Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Yu, Shui Xing ^a   Du, Chong Tao ^a   Chen, Wei ^a   Lei, Qian Qian ^a   Li, Ning ^a   Qi, Shuai ^a   Zhang, Xiao Jing ^a   Hu, Gui Qiu ^a   Deng, Xu Ming ^a   Han, Wen Yu ^a   Yang, Yong Jun ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; CARRIER PROTEIN; CHEMOKINE; CRYOPYRIN; CYTOKINE; FLAGELLIN; GENIPIN; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; ION CHANNEL; IPAF PROTEIN, MOUSE; IRIDOID; LIPOPOLYSACCHARIDE; MITOCHONDRIAL PROTEIN; NLRP3 PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; UCP2 PROTEIN, MOUSE; UNCOUPLING PROTEIN 2;

ANIMAL; AUTOPHAGY; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; MOUSE; PERITONITIS; PNEUMONIA; PROTEIN MULTIMERIZATION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CASPASE 1; CHEMOKINES; CYTOKINES; DISEASE MODELS, ANIMAL; FLAGELLIN; INFLAMMASOMES; ION CHANNELS; IRIDOIDS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PERITONITIS; PNEUMONIA; PROTEIN MULTIMERIZATION; REACTIVE OXYGEN SPECIES; UNCOUPLING PROTEIN 2;

EID: 84949649953     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep17935     Document Type: Article

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