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Volumn 18, Issue 12, 2013, Pages 1418-1427

Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; APOCYNIN; ENZYME INHIBITOR; FIBRINOLYTIC AGENT; GKT 136901; HYDROGEN PEROXIDE; PEPTIDE DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; UNCLASSIFIED DRUG; VAS 2870; VAS 3947;

EID: 84875181886     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2012.4797     Document Type: Review
Times cited : (125)

References (72)
  • 4
    • 46249086250 scopus 로고    scopus 로고
    • Nox4 and nox2 NADPH oxidases mediate distinct cellular redox signaling responses to agonist stimulation
    • Anilkumar N, Weber R, Zhang M, Brewer A, and Shah AM. Nox4 and nox2 NADPH oxidases mediate distinct cellular redox signaling responses to agonist stimulation. Arterioscler Thromb Vasc Biol 28: 1347-1354, 2008..
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1347-1354
    • Anilkumar, N.1    Weber, R.2    Zhang, M.3    Brewer, A.4    Shah, A.M.5
  • 6
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROSgenerating NADPH oxidases: Physiology and pathophysiology
    • Bedard K and Krause KH. The NOX family of ROSgenerating NADPH oxidases: physiology and pathophysiology. Physiol Rev 87: 245-313, 2007..
    • (2007) Physiol Rev , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 7
    • 77955716367 scopus 로고    scopus 로고
    • Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury
    • Ben Mkaddem S, Pedruzzi E, Werts C, Coant N, Bens M, Cluzeaud F, Goujon JM, Ogier-Denis E, and Vandewalle A. Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury. Cell Death Differ 17: 1474-1485, 2010..
    • (2010) Cell Death Differ , vol.17 , pp. 1474-1485
    • Ben Mkaddem, S.1    Pedruzzi, E.2    Werts, C.3    Coant, N.4    Bens, M.5    Cluzeaud, F.6    Goujon, J.M.7    Ogier-Denis, E.8    Vandewalle, A.9
  • 10
    • 0029888311 scopus 로고    scopus 로고
    • Role of oxidants in ischemic brain damage
    • Chan PH. Role of oxidants in ischemic brain damage. Stroke 27: 1124-1129, 1996..
    • (1996) Stroke , vol.27 , pp. 1124-1129
    • Chan, P.H.1
  • 11
    • 0035149749 scopus 로고    scopus 로고
    • Reactive oxygen radicals in signaling and damage in the ischemic brain
    • Chan PH. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 21: 2-14, 2001..
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 2-14
    • Chan, P.H.1
  • 12
    • 79954628624 scopus 로고    scopus 로고
    • NADPH oxidase is involved in post-ischemic brain inflammation
    • Chen H, Kim GS, Okami N, Narasimhan P, and Chan PH. NADPH oxidase is involved in post-ischemic brain inflammation. Neurobiol Dis 42: 341-348, 2011..
    • (2011) Neurobiol Dis , vol.42 , pp. 341-348
    • Chen, H.1    Kim, G.S.2    Okami, N.3    Narasimhan, P.4    Chan, P.H.5
  • 13
    • 67649852282 scopus 로고    scopus 로고
    • Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion
    • Chen H, Song YS, and Chan PH. Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. J Cereb Blood Flow Metab 29: 1262-1272, 2009..
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1262-1272
    • Chen, H.1    Song, Y.S.2    Chan, P.H.3
  • 16
    • 84861874837 scopus 로고    scopus 로고
    • International, multicenter randomized preclinical trials in translational stroke research: It's time to act
    • Dirnagl U and Fisher M. International, multicenter randomized preclinical trials in translational stroke research: It's time to act. J Cereb Blood Flow Metab 32: 933-935, 2012..
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 933-935
    • Dirnagl, U.1    Fisher, M.2
  • 17
    • 84861648915 scopus 로고    scopus 로고
    • REPRINT: International, multicenter randomized preclinical trials in translational stroke research: It is time to act
    • Dirnagl U and Fisher M. REPRINT: international, multicenter randomized preclinical trials in translational stroke research: it is time to act. Stroke 43: 1453-1454, 2012..
    • (2012) Stroke , vol.43 , pp. 1453-1454
    • Dirnagl, U.1    Fisher, M.2
  • 18
    • 61549104499 scopus 로고    scopus 로고
    • Cautionary insights on knockout mouse studies: The gene or not the gene?
    • Eisener-Dorman AF, Lawrence DA, and Bolivar VJ. Cautionary insights on knockout mouse studies: the gene or not the gene? Brain Behav Immun 23: 318-324, 2009..
    • (2009) Brain Behav Immun , vol.23 , pp. 318-324
    • Eisener-Dorman, A.F.1    Lawrence, D.A.2    Bolivar, V.J.3
  • 19
  • 23
  • 24
    • 33747764829 scopus 로고    scopus 로고
    • Phagocyte-derived reactive species: Salvation or suicide?
    • Halliwell B. Phagocyte-derived reactive species: salvation or suicide? Trends Biochem Sci 31: 509-515, 2006..
    • (2006) Trends Biochem Sci , vol.31 , pp. 509-515
    • Halliwell, B.1
  • 28
    • 33744960694 scopus 로고    scopus 로고
    • NADPH oxidases of the brain: Distribution, regulation, and function
    • Infanger DW, Sharma RV, and Davisson RL. NADPH oxidases of the brain: distribution, regulation, and function. Antioxid Redox Signal 8: 1583-1596, 2006..
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1583-1596
    • Infanger, D.W.1    Sharma, R.V.2    Davisson, R.L.3
  • 29
    • 65349159768 scopus 로고    scopus 로고
    • Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice
    • Jackman KA, Miller AA, De Silva TM, Crack PJ, Drummond GR, and Sobey CG. Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice. Br J Pharmacol 156: 680-688, 2009..
    • (2009) Br J Pharmacol , vol.156 , pp. 680-688
    • Jackman, K.A.1    Miller, A.A.2    De Silva, T.M.3    Crack, P.J.4    Drummond, G.R.5    Sobey, C.G.6
  • 30
    • 67849088501 scopus 로고    scopus 로고
    • Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke
    • Jackman KA, Miller AA, Drummond GR, and Sobey CG. Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke. Brain Res 1286: 215-220, 2009..
    • (2009) Brain Res , vol.1286 , pp. 215-220
    • Jackman, K.A.1    Miller, A.A.2    Drummond, G.R.3    Sobey, C.G.4
  • 34
    • 33847180453 scopus 로고    scopus 로고
    • Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species
    • Kunz A, Anrather J, Zhou P, Orio M, and Iadecola C. Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species. J Cereb Blood Flow Metab 27: 545-551, 2007..
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 545-551
    • Kunz, A.1    Anrather, J.2    Zhou, P.3    Orio, M.4    Iadecola, C.5
  • 40
    • 79954628009 scopus 로고    scopus 로고
    • Betulinic acid protects against cerebral ischemia-reperfusion injury in mice by reducing oxidative and nitrosative stress
    • Lu Q, Xia N, Xu H, Guo L, Wenzel P, Daiber A, Munzel T, Forstermann U, and Li H. Betulinic acid protects against cerebral ischemia-reperfusion injury in mice by reducing oxidative and nitrosative stress. Nitric Oxide Biol Chem 24: 132-138, 2011..
    • (2011) Nitric Oxide Biol Chem , vol.24 , pp. 132-138
    • Lu, Q.1    Xia, N.2    Xu, H.3    Guo, L.4    Wenzel, P.5    Daiber, A.6    Munzel, T.7    Forstermann, U.8    Li, H.9
  • 41
    • 26244444476 scopus 로고    scopus 로고
    • Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
    • Martyn KD, Frederick LM, von Loehneysen K, Dinauer MC, and Knaus UG. Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal 18: 69-82, 2006..
    • (2006) Cell Signal , vol.18 , pp. 69-82
    • Martyn, K.D.1    Frederick, L.M.2    Von Loehneysen, K.3    Dinauer, M.C.4    Knaus, U.G.5
  • 42
    • 27944504319 scopus 로고    scopus 로고
    • NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries
    • Miller AA, Drummond GR, Schmidt HH, and Sobey CG. NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries. Circ Res 97: 1055-1062, 2005..
    • (2005) Circ Res , vol.97 , pp. 1055-1062
    • Miller, A.A.1    Drummond, G.R.2    Schmidt, H.H.3    Sobey, C.G.4
  • 43
    • 33846194681 scopus 로고    scopus 로고
    • Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat
    • Nagel S, Genius J, Heiland S, Horstmann S, Gardner H, and Wagner S. Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat. Brain Res 1132: 210-217, 2007..
    • (2007) Brain Res , vol.1132 , pp. 210-217
    • Nagel, S.1    Genius, J.2    Heiland, S.3    Horstmann, S.4    Gardner, H.5    Wagner, S.6
  • 46
    • 33845620993 scopus 로고    scopus 로고
    • The 'A's and 'O's of NADPH oxidase regulation: A commentary on "subcellular localization and function of alternatively spliced Noxo1 isoforms"
    • Opitz N, Drummond GR, Selemidis S, Meurer S, and Schmidt HH. The 'A's and 'O's of NADPH oxidase regulation: a commentary on "Subcellular localization and function of alternatively spliced Noxo1 isoforms". Free Radic Biol Med 42: 175-179, 2007..
    • (2007) Free Radic Biol Med , vol.42 , pp. 175-179
    • Opitz, N.1    Drummond, G.R.2    Selemidis, S.3    Meurer, S.4    Schmidt, H.H.5
  • 48
    • 49449116792 scopus 로고    scopus 로고
    • Oxidative innate immune defenses by Nox/Duox family NADPH oxidases
    • Rada B and Leto TL. Oxidative innate immune defenses by Nox/Duox family NADPH oxidases. Contrib Microbiol 15: 164-187, 2008..
    • (2008) Contrib Microbiol , vol.15 , pp. 164-187
    • Rada, B.1    Leto, T.L.2
  • 50
    • 0035980160 scopus 로고    scopus 로고
    • Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice
    • Rey FE, Cifuentes ME, Kiarash A, Quinn MT, and Pagano PJ. Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice. Circ Res 89: 408-414, 2001..
    • (2001) Circ Res , vol.89 , pp. 408-414
    • Rey, F.E.1    Cifuentes, M.E.2    Kiarash, A.3    Quinn, M.T.4    Pagano, P.J.5
  • 52
    • 54149094917 scopus 로고    scopus 로고
    • Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition
    • Schluter T, Steinbach AC, Steffen A, Rettig R, and Grisk O. Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition. Cardiovasc Res 80: 271-279, 2008..
    • (2008) Cardiovasc Res , vol.80 , pp. 271-279
    • Schluter, T.1    Steinbach, A.C.2    Steffen, A.3    Rettig, R.4    Grisk, O.5
  • 54
    • 34548475597 scopus 로고    scopus 로고
    • How can we improve the pre-clinical development of drugs for stroke?
    • Sena E, van der Worp HB, Howells D, and Macleod M. How can we improve the pre-clinical development of drugs for stroke? Trends Neurosci 30: 433-439, 2007..
    • (2007) Trends Neurosci , vol.30 , pp. 433-439
    • Sena, E.1    Van Der Worp, H.B.2    Howells, D.3    Macleod, M.4
  • 55
    • 77950572352 scopus 로고    scopus 로고
    • Publication bias in reports of animal stroke studies leads to major overstatement of efficacy
    • Sena ES, van der Worp HB, Bath PM, Howells DW, and Macleod MR. Publication bias in reports of animal stroke studies leads to major overstatement of efficacy. PLoS Biol 8: e1000344, 2010..
    • (2010) PLoS Biol , vol.8
    • Sena, E.S.1    Van Der Worp, H.B.2    Bath, P.M.3    Howells, D.W.4    Macleod, M.R.5
  • 58
    • 80054704273 scopus 로고    scopus 로고
    • NADPH oxidases in cardiovascular disease: Insights from in vivo models and clinical studies
    • Sirker A, Zhang M, and Shah AM. NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies. Basic Res Cardiol 106: 735-747, 2011..
    • (2011) Basic Res Cardiol , vol.106 , pp. 735-747
    • Sirker, A.1    Zhang, M.2    Shah, A.M.3
  • 59
    • 67651184281 scopus 로고    scopus 로고
    • NOX enzymes in the central nervous system: From signaling to disease
    • Sorce S and Krause KH. NOX enzymes in the central nervous system: from signaling to disease. Antioxid Redox Signal 11: 2481-2504, 2009..
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2481-2504
    • Sorce, S.1    Krause, K.H.2
  • 60
    • 0344065373 scopus 로고    scopus 로고
    • Recommendations for standards regarding preclinical neuroprotective and restorative drug development
    • STAIR
    • STAIR. Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 30: 2752-2758, 1999..
    • (1999) Stroke , vol.30 , pp. 2752-2758
  • 61
    • 84859207907 scopus 로고    scopus 로고
    • Offtarget thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[45-d]pyrimidine (VAS2870)
    • Sun QA, Hess DT, Wang B, Miyagi M, and Stamler JS. Offtarget thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3- triazolo[4,5-d]pyrimidine (VAS2870). Free Radic Biol Med 52: 1897-1902, 2012..
    • (2012) Free Radic Biol Med , vol.52 , pp. 1897-1902
    • Sun, Q.A.1    Hess, D.T.2    Wang, B.3    Miyagi, M.4    Stamler, J.S.5
  • 62
    • 46549086942 scopus 로고    scopus 로고
    • Apocynin improves outcome in experimental stroke with a narrow dose range
    • Tang XN, Cairns B, Cairns N, and Yenari MA. Apocynin improves outcome in experimental stroke with a narrow dose range. Neuroscience 154: 556-562, 2008..
    • (2008) Neuroscience , vol.154 , pp. 556-562
    • Tang, X.N.1    Cairns, B.2    Cairns, N.3    Yenari, M.A.4
  • 63
    • 84855360910 scopus 로고    scopus 로고
    • Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke
    • Tang XN, Zheng Z, Giffard RG, and Yenari MA. Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke. Ann Neurol 70: 606-615, 2011..
    • (2011) Ann Neurol , vol.70 , pp. 606-615
    • Tang, X.N.1    Zheng, Z.2    Giffard, R.G.3    Yenari, M.A.4
  • 67
    • 33744509306 scopus 로고    scopus 로고
    • Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus
    • Wang Q, Tompkins KD, Simonyi A, Korthuis RJ, Sun AY, and Sun GY. Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus. Brain Res 1090: 182-189, 2006..
    • (2006) Brain Res , vol.1090 , pp. 182-189
    • Wang, Q.1    Tompkins, K.D.2    Simonyi, A.3    Korthuis, R.J.4    Sun, A.Y.5    Sun, G.Y.6
  • 68
    • 4644360633 scopus 로고    scopus 로고
    • Oxidants, antioxidants and the ischemic brain
    • Warner DS, Sheng H, and Batinic-Haberle I. Oxidants, antioxidants and the ischemic brain. J Exp Biol 207: 3221-3231, 2004..
    • (2004) J Exp Biol , vol.207 , pp. 3221-3231
    • Warner, D.S.1    Sheng, H.2    Batinic-Haberle, I.3


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