Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

PLoS Pathogens

Volumn 10, Issue 4, 2014, Pages

  Schneider, Christoph ^a   Nobs, Samuel P ^a   Heer, Alex K ^a   Kurrer, Michael ^b   Klinke, Glynis ^c   van Rooijen, Nico ^d   Vogel, Johannes ^e   Kopf, Manfred ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G2A; MEMBRANE PROTEIN; CD131 ANTIGEN; CSF2RB1 PROTEIN, MOUSE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL OXYGEN SATURATION; ARTICLE; AUTOFLUORESCENCE; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE SEVERITY; FETUS; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HISTOLOGY; HYPOXIA; INFLUENZA; LUNG ALVEOLUS MACROPHAGE; LUNG GAS EXCHANGE; MICROARRAY ANALYSIS; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; PHAGOCYTOSIS; RESPIRATORY FAILURE; SURVIVAL; UPREGULATION; VIRAL CLEARANCE; VIRUS LOAD; ANIMAL; CD8+ T LYMPHOCYTE; DENDRITIC CELL; GENETICS; IMMUNOLOGY; INFLUENZA VIRUS A H1N1; KNOCKOUT MOUSE; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; VIROLOGY;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINE RECEPTOR COMMON BETA SUBUNIT; DENDRITIC CELLS; IMMUNITY, CELLULAR; INFLUENZA A VIRUS, H1N1 SUBTYPE; MACROPHAGES, ALVEOLAR; MICE; MICE, KNOCKOUT; ORTHOMYXOVIRIDAE INFECTIONS; PPAR GAMMA; RESPIRATORY INSUFFICIENCY;

EID: 84901379724     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004053     Document Type: Article

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