TGF-β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment

GLIA

Volumn 60, Issue 7, 2012, Pages 1160-1171

  Abutbul, Shai ^a   Shapiro, Jenny ^a   Szaingurten Solodkin, Irit ^a   Levy, Nitzan ^a   Carmy, Yaron ^a   Baron, Rona ^a   Jung, Steffen ^b   Monsonego, Alon ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Chemokine CX3CR1; Differentiation; Microglia; TGF

Indexed keywords

ACTIVIN RECEPTOR 1; CD11B ANTIGEN; CD86 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; GLYCOPROTEIN P 15095; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; SMAD2 PROTEIN; SMAD3 PROTEIN; STEM CELL FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOWN REGULATION; EX VIVO STUDY; HIPPOCAMPUS; INFLAMMATION; MICROGLIA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; COCULTURE TECHNIQUES; MICE; MICROGLIA; PHOSPHORYLATION; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84860666662     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22343     Document Type: Article

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