Deoxyandrographolide promotes glucose uptake through glucose transporter-4 translocation to plasma membrane in L6 myotubes and exerts antihyperglycemic effect in vivo

European Journal of Pharmacology

Volumn 768, Issue , 2015, Pages 207-216

  Arha, Deepti ^a,b   Pandeti, Sukanya ^a   Mishra, Akansha ^a,b   Srivastava, Swayam Prakash ^a   Srivastava, Arvind Kumar ^a,b   Narender, Tadigoppula ^a,b   Tamrakar, Akhilesh Kumar ^a,b  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

Author keywords

Andrographis paniculata; Glucose uptake; GLUT4 translocation; Insulin resistance; Skeletal muscle

Indexed keywords

ANDROGRAPHOLIDE; ANTIDIABETIC AGENT; DEOXYANDROGRAPHOLIDE; GLUCOSE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; 14-DEOXYANDROGRAPHOLIDE; DITERPENE;

ANDROGRAPHIS PANICULATA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; DOSE RESPONSE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; IN VIVO STUDY; INSULIN BLOOD LEVEL; MYOTUBE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PHYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; CELL LINE; CYTOLOGY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; MALE; METABOLISM; MOUSE; PATHOLOGY; SKELETAL MUSCLE CELL;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL LINE; CELL MEMBRANE; DIABETES MELLITUS, EXPERIMENTAL; DITERPENES; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HYPOGLYCEMIC AGENTS; MALE; MICE; MUSCLE FIBERS, SKELETAL; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN TRANSPORT; RATS; SIGNAL TRANSDUCTION;

EID: 84947608261     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.10.055     Document Type: Article

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