GENETIC SCREENING; GENETIC TRANSFECTION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; HUMAN GENOME; LEUKEMIA CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN DOMAIN; U2OS CELL LINE; CRISPR CAS SYSTEM; DOUBLE STRANDED DNA BREAK; FLOW CYTOMETRY; GENETICS; GENOME; HEK293 CELL LINE; METABOLISM; PROCEDURES; RECOMBINATION REPAIR; TUMOR CELL LINE;

BENZAMIDES; BRCA1 PROTEIN; CELL LINE, TUMOR; CRISPR-CAS SYSTEMS; DNA BREAKS, DOUBLE-STRANDED; ENDODEOXYRIBONUCLEASES; FLOW CYTOMETRY; GENE KNOCK-IN TECHNIQUES; GENOME; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; NUCLEAR PROTEINS; OLIGONUCLEOTIDES; PYRIMIDINES; RAD51 RECOMBINASE; RECOMBINATIONAL DNA REPAIR; RNA; SCHIFF BASES; SULFONAMIDES;

EID: 84950273964     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv993     Document Type: Article

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