NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against gram-negative bacterial infection

Journal of Immunology

Volumn 188, Issue 11, 2012, Pages 5623-5635

  Cai, Shanshan ^a   Batra, Sanjay ^a   Wakamatsu, Nobuko ^a   Pacher, Pal ^b   Jeyaseelan, Samithamby ^a,c  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; CHEMOKINE; INFLAMMASOME; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; KERATINOCYTE CELL DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 2; NUCLEOTIDE BINDING DOMAIN LEUCINE RICH CONTAINING PROTEIN C4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFLAMMATION; KLEBSIELLA PNEUMONIAE INFECTION; LUNG INFECTION; MOUSE; MUCOSAL IMMUNITY; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURVIVAL RATE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-BINDING PROTEINS; CASPASE 1; FEMALE; HUMANS; IMMUNITY, MUCOSAL; INFLAMMASOMES; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; KLEBSIELLA INFECTIONS; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; PNEUMONIA, BACTERIAL; RESPIRATORY TRACT INFECTIONS;

EID: 84862067214     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200195     Document Type: Article

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