Leukotriene C 4 is the major trigger of stress-induced oxidative DNA damage

Nature Communications

Volumn 6, Issue , 2015, Pages

  Dvash, Efrat ^a   Har Tal, Michal ^a   Barak, Sara ^a   Meir, Ofir ^a,b   Rubinstein, Menachem ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b Monsanto   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CASPASE 3; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; FLUOROURACIL; GLUTATHIONE TRANSFERASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; LEUKOTRIENE C4; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; VINCRISTINE; BREFELDIN A; LEUKOTRIENE-C4 SYNTHASE; MGST2 PROTEIN, MOUSE; TUNICAMYCIN;

DNA; ENZYME ACTIVITY; INHIBITOR; METABOLITE; PATHOLOGY; TRANSLOCATION;

ARTICLE; ASTHMA; CELL DEATH; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ANIMAL; CELL CULTURE; CELL SURVIVAL; CHEMICALLY INDUCED; DRUG EFFECTS; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GENETICS; KIDNEY DISEASE; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; RNA INTERFERENCE;

ANIMALS; BREFELDIN A; CELL SURVIVAL; CELLS, CULTURED; DNA DAMAGE; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HUMANS; KIDNEY DISEASES; LEUKOTRIENE C4; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS; RNA INTERFERENCE; TUNICAMYCIN;

EID: 84949870760     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10112     Document Type: Article

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