Cholinergic abnormalities, endosomal alterations and up-regulation of nerve growth factor signaling in Niemann-Pick Type C Disease

Molecular Neurodegeneration

Volumn 7, Issue 1, 2012, Pages

  Cabeza, Carolina ^a,b   Figueroa, Alicia ^a,b   Lazo, Oscar M ^a,b   Galleguillos, Carolina ^a,b   Pissani, Claudia ^a,b   Klein, Andrés ^a   Gonzalez Billault, Christian ^c   Inestrosa, Nibaldo C ^a,b   Alvarez, Alejandra R ^a   Zanlungo, Silvana ^a   Bronfman, Francisca C ^a,b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b Center for Aging and Regeneration (CARE)   (Chile)

^c UNIVERSITY OF CHILE   (Chile)

Author keywords

Cholesterol; cholinergic system; Endosomes; NGF; Niemann Pick type C1; PC12

Indexed keywords

3BETA (2 DIETHYLAMINOETHOXY)ANDROST 5 EN 17 ONE; CHOLINE ACETYLTRANSFERASE; NERVE GROWTH FACTOR; NEUROTROPHIN; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN HOMOGENATE; CELL LEVEL; CELL SIZE; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOCYTOSIS; ENDOSOME; ENZYME PHOSPHORYLATION; FOREBRAIN; LYSOSOME; MOUSE; NERVE DEGENERATION; NERVE FIBER TRANSECTION; NIEMANN PICK DISEASE; NONHUMAN; PHENOTYPE; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BRAIN; CELL STRAIN; CHOLINERGIC NERVE; CONFOCAL MICROSCOPY; DISEASE MODEL; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; RAT;

MUS;

ANIMALS; BRAIN; CHOLINERGIC FIBERS; DISEASE MODELS, ANIMAL; ENDOSOMES; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NERVE DEGENERATION; NERVE GROWTH FACTOR; NIEMANN-PICK DISEASE, TYPE C; PC12 CELLS; RATS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84858979445     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-7-11     Document Type: Article

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