Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions

Nature Communications

Volumn 6, Issue , 2015, Pages

  Nera, Bernadette ^a   Huang, Hui Shun ^a   Lai, Thao ^a   Xu, Lifeng ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER; CELLS AND CELL COMPONENTS; CHROMOSOME; EXPERIMENTAL STUDY; GENE EXPRESSION; GENOMICS; PROTEIN; TUMOR;

ANAPHASE; CHROMOSOME; DNA STRUCTURE; GENE DELETION; GENE OVEREXPRESSION; GENOMIC INSTABILITY; HUMAN; MAMMAL CELL; STOCHASTIC MODEL; TELOMERE; TELOMERE SHORTENING; TUMOR CELL; DNA REPLICATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE TARGETING; GENETICS; HELA CELL LINE; IMMUNOBLOTTING; MCF-7 CELL LINE; METABOLISM; METAPHASE; NEOPLASM; NUCLEOTIDE SEQUENCE; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

MAMMALIA;

TELOMERIC REPEAT BINDING FACTOR 2; TERF2 PROTEIN, HUMAN;

ANAPHASE; BASE SEQUENCE; CELL LINE, TUMOR; DNA REPLICATION; GENE KNOCK-IN TECHNIQUES; GENOMIC INSTABILITY; HELA CELLS; HUMANS; IMMUNOBLOTTING; IN SITU HYBRIDIZATION, FLUORESCENCE; MCF-7 CELLS; METAPHASE; NEOPLASMS; REAL-TIME POLYMERASE CHAIN REACTION; SEQUENCE DELETION; TELOMERE; TELOMERE SHORTENING; TELOMERIC REPEAT BINDING PROTEIN 2;

EID: 84949486692     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10132     Document Type: Article

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