Diastereomeric mixture of calophyllic acid and isocalophyllic acid stimulates glucose uptake in skeletal muscle cells: Involvement of PI-3-Kinase- and ERK1/2-dependent pathways

Molecular and Cellular Endocrinology

Volumn 370, Issue 1-2, 2013, Pages 11-19

  Prasad, Janki ^a   Maurya, Chandan Kumar ^a   Pandey, Jyotsana ^a   Jaiswal, Natasha ^a   Madhur, Gaurav ^a   Srivastava, Arvind Kumar ^a   Narender, Tadigoppula ^a   Tamrakar, Akhilesh Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Calophyllum inophyllum; Glucose uptake; Insulin resistance; Skeletal muscle

Indexed keywords

5' AMP ACTIVATED KINASE; ANTIDIABETIC AGENT; CALOPHYLLIC ACID; F 015; INSULIN; ISOCALOPHYLLIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PLANT MEDICINAL PRODUCT; PROTEIN AS160; PROTEIN KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; UPREGULATION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BIOLOGICAL TRANSPORT; CALOPHYLLUM; CELL LINE; CELL MEMBRANE; CHROMONES; DEXAMETHASONE; DIABETES MELLITUS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; GTPASE-ACTIVATING PROTEINS; HUMANS; INSULIN; INSULIN RESISTANCE; MAP KINASE SIGNALING SYSTEM; MICE; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 84876361256     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.02.013     Document Type: Article

References (45)

1. Andrews R.C., Walker B.R. Glucocorticoids and insulin resistance: old hormone, new targets. Clin. Sci. 1999, 96:513-523.
2. Ayyanar M., Ignacimuthu S. Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India. J. Ethnopharmacol. 2011, 134:851-864.
3. Bandyopadhyay G., Sajan M.P., Kanoh Y., Standaert M.L., Quon M.J., Reed B.C., Dikic I., Farese R.V. Glucose activates protein kinase C-zeta/lambda through proline-rich tyrosine kinase-2, extracellular signal-regulated kinase, and phospholipase D: a novel mechanism for activating glucose transporter translocation. J. Biol. Chem. 2001, 276:35537-35545.
4. Bryant N.J., Govers R., James D.E. Regulated transport of the glucose transporter GLUT4. Nature Rev. Mol. Cell Biol. 2002, 3:267-277.
5. Cechinel Filho V., Meyre-Silva C., Niero R. Chemical and pharmacological aspects of the genus Calophyllum. Chem. Biodiv. 2009, 6:313-327.
6. Chan J.C., Malik V., Jia W., Kadowaki T., Yajnik C.S., Yoon K.H., Hu F.B. Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA 2009, 301:2129-2140.
7. DeFronzo R.A., Jacot E., Jequier E., Maeder E., Wahren J., Felber J.P. The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 1981, 30:1000-1007.
8. Deslypere J.P. The role of HMG-CoA reductase inhibitors in the treatment of hyperlipidemia: a review of fluvastatin. Curr. Ther. Res. 1995, 56:111-128.
9. Favata M.F., Horiuchi K.Y., Manos E.J., Daulerio A.J., Stradley D.A., Feeser W.S., van Dyk D.E., Pitts W.J., Earl R.A., Hobbs F., Copeland R.A., Magolda R.L., Scherle P.A., Trzaskos J.M. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 1998, 273:18623-18632.
10. Fisher J.S. Potential role of the AMP-activated protein kinase in regulation of insulin action. Cell Sci. 2006, 28:68-81.
11. Fryer L.G.D., Parbu-Patel A., Carling D. The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J. Biol. Chem. 2002, 277:25226-25232.
12. Ghaisas M., Navghare V., Takawale A., Zope V., Tanwar M., Deshpande A. Effect of Tectona grandis Linn. on dexamethasone-induced insulin resistance in mice. J. Ethnopharmacol. 2009, 122:304-307.
13. Girón M.D., Sevillano N., Vargas A.M., Domínguez J., Guinovart J.J., Salto R. The glucose-lowering agent sodium tungstate increases the levels and translocation of GLUT4 in L6 myotubes through a mechanism associated with ERK1/2 and MEF2D. Diabetologia 2008, 51:1285-1295.
14. Hawley S.A., Gadalla A.E., Olsen G.S., Hardie D.G. The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes 2002, 51:2420-2425.
15. Heart E., Sung C.K. Insulin-like and non-insulin-like selenium actions in 3T3-L1 adipocytes. J. Cell. Biochem. 2003, 88:719-731.
16. Herman M.A., Kahn B.B. Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. J. Clin. Invest. 2006, 116:1767-1775.
17. Huang S., Czech M.P. The GLUT4 glucose transporter. Cell. Metab. 2007, 5:237-252.
18. Huang Y.C., Chang W.L., Huang S.F., Lin C.Y., Lin H.C., Chang T.C. Pachymic acid stimulates glucose uptake through enhanced GLUT4 expression and translocation. Eur. J. Pharmacol. 2010, 648:39-49.
19. Itoigawa M., Ito C., Tan H.T., Kuchide M., Tokuda H., Nishino H., Furukawa H. Cancer chemopreventive agents, 4-phenylcoumarins from Calophyllum inophyllum. Cancer Lett. 2001, 169:15-19.
20. Jaiswal N., Yadav P.P., Maurya R., Srivastava A.K., Tamrakar A.K. Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner. Eur. J. Pharmacol. 2011, 670:22-28.
21. Khan A.H., Pessin J.E. Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways. Diabetologia 2002, 45:1475-1483.
22. Kishi K., Muromoto N., Nakaya Y., Miyata I., Hagi A., Hayashi H., Ebina Y. Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway. Diabetes 1998, 47:550-558.
23. Kurth-Kraczek E.J., Hirshman M.F., Goodyear L.J., Winder W.W. 5'-AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle. Diabetes 1999, 48:1666-1671.
24. Lakshmi B.S., Sujatha S., Anand S., Sangeetha K.N., Narayanan R.B., Katiyar C., Kanaujia A., Duggar R., Singh Y., Srinivas K., Bansal V., Sarin S., Tandon R., Sharma S., Singh S. Cinnamic acid, from the bark of Cinnamomum cassia, regulates glucose transport via activation of GLUT4 on L6 myotubes in a phosphatidylinositol 3-kinase-independent manner. J. Diab. 2009, 1:99-106.
25. Laure F., Raharivelomanana P., Butaud J.F., Bianchini J.P., Gaydou E.M. Screening of anti-HIV-1 inophyllums by HPLC-DAD ofCalophyllum inophyllum leaf extracts from French Polynesia Islands. Anal. Chim. Acta 2008, 624:147-153.
26. Li H.B., Ge Y.K., Zheng X.X., Zhang L. Salidroside stimulated glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase. Eur. J. Pharmacol. 2008, 588:165-169.
27. Malide D., Cushman S.W. Morphological effects of wortmannin on the endosomal system and GLUT4-containing compartments in rat adipose cells. J. Cell. Sci. 1997, 110:2795-2806.
28. Moller D.E. New drug targets for type 2 diabetes and the metabolic syndrome. Nature 2001, 414:821-827.
29. Ngo S., Barry J.B., Nisbet J.C., Prins J.B., Whitehead J.P. Reduced phosphorylation of AS160 contributes to glucocorticoid-mediated inhibition of glucose uptake in human and murine adipocytes. Mol. Cell. Endocrinol. 2009, 302:33-40.
30. Patil A.D., Freyer A.J., Eggleston D.S., Haltiwanger R.C., Bean M.F., Taylor P.B., Caranfa M.J., Breen A.L., Bartus H.R., Johnson R.K., Hertzberg R.P., Westley J.W. The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn. J. Med. Chem. 1993, 36:4131-4138.
31. Pessin J.E., Saltiel A.R. Signaling pathways in insulin action: molecular targets of insulin resistance. J. Clin. Invest. 2000, 106:165-169.
32. Prasad J., Shrivastava A., Khanna A.K., Bhatia G., Awasthi S.K., Narender T. Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum. Phytomedicine 2012, 19:1245-1249.
33. Reaven G.M. Pathophysiology of insulin resistance in human disease. Physiol. Rev. 1995, 75:473-486.
34. Sajan M.P., Bandyopadhyay G., Kanoh Y., Standaert M.L., Quon M.J., Reed B.C., Dikic I., Farese R.V. Sorbitol activates atypical protein kinase C and GLUT4 glucose transporter translocation/glucose transport through proline-rich tyrosine kinase-2, the extracellular signal-regulated kinase pathway and phospholipase D. Biochem. J. 2002, 362:665-674.
35. Sano H., Kane S., Sano E., Mîinea C.P., Asara J.M., Lane W.S., Garner C.W., Lienhard G.E. Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. J. Biol. Chem. 2003, 278:14599-14602.
36. Shang W., Yang Y., Zhou L., Jiang B., Jin H., Chen M. Ginsenoside Rb1 stimulates glucose uptake through insulin-like signaling pathway in 3T3-L1 adipocytes. J. Endocrinol. 2008, 198:561-569.
37. Smith A.G., Muscat G.E. Skeletal muscle and nuclear hormone receptors: implications for cardiovascular and metabolic disease. Int. J. Biochem. Cell Biol. 2005, 37:2047-2063.
38. Tamrakar A.K., Schertzer J.D., Chiu T.T., Foley K.P., Bilan P.J., Philpott D.J., Klip A. NOD2 activation induces muscle cell-autonomous innate immune responses and insulin resistance. Endocrinology 2010, 151:5624-5637.
39. Tamrakar A.K., Jaiswal N., Yadav P.P., Maurya R., Srivastava A.K. Pongamol from Pongamia pinnata stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells. Mol. Cell. Endocrinol. 2011, 339:98-104.
40. Tan M.J., Ye J.M., Turner N., Hohnen-Behrens C., Ke C.Q., Tang C.P., Chen T., Weiss H.C., Gesing E.R., Rowland A., James D.E., Ye Y. Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway. Chem. Biol. 2008, 15:263-273.
41. Taniguchi C.M., Emanuelli B., Kahn C.R. Critical nodes in insulin signaling pathways: insight into insulin action. Nat. Rev. Mol. Cell. Biol. 2006, 7:85-96.
42. Tsai S.C., Liang Y.H., Chiang J.H., Liu F.C., Lin W.H., Chang S.J., Lin W.Y., Wu C.H., Weng J.R. Anti-inflammatory effects of Calophyllum inophyllum L. in RAW264.7 cells. Oncol. Rep. 2012, 28:1096-1102.
43. Ueyama A., Yaworsky K.L., Wang Q., Ebina Y., Klip A. GLUT-4myc ectopic expression in L6 myoblasts generates a GLUT-4-specific pool conferring insulin sensitivity. Am. J. Physiol. 1999, 277:E572-E578.
44. Watson R.T., Pessin J.E. Bridging the GAP between insulin signaling and GLUT4 translocation. Trends. Biochem. Sci. 2006, 31:215-222.
45. Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., Wu M., Ventre J., Doebber T., Fujii N., Musi N., Hirshman M.F., Goodyear L.J., Moller D.E. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 2001, 108:1167-1174.