Observations in THY-Tau22 mice that resemble behavioral and psychological signs and symptoms of dementia

Behavioural Brain Research

Volumn 242, Issue 1, 2013, Pages 34-39

  Van der Jeugd, Ann ^a   Blum, David ^b,c,d   Raison, Sylvie ^e   Eddarkaoui, Sabiha ^b,c   Buée, Luc ^b,c,d   D'Hooge, Rudi ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^c UNIV LILLE   (France)

^d LILLE UNIVERSITY HOSPITAL   (France)

^e CNRS   (France)

Author keywords

5 HT; Activity; Aggression; Alzheimer's disease; BPSD; Depression; Tau aggregates

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; SEROTONIN; TAU PROTEIN;

5 HYDROXYINDOLEACETIC ACID BRAIN LEVEL; AGGRESSION; AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR CHANGE; BEHAVIOR DISORDER; BEHAVIORAL AND PSYCHOLOGICAL SIGN AND SYMPTOM OF DEMENTIA; BEHAVIORAL SCIENCE; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; DEPRESSION; DISEASE CONTROL; DISEASE EXACERBATION; EXPERIMENTAL MODEL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; LIMBIC SYSTEM; MALE; MENTAL DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SEROTONIN BRAIN LEVEL; SYMPTOMATOLOGY;

AGGRESSION; ANIMALS; BEHAVIORAL SYMPTOMS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEMENTIA; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; INDOLES; MALE; MICE; MICE, TRANSGENIC; MOTOR ACTIVITY; MUTATION; PSYCHOMOTOR AGITATION; SEROTONIN; TAU PROTEINS;

EID: 84872228584     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2012.12.008     Document Type: Article

References (60)

1. American Psychiatric Association Diagnostic and statistical manual of mental disorders 2000, American Psychiatric Association, Washington, DC. 4th ed. (text rev.).
2. Amieva H., Jacqmin-Gadda H., Orgogozo J.M., Le Carret N., Helmer C., Letenneur L., et al. The 9 year cognitive decline before dementia of the Alzheimer type: a prospective population-based study. Brain 2005, 128:1093-1111.
3. Jacobs D.M., Sano M., Dooneief G., Marder K., Bell K.L., Stern Y. Neuropsychological detection and characterization of preclinical Alzheimer's disease. Neurology 1995, 45:957-962.
4. Graham N.L., Emery T., Hodges J.R. Distinctive cognitive profiles in Alzheimer's disease and subcortical vascular dementia. Journal of Neurology, Neurosurgery & Psychiatry 2004, 75:61-71.
5. Reisberg B., Borenstein J., Salob S.P., Ferris S.H., Franssen E., Georgotas A. Behavioural symptoms in Alzheimer's disease: phenomenology and treatment. Journal of Clinical Psychiatry 1987, 48:9-15.
6. Chung J.A., Cummings J.L. Neurobehavioural and neuropsychiatric symptoms in Alzheimer's disease. Neurologic Clinics 2000, 18:829-846.
7. Frisoni G.B., Rozzini L., Gozetti A., Binetti G., Zanetti O., Bianchetti A., et al. Behavioural syndromes in Alzheimer's disease: description and c correlates. Dementia and Geriatric Cognitive Disorders 1999, 10:130-138.
8. Finkel S.I. Behavioural and psychological symptoms of dementia. Clinics in Geriatric Medicine 2003, 19:799-824.
9. Ballard C.G., Gauthier S., Cummings J.L., Brodaty H., Grossberg G.T., Robert P. Management of agitation and aggression associated with Alzheimer disease. Nature Reviews Neurology 2009, 5:245-255.
10. Burns A., Jacoby R., Levy R. Psychiatric phenomena in Alzheimer's disease. IV: disorders of behaviour. British Journal of Psychiatry 1990, 157:92-94.
11. Ryden M.B. Aggressive behaviour in persons with dementia who live in the community. Alzheimer Disease and Associated Disorders 1988, 2(4):342-355.
12. Visser P.J., Verhey F.R., Ponds R.W., Kester A., Jolles J. Distinction between preclinical Alzheimer's disease and depression. Journal of the American Geriatrics Society 2000, 48:479-484.
13. Geerlings M.I., den Heijer T., Koudstaal P.J., Hofman A., Breteler M.M. History of depression, depressive symptoms, and medial temporal lobe atrophy and the risk of Alzheimer disease. Neurology 2008, 70:1258-1264.
14. Elder G.A., Gama Sosa M.A., De Gasperi R. Transgenic mouse models of Alzheimer's disease. Mount Sinai Journal of Medicine 2010, 77(1):69-81.
15. Bryan K.J., Lee H., Perry G., Smith M.A., Casadesus G. Transgenic mouse models of Alzheimer's disease: behavioural testing and considerations. Methods of behaviour analysis in neuroscience 2009, CRC Press, Boca Raton (FL), [Chapter 1]. 2nd edition. J.J. Buccafusco (Ed.).
16. Chin J. Selecting a mouse model of Alzheimer's disease. Methods in Molecular Biology 2011, 670:169-189.
17. Hall A.M., Roberson E.D. Mouse models of Alzheimer's disease. Brain Research Bulletin 2011, 88(1):3-12.
18. Schaeffer E.L., Figueiro M., Gattaz W.F. Insights into Alzheimer disease pathogenesis from studies in transgenic animal models. Clinics (Sao Paulo) 2011, 66(Suppl. 1):45-54.
19. Lalonde R., Fukuchi K., Strazielle C. APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD). Neuroscience and Biobehavioral Reviews 2012, 36(5):1357-1375.
20. Ittner L.M., Götz J. Amyloid-β and tau-a toxic pas de deux in Alzheimer's disease. Nature Reviews Neuroscience 2011, 12(2):65-72.
21. Schindowski K., Bretteville A., Leroy K., Begard S., Brion J.P., Hamdane M., et al. Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits. American Journal of Pathology 2006, 169:599-616.
22. Belarbi K., Burnouf S., Fernandez-Gomez F.J., Desmercières J., Troquier L., Brouillette J., et al. Loss of medial septum cholinergic neurons in THY-Tau22 mouse model: what links with tau pathology?. Current Alzheimer Research 2011, 8(6):633-638.
23. Belarbi K., Burnouf S., Fernandez-Gomez F.J., Laurent C., Lestavel S., Figeac M., et al. Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology. Neurobiology of Disease 2011, 43(2):486-494.
24. Van der Jeugd A., Ahmed T., Burnouf S., Belarbi K., Hamdame M., Grosjean M.E., et al. Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission. Neurobiology of Learning and Memory 2011, 95:296-304.
25. Bowen D.M., Najlerahim A., Procter A., Francis P., Murphy E. Circumscribed changes of the cerebral cortex in neuropsychiatric disorders of late life. Proceedings of the National Academy of Sciences of the United States of America 1989, 86:9504-9508.
26. Cheetham S., Crompton M., Katona C., Horton R. Brain 5-HT2 receptor binding sites in depressed suicide victims. Brain Research 1988, 443:272-280.
27. Gross-Isseroff R., Salama D., Isreli M., Biegon A. Autoradiographic analysis of [3H]ketansterin binding in the human brain postmortem: effect of suicide. Brain Research 1990, 507:208-215.
28. Lyness S.A., Zarow C., Chui H.C. Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis. Neurobiology of Aging 2003, 24(1):1-23.
29. Whitford G.M. Alzheimer's disease and serotonin: a review. Neuropsychobiology 1986, 15(3-4):133-142.
30. Mehlman P.T., Higley J.D., Faucher I., Lilly A.A., Taub D.M., Vickers J., et al. LowCSF 5-HIAA concentrations and severe aggression and impaired impulse control in nonhuman primates. American Journal of Psychiatry 1994, 151:485-491.
31. Westergaard G.C., Suomi S.J., Chavanne T.J., Houser L., Hurley A., Cleveland A., et al. Physiological correlates of aggression and impulsivity in free-ranging female primates. Neuropsychopharmacology 2003, 28:1045-1055.
32. Messeri P., Eleftheriou B.E., Oliverio A. Dominance behaviour: a phylogenetic analysis in the mouse. Physiology and Behavior 1975, 14:53-58.
33. Steru L., Chermat R., Thierry B., Simon P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology 1985, 85:367-370.
34. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 1951, 193:265-275.
35. Scarmeas N., Brandt J., Blacker D., Albert M., Hadjigeorgiou G., Dubois B., et al. Disruptive behaviour as a predictor in Alzheimer disease. Archives of Neurology 2007, 64:1755-1761.
36. Ancoli-Israel S., Klauber M.R., Gillin J.C., Campbell S.S., Hofstetter C.R. Sleep in non-institutionalized Alzheimer's disease patients. Aging 1994, 6:451-458.
37. Vloeberghs E., Van Dam D., Engelborghs S., Nagels G., Staufenbiel M., De Deyn P.P. Altered circadian locomotor activity in APP23 mice: a model for BPSD disturbances. European Journal of Neuroscience 2004, 20:2757-2766.
38. Ambrée O., Touma C., Görtz N., Keyvani K., Paulus W., Palme R., et al. Activity changes and marked stereotypic behaviour precede Abeta pathology in TgCRND8 Alzheimer mice. Neurobiology of Aging 2006, 27:955-964.
39. Sterniczuk R., Dyck R.H., Laferla F.M., Antle M.C. Characterization of the 3×Tg-AD mouse model of Alzheimer's disease: circadian changes. Brain Research 2010, 1348:139-148.
40. Kalueff A.V., Jensen C.L., Murphy D.L. Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice. Brain Research 2007, 1169:87-97.
41. Jansen F., Heiming R.S., Lewejohann L., Touma C., Palme R., Schmitt A., et al. Modulation of behavioural profile and stress response by 5-HTT genotype and social experience in adulthood. Behavioural Brain Research 2010, 207(1):21-29.
42. Moechars D., Filis M., Kuiperi C., Laenen I., Van Leuven F. Aggressive behaviour in transgenic mice expressing APP is alleviated by serotonergic drugs. Neuroreport 1998, 9:3561-3564.
43. Kumar-Singh S., Dewachter I., Moechars D., Lübke U., De Jonghe C., Ceuterick C., et al. Behavioural disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation. Neurobiology of Disease 2000, 7:9-22.
44. Minkeviciene R., Banerjee P., Tanila H. Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease. Journal of Pharmacology and Experimental Therapeutics 2004, 311:677-682.
45. Pugh P.L., Richardson J.C., Bate S.T., Upton N., Sunter D. Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease. Behavioural Brain Research 2007, 178:18-28.
46. Vloeberghs E., Van Dam D., Coen K., Staufenbiel M., De Deyn P.P. Aggressive male APP23 mice modeling behavioural alterations in dementia. Behavioral Neuroscience 2006, 120:1380-1383.
47. Porsolt R.D., Brossard G., Hautbois C., Roux S. Rodent models of depression: forced swimming and tail suspension behavioural despair tests in rats and mice. Current Protocols in Neuroscience 2001, 8. 8.10A.
48. Cryan J.F., Mombereau C., Vassout A. The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neuroscience and Biobehavioral Reviews 2005, 29(4-5):571-625.
49. Anisman H., Matheson K. Stress, depression, and anhedonia: caveats concerning animal models. Neuroscience and Biobehavioral Reviews 2005, 29(4-5):525-546.
50. Papp M., Willner P., Muscat R. An animal model of anhedonia: attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress. Psychopharmacology 1991, 104(2):255-259.
51. Kennett G. Mechanisms of serotonergic affect control. Kynurenine and serotonin pathways 1991, 231-243. Plenum Press, New York. R. Schwarcz, S. Young, R. Brown (Eds.).
52. Meltzer H. Role of serotonin in depression. Annals of the New York Academy of Sciences 1990, 600:486-500.
53. Staner L., Kempanaers C., Simonnet M.P., Fransolet L., Mendlewicz J. 5-HT2 receptor antagonism and slowwave sleep in major depression. Acta Psychiatrica Scandinavica 1992, 86:133-137.
54. Filali M., Lalonde R., Rivest S. Cognitive and non-cognitive behaviours in an APPswe/PS1 bigenic model of Alzheimer's disease. Genes, Brain and Behavior 2009, 8:143-148.
55. Mosienko V., Bert B., Beis D., Matthes S., Fink H., Bader M., et al. Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin. Translational Psychiatry 2012, 10.1038/tp.2012.44.
56. Stockmeier C.A., Dilley G.E., Shapiro L.A., Overholser J.C., Thompson P.A., Meltzer H.Y. Serotonin receptors in suicide victims with major depression. Neuropsychopharmacology 1997, 16(2):162-173.
57. Larson J., Jessen R.E., Uz T., Arslan A.D., Kurtuncu M., Imbesi M., et al. Impaired hippocampal long-term potentiation in melatonin MT2 receptor-deficient mice. Neuroscience Letters 2006, 393(1):23-26.
58. Wang L.M., Suthana N.A., Chaudhury D., Weaver D.R., Colwell C.S. Melatonin inhibits hippocampal long-term potentiation. European Journal of Neuroscience 2005, 22(9):2231-2237.
59. Zarros ACh, Kalopita K.S., Tsakiris S.T. Serotoninergic impairment and aggressive behavior in Alzheimer's disease. Acta Neurobiological Experiments (Wars) 2005, 65(3):277-286.
60. Volicer L., Harper D., Manning B., Goldstein R., Satlin A. Sundowning and circadian rhythms in Alzheimer's disease. American Journal of Psychiatry 2001, 158(5):704-711.