ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice

Journal of Biological Chemistry

Volumn 285, Issue 44, 2010, Pages 34144-34154

  Donkin, James J ^a   Stukas, Sophie ^a   Hirsch Reinshagen, Veronica ^a   Namjoshi, Dhananjay ^a   Wilkinson, Anna ^a   May, Sharon ^a   Chan, Jeniffer ^a   Fan, Jianjia ^a   Collins, Jon ^b   Wellington, Cheryl L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOIDOGENESIS; APOLIPOPROTEIN E (APOE); APOLIPOPROTEINS; ATP-BINDING CASSETTE TRANSPORTERS; BENEFICIAL EFFECTS; BRAIN TISSUE; CEREBRO SPINAL FLUIDS; GENETIC RISKS; LIVER X RECEPTORS; MOUSE MODELS; OVER-EXPRESSION; PROTEIN LEVEL; WILD-TYPE LEVELS;

BRAIN; CHOLESTEROL; LAKES; LIVER; OBJECT RECOGNITION; SILICON SOLAR CELLS; TRANSCRIPTION;

GLYCOPROTEINS;

3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; ABC TRANSPORTER A1; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN TISSUE; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; LOW DRUG DOSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN METABOLISM; RECOGNITION; WILD TYPE;

AMYLOID; ANIMALS; APOLIPOPROTEINS E; ATP-BINDING CASSETTE TRANSPORTERS; BENZOIC ACIDS; BENZYLAMINES; FEMALE; HIPPOCAMPUS; HUMANS; MEMORY; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; ORPHAN NUCLEAR RECEPTORS; PATTERN RECOGNITION, VISUAL; PRESENILIN-1;

MUS;

EID: 77958594257     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.108100     Document Type: Article

References (43)

1. Fan, J., Donkin, J., and Wellington, C. L. (2009) Biofactors 35, 239-248
2. Morris, J. C. (1997) Neurology 49, (suppl.) S7-S10
3. Yankner, B. A., and Lu, T. (2009) J. Biol. Chem. 284, 4755-4759
4. Hardy, J. (1997) Trends Neurosci. 20, 154-159
5. Bates, K. A., Verdile, G., Li, Q. X., Ames, D., Hudson, P., Masters, C. L., and Martins, R. N. (2009) Mol. Psychiatry 14, 469-486
6. Hirsch-Reinshagen, V., Zhou, S., Burgess, B. L., Bernier, L., McIsaac, S. A., Chan, J. Y., Tansley, G. H., Cohn, J. S., Hayden, M. R., and Wellington, C. L. (2004) J. Biol. Chem. 279, 41197-41207
7. Hirsch-Reinshagen, V., Maia, L. F., Burgess, B. L., Blain, J. F., Naus, K. E., McIsaac, S. A., Parkinson, P. F., Chan, J. Y., Tansley, G. H., Hayden, M. R., Poirier, J., Van Nostrand, W. E., and Wellington, C. L. (2005) J. Biol. Chem. 280, 43243-43256
8. Wahrle, S. E., Jiang, H., Parsadanian, M., Hartman, R. E., Bales, K. R., Paul, S. M., and Holtzman, D. M. (2005) J. Biol. Chem. 280, 43236-43242
9. Wahrle, S. E., Jiang, H., Parsadanian, M., Legleiter, J., Han, X., Fryer, J. D., Kowalewski, T., and Holtzman, D. M. (2004) J. Biol. Chem. 279, 40987-40993
10. Wahrle, S. E., Jiang, H., Parsadanian, M., Kim, J., Li, A., Knoten, A., Jain, S., Hirsch-Reinshagen, V., Wellington, C. L., Bales, K. R., Paul, S. M., and Holtzman, D. M. (2008) J. Clin. Invest. 118, 671-682
11. Koldamova, R., Staufenbiel, M., and Lefterov, I. (2005) J. Biol. Chem. 280, 43224-43235
12. Koldamova, R. P., Lefterov, I. M., Lefterova, M. I., and Lazo, J. S. (2001) Biochemistry 40, 3553-3560
13. Jiang, Q., Lee, C. Y., Mandrekar, S., Wilkinson, B., Cramer, P., Zelcer, N., Mann, K., Lamb, B., Willson, T. M., Collins, J. L., Richardson, J. C., Smith, J. D., Comery, T. A., Riddell, D., Holtzman, D. M., Tontonoz, P., and Landreth, G. E. (2008) Neuron 58, 681-693
14. Burns, M. P., Vardanian, L., Pajoohesh-Ganji, A., Wang, L., Cooper, M., Harris, D. C., Duff, K., and Rebeck, G. W. (2006) J. Neurochem. 98, 792-800
15. Dietschy, J. M., and Turley, S. D. (2001) Curr. Opin. Lipidol. 12, 105-112
16. Ladu, M. J., Reardon, C., Van Eldik, L., Fagan, A. M., Bu, G., Holtzman, D., and Getz, G. S. (2000) Ann. N. Y. Acad. Sci. 903, 167-175
17. Genest, J., Jr., Marcil, M., Denis, M., and Yu, L. (1999) J. Investig. Med. 47, 31-42
18. Rust, S., Rosier, M., Funke, H., Real, J., Amoura, Z., Piette, J. C., Deleuze, J. F., Brewer, H. B., Duverger, N., Denèfle, P., and Assmann, G. (1999) Nat. Genet. 22, 352-355
19. Bodzioch, M., Orsó, E., Klucken, J., Langmann, T., Böttcher, A., Diederich, W., Drobnik, W., Barlage, S., Büchler, C., Porsch-Ozcürümez, M., Kaminski, W. E., Hahmann, H. W., Oette, K., Rothe, G., Aslanidis, C., Lackner, K. J., and Schmitz, G. (1999) Nat. Genet. 22, 347-351
20. Brooks-Wilson, A., Marcil, M., Clee, S. M., Zhang, L. H., Roomp, K., van Dam, M., Yu, L., Brewer, C., Collins, J. A., Molhuizen, H. O., Loubser, O., Ouellette, B. F., Fichter, K., Ashbourne-Excoffon, K. J., Sensen, C. W., Scherer, S., Mott, S., Denis, M., Martindale, D., Frohlich, J., Morgan, K., Koop, B., Pimstone, S., Kastelein, J. J., Genest, J., Jr., and Hayden, M. R. (1999) Nat. Genet. 22, 336-345
21. Beaven, S. W., and Tontonoz, P. (2006) Annu. Rev. Med. 57, 313-329
22. Wójcicka, G., Jamroz-Wisniewska, A., Horoszewicz, K., and Beltowski, J. (2007) Postepy Hig. Med. Dosw. 61, 736-759
23. Jamroz-Wisniewska, A., Wójcicka, G., Horoszewicz, K., and Beltowski, J. (2007) Postepy Hig. Med. Dosw. 61, 760-785
24. Zelcer, N., Khanlou, N., Clare, R., Jiang, Q., Reed-Geaghan, E. G., Landreth, G. E., Vinters, H. V., and Tontonoz, P. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 10601-10606
25. Schultz, J. R., Tu, H., Luk, A., Repa, J. J., Medina, J. C., Li, L., Schwendner, S., Wang, S., Thoolen, M., Mangelsdorf, D. J., Lustig, K. D., and Shan, B. (2000) Genes Dev. 14, 2831-2838
26. Lund, E. G., Peterson, L. B., Adams, A. D., Lam, M. H., Burton, C. A., Chin, J., Guo, Q., Huang, S., Latham, M., Lopez, J. C., Menke, J. G., Milot, D. P., Mitnaul, L. J., Rex-Rabe, S. E., Rosa, R. L., Tian, J. Y., Wright, S. D., and Sparrow, C. P. (2006) Biochem. Pharmacol. 71, 453-463
27. Miao, B., Zondlo, S., Gibbs, S., Cromley, D., Hosagrahara, V. P., Kirchgessner, T. G., Billheimer, J., and Mukherjee, R. (2004) J. Lipid Res. 45, 1410-1417
28. Koldamova, R. P., Lefterov, I. M., Staufenbiel, M., Wolfe, D., Huang, S., Glorioso, J. C., Walter, M., Roth, M. G., and Lazo, J. S. (2005) J. Biol. Chem. 280, 4079-4088
29. Riddell, D. R., Zhou, H., Comery, T. A., Kouranova, E., Lo, C. F., Warwick, H. K., Ring, R. H., Kirksey, Y., Aschmies, S., Xu, J., Kubek, K., Hirst, W. D., Gonzales, C., Chen, Y., Murphy, E., Leonard, S., Vasylyev, D., Oganesian, A., Martone, R. L., Pangalos, M. N., Reinhart, P. H., and Jacobsen, J. S. (2007) Mol. Cell. Neurosci. 34, 621-628
30. Vanmierlo, T., Rutten, K., Dederen, J., Bloks, V. W., van Vart-van der Zee, L. C., Kuipers, F., Kiliaan, A., Blokland, A., Sijbrands, E. J. G., Steinbusch, H., Prickaerts, J., Lutjohann, D., and Mulder, M. (2009) Neurobiol. Aging
31. Groot, P. H., Pearce, N. J., Yates, J. W., Stocker, C., Sauermelch, C., Doe, C. P., Willette, R. N., Olzinski, A., Peters, T., d'Epagnier, D., Morasco, K. O., Krawiec, J. A., Webb, C. L., Aravindham, K., Jucker, B., Burgert, M., Ma, C., Marino, J. P., Collins, J. L., Macphee, C. H., Thompson, S. K., and Jaye, M. (2005) J. Lipid Res. 46, 2182-2191
32. Jankowsky, J. L., Fadale, D. J., Anderson, J., Xu, G. M., Gonzales, V., Jenkins, N. A., Copeland, N. G., Lee, M. K., Younkin, L. H., Wagner, S. L., Younkin, S. G., and Borchelt, D. R. (2004) Hum. Mol. Genet. 13, 159-170
33. Hamon, Y., Broccardo, C., Chambenoit, O., Luciani, M. F., Toti, F., Chaslin, S., Freyssinet, J. M., Devaux, P. F., McNeish, J., Marguet, D., and Chimini, G. (2000) Nat. Cell Biol. 2, 399-406
34. Ennaceur, A., and Delacour, J. (1988) Behav. Brain Res. 31, 47-59
35. Walf, A. A., Rhodes, M. E., and Frye, C. A. (2006) Neurobiol. Learn Mem. 86, 35-46
36. Morris, R. (1984) J. Neurosci. Methods 11, 47-60
37. DeMattos, R. B., Bales, K. R., Parsadanian, M., O'Dell, M. A., Foss, E. M., Paul, S. M., and Holtzman, D. M. (2002) J. Neurochem. 81, 229-236
38. Chang, K. A., and Suh, Y. H. (2005) J. Pharmacol. Sci. 97, 461-471
39. Glabe, C. G. (2008) J. Biol. Chem. 283, 29639-29643
40. Bellgowan, P. S., Buffalo, E. A., Bodurka, J., and Martin, A. (2009) Learn. Mem. 16, 433-438
41. Grimm, M. O., Grimm, H. S., Pätzold, A. J., Zinser, E. G., Halonen, R., Duering, M., Tschäpe, J. A., De Strooper, B., Müller, U., Shen, J., and Hartmann, T. (2005) Nat. Cell Biol. 7, 1118-1123
42. Lefterov, I., Bookout, A., Wang, Z., Staufenbiel, M., Mangelsdorf, D., and Koldamova, R. (2007) Mol. Neurodegener. 2, 20
43. Mahley, R. W., and Rall, S. C., Jr. (2000) Annu. Rev. Genomics Hum. Genet 1, 507-537