-
1
-
-
84965113064
-
7Q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages
-
Adamo, A., Atashpaz, S., Germain, P.-L., Zanella, M., D'Agostino, G., Albertin, V., Chenoweth, J., Micale, L., Fusco, C., Unger, C., Augello, B., Palumbo, O., Hamilton, B., Carella, M., Donti, E., Pruneri, G., Selicorni, A., Biamino, E., Prontera, P., McKay, R., Merla, G., Testa, G., 7Q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages. Nat. Genet. 47 (2014), 132–141, 10.1038/ng.3169.
-
(2014)
Nat. Genet.
, vol.47
, pp. 132-141
-
-
Adamo, A.1
Atashpaz, S.2
Germain, P.-L.3
Zanella, M.4
D'Agostino, G.5
Albertin, V.6
Chenoweth, J.7
Micale, L.8
Fusco, C.9
Unger, C.10
Augello, B.11
Palumbo, O.12
Hamilton, B.13
Carella, M.14
Donti, E.15
Pruneri, G.16
Selicorni, A.17
Biamino, E.18
Prontera, P.19
McKay, R.20
Merla, G.21
Testa, G.22
more..
-
2
-
-
84951908046
-
Common polygenic variation and risk for childhood-onset schizophrenia
-
Ahn, K., An, S.S., Shugart, Y.Y., Rapoport, J.L., Common polygenic variation and risk for childhood-onset schizophrenia. Mol. Psychiatry, 2014, 1–3, 10.1038/mp.2014.158.
-
(2014)
Mol. Psychiatry
, pp. 1-3
-
-
Ahn, K.1
An, S.S.2
Shugart, Y.Y.3
Rapoport, J.L.4
-
3
-
-
84899478669
-
High rate of disease-related copy number variations in childhood onset schizophrenia
-
Ahn, K., Gotay, N., Andersen, T.M., Anvari, a a, Gochman, P., Lee, Y., Sanders, S., Guha, S., Darvasi, A., Glessner, J.T., Hakonarson, H., Lencz, T., State, M.W., Shugart, Y.Y., Rapoport, J.L., High rate of disease-related copy number variations in childhood onset schizophrenia. Mol. Psychiatry 19 (2014), 568–572, 10.1038/mp.2013.59.
-
(2014)
Mol. Psychiatry
, vol.19
, pp. 568-572
-
-
Ahn, K.1
Gotay, N.2
Andersen, T.M.3
Anvari, A.A.4
Gochman, P.5
Lee, Y.6
Sanders, S.7
Guha, S.8
Darvasi, A.9
Glessner, J.T.10
Hakonarson, H.11
Lencz, T.12
State, M.W.13
Shugart, Y.Y.14
Rapoport, J.L.15
-
4
-
-
62649112887
-
Endophenotypes in schizophrenia: a selective review
-
Allen, A.J., Griss, M.E., Folley, B.S., Hawkins, K. a, Pearlson, G.D., Endophenotypes in schizophrenia: a selective review. Schizophr. Res. 109 (2009), 24–37, 10.1016/j.schres.2009.01.016.
-
(2009)
Schizophr. Res.
, vol.109
, pp. 24-37
-
-
Allen, A.J.1
Griss, M.E.2
Folley, B.S.3
Hawkins, K.A.4
Pearlson, G.D.5
-
5
-
-
80053143413
-
Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model
-
Ananiev, G., Williams, E.C., Li, H., Chang, Q., Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model. PLoS One, 6, 2011, e25255, 10.1371/journal.pone.0025255.
-
(2011)
PLoS One
, vol.6
, pp. e25255
-
-
Ananiev, G.1
Williams, E.C.2
Li, H.3
Chang, Q.4
-
6
-
-
0033861549
-
Human and mouse gene structure: comparative analysis and application to exon prediction
-
Batzoglou, S., Human and mouse gene structure: comparative analysis and application to exon prediction. Genome Res. 10 (2000), 950–958, 10.1101/gr.10.7.950.
-
(2000)
Genome Res.
, vol.10
, pp. 950-958
-
-
Batzoglou, S.1
-
7
-
-
33845870419
-
Deconstructing Schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder
-
Braff, D.L., Freedman, R., Schork, N.J., Gottesman, I.I., Deconstructing Schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr. Bull. 33 (2006), 21–32, 10.1093/schbul/sbl049.
-
(2006)
Schizophr. Bull.
, vol.33
, pp. 21-32
-
-
Braff, D.L.1
Freedman, R.2
Schork, N.J.3
Gottesman, I.I.4
-
8
-
-
84924721164
-
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
-
Brennand, K., Savas, J.N., Kim, Y., Tran, N., Simone, a, Hashimoto-Torii, K., Beaumont, K.G., Kim, H.J., Topol, a, Ladran, I., Abdelrahim, M., Matikainen-Ankney, B., Chao, S.-H., Mrksich, M., Rakic, P., Fang, G., Zhang, B., Yates, J.R., Gage, F.H., Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. Mol. Psychiatry 20 (2014), 1–8, 10.1038/mp.2014.22.
-
(2014)
Mol. Psychiatry
, vol.20
, pp. 1-8
-
-
Brennand, K.1
Savas, J.N.2
Kim, Y.3
Tran, N.4
Simone, A.5
Hashimoto-Torii, K.6
Beaumont, K.G.7
Kim, H.J.8
Topol, A.9
Ladran, I.10
Abdelrahim, M.11
Matikainen-Ankney, B.12
Chao, S.-H.13
Mrksich, M.14
Rakic, P.15
Fang, G.16
Zhang, B.17
Yates, J.R.18
Gage, F.H.19
-
9
-
-
84901313139
-
Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cells
-
Brennand, K.J., Landek-Salgado, M.A., Sawa, A., Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cells. Biol. Psychiatry 75 (2014), 936–944, 10.1016/j.biopsych.2013.10.025.
-
(2014)
Biol. Psychiatry
, vol.75
, pp. 936-944
-
-
Brennand, K.J.1
Landek-Salgado, M.A.2
Sawa, A.3
-
10
-
-
79955884485
-
Modelling schizophrenia using human induced pluripotent stem cells
-
Brennand, K.J., Simone, A., Jou, J., Gelboin-Burkhart, C., Tran, N., Sangar, S., Li, Y., Mu, Y., Chen, G., Yu, D., McCarthy, S., Sebat, J., Gage, F.H., Modelling schizophrenia using human induced pluripotent stem cells. Nature 473 (2011), 221–225, 10.1038/nature09915.
-
(2011)
Nature
, vol.473
, pp. 221-225
-
-
Brennand, K.J.1
Simone, A.2
Jou, J.3
Gelboin-Burkhart, C.4
Tran, N.5
Sangar, S.6
Li, Y.7
Mu, Y.8
Chen, G.9
Yu, D.10
McCarthy, S.11
Sebat, J.12
Gage, F.H.13
-
11
-
-
84922359495
-
Genetic studies of schizophrenia: an update
-
Chen, J., Cao, F., Liu, L., Wang, L., Chen, X., Genetic studies of schizophrenia: an update. Neurosci. Bull. 31 (2015), 87–98, 10.1007/s12264-014-1494-4.
-
(2015)
Neurosci. Bull.
, vol.31
, pp. 87-98
-
-
Chen, J.1
Cao, F.2
Liu, L.3
Wang, L.4
Chen, X.5
-
12
-
-
84876374695
-
Molecular analysis of a deletion hotspot in the NRXN1 region reveals the involvement of short inverted repeats in deletion CNVs
-
Chen, X., Shen, Y., Zhang, F., Chiang, C., Pillalamarri, V., Blumenthal, I., Talkowski, M., Wu, B.L., Gusella, J.F., Molecular analysis of a deletion hotspot in the NRXN1 region reveals the involvement of short inverted repeats in deletion CNVs. Am. J. Hum. Genet. 92 (2013), 375–386, 10.1016/j.ajhg.2013.02.006.
-
(2013)
Am. J. Hum. Genet.
, vol.92
, pp. 375-386
-
-
Chen, X.1
Shen, Y.2
Zhang, F.3
Chiang, C.4
Pillalamarri, V.5
Blumenthal, I.6
Talkowski, M.7
Wu, B.L.8
Gusella, J.F.9
-
13
-
-
79953048441
-
Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation
-
Chiang, C.-H., Su, Y., Wen, Z., Yoritomo, N., Ross, C.A., Margolis, R.L., Song, H., Ming, G., Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation. Mol. Psychiatry 16 (2011), 358–360, 10.1038/mp.2011.13.
-
(2011)
Mol. Psychiatry
, vol.16
, pp. 358-360
-
-
Chiang, C.-H.1
Su, Y.2
Wen, Z.3
Yoritomo, N.4
Ross, C.A.5
Margolis, R.L.6
Song, H.7
Ming, G.8
-
14
-
-
84901853724
-
Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models
-
(80-.)
-
Chun, S., Westmoreland, J.J., Bayazitov, I.T., Eddins, D., Pani, A.K., Smeyne, R.J., Yu, J., Blundon, J.A., Zakharenko, S.S., Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models. Science 344 (2014), 1178–1182, 10.1126/science.1253895 (80-.).
-
(2014)
Science
, vol.344
, pp. 1178-1182
-
-
Chun, S.1
Westmoreland, J.J.2
Bayazitov, I.T.3
Eddins, D.4
Pani, A.K.5
Smeyne, R.J.6
Yu, J.7
Blundon, J.A.8
Zakharenko, S.S.9
-
15
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L., Ran, F.A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P.D., Wu, X., Jiang, W., Marraffini, L.A., Zhang, F., Multiplex genome engineering using CRISPR/Cas systems. Science 80:339 (2013), 819–823, 10.1126/science.1231143.
-
(2013)
Science
, vol.80
, Issue.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
Zhang, F.11
-
16
-
-
79959725029
-
Variation in genome-wide mutation rates within and between human families
-
Conrad, D.F., Keebler, J.E.M., DePristo, M.A., Lindsay, S.J., Zhang, Y., Casals, F., Idaghdour, Y., Hartl, C.L., Torroja, C., Garimella, K.V., Zilversmit, M., Cartwright, R., Rouleau, G.A., Daly, M., Stone, E.A., Hurles, M.E., Awadalla, P., Variation in genome-wide mutation rates within and between human families. Nat. Genet. 43 (2011), 712–714, 10.1038/ng.862.
-
(2011)
Nat. Genet.
, vol.43
, pp. 712-714
-
-
Conrad, D.F.1
Keebler, J.E.M.2
DePristo, M.A.3
Lindsay, S.J.4
Zhang, Y.5
Casals, F.6
Idaghdour, Y.7
Hartl, C.L.8
Torroja, C.9
Garimella, K.V.10
Zilversmit, M.11
Cartwright, R.12
Rouleau, G.A.13
Daly, M.14
Stone, E.A.15
Hurles, M.E.16
Awadalla, P.17
-
17
-
-
84922639322
-
hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice
-
Cunningham, M., Cho, J.-H., Leung, A., Savvidis, G., Ahn, S., Moon, M., Lee, P.K.J., Han, J.J., Azimi, N., Kim, K.-S., Bolshakov, V.Y., Chung, S., hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice. Cell Stem Cell 15 (2014), 559–573, 10.1016/j.stem.2014.10.006.
-
(2014)
Cell Stem Cell
, vol.15
, pp. 559-573
-
-
Cunningham, M.1
Cho, J.-H.2
Leung, A.3
Savvidis, G.4
Ahn, S.5
Moon, M.6
Lee, P.K.J.7
Han, J.J.8
Azimi, N.9
Kim, K.-S.10
Bolshakov, V.Y.11
Chung, S.12
-
18
-
-
84893813097
-
Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function
-
Demjaha, A., Egerton, A., Murray, R.M., Kapur, S., Howes, O.D., Stone, J.M., McGuire, P.K., Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function. Biol. Psychiatry 75 (2014), e11–e13, 10.1016/j.biopsych.2013.06.011.
-
(2014)
Biol. Psychiatry
, vol.75
, pp. e11-e13
-
-
Demjaha, A.1
Egerton, A.2
Murray, R.M.3
Kapur, S.4
Howes, O.D.5
Stone, J.M.6
McGuire, P.K.7
-
19
-
-
46249131138
-
NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II trials
-
Diener, H.C., Lees, K.R., Lyden, P., Grotta, J., Davalos, A., Davis, S.M., Shuaib, A., Ashwood, T., Wasiewski, W., Alderfer, V., Hårdemark, H.G., Rodichok, L., NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II trials. Stroke 39 (2008), 1751–1758, 10.1161/STROKEAHA.107.503334.
-
(2008)
Stroke
, vol.39
, pp. 1751-1758
-
-
Diener, H.C.1
Lees, K.R.2
Lyden, P.3
Grotta, J.4
Davalos, A.5
Davis, S.M.6
Shuaib, A.7
Ashwood, T.8
Wasiewski, W.9
Alderfer, V.10
Hårdemark, H.G.11
Rodichok, L.12
-
20
-
-
79953306632
-
The 22q11.2 microdeletion: fifteen years of insights into the genetic and neural complexity of psychiatric disorders
-
Drew, L.J., Crabtree, G.W., Markx, S., Stark, K.L., Chaverneff, F., Xu, B., Mukai, J., Fenelon, K., Hsu, P., Gogos, J.A., Karayiorgou, M., The 22q11.2 microdeletion: fifteen years of insights into the genetic and neural complexity of psychiatric disorders. Int. J. Dev. Neurosci. 29 (2011), 259–281, 10.1016/j.ijdevneu.2010.09.007.
-
(2011)
Int. J. Dev. Neurosci.
, vol.29
, pp. 259-281
-
-
Drew, L.J.1
Crabtree, G.W.2
Markx, S.3
Stark, K.L.4
Chaverneff, F.5
Xu, B.6
Mukai, J.7
Fenelon, K.8
Hsu, P.9
Gogos, J.A.10
Karayiorgou, M.11
-
21
-
-
84930370590
-
Phenotypic characterization of nonsocial behavioral impairment in neurexin 1α knockout rats
-
Esclassan, F., Francois, J., Phillips, K.G., Loomis, S., Gilmour, G., Phenotypic characterization of nonsocial behavioral impairment in neurexin 1α knockout rats. Behav. Neurosci. 129 (2015), 74–85, 10.1037/bne0000024.
-
(2015)
Behav. Neurosci.
, vol.129
, pp. 74-85
-
-
Esclassan, F.1
Francois, J.2
Phillips, K.G.3
Loomis, S.4
Gilmour, G.5
-
22
-
-
84873282055
-
Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo
-
Espuny-Camacho, I., Michelsen, K. a, Gall, D., Linaro, D., Hasche, A., Bonnefont, J., Bali, C., Orduz, D., Bilheu, A., Herpoel, A., Lambert, N., Gaspard, N., Péron, S., Schiffmann, S.N., Giugliano, M., Gaillard, A., Vanderhaeghen, P., Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo. Neuron 77 (2013), 440–456, 10.1016/j.neuron.2012.12.011.
-
(2013)
Neuron
, vol.77
, pp. 440-456
-
-
Espuny-Camacho, I.1
Michelsen, K.A.2
Gall, D.3
Linaro, D.4
Hasche, A.5
Bonnefont, J.6
Bali, C.7
Orduz, D.8
Bilheu, A.9
Herpoel, A.10
Lambert, N.11
Gaspard, N.12
Péron, S.13
Schiffmann, S.N.14
Giugliano, M.15
Gaillard, A.16
Vanderhaeghen, P.17
-
23
-
-
70449686185
-
Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
-
Etherton, M.R., Blaiss, C. a, Powell, C.M., Südhof, T.C., Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 17998–18003, 10.1073/pnas.0910297106.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 17998-18003
-
-
Etherton, M.R.1
Blaiss, C.A.2
Powell, C.M.3
Südhof, T.C.4
-
24
-
-
84903134898
-
A mouse model that recapitulates cardinal features of the 15q13.3 microdeletion syndrome including schizophrenia- and epilepsy-related alterations
-
Fejgin, K., Nielsen, J., Birknow, M.R., Bastlund, J.F., Nielsen, V., Lauridsen, J.B., Stefansson, H., Steinberg, S., Sorensen, H.B.D., Mortensen, T.E., Larsen, P.H., Klewe, I.V., Rasmussen, S.V., Stefansson, K., Werge, T.M., Kallunki, P., Christensen, K.V., Didriksen, M., A mouse model that recapitulates cardinal features of the 15q13.3 microdeletion syndrome including schizophrenia- and epilepsy-related alterations. Biol. Psychiatry 76 (2014), 128–137, 10.1016/j.biopsych.2013.08.014.
-
(2014)
Biol. Psychiatry
, vol.76
, pp. 128-137
-
-
Fejgin, K.1
Nielsen, J.2
Birknow, M.R.3
Bastlund, J.F.4
Nielsen, V.5
Lauridsen, J.B.6
Stefansson, H.7
Steinberg, S.8
Sorensen, H.B.D.9
Mortensen, T.E.10
Larsen, P.H.11
Klewe, I.V.12
Rasmussen, S.V.13
Stefansson, K.14
Werge, T.M.15
Kallunki, P.16
Christensen, K.V.17
Didriksen, M.18
-
25
-
-
84890053248
-
MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review
-
Forstner, A.J., Degenhardt, F., Schratt, G., Nöthen, M.M., MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review. Front. Mol. Neurosci, 6, 2013, 47, 10.3389/fnmol.2013.00047.
-
(2013)
Front. Mol. Neurosci
, vol.6
, pp. 47
-
-
Forstner, A.J.1
Degenhardt, F.2
Schratt, G.3
Nöthen, M.M.4
-
26
-
-
15144349175
-
A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region
-
Galili, N., Baldwin, H.S., Lund, J., Reeves, R., Gong, W., Wang, Z., Roe, B. a, Emanuel, B.S., Nayak, S., Mickanin, C., Budarf, M.L., Buck, C., A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region. Genome Res. 7 (1997), 17–26.
-
(1997)
Genome Res.
, vol.7
, pp. 17-26
-
-
Galili, N.1
Baldwin, H.S.2
Lund, J.3
Reeves, R.4
Gong, W.5
Wang, Z.6
Roe, B.A.7
Emanuel, B.S.8
Nayak, S.9
Mickanin, C.10
Budarf, M.L.11
Buck, C.12
-
27
-
-
84937637283
-
MicroRNA and posttranscriptional dysregulation in psychiatry
-
Geaghan, M., Cairns, M.J., MicroRNA and posttranscriptional dysregulation in psychiatry. Biol. Psychiatry, 2014, 1–9, 10.1016/j.biopsych.2014.12.009.
-
(2014)
Biol. Psychiatry
, pp. 1-9
-
-
Geaghan, M.1
Cairns, M.J.2
-
28
-
-
84906923071
-
Gene expression analysis of human induced pluripotent stem cell-derived neurons carrying copy number variants of chromosome 15q11-q13.1
-
Germain, N.D., Chen, P.-F., Plocik, A.M., Glatt-Deeley, H., Brown, J., Fink, J.J., Bolduc, K.a, Robinson, T.M., Levine, E.S., Reiter, L.T., Graveley, B.R., Lalande, M., Chamberlain, S.J., Gene expression analysis of human induced pluripotent stem cell-derived neurons carrying copy number variants of chromosome 15q11-q13.1. Mol. Autism, 5, 2014, 44, 10.1186/2040-2392-5-44.
-
(2014)
Mol. Autism
, vol.5
, pp. 44
-
-
Germain, N.D.1
Chen, P.-F.2
Plocik, A.M.3
Glatt-Deeley, H.4
Brown, J.5
Fink, J.J.6
Bolduc, K.A.7
Robinson, T.M.8
Levine, E.S.9
Reiter, L.T.10
Graveley, B.R.11
Lalande, M.12
Chamberlain, S.J.13
-
29
-
-
84879522237
-
Altered social behaviours in neurexin 1α knockout mice resemble core symptoms in neurodevelopmental disorders
-
Grayton, H.M., Missler, M., Collier, D.A., Fernandes, C., Altered social behaviours in neurexin 1α knockout mice resemble core symptoms in neurodevelopmental disorders. PLoS One, 8, 2013, e67114, 10.1371/journal.pone.0067114.
-
(2013)
PLoS One
, vol.8
, pp. e67114
-
-
Grayton, H.M.1
Missler, M.2
Collier, D.A.3
Fernandes, C.4
-
30
-
-
82455199147
-
Induced pluripotent stem cells — opportunities for disease modelling and drug discovery
-
Grskovic, M., Javaherian, A., Strulovici, B., Daley, G.Q., Induced pluripotent stem cells — opportunities for disease modelling and drug discovery. Nat. Rev. Drug Discov., 2011, 10, 10.1038/nrd3577.
-
(2011)
Nat. Rev. Drug Discov.
, pp. 10
-
-
Grskovic, M.1
Javaherian, A.2
Strulovici, B.3
Daley, G.Q.4
-
31
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han, J., The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18 (2004), 3016–3027, 10.1101/gad.1262504.
-
(2004)
Genes Dev.
, vol.18
, pp. 3016-3027
-
-
Han, J.1
-
33
-
-
84888293604
-
Copy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders
-
Hiroi, N., Takahashi, T., Hishimoto, A., Izumi, T., Boku, S., Hiramoto, T., Copy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders. Mol. Psychiatry 18 (2013), 1153–1165, 10.1038/mp.2013.92.
-
(2013)
Mol. Psychiatry
, vol.18
, pp. 1153-1165
-
-
Hiroi, N.1
Takahashi, T.2
Hishimoto, A.3
Izumi, T.4
Boku, S.5
Hiramoto, T.6
-
34
-
-
84981734325
-
From “directed differentiatio” to “neuronal induction”: modeling neuropsychiatric disease
-
Ho, S., Topol, A., Brennand, K.J., From “directed differentiatio” to “neuronal induction”: modeling neuropsychiatric disease. Biomark. Insights, 10, 2015, 31, 10.4137/BMI.S20066.
-
(2015)
Biomark. Insights
, vol.10
, pp. 31
-
-
Ho, S.1
Topol, A.2
Brennand, K.J.3
-
35
-
-
84908030684
-
Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons
-
Hook, V., Brennand, K.J., Kim, Y., Toneff, T., Funkelstein, L., Lee, K.C., Ziegler, M., Gage, F.H., Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons. Stem Cell Reports 3 (2014), 531–538, 10.1016/j.stemcr.2014.08.001.
-
(2014)
Stem Cell Reports
, vol.3
, pp. 531-538
-
-
Hook, V.1
Brennand, K.J.2
Kim, Y.3
Toneff, T.4
Funkelstein, L.5
Lee, K.C.6
Ziegler, M.7
Gage, F.H.8
-
36
-
-
80054754473
-
Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism
-
Horev, G., Ellegood, J., Lerch, J.P., Son, Y.-E.E., Muthuswamy, L., Vogel, H., Krieger, A.M., Buja, A., Henkelman, R.M., Wigler, M., Mills, A.A., Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proc. Natl. Acad. Sci. 108 (2011), 17076–17081, 10.1073/pnas.1114042108.
-
(2011)
Proc. Natl. Acad. Sci.
, vol.108
, pp. 17076-17081
-
-
Horev, G.1
Ellegood, J.2
Lerch, J.P.3
Son, Y.-E.E.4
Muthuswamy, L.5
Vogel, H.6
Krieger, A.M.7
Buja, A.8
Henkelman, R.M.9
Wigler, M.10
Mills, A.A.11
-
37
-
-
84902096048
-
Development and applications of CRISPR-Cas9 for genome engineering
-
Hsu, P.D., Lander, E.S., Zhang, F., Development and applications of CRISPR-Cas9 for genome engineering. Cell 157 (2014), 1262–1278, 10.1016/j.cell.2014.05.010.
-
(2014)
Cell
, vol.157
, pp. 1262-1278
-
-
Hsu, P.D.1
Lander, E.S.2
Zhang, F.3
-
38
-
-
51649107017
-
Rare chromosomal deletions and duplications increase risk of schizophrenia
-
International, T., Consortium, S., Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 455 (2008), 237–241, 10.1038/nature07239.
-
(2008)
Nature
, vol.455
, pp. 237-241
-
-
International, T.1
Consortium, S.2
-
39
-
-
84874608929
-
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
-
Jiang, W., Bikard, D., Cox, D., Zhang, F., Marraffini, L., RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat. Biotechnol. 31 (2013), 233–239, 10.1038/nbt.2508.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 233-239
-
-
Jiang, W.1
Bikard, D.2
Cox, D.3
Zhang, F.4
Marraffini, L.5
-
40
-
-
65649112466
-
Functional and evolutionary insights into human brain development through global transcriptome analysis
-
Johnson, M.B., Kawasawa, Y.I., Mason, C.E., Krsnik, Ž., Coppola, G., Bogdanović, D., Geschwind, D.H., Mane, S.M., State, M.W., Šestan, N., Functional and evolutionary insights into human brain development through global transcriptome analysis. Neuron 62 (2009), 494–509, 10.1016/j.neuron.2009.03.027.
-
(2009)
Neuron
, vol.62
, pp. 494-509
-
-
Johnson, M.B.1
Kawasawa, Y.I.2
Mason, C.E.3
Krsnik, Ž.4
Coppola, G.5
Bogdanović, D.6
Geschwind, D.H.7
Mane, S.M.8
State, M.W.9
Šestan, N.10
-
41
-
-
84929945448
-
Prader–Willi, Angelman, and 15q11–q13 duplication syndromes
-
Kalsner, L., Chamberlain, S.J., Prader–Willi, Angelman, and 15q11–q13 duplication syndromes. Pediatr. Clin. North Am. 62 (2015), 587–606.
-
(2015)
Pediatr. Clin. North Am.
, vol.62
, pp. 587-606
-
-
Kalsner, L.1
Chamberlain, S.J.2
-
42
-
-
77952738956
-
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia
-
Karayiorgou, M., Simon, T.J., Gogos, J. a, 22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nat. Rev. Neurosci. 11 (2010), 402–416, 10.1038/nrn2841.
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 402-416
-
-
Karayiorgou, M.1
Simon, T.J.2
Gogos, J.A.3
-
43
-
-
66249116695
-
Modeling cognitive endophenotypes of schizophrenia in mice
-
Kellendonk, C., Simpson, E.H., Kandel, E.R., Modeling cognitive endophenotypes of schizophrenia in mice. Trends Neurosci. 32 (2009), 347–358, 10.1016/j.tins.2009.02.003.
-
(2009)
Trends Neurosci.
, vol.32
, pp. 347-358
-
-
Kellendonk, C.1
Simpson, E.H.2
Kandel, E.R.3
-
44
-
-
64549147485
-
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia
-
Kirov, G., Grozeva, D., Norton, N., Ivanov, D., Mantripragada, K.K., Holmans, P., Craddock, N., Owen, M.J., O'Donovan, M.C., Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Hum. Mol. Genet. 18 (2009), 1497–1503, 10.1093/hmg/ddp043.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1497-1503
-
-
Kirov, G.1
Grozeva, D.2
Norton, N.3
Ivanov, D.4
Mantripragada, K.K.5
Holmans, P.6
Craddock, N.7
Owen, M.J.8
O'Donovan, M.C.9
-
45
-
-
84856225986
-
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
-
Kirov, G., Pocklington, A., Holmans, P.A., Ivanov, D.K., Ikeda, M., Ruderfer, D., Moran, J., Chambert, K., Toncheva, D., Georgieva, L., Grozeva, D.V., Fjodorova, M., Wollerton, R.L., Rees, E., Nikolova, I., van de Lagemaat, L.N., Bayés, À., Fernandez, E., Olason, P.I., Böttcher, Y., Komiyama, N.H., Collins, M.O., Choudhary, J., Stefansson, K., Stefansson, H., Grant, S.G.N., Purcell, S., Sklar, P., O'Donovan, M.C., Owen, M.J., De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol. Psychiatry, 2011, 142–153, 10.1038/mp.2011.154.
-
(2011)
Mol. Psychiatry
, pp. 142-153
-
-
Kirov, G.1
Pocklington, A.2
Holmans, P.A.3
Ivanov, D.K.4
Ikeda, M.5
Ruderfer, D.6
Moran, J.7
Chambert, K.8
Toncheva, D.9
Georgieva, L.10
Grozeva, D.V.11
Fjodorova, M.12
Wollerton, R.L.13
Rees, E.14
Nikolova, I.15
van de Lagemaat, L.N.16
Bayés, À.17
Fernandez, E.18
Olason, P.I.19
Böttcher, Y.20
Komiyama, N.H.21
Collins, M.O.22
Choudhary, J.23
Stefansson, K.24
Stefansson, H.25
Grant, S.G.N.26
Purcell, S.27
Sklar, P.28
O'Donovan, M.C.29
Owen, M.J.30
more..
-
46
-
-
84893491567
-
The Penetrance of copy number variations for schizophrenia and developmental delay
-
Kirov, G., Rees, E., Walters, J.T.R., Escott-Price, V., Georgieva, L., Richards, A.L., Chambert, K.D., Davies, G., Legge, S.E., Moran, J.L., McCarroll, S.A., O'Donovan, M.C., Owen, M.J., The Penetrance of copy number variations for schizophrenia and developmental delay. Biol. Psychiatry 75 (2014), 378–385, 10.1016/j.biopsych.2013.07.022.
-
(2014)
Biol. Psychiatry
, vol.75
, pp. 378-385
-
-
Kirov, G.1
Rees, E.2
Walters, J.T.R.3
Escott-Price, V.4
Georgieva, L.5
Richards, A.L.6
Chambert, K.D.7
Davies, G.8
Legge, S.E.9
Moran, J.L.10
McCarroll, S.A.11
O'Donovan, M.C.12
Owen, M.J.13
-
47
-
-
84897502442
-
Concise review: drug discovery in the age of the induced pluripotent stem cell
-
Ko, H.C., Gelb, B.D., Concise review: drug discovery in the age of the induced pluripotent stem cell. Stem Cells Trans. Med. 3 (2014), 500–509, 10.5966/sctm.2013-0162.
-
(2014)
Stem Cells Trans. Med.
, vol.3
, pp. 500-509
-
-
Ko, H.C.1
Gelb, B.D.2
-
48
-
-
84923096541
-
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
-
Konermann, S., Brigham, M.D., Trevino, A.E., Joung, J., Abudayyeh, O.O., Barcena, C., Hsu, P.D., Habib, N., Gootenberg, J.S., Nishimasu, H., Nureki, O., Zhang, F., Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature 517 (2014), 583–588, 10.1038/nature14136.
-
(2014)
Nature
, vol.517
, pp. 583-588
-
-
Konermann, S.1
Brigham, M.D.2
Trevino, A.E.3
Joung, J.4
Abudayyeh, O.O.5
Barcena, C.6
Hsu, P.D.7
Habib, N.8
Gootenberg, J.S.9
Nishimasu, H.10
Nureki, O.11
Zhang, F.12
-
49
-
-
84355166561
-
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
-
Kriks, S., Shim, J.-W., Piao, J., Ganat, Y.M., Wakeman, D.R., Xie, Z., Carrillo-Reid, L., Auyeung, G., Antonacci, C., Buch, A., Yang, L., Beal, M.F., Surmeier, D.J., Kordower, J.H., Tabar, V., Studer, L., Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 480 (2011), 547–551, 10.1038/nature10648.
-
(2011)
Nature
, vol.480
, pp. 547-551
-
-
Kriks, S.1
Shim, J.-W.2
Piao, J.3
Ganat, Y.M.4
Wakeman, D.R.5
Xie, Z.6
Carrillo-Reid, L.7
Auyeung, G.8
Antonacci, C.9
Buch, A.10
Yang, L.11
Beal, M.F.12
Surmeier, D.J.13
Kordower, J.H.14
Tabar, V.15
Studer, L.16
-
50
-
-
84856878562
-
Sex-dependent novelty response in neurexin-1?? mutant mice
-
Laarakker, M.C., Reinders, N.R., Bruining, H., Ophoff, R. a, Kas, M.J.H., Sex-dependent novelty response in neurexin-1?? mutant mice. PLoS One 7 (2012), 3–8, 10.1371/journal.pone.0031503.
-
(2012)
PLoS One
, vol.7
, pp. 3-8
-
-
Laarakker, M.C.1
Reinders, N.R.2
Bruining, H.3
Ophoff, R.A.4
Kas, M.J.H.5
-
51
-
-
84878641770
-
MeCP2 Regulates the Synaptic Expression of a Dysbindin-BLOC-1 Network Component in Mouse Brain and Human Induced Pluripotent Stem Cell-Derived Neurons
-
Larimore, J., Ryder, P.V, Kim, K.-Y., Ambrose, L.A., Chapleau, C., Calfa, G., Gross, C., Bassell, G.J., Pozzo-Miller, L., Smith, Y., Talbot, K., Park, I.-H., Faundez, V., MeCP2 Regulates the Synaptic Expression of a Dysbindin-BLOC-1 Network Component in Mouse Brain and Human Induced Pluripotent Stem Cell-Derived Neurons. PLoS One, 8, 2013, e65069, 10.1371/journal.pone.0065069.
-
(2013)
PLoS One
, vol.8
, pp. e65069
-
-
Larimore, J.1
Ryder, P.V.2
Kim, K.-Y.3
Ambrose, L.A.4
Chapleau, C.5
Calfa, G.6
Gross, C.7
Bassell, G.J.8
Pozzo-Miller, L.9
Smith, Y.10
Talbot, K.11
Park, I.-H.12
Faundez, V.13
-
52
-
-
84886993480
-
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
-
Larson, M.H., Gilbert, L. a, Wang, X., Lim, W. a, Weissman, J.S., Qi, L.S., CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nat. Protoc. 8 (2013), 2180–2196, 10.1038/nprot.2013.132.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 2180-2196
-
-
Larson, M.H.1
Gilbert, L.A.2
Wang, X.3
Lim, W.A.4
Weissman, J.S.5
Qi, L.S.6
-
53
-
-
74849123669
-
Induced chromosome deletions cause hypersociability and other features of Williams–Beuren syndrome in mice
-
Li, H.H., Roy, M., Kuscuoglu, U., Spencer, C.M., Halm, B., Harrison, K.C., Bayle, J.H., Splendore, A., Ding, F., Meltzer, L. a, Wright, E., Paylor, R., Deisseroth, K., Francke, U., Induced chromosome deletions cause hypersociability and other features of Williams–Beuren syndrome in mice. EMBO Mol. Med. 1 (2009), 50–65, 10.1002/emmm.200900003.
-
(2009)
EMBO Mol. Med.
, vol.1
, pp. 50-65
-
-
Li, H.H.1
Roy, M.2
Kuscuoglu, U.3
Spencer, C.M.4
Halm, B.5
Harrison, K.C.6
Bayle, J.H.7
Splendore, A.8
Ding, F.9
Meltzer, L.A.10
Wright, E.11
Paylor, R.12
Deisseroth, K.13
Francke, U.14
-
54
-
-
84865064735
-
Signaling defects in iPSC-derived fragile X premutation neurons
-
Liu, J., Koscielska, K.a., Cao, Z., Hulsizer, S., Grace, N., Mitchell, G., Nacey, C., Githinji, J., McGee, J., Garcia-Arocena, D., Hagerman, R.J., Nolta, J., Pessah, I.N., Hagerman, P.J., Signaling defects in iPSC-derived fragile X premutation neurons. Hum. Mol. Genet. 21 (2012), 3795–3805, 10.1093/hmg/dds207.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 3795-3805
-
-
Liu, J.1
Koscielska, K.A.2
Cao, Z.3
Hulsizer, S.4
Grace, N.5
Mitchell, G.6
Nacey, C.7
Githinji, J.8
McGee, J.9
Garcia-Arocena, D.10
Hagerman, R.J.11
Nolta, J.12
Pessah, I.N.13
Hagerman, P.J.14
-
55
-
-
33749058857
-
Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrome
-
Long, J.M., LaPorte, P., Merscher, S., Funke, B., Saint-Jore, B., Puech, A., Kucherlapati, R., Morrow, B.E., Skoultchi, A.I., Wynshaw-Boris, A., Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrome. Neurogenetics 7 (2006), 247–257, 10.1007/s10048-006-0054-0.
-
(2006)
Neurogenetics
, vol.7
, pp. 247-257
-
-
Long, J.M.1
LaPorte, P.2
Merscher, S.3
Funke, B.4
Saint-Jore, B.5
Puech, A.6
Kucherlapati, R.7
Morrow, B.E.8
Skoultchi, A.I.9
Wynshaw-Boris, A.10
-
56
-
-
84884907424
-
CRISPR RNA–guided activation of endogenous human genes
-
Maeder, M.L., Linder, S.J., Cascio, V.M., Fu, Y., Ho, Q.H., Joung, J.K., CRISPR RNA–guided activation of endogenous human genes. Nat. Methods 10 (2013), 977–979, 10.1038/nmeth.2598.
-
(2013)
Nat. Methods
, vol.10
, pp. 977-979
-
-
Maeder, M.L.1
Linder, S.J.2
Cascio, V.M.3
Fu, Y.4
Ho, Q.H.5
Joung, J.K.6
-
57
-
-
84858434210
-
CNVs: Harbingers of a rare variant revolution in psychiatric genetics
-
Malhotra, D., Sebat, J., CNVs: Harbingers of a rare variant revolution in psychiatric genetics. Cell 148 (2012), 1223–1241, 10.1016/j.cell.2012.02.039.
-
(2012)
Cell
, vol.148
, pp. 1223-1241
-
-
Malhotra, D.1
Sebat, J.2
-
58
-
-
84864506775
-
Modeling human cortical development in vitro using induced pluripotent stem cells
-
Mariani, J., Simonini, M.V., Palejev, D., Tomasini, L., Coppola, G., Szekely, A.M., Horvath, T.L., Vaccarino, F.M., Modeling human cortical development in vitro using induced pluripotent stem cells. Proc. Natl. Acad. Sci. 109 (2012), 12770–12775, 10.1073/pnas.1202944109.
-
(2012)
Proc. Natl. Acad. Sci.
, vol.109
, pp. 12770-12775
-
-
Mariani, J.1
Simonini, M.V.2
Palejev, D.3
Tomasini, L.4
Coppola, G.5
Szekely, A.M.6
Horvath, T.L.7
Vaccarino, F.M.8
-
59
-
-
84877271854
-
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells
-
Maroof, A.M., Keros, S., Tyson, J.A., Ying, S.-W., Ganat, Y.M., Merkle, F.T., Liu, B., Goulburn, A., Stanley, E.G., Elefanty, A.G., Widmer, H.R., Eggan, K., Goldstein, P.A., Anderson, S.A., Studer, L., Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell 12 (2013), 559–572, 10.1016/j.stem.2013.04.008.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 559-572
-
-
Maroof, A.M.1
Keros, S.2
Tyson, J.A.3
Ying, S.-W.4
Ganat, Y.M.5
Merkle, F.T.6
Liu, B.7
Goulburn, A.8
Stanley, E.G.9
Elefanty, A.G.10
Widmer, H.R.11
Eggan, K.12
Goldstein, P.A.13
Anderson, S.A.14
Studer, L.15
-
60
-
-
70350626873
-
Microduplications of 16p11.2 are associated with schizophrenia
-
McCarthy, S.E., Makarov, V., Kirov, G., Addington, A.M., McClellan, J., Yoon, S., Perkins, D.O., Dickel, D.E., Kusenda, M., Krastoshevsky, O., Krause, V., Kumar, R. a, Grozeva, D., Malhotra, D., Walsh, T., Zackai, E.H., Kaplan, P., Ganesh, J., Krantz, I.D., Spinner, N.B., Roccanova, P., Bhandari, A., Pavon, K., Lakshmi, B., Leotta, A., Kendall, J., Lee, Y.-H., Vacic, V., Gary, S., Iakoucheva, L.M., Crow, T.J., Christian, S.L., Lieberman, J. a, Stroup, T.S., Lehtimäki, T., Puura, K., Haldeman-Englert, C., Pearl, J., Goodell, M., Willour, V.L., Derosse, P., Steele, J., Kassem, L., Wolff, J., Chitkara, N., McMahon, F.J., Malhotra, A.K., Potash, J.B., Schulze, T.G., Nöthen, M.M., Cichon, S., Rietschel, M., Leibenluft, E., Kustanovich, V., Lajonchere, C.M., Sutcliffe, J.S., Skuse, D., Gill, M., Gallagher, L., Mendell, N.R., Craddock, N., Owen, M.J., O'Donovan, M.C., Shaikh, T.H., Susser, E., Delisi, L.E., Sullivan, P.F., Deutsch, C.K., Rapoport, J., Levy, D.L., King, M.-C., Sebat, J., Microduplications of 16p11.2 are associated with schizophrenia. Nat. Genet. 41 (2009), 1223–1227, 10.1038/ng.474.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1223-1227
-
-
McCarthy, S.E.1
Makarov, V.2
Kirov, G.3
Addington, A.M.4
McClellan, J.5
Yoon, S.6
Perkins, D.O.7
Dickel, D.E.8
Kusenda, M.9
Krastoshevsky, O.10
Krause, V.11
Kumar, R.A.12
Grozeva, D.13
Malhotra, D.14
Walsh, T.15
Zackai, E.H.16
Kaplan, P.17
Ganesh, J.18
Krantz, I.D.19
Spinner, N.B.20
Roccanova, P.21
Bhandari, A.22
Pavon, K.23
Lakshmi, B.24
Leotta, A.25
Kendall, J.26
Lee, Y.-H.27
Vacic, V.28
Gary, S.29
Iakoucheva, L.M.30
Crow, T.J.31
Christian, S.L.32
Lieberman, J.A.33
Stroup, T.S.34
Lehtimäki, T.35
Puura, K.36
Haldeman-Englert, C.37
Pearl, J.38
Goodell, M.39
Willour, V.L.40
Derosse, P.41
Steele, J.42
Kassem, L.43
Wolff, J.44
Chitkara, N.45
McMahon, F.J.46
Malhotra, A.K.47
Potash, J.B.48
Schulze, T.G.49
Nöthen, M.M.50
Cichon, S.51
Rietschel, M.52
Leibenluft, E.53
Kustanovich, V.54
Lajonchere, C.M.55
Sutcliffe, J.S.56
Skuse, D.57
Gill, M.58
Gallagher, L.59
Mendell, N.R.60
Craddock, N.61
Owen, M.J.62
O'Donovan, M.C.63
Shaikh, T.H.64
Susser, E.65
Delisi, L.E.66
Sullivan, P.F.67
Deutsch, C.K.68
Rapoport, J.69
Levy, D.L.70
King, M.-C.71
Sebat, J.72
more..
-
61
-
-
84868592827
-
Cxcr4 regulation of interneuron migration is disrupted in 22q11.2 deletion syndrome
-
Meechan, D.W., Tucker, E.S., Maynard, T.M., LaMantia, A.-S., Cxcr4 regulation of interneuron migration is disrupted in 22q11.2 deletion syndrome. Proc. Natl. Acad. Sci. 109 (2012), 18601–18606, 10.1073/pnas.1211507109.
-
(2012)
Proc. Natl. Acad. Sci.
, vol.109
, pp. 18601-18606
-
-
Meechan, D.W.1
Tucker, E.S.2
Maynard, T.M.3
LaMantia, A.-S.4
-
62
-
-
70349492911
-
Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome
-
Meechan, D.W., Tucker, E.S., Maynard, T.M., LaMantia, A.-S., Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 16434–16445, 10.1073/pnas.0905696106.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 16434-16445
-
-
Meechan, D.W.1
Tucker, E.S.2
Maynard, T.M.3
LaMantia, A.-S.4
-
63
-
-
17744395906
-
TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome
-
Merscher, S., Funke, B., Epstein, J. a, Heyer, J., Puech, A., Lu, M.M., Xavier, R.J., Demay, M.B., Russell, R.G., Factor, S., Tokooya, K., Jore, B.S., Lopez, M., Pandita, R.K., Lia, M., Carrion, D., Xu, H., Schorle, H., Kobler, J.B., Scambler, P., Wynshaw-Boris, A., Skoultchi, A.I., Morrow, B.E., Kucherlapati, R., TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell 104 (2001), 619–629, 10.1016/S0092-8674(01)00247-1.
-
(2001)
Cell
, vol.104
, pp. 619-629
-
-
Merscher, S.1
Funke, B.2
Epstein, J.A.3
Heyer, J.4
Puech, A.5
Lu, M.M.6
Xavier, R.J.7
Demay, M.B.8
Russell, R.G.9
Factor, S.10
Tokooya, K.11
Jore, B.S.12
Lopez, M.13
Pandita, R.K.14
Lia, M.15
Carrion, D.16
Xu, H.17
Schorle, H.18
Kobler, J.B.19
Scambler, P.20
Wynshaw-Boris, A.21
Skoultchi, A.I.22
Morrow, B.E.23
Kucherlapati, R.24
more..
-
64
-
-
34447319080
-
An improved zinc-finger nuclease architecture for highly specific genome editing
-
Miller, J.C., Holmes, M.C., Wang, J., Guschin, D.Y., Lee, Y.-L., Rupniewski, I., Beausejour, C.M., Waite, A.J., Wang, N.S., Kim, K.A., Gregory, P.D., Pabo, C.O., Rebar, E.J., An improved zinc-finger nuclease architecture for highly specific genome editing. Nat. Biotechnol. 25 (2007), 778–785, 10.1038/nbt1319.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 778-785
-
-
Miller, J.C.1
Holmes, M.C.2
Wang, J.3
Guschin, D.Y.4
Lee, Y.-L.5
Rupniewski, I.6
Beausejour, C.M.7
Waite, A.J.8
Wang, N.S.9
Kim, K.A.10
Gregory, P.D.11
Pabo, C.O.12
Rebar, E.J.13
-
65
-
-
84975804424
-
Mapping copy number variation by population-scale genome sequencing
-
Mills, R.E., Walter, K., Stewart, C., Handsaker, R.E., Chen, K., Alkan, C., Abyzov, A., Yoon, S.C., Ye, K., Cheetham, R.K., et al. Mapping copy number variation by population-scale genome sequencing. Nature 470 (2011), 59–65, 10.1038/nature09708.Mapping.
-
(2011)
Nature
, vol.470
, pp. 59-65
-
-
Mills, R.E.1
Walter, K.2
Stewart, C.3
Handsaker, R.E.4
Chen, K.5
Alkan, C.6
Abyzov, A.7
Yoon, S.C.8
Ye, K.9
Cheetham, R.K.10
-
66
-
-
0031983653
-
Neurexins: Three genes and 1001 products
-
Missler, M., Südhof, T.C., Neurexins: Three genes and 1001 products. Trends Genet. 14 (1998), 20–26, 10.1016/S0168-9525(97)01324-3.
-
(1998)
Trends Genet.
, vol.14
, pp. 20-26
-
-
Missler, M.1
Südhof, T.C.2
-
67
-
-
0037774700
-
Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis
-
Missler, M., Zhang, W., Rohlmann, A., Kattenstroth, G., Hammer, R.E., Gottmann, K., Südhof, T.C., Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis. Nature 423 (2003), 939–948, 10.1038/nature01755.
-
(2003)
Nature
, vol.423
, pp. 939-948
-
-
Missler, M.1
Zhang, W.2
Rohlmann, A.3
Kattenstroth, G.4
Hammer, R.E.5
Gottmann, K.6
Südhof, T.C.7
-
68
-
-
54949150182
-
Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion
-
Mukai, J., Dhilla, A., Drew, L.J., Stark, K.L., Cao, L., MacDermott, A.B., Karayiorgou, M., Gogos, Ja, Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion. Nat. Neurosci. 11 (2008), 1302–1310, 10.1038/nn.2204.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 1302-1310
-
-
Mukai, J.1
Dhilla, A.2
Drew, L.J.3
Stark, K.L.4
Cao, L.5
MacDermott, A.B.6
Karayiorgou, M.7
Gogos, J.8
-
69
-
-
84929046357
-
Molecular Substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia
-
Mukai, J., Tamura, M., Fénelon, K., Rosen, A.M., Spellman, T.J., Kang, R., MacDermott, A.B., Karayiorgou, M., Gordon, J.A., Gogos, J.A., Molecular Substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia. Neuron, 2015, 680–695, 10.1016/j.neuron.2015.04.003.
-
(2015)
Neuron
, pp. 680-695
-
-
Mukai, J.1
Tamura, M.2
Fénelon, K.3
Rosen, A.M.4
Spellman, T.J.5
Kang, R.6
MacDermott, A.B.7
Karayiorgou, M.8
Gordon, J.A.9
Gogos, J.A.10
-
70
-
-
84937120796
-
Genetic analysis of schizophrenia and bipolar disorder reveals polygenicity but also suggests new directions for molecular interrogation
-
Neale, B.M., Sklar, P., Genetic analysis of schizophrenia and bipolar disorder reveals polygenicity but also suggests new directions for molecular interrogation. Curr. Opin. Neurobiol. 30 (2015), 131–138, 10.1016/j.conb.2014.12.001.
-
(2015)
Curr. Opin. Neurobiol.
, vol.30
, pp. 131-138
-
-
Neale, B.M.1
Sklar, P.2
-
71
-
-
84945952127
-
Human Inducible Pluripotent Stem Cells and Autism Spectrum Disorder: Emerging Technologies
-
n/a–n/a. doi:10.1002/aur.1570
-
Nestor, M.W., Phillips, A.W., Artimovich, E., Nestor, J.E., Hussman, J.P., Blatt, G.J., 2015. Human Inducible Pluripotent Stem Cells and Autism Spectrum Disorder: Emerging Technologies. Autism Res. n/a–n/a. doi:10.1002/aur.1570.
-
(2015)
Autism Res.
-
-
Nestor, M.W.1
Phillips, A.W.2
Artimovich, E.3
Nestor, J.E.4
Hussman, J.P.5
Blatt, G.J.6
-
72
-
-
84877301288
-
Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development
-
Nicholas, C.R., Chen, J., Tang, Y., Southwell, D.G., Chalmers, N., Vogt, D., Arnold, C.M., Chen, Y.-J.J., Stanley, E.G., Elefanty, A.G., Sasai, Y., Alvarez-Buylla, A., Rubenstein, J.L.R., Kriegstein, A.R., Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. Cell Stem Cell 12 (2013), 573–586, 10.1016/j.stem.2013.04.005.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 573-586
-
-
Nicholas, C.R.1
Chen, J.2
Tang, Y.3
Southwell, D.G.4
Chalmers, N.5
Vogt, D.6
Arnold, C.M.7
Chen, Y.-J.J.8
Stanley, E.G.9
Elefanty, A.G.10
Sasai, Y.11
Alvarez-Buylla, A.12
Rubenstein, J.L.R.13
Kriegstein, A.R.14
-
73
-
-
84944037049
-
Reversion of FMR1 methylation and silencing by editing the triplet repeats in fragile X iPSC-derived neurons
-
Park, C., Halevy, T., Lee, D.R., Sung, J.J., Lee, J.S., Yanuka, O., Benvenisty, N., Kim, D., Reversion of FMR1 methylation and silencing by editing the triplet repeats in fragile X iPSC-derived neurons. Cell Rep, 2015, 1–8, 10.1016/j.celrep.2015.08.084.
-
(2015)
Cell Rep
, pp. 1-8
-
-
Park, C.1
Halevy, T.2
Lee, D.R.3
Sung, J.J.4
Lee, J.S.5
Yanuka, O.6
Benvenisty, N.7
Kim, D.8
-
74
-
-
84934442315
-
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
-
Paşca, A.M., Sloan, S. a, Clarke, L.E., Tian, Y., Makinson, C.D., Huber, N., Kim, C.H., Park, J.-Y., O'Rourke, N. a, Nguyen, K.D., Smith, S.J., Huguenard, J.R., Geschwind, D.H., Barres, B. a, Paşca, S.P., Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nat. Methods, 2015, 12, 10.1038/nmeth.3415.
-
(2015)
Nat. Methods
, pp. 12
-
-
Paşca, A.M.1
Sloan, S.A.2
Clarke, L.E.3
Tian, Y.4
Makinson, C.D.5
Huber, N.6
Kim, C.H.7
Park, J.-Y.8
O'Rourke, N.A.9
Nguyen, K.D.10
Smith, S.J.11
Huguenard, J.R.12
Geschwind, D.H.13
Barres, B.A.14
Paşca, S.P.15
-
75
-
-
84868582029
-
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient
-
Paulsen, B., da, S., Maciel, R., de, M., Galina, A., da Silveira, M.S., Souza, C., dos, S., Drummond, H., Pozzatto, E.N., Junior, H.S., Chicaybam, L., Massuda, R., Setti-Perdigão, P., Bonamino, M., Belmonte-de-Abreu, P.S., Castro, N.G., Brentani, H., Rehen, S.K., Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient. Cell Transplant. 21 (2012), 1547–1559, 10.3727/096368911X600957.
-
(2012)
Cell Transplant.
, vol.21
, pp. 1547-1559
-
-
Paulsen, B.1
da, S.2
Maciel, R.3
de, M.4
Galina, A.5
da Silveira, M.S.6
Souza, C.7
dos, S.8
Drummond, H.9
Pozzatto, E.N.10
Junior, H.S.11
Chicaybam, L.12
Massuda, R.13
Setti-Perdigão, P.14
Bonamino, M.15
Belmonte-de-Abreu, P.S.16
Castro, N.G.17
Brentani, H.18
Rehen, S.K.19
-
76
-
-
0035510566
-
Mice deleted for the DiGeorge/velocardiofacial syndrome region show abnormal sensorimotor gating and learning and memory impairments
-
Paylor, R., Mice deleted for the DiGeorge/velocardiofacial syndrome region show abnormal sensorimotor gating and learning and memory impairments. Hum. Mol. Genet. 10 (2001), 2645–2650, 10.1093/hmg/10.23.2645.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 2645-2650
-
-
Paylor, R.1
-
77
-
-
33745196411
-
Mouse models of 22q11 deletion syndrome
-
Paylor, R., Lindsay, E., Mouse models of 22q11 deletion syndrome. Biol. Psychiatry 59 (2006), 1172–1179, 10.1016/j.biopsych.2006.01.018.
-
(2006)
Biol. Psychiatry
, vol.59
, pp. 1172-1179
-
-
Paylor, R.1
Lindsay, E.2
-
78
-
-
84930520305
-
Novel findings from CNVs implicate inhibitory and excitatory signaling complexes in schizophrenia
-
Pocklington, A.J., Rees, E., Walters, J.T.R., Han, J., Kavanagh, D.H., Chambert, K.D., Holmans, P., Moran, J.L., McCarroll, S.A., Kirov, G., O'Donovan, M.C., Owen, M.J., Novel findings from CNVs implicate inhibitory and excitatory signaling complexes in schizophrenia. Neuron 86 (2015), 1203–1214, 10.1016/j.neuron.2015.04.022.
-
(2015)
Neuron
, vol.86
, pp. 1203-1214
-
-
Pocklington, A.J.1
Rees, E.2
Walters, J.T.R.3
Han, J.4
Kavanagh, D.H.5
Chambert, K.D.6
Holmans, P.7
Moran, J.L.8
McCarroll, S.A.9
Kirov, G.10
O'Donovan, M.C.11
Owen, M.J.12
-
79
-
-
84893904007
-
A polygenic burden of rare disruptive mutations in schizophrenia
-
Purcell, S.M., Moran, J.L., Fromer, M., Ruderfer, D., Solovieff, N., Roussos, P., O'Dushlaine, C., Chambert, K., Bergen, S.E., Kähler, A., Duncan, L., Stahl, E., Genovese, G., Fernández, E., Collins, M.O., Komiyama, N.H., Choudhary, J.S., Magnusson, P.K.E., Banks, E., Shakir, K., Garimella, K., Fennell, T., DePristo, M., Grant, S.G.N., Haggarty, S.J., Gabriel, S., Scolnick, E.M., Lander, E.S., Hultman, C.M., Sullivan, P.F., McCarroll, S. a, Sklar, P., A polygenic burden of rare disruptive mutations in schizophrenia. Nature 506 (2014), 185–190, 10.1038/nature12975.
-
(2014)
Nature
, vol.506
, pp. 185-190
-
-
Purcell, S.M.1
Moran, J.L.2
Fromer, M.3
Ruderfer, D.4
Solovieff, N.5
Roussos, P.6
O'Dushlaine, C.7
Chambert, K.8
Bergen, S.E.9
Kähler, A.10
Duncan, L.11
Stahl, E.12
Genovese, G.13
Fernández, E.14
Collins, M.O.15
Komiyama, N.H.16
Choudhary, J.S.17
Magnusson, P.K.E.18
Banks, E.19
Shakir, K.20
Garimella, K.21
Fennell, T.22
DePristo, M.23
Grant, S.G.N.24
Haggarty, S.J.25
Gabriel, S.26
Scolnick, E.M.27
Lander, E.S.28
Hultman, C.M.29
Sullivan, P.F.30
McCarroll, S.A.31
Sklar, P.32
more..
-
80
-
-
84904731433
-
Neurexin dysfunction in adult neurons results in autistic-like behavior in mice
-
Rabaneda, L.G., Robles-Lanuza, E., Nieto-González, J., Scholl, F.G., Neurexin dysfunction in adult neurons results in autistic-like behavior in mice. Cell Rep 8 (2014), 338–346, 10.1016/j.celrep.2014.06.022.
-
(2014)
Cell Rep
, vol.8
, pp. 338-346
-
-
Rabaneda, L.G.1
Robles-Lanuza, E.2
Nieto-González, J.3
Scholl, F.G.4
-
81
-
-
84887010498
-
Genome engineering using the CRISPR-Cas9 system
-
Ran, F.A., Hsu, P.P.D., Wright, J., Agarwala, V., Scott, D. a, Zhang, F., Genome engineering using the CRISPR-Cas9 system. Nat. Protoc. 8 (2013), 2281–2308, 10.1038/nprot.2013.143.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 2281-2308
-
-
Ran, F.A.1
Hsu, P.P.D.2
Wright, J.3
Agarwala, V.4
Scott, D.A.5
Zhang, F.6
-
82
-
-
84891142540
-
Evidence that duplications of 22q11.2 protect against schizophrenia
-
Rees, E., Kirov, G., Sanders, a, Walters, J.T.R., Chambert, K.D., Shi, J., Szatkiewicz, J., O'Dushlaine, C., Richards, a L., Green, E.K., Jones, I., Davies, G., Legge, S.E., Moran, J.L., Pato, C., Pato, M., Genovese, G., Levinson, D., Duan, J., Moy, W., Göring, H.H.H., Morris, D., Cormican, P., Kendler, K.S., O'Neill, F. a, Riley, B., Gill, M., Corvin, a, Craddock, N., Sklar, P., Hultman, C., Sullivan, P.F., Gejman, P.V., McCarroll, S. a, O'Donovan, M.C., Owen, M.J., Evidence that duplications of 22q11.2 protect against schizophrenia. Mol. Psychiatry 19 (2014), 37–40, 10.1038/mp.2013.156.
-
(2014)
Mol. Psychiatry
, vol.19
, pp. 37-40
-
-
Rees, E.1
Kirov, G.2
Sanders, A.3
Walters, J.T.R.4
Chambert, K.D.5
Shi, J.6
Szatkiewicz, J.7
O'Dushlaine, C.8
Richards, A.L.9
Green, E.K.10
Jones, I.11
Davies, G.12
Legge, S.E.13
Moran, J.L.14
Pato, C.15
Pato, M.16
Genovese, G.17
Levinson, D.18
Duan, J.19
Moy, W.20
Göring, H.H.H.21
Morris, D.22
Cormican, P.23
Kendler, K.S.24
O'Neill, F.A.25
Riley, B.26
Gill, M.27
Corvin, A.28
Craddock, N.29
Sklar, P.30
Hultman, C.31
Sullivan, P.F.32
Gejman, P.V.33
McCarroll, S.A.34
O'Donovan, M.C.35
Owen, M.J.36
more..
-
83
-
-
84893611579
-
Analysis of copy number variations at 15 schizophrenia-associated loci
-
Rees, E., Walters, J.T.R., Georgieva, L., Isles, A.R., Chambert, K.D., Richards, A.L., Mahoney-Davies, G., Legge, S.E., Moran, J.L., McCarroll, S. a, O'Donovan, M.C., Owen, M.J., Kirov, G., Analysis of copy number variations at 15 schizophrenia-associated loci. Br. J. Psychiatry 204 (2014), 108–114, 10.1192/bjp.bp.113.131052.
-
(2014)
Br. J. Psychiatry
, vol.204
, pp. 108-114
-
-
Rees, E.1
Walters, J.T.R.2
Georgieva, L.3
Isles, A.R.4
Chambert, K.D.5
Richards, A.L.6
Mahoney-Davies, G.7
Legge, S.E.8
Moran, J.L.9
McCarroll, S.A.10
O'Donovan, M.C.11
Owen, M.J.12
Kirov, G.13
-
84
-
-
84904804929
-
Biological insights from 108 schizophrenia-associated genetic loci
-
Ripke, S., Neale, B.M., Corvin, A., Walters, J.T.R., Farh, K.-H., Holmans, P. a, Lee, P., Bulik-Sullivan, B., Collier, D. a, Huang, H., Pers, T.H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. a, Begemann, M., Belliveau Jr, R. a, Bene, J., Bergen, S.E., Bevilacqua, E., Bigdeli, T.B., Black, D.W., Bruggeman, R., Buccola, N.G., Buckner, R.L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R.M., Carr, V.J., Carrera, N., Catts, S.V., Chambert, K.D., Chan, R.C.K., Chen, R.Y.L., Chen, E.Y.H., Cheng, W., Cheung, E.F.C., Ann Chong, S., Robert Cloninger, C., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J.J., Curtis, D., Davidson, M., Davis, K.L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A.H., Farrell, M.S., Frank, J., Franke, L., Freedman, R., Freimer, N.B., Friedl, M., Friedman, J.I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J.I., Golimbet, V., Gopal, S., Gratten, J., de Haan, L., Hammer, C., Hamshere, M.L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A.M., Henskens, F. a, Herms, S., Hirschhorn, J.N., Hoffmann, P., Hofman, A., Hollegaard, M.V., Hougaard, D.M., Ikeda, M., Joa, I., Julià, A., Kahn, R.S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M.C., Kennedy, J.L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. a, Konte, B., Kucinskas, V., Ausrele Kucinskiene, Z., Kuzelova-Ptackova, H., Kähler, A.K., Laurent, C., Keong, Lee Chee, Hong Lee, J., Legge, S., Lerer, S.E., Li, B., Li, M., Liang, T., Lieberman, K.-Y., Limborska, J., Loughland, S., Lubinski, C.M., Lönnqvist, J., Macek Jr, J., Magnusson, M., Maher, P.K.E., Maier, B.S., Mallet, W., Marsal, J., Mattheisen, S., Mattingsdal, M., McCarley, M., McDonald, R.W., McIntosh, C., Meier, A.M., Meijer, S., Melegh, C.J., Melle, B., Mesholam-Gately, I., Metspalu, R.I., Michie, A., Milani, P.T., Milanova, L., Mokrab, V., Morris, Y., Mors, D.W., Murphy, O., Murray, K.C., Myin-Germeys, R.M., Müller-Myhsok, I., Nelis, B., Nenadic, M., Nertney, I., Nestadt, D. a, Nicodemus, G., Nikitina-Zake, K.K., Nisenbaum, L., Nordin, L., O'Callaghan, A., O'Dushlaine, C., E., O'Neill, F.A., Oh, S.-Y., Olincy, A., Olsen, L., Van Os, J., Endophenotypes International Consortium, P., Pantelis, C., Papadimitriou, G.N., Papiol, S., Parkhomenko, E., Pato, M.T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D.O., Pietiläinen, O., Pimm, J., Pocklington, A.J., Powell, J., Price, A., Pulver, A.E., Purcell, S.M., Quested, D., Rasmussen, H.B., Reichenberg, A., Reimers, M. a, Richards, A.L., Roffman, J.L., Roussos, P., Ruderfer, D.M., Salomaa, V., Sanders, A.R., Schall, U., Schubert, C.R., Schulze, T.G., Schwab, S.G., Scolnick, E.M., Scott, R.J., Seidman, L.J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J.M., Sim, K., Slominsky, P., Smoller, J.W., So, H.-C., Spencer, C. a, Stahl, E. a, Stefansson, H., Steinberg, S., Stogmann, E., Straub, R.E., Strengman, E., Strohmaier, J., Scott Stroup, T., Subramaniam, M., Suvisaari, J., Svrakic, D.M., Szatkiewicz, J.P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B.T., Weiser, M., Wildenauer, D.B., Williams, N.M., Williams, S., Witt, S.H., Wolen, A.R., Wong, E.H.M., Wormley, B.K., Simon Xi, H., Zai, C.C., Zheng, X., Zimprich, F., Wray, N.R., Stefansson, K., Visscher, P.M., Trust Case-Control Consortium, W., Adolfsson, R., Andreassen, O. a, Blackwood, D.H.R., Bramon, E., Buxbaum, J.D., Børglum, A.D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P.V., Gill, M., Gurling, H., Hultman, C.M., Iwata, N., Jablensky, A.V., Jönsson, E.G., Kendler, K.S., Kirov, G., Knight, J., Lencz, T., Levinson, D.F., Li, Q.S., Liu, J., Malhotra, A.K., McCarroll, S. a, McQuillin, A., Moran, J.L., Mortensen, P.B., Mowry, B.J., Nöthen, M.M., Ophoff, R. a, Owen, M.J., Palotie, A., Pato, C.N., Petryshen, T.L., Posthuma, D., Rietschel, M., Riley, B.P., Rujescu, D., Sham, P.C., Sklar, P., St Clair, D., Weinberger, D.R., Wendland, J.R., Werge, T., Daly, M.J., Sullivan, P.F., O'Donovan, M.C., Biological insights from 108 schizophrenia-associated genetic loci. Nature 511 (2014), 421–427, 10.1038/nature13595.
-
(2014)
Nature
, vol.511
, pp. 421-427
-
-
Ripke, S.1
Neale, B.M.2
Corvin, A.3
Walters, J.T.R.4
Farh, K.-H.5
Holmans, P.A.6
Lee, P.7
Bulik-Sullivan, B.8
Collier, D.A.9
Huang, H.10
Pers, T.H.11
Agartz, I.12
Agerbo, E.13
Albus, M.14
Alexander, M.15
Amin, F.16
Bacanu, S.A.17
Begemann, M.18
Belliveau Jr, R.A.19
Bene, J.20
Bergen, S.E.21
Bevilacqua, E.22
Bigdeli, T.B.23
Black, D.W.24
Bruggeman, R.25
Buccola, N.G.26
Buckner, R.L.27
Byerley, W.28
Cahn, W.29
Cai, G.30
Campion, D.31
Cantor, R.M.32
Carr, V.J.33
Carrera, N.34
Catts, S.V.35
Chambert, K.D.36
Chan, R.C.K.37
Chen, R.Y.L.38
Chen, E.Y.H.39
Cheng, W.40
Cheung, E.F.C.41
Ann Chong, S.42
Robert Cloninger, C.43
Cohen, D.44
Cohen, N.45
Cormican, P.46
Craddock, N.47
Crowley, J.J.48
Curtis, D.49
Davidson, M.50
Davis, K.L.51
Degenhardt, F.52
Del Favero, J.53
Demontis, D.54
Dikeos, D.55
Dinan, T.56
Djurovic, S.57
Donohoe, G.58
Drapeau, E.59
Duan, J.60
Dudbridge, F.61
Durmishi, N.62
Eichhammer, P.63
Eriksson, J.64
Escott-Price, V.65
Essioux, L.66
Fanous, A.H.67
Farrell, M.S.68
Frank, J.69
Franke, L.70
Freedman, R.71
Freimer, N.B.72
Friedl, M.73
Friedman, J.I.74
Fromer, M.75
Genovese, G.76
Georgieva, L.77
Giegling, I.78
Giusti-Rodríguez, P.79
Godard, S.80
Goldstein, J.I.81
Golimbet, V.82
Gopal, S.83
Gratten, J.84
de Haan, L.85
Hammer, C.86
Hamshere, M.L.87
Hansen, M.88
Hansen, T.89
Haroutunian, V.90
Hartmann, A.M.91
Henskens, F.A.92
Herms, S.93
Hirschhorn, J.N.94
Hoffmann, P.95
Hofman, A.96
Hollegaard, M.V.97
Hougaard, D.M.98
Ikeda, M.99
Joa, I.100
Julià, A.101
Kahn, R.S.102
Kalaydjieva, L.103
Karachanak-Yankova, S.104
Karjalainen, J.105
Kavanagh, D.106
Keller, M.C.107
Kennedy, J.L.108
Khrunin, A.109
Kim, Y.110
Klovins, J.111
Knowles, J.A.112
Konte, B.113
Kucinskas, V.114
Ausrele Kucinskiene, Z.115
Kuzelova-Ptackova, H.116
Kähler, A.K.117
Laurent, C.118
Keong, L.C.119
Hong Lee, J.120
Legge, S.121
Lerer, S.E.122
Li, B.123
Li, M.124
Liang, T.125
Lieberman, K.-Y.126
Limborska, J.127
Loughland, S.128
Lubinski, C.M.129
Lönnqvist, J.130
Macek Jr, J.131
Magnusson, M.132
Maher, P.K.E.133
Maier, B.S.134
Mallet, W.135
Marsal, J.136
Mattheisen, S.137
Mattingsdal, M.138
McCarley, M.139
McDonald, R.W.140
McIntosh, C.141
Meier, A.M.142
Meijer, S.143
Melegh, C.J.144
Melle, B.145
Mesholam-Gately, I.146
Metspalu, R.I.147
Michie, A.148
Milani, P.T.149
Milanova, L.150
Mokrab, V.151
Morris, Y.152
Mors, D.W.153
Murphy, O.154
Murray, K.C.155
Myin-Germeys, R.M.156
Müller-Myhsok, I.157
Nelis, B.158
Nenadic, M.159
Nertney, I.160
Nestadt, D.A.161
Nicodemus, G.162
Nikitina-Zake, K.K.163
Nisenbaum, L.164
Nordin, L.165
O'Callaghan, A.166
O'Dushlaine, C.E.167
O'Neill, F.A.168
Oh, S.-Y.169
Olincy, A.170
Olsen, L.171
Van Os, J.172
Endophenotypes International Consortium, P.173
Pantelis, C.174
Papadimitriou, G.N.175
Papiol, S.176
Parkhomenko, E.177
Pato, M.T.178
Paunio, T.179
Pejovic-Milovancevic, M.180
Perkins, D.O.181
Pietiläinen, O.182
Pimm, J.183
Pocklington, A.J.184
Powell, J.185
Price, A.186
Pulver, A.E.187
Purcell, S.M.188
Quested, D.189
Rasmussen, H.B.190
Reichenberg, A.191
Reimers, M.A.192
Richards, A.L.193
Roffman, J.L.194
Roussos, P.195
Ruderfer, D.M.196
Salomaa, V.197
Sanders, A.R.198
Schall, U.199
Schubert, C.R.200
Schulze, T.G.201
Schwab, S.G.202
Scolnick, E.M.203
Scott, R.J.204
Seidman, L.J.205
Shi, J.206
Sigurdsson, E.207
Silagadze, T.208
Silverman, J.M.209
Sim, K.210
Slominsky, P.211
Smoller, J.W.212
So, H.-C.213
Spencer, C.A.214
Stahl, E.A.215
Stefansson, H.216
Steinberg, S.217
Stogmann, E.218
Straub, R.E.219
Strengman, E.220
Strohmaier, J.221
Scott Stroup, T.222
Subramaniam, M.223
Suvisaari, J.224
Svrakic, D.M.225
Szatkiewicz, J.P.226
Söderman, E.227
Thirumalai, S.228
Toncheva, D.229
Tosato, S.230
Veijola, J.231
Waddington, J.232
Walsh, D.233
Wang, D.234
Wang, Q.235
Webb, B.T.236
Weiser, M.237
Wildenauer, D.B.238
Williams, N.M.239
Williams, S.240
Witt, S.H.241
Wolen, A.R.242
Wong, E.H.M.243
Wormley, B.K.244
Simon Xi, H.245
Zai, C.C.246
Zheng, X.247
Zimprich, F.248
Wray, N.R.249
Stefansson, K.250
Visscher, P.M.251
Trust Case-Control Consortium, W.252
Adolfsson, R.253
Andreassen, O.A.254
Blackwood, D.H.R.255
Bramon, E.256
Buxbaum, J.D.257
Børglum, A.D.258
Cichon, S.259
Darvasi, A.260
Domenici, E.261
Ehrenreich, H.262
Esko, T.263
Gejman, P.V.264
Gill, M.265
Gurling, H.266
Hultman, C.M.267
Iwata, N.268
Jablensky, A.V.269
Jönsson, E.G.270
Kendler, K.S.271
Kirov, G.272
Knight, J.273
Lencz, T.274
Levinson, D.F.275
Li, Q.S.276
Liu, J.277
Malhotra, A.K.278
McCarroll, S.A.279
McQuillin, A.280
Moran, J.L.281
Mortensen, P.B.282
Mowry, B.J.283
Nöthen, M.M.284
Ophoff, R.A.285
Owen, M.J.286
Palotie, A.287
Pato, C.N.288
Petryshen, T.L.289
Posthuma, D.290
Rietschel, M.291
Riley, B.P.292
Rujescu, D.293
Sham, P.C.294
Sklar, P.295
St Clair, D.296
Weinberger, D.R.297
Wendland, J.R.298
Werge, T.299
Daly, M.J.300
Sullivan, P.F.301
O'Donovan, M.C.302
more..
-
85
-
-
84884669370
-
Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients
-
Robicsek, O., Karry, R., Petit, I., Salman-Kesner, N., Müller, F.-J., Klein, E., Aberdam, D., Ben-Shachar, D., Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients. Mol. Psychiatry 18 (2013), 1067–1076, 10.1038/mp.2013.67.
-
(2013)
Mol. Psychiatry
, vol.18
, pp. 1067-1076
-
-
Robicsek, O.1
Karry, R.2
Petit, I.3
Salman-Kesner, N.4
Müller, F.-J.5
Klein, E.6
Aberdam, D.7
Ben-Shachar, D.8
-
86
-
-
1542313966
-
Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder
-
Robinson, D.G., Woerner, M.G., McMeniman, M., Mendelowitz, A., Bilder, R.M., Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder. Am. J. Psychiatry 161 (2004), 473–479, 10.1176/appi.ajp.161.3.473.
-
(2004)
Am. J. Psychiatry
, vol.161
, pp. 473-479
-
-
Robinson, D.G.1
Woerner, M.G.2
McMeniman, M.3
Mendelowitz, A.4
Bilder, R.M.5
-
87
-
-
34548668183
-
Structural variation in the human genome: the impact of copy number variants on clinical diagnosis
-
Rodriguez-Revenga, L., Mila, M., Rosenberg, C., Lamb, A., Lee, C., Structural variation in the human genome: the impact of copy number variants on clinical diagnosis. Genet. Med. 9 (2007), 600–606, 10.1097/GIM.0b013e318149e1e3.
-
(2007)
Genet. Med.
, vol.9
, pp. 600-606
-
-
Rodriguez-Revenga, L.1
Mila, M.2
Rosenberg, C.3
Lamb, A.4
Lee, C.5
-
88
-
-
84868203369
-
Genomic stability in reprogramming
-
Ronen, D., Benvenisty, N., Genomic stability in reprogramming. Curr. Opin. Genet. Dev. 22 (2012), 444–449, 10.1016/j.gde.2012.09.003.
-
(2012)
Curr. Opin. Genet. Dev.
, vol.22
, pp. 444-449
-
-
Ronen, D.1
Benvenisty, N.2
-
89
-
-
84921718446
-
Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders
-
Schadt, E.E., Buchanan, S., Brennand, K.J., Merchant, K.M., Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders. Front. Pharmacol. 5 (2014), 1–15, 10.3389/fphar.2014.00252.
-
(2014)
Front. Pharmacol.
, vol.5
, pp. 1-15
-
-
Schadt, E.E.1
Buchanan, S.2
Brennand, K.J.3
Merchant, K.M.4
-
90
-
-
84925341709
-
A comparison of non-integrating reprogramming methods
-
Schlaeger, T.M., Daheron, L., Brickler, T.R., Entwisle, S., Chan, K., Cianci, A., DeVine, A., Ettenger, A., Fitzgerald, K., Godfrey, M., Gupta, D., McPherson, J., Malwadkar, P., Gupta, M., Bell, B., Doi, A., Jung, N., Li, X., Lynes, M.S., Brookes, E., Cherry, A.B.C., Demirbas, D., Tsankov, A.M., Zon, L.I., Rubin, L.L., Feinberg, A.P., Meissner, A., Cowan, C. a, Daley, G.Q., A comparison of non-integrating reprogramming methods. Nat. Biotechnol. 33 (2014), 55–60, 10.1038/nbt.3070.
-
(2014)
Nat. Biotechnol.
, vol.33
, pp. 55-60
-
-
Schlaeger, T.M.1
Daheron, L.2
Brickler, T.R.3
Entwisle, S.4
Chan, K.5
Cianci, A.6
DeVine, A.7
Ettenger, A.8
Fitzgerald, K.9
Godfrey, M.10
Gupta, D.11
McPherson, J.12
Malwadkar, P.13
Gupta, M.14
Bell, B.15
Doi, A.16
Jung, N.17
Li, X.18
Lynes, M.S.19
Brookes, E.20
Cherry, A.B.C.21
Demirbas, D.22
Tsankov, A.M.23
Zon, L.I.24
Rubin, L.L.25
Feinberg, A.P.26
Meissner, A.27
Cowan, C.A.28
Daley, G.Q.29
more..
-
91
-
-
84901937317
-
Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the international consortium on brain and behavior in 22q11.2 deletion syndrome
-
Schneider, M., Debbané, M., Bassett, A.S., Chow, E.W.C., Fung, W.L.A., van den Bree, M.B.M., Owen, M., Murphy, K.C., Niarchou, M., Kates, W.R., Antshel, K.M., Fremont, W., McDonald-McGinn, D.M., Gur, R.E., Zackai, E.H., Vorstman, J., Duijff, S.N., Klaassen, P.W.J., Swillen, A., Gothelf, D., Green, T., Weizman, A., Van Amelsvoort, T., Evers, L., Boot, E., Shashi, V., Hooper, S.R., Bearden, C.E., Jalbrzikowski, M., Armando, M., Vicari, S., Murphy, D.G., Ousley, O., Campbell, L.E., Simon, T.J., Eliez, S., Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the international consortium on brain and behavior in 22q11.2 deletion syndrome. Am. J. Psychiatry 171 (2014), 627–639, 10.1176/appi.ajp.2013.13070864.
-
(2014)
Am. J. Psychiatry
, vol.171
, pp. 627-639
-
-
Schneider, M.1
Debbané, M.2
Bassett, A.S.3
Chow, E.W.C.4
Fung, W.L.A.5
van den Bree, M.B.M.6
Owen, M.7
Murphy, K.C.8
Niarchou, M.9
Kates, W.R.10
Antshel, K.M.11
Fremont, W.12
McDonald-McGinn, D.M.13
Gur, R.E.14
Zackai, E.H.15
Vorstman, J.16
Duijff, S.N.17
Klaassen, P.W.J.18
Swillen, A.19
Gothelf, D.20
Green, T.21
Weizman, A.22
Van Amelsvoort, T.23
Evers, L.24
Boot, E.25
Shashi, V.26
Hooper, S.R.27
Bearden, C.E.28
Jalbrzikowski, M.29
Armando, M.30
Vicari, S.31
Murphy, D.G.32
Ousley, O.33
Campbell, L.E.34
Simon, T.J.35
Eliez, S.36
more..
-
92
-
-
84887627330
-
SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
-
Shcheglovitov, A., Shcheglovitova, O., Yazawa, M., Portmann, T., Shu, R., Sebastiano, V., Krawisz, A., Froehlich, W., Bernstein, J.a., Hallmayer, J.F., Dolmetsch, R.E., SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature 503 (2013), 267–271, 10.1038/nature12618.
-
(2013)
Nature
, vol.503
, pp. 267-271
-
-
Shcheglovitov, A.1
Shcheglovitova, O.2
Yazawa, M.3
Portmann, T.4
Shu, R.5
Sebastiano, V.6
Krawisz, A.7
Froehlich, W.8
Bernstein, J.A.9
Hallmayer, J.F.10
Dolmetsch, R.E.11
-
93
-
-
84862778046
-
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
-
Shi, Y., Kirwan, P., Smith, J., Robinson, H.P.C., Livesey, F.J., Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat. Neurosci. 15 (2012), 477–486, 10.1038/nn.3041.
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 477-486
-
-
Shi, Y.1
Kirwan, P.2
Smith, J.3
Robinson, H.P.C.4
Livesey, F.J.5
-
94
-
-
77950431449
-
Impaired hippocampal–prefrontal synchrony in a genetic mouse model of schizophrenia
-
Sigurdsson, T., Stark, K.L., Karayiorgou, M., Gogos, J. a, Gordon, J. a, Impaired hippocampal–prefrontal synchrony in a genetic mouse model of schizophrenia. Nature 464 (2010), 763–767, 10.1038/nature08855.
-
(2010)
Nature
, vol.464
, pp. 763-767
-
-
Sigurdsson, T.1
Stark, K.L.2
Karayiorgou, M.3
Gogos, J.A.4
Gordon, J.A.5
-
95
-
-
84891711854
-
Efficacy of antipsychotic drugs for schizophrenia
-
Siu, C.O., Agid, O., Remington, G., Efficacy of antipsychotic drugs for schizophrenia. Lancet, 382, 2013, 1874, 10.1016/S0140-6736(13)62616-1.
-
(2013)
Lancet
, vol.382
, pp. 1874
-
-
Siu, C.O.1
Agid, O.2
Remington, G.3
-
96
-
-
43949124669
-
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
-
Stark, K.L., Xu, B., Bagchi, A., Lai, W.-S., Liu, H., Hsu, R., Wan, X., Pavlidis, P., Mills, A. a, Karayiorgou, M., Gogos, J. a, Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat. Genet. 40 (2008), 751–760, 10.1038/ng.138.
-
(2008)
Nat. Genet.
, vol.40
, pp. 751-760
-
-
Stark, K.L.1
Xu, B.2
Bagchi, A.3
Lai, W.-S.4
Liu, H.5
Hsu, R.6
Wan, X.7
Pavlidis, P.8
Mills, A.A.9
Karayiorgou, M.10
Gogos, J.A.11
-
97
-
-
84892620880
-
CNVs conferring risk of autism or schizophrenia affect cognition in controls
-
Stefansson, H., Meyer-Lindenberg, A., Steinberg, S., Magnusdottir, B., Morgen, K., Arnarsdottir, S., Bjornsdottir, G., Walters, G.B., Jonsdottir, G. a, Doyle, O.M., Tost, H., Grimm, O., Kristjansdottir, S., Snorrason, H., Davidsdottir, S.R., Gudmundsson, L.J., Jonsson, G.F., Stefansdottir, B., Helgadottir, I., Haraldsson, M., Jonsdottir, B., Thygesen, J.H., Schwarz, A.J., Didriksen, M., Stensbøl, T.B., Brammer, M., Kapur, S., Halldorsson, J.G., Hreidarsson, S., Saemundsen, E., Sigurdsson, E., Stefansson, K., CNVs conferring risk of autism or schizophrenia affect cognition in controls. Nature 505 (2014), 361–366, 10.1038/nature12818.
-
(2014)
Nature
, vol.505
, pp. 361-366
-
-
Stefansson, H.1
Meyer-Lindenberg, A.2
Steinberg, S.3
Magnusdottir, B.4
Morgen, K.5
Arnarsdottir, S.6
Bjornsdottir, G.7
Walters, G.B.8
Jonsdottir, G.A.9
Doyle, O.M.10
Tost, H.11
Grimm, O.12
Kristjansdottir, S.13
Snorrason, H.14
Davidsdottir, S.R.15
Gudmundsson, L.J.16
Jonsson, G.F.17
Stefansdottir, B.18
Helgadottir, I.19
Haraldsson, M.20
Jonsdottir, B.21
Thygesen, J.H.22
Schwarz, A.J.23
Didriksen, M.24
Stensbøl, T.B.25
Brammer, M.26
Kapur, S.27
Halldorsson, J.G.28
Hreidarsson, S.29
Saemundsen, E.30
Sigurdsson, E.31
Stefansson, K.32
more..
-
98
-
-
49949085933
-
Large recurrent microdeletions associated with schizophrenia
-
Stefansson, H., Rujescu, D., Cichon, S., Pietiläinen, O.P.H., Ingason, A., Steinberg, S., Fossdal, R., Sigurdsson, E., Sigmundsson, T., Buizer-Voskamp, J.E., Hansen, T., Jakobsen, K.D., Muglia, P., Francks, C., Matthews, P.M., Gylfason, A., Halldorsson, B.V., Gudbjartsson, D., Thorgeirsson, T.E., Sigurdsson, A., Jonasdottir, A., Jonasdottir, A., Bjornsson, A., Mattiasdottir, S., Blondal, T., Haraldsson, M., Magnusdottir, B.B., Giegling, I., Möller, H.-J., Hartmann, A., Shianna, K.V., Ge, D., Need, A.C., Crombie, C., Fraser, G., Walker, N., Lonnqvist, J., Suvisaari, J., Tuulio-Henriksson, A., Paunio, T., Toulopoulou, T., Bramon, E., Di Forti, M., Murray, R., Ruggeri, M., Vassos, E., Tosato, S., Walshe, M., Li, T., Vasilescu, C., Mühleisen, T.W., Wang, A.G., Ullum, H., Djurovic, S., Melle, I., Olesen, J., Kiemeney, L.A., Franke, B., Sabatti, C., Freimer, N.B., Gulcher, J.R., Thorsteinsdottir, U., Kong, A., Andreassen, O.A., Ophoff, R.A., Georgi, A., Rietschel, M., Werge, T., Petursson, H., Goldstein, D.B., Nöthen, M.M., Peltonen, L., Collier, D.A., St, Clair, D., Stefansson, K., Kahn, R.S., Linszen, D.H., van Os, J., Wiersma, D., Bruggeman, R., Cahn, W., de Haan, L., Krabbendam, L., Myin-Germeys, I., Large recurrent microdeletions associated with schizophrenia. Nature 455 (2008), 232–236, 10.1038/nature07229.
-
(2008)
Nature
, vol.455
, pp. 232-236
-
-
Stefansson, H.1
Rujescu, D.2
Cichon, S.3
Pietiläinen, O.P.H.4
Ingason, A.5
Steinberg, S.6
Fossdal, R.7
Sigurdsson, E.8
Sigmundsson, T.9
Buizer-Voskamp, J.E.10
Hansen, T.11
Jakobsen, K.D.12
Muglia, P.13
Francks, C.14
Matthews, P.M.15
Gylfason, A.16
Halldorsson, B.V.17
Gudbjartsson, D.18
Thorgeirsson, T.E.19
Sigurdsson, A.20
Jonasdottir, A.21
Jonasdottir, A.22
Bjornsson, A.23
Mattiasdottir, S.24
Blondal, T.25
Haraldsson, M.26
Magnusdottir, B.B.27
Giegling, I.28
Möller, H.-J.29
Hartmann, A.30
Shianna, K.V.31
Ge, D.32
Need, A.C.33
Crombie, C.34
Fraser, G.35
Walker, N.36
Lonnqvist, J.37
Suvisaari, J.38
Tuulio-Henriksson, A.39
Paunio, T.40
Toulopoulou, T.41
Bramon, E.42
Di Forti, M.43
Murray, R.44
Ruggeri, M.45
Vassos, E.46
Tosato, S.47
Walshe, M.48
Li, T.49
Vasilescu, C.50
Mühleisen, T.W.51
Wang, A.G.52
Ullum, H.53
Djurovic, S.54
Melle, I.55
Olesen, J.56
Kiemeney, L.A.57
Franke, B.58
Sabatti, C.59
Freimer, N.B.60
Gulcher, J.R.61
Thorsteinsdottir, U.62
Kong, A.63
Andreassen, O.A.64
Ophoff, R.A.65
Georgi, A.66
Rietschel, M.67
Werge, T.68
Petursson, H.69
Goldstein, D.B.70
Nöthen, M.M.71
Peltonen, L.72
Collier, D.A.S.73
Clair, D.74
Stefansson, K.75
Kahn, R.S.76
Linszen, D.H.77
van Os, J.78
Wiersma, D.79
Bruggeman, R.80
Cahn, W.81
de Haan, L.82
Krabbendam, L.83
Myin-Germeys, I.84
more..
-
99
-
-
0344305525
-
Schizophrenia as a Complex Trait
-
Sullivan, P.F., Kendler, K.S., Neale, M.C., Schizophrenia as a Complex Trait. Arch. Gen. Psychiatry, 60, 2003, 1187, 10.1001/archpsyc.60.12.1187.
-
(2003)
Arch. Gen. Psychiatry
, vol.60
, pp. 1187
-
-
Sullivan, P.F.1
Kendler, K.S.2
Neale, M.C.3
-
100
-
-
84892858363
-
Deficient prepulse inhibition in schizophrenia detected by the multi-site COGS
-
Swerdlow, N.R., Light, G.A., Sprock, J., Calkins, M.E., Green, M.F., Greenwood, T.A., Gur, R.E., Gur, R.C., Lazzeroni, L.C., Nuechterlein, K.H., Radant, A.D., Ray, A., Seidman, L.J., Siever, L.J., Silverman, J.M., Stone, W.S., Sugar, C.A., Tsuang, D.W., Tsuang, M.T., Turetsky, B.I., Braff, D.L., Deficient prepulse inhibition in schizophrenia detected by the multi-site COGS. Schizophr. Res. 152 (2014), 503–512, 10.1016/j.schres.2013.12.004.
-
(2014)
Schizophr. Res.
, vol.152
, pp. 503-512
-
-
Swerdlow, N.R.1
Light, G.A.2
Sprock, J.3
Calkins, M.E.4
Green, M.F.5
Greenwood, T.A.6
Gur, R.E.7
Gur, R.C.8
Lazzeroni, L.C.9
Nuechterlein, K.H.10
Radant, A.D.11
Ray, A.12
Seidman, L.J.13
Siever, L.J.14
Silverman, J.M.15
Stone, W.S.16
Sugar, C.A.17
Tsuang, D.W.18
Tsuang, M.T.19
Turetsky, B.I.20
Braff, D.L.21
more..
-
101
-
-
84903649108
-
Copy number variation in schizophrenia in Sweden
-
Szatkiewicz, J.P., O'Dushlaine, C., Chen, G., Chambert, K., Moran, J.L., Neale, B.M., Fromer, M., Ruderfer, D., Akterin, S., Bergen, S.E., Kähler, a, Magnusson, P.K.E., Kim, Y., Crowley, J.J., Rees, E., Kirov, G., O'Donovan, M.C., Owen, M.J., Walters, J., Scolnick, E., Sklar, P., Purcell, S., Hultman, C.M., McCarroll, S. a, Sullivan, P.F., Copy number variation in schizophrenia in Sweden. Mol. Psychiatry 19 (2014), 762–773, 10.1038/mp.2014.40.
-
(2014)
Mol. Psychiatry
, vol.19
, pp. 762-773
-
-
Szatkiewicz, J.P.1
O'Dushlaine, C.2
Chen, G.3
Chambert, K.4
Moran, J.L.5
Neale, B.M.6
Fromer, M.7
Ruderfer, D.8
Akterin, S.9
Bergen, S.E.10
Kähler, A.11
Magnusson, P.K.E.12
Kim, Y.13
Crowley, J.J.14
Rees, E.15
Kirov, G.16
O'Donovan, M.C.17
Owen, M.J.18
Walters, J.19
Scolnick, E.20
Sklar, P.21
Purcell, S.22
Hultman, C.M.23
McCarroll, S.A.24
Sullivan, P.F.25
more..
-
102
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., Yamanaka, S., Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007), 861–872, 10.1016/j.cell.2007.11.019.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
103
-
-
33846424247
-
The failure of torcetrapib: was it the molecule or the mechanism?
-
Tall, A.R., Yvan-Charvet, L., Wang, N., The failure of torcetrapib: was it the molecule or the mechanism?. Arterioscler. Thromb. Vasc. Biol. 27 (2007), 257–260, 10.1161/01.ATV.0000256728.60226.77.
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 257-260
-
-
Tall, A.R.1
Yvan-Charvet, L.2
Wang, N.3
-
104
-
-
78650730519
-
Decreased exploratory activity in a mouse model of 15q duplication syndrome: implications for disturbance of serotonin signaling
-
Tamada, K., Tomonaga, S., Hatanaka, F., Nakai, N., Takao, K., Miyakawa, T., Nakatani, J., Takumi, T., Decreased exploratory activity in a mouse model of 15q duplication syndrome: implications for disturbance of serotonin signaling. PLoS One, 5, 2010, e15126, 10.1371/journal.pone.0015126.
-
(2010)
PLoS One
, vol.5
, pp. e15126
-
-
Tamada, K.1
Tomonaga, S.2
Hatanaka, F.3
Nakai, N.4
Takao, K.5
Miyakawa, T.6
Nakatani, J.7
Takumi, T.8
-
105
-
-
42349088634
-
Rare Structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
-
(80-.)
-
Walsh, T., McClellan, J.M., McCarthy, S.E., Addington, A.M., Pierce, S.B., Cooper, G.M., Nord, A.S., Kusenda, M., Malhotra, D., Bhandari, A., Stray, S.M., Rippey, C.F., Roccanova, P., Makarov, V., Lakshmi, B., Findling, R.L., Sikich, L., Stromberg, T., Merriman, B., Gogtay, N., Butler, P., Eckstrand, K., Noory, L., Gochman, P., Long, R., Chen, Z., Davis, S., Baker, C., Eichler, E.E., Meltzer, P.S., Nelson, S.F., Singleton, A.B., Lee, M.K., Rapoport, J.L., King, M.-C., Sebat, J., Rare Structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 320 (2008), 539–543, 10.1126/science.1155174 (80-. ).
-
(2008)
Science
, vol.320
, pp. 539-543
-
-
Walsh, T.1
McClellan, J.M.2
McCarthy, S.E.3
Addington, A.M.4
Pierce, S.B.5
Cooper, G.M.6
Nord, A.S.7
Kusenda, M.8
Malhotra, D.9
Bhandari, A.10
Stray, S.M.11
Rippey, C.F.12
Roccanova, P.13
Makarov, V.14
Lakshmi, B.15
Findling, R.L.16
Sikich, L.17
Stromberg, T.18
Merriman, B.19
Gogtay, N.20
Butler, P.21
Eckstrand, K.22
Noory, L.23
Gochman, P.24
Long, R.25
Chen, Z.26
Davis, S.27
Baker, C.28
Eichler, E.E.29
Meltzer, P.S.30
Nelson, S.F.31
Singleton, A.B.32
Lee, M.K.33
Rapoport, J.L.34
King, M.-C.35
Sebat, J.36
more..
-
106
-
-
0037965627
-
Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance
-
Walz, K., Caratini-Rivera, S., Bi, W., Fonseca, P., Mansouri, D.L., Lynch, J., Vogel, H., Noebels, J.L., Bradley, A., Lupski, J.R., Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance. Mol. Cell. Biol. 23 (2003), 3646–3655, 10.1128/MCB.23.10.3646-3655.2003.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3646-3655
-
-
Walz, K.1
Caratini-Rivera, S.2
Bi, W.3
Fonseca, P.4
Mansouri, D.L.5
Lynch, J.6
Vogel, H.7
Noebels, J.L.8
Bradley, A.9
Lupski, J.R.10
-
107
-
-
33847323881
-
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
-
Wang, Y., Medvid, R., Melton, C., Jaenisch, R., Blelloch, R., DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat. Genet. 39 (2007), 380–385, 10.1038/ng1969.
-
(2007)
Nat. Genet.
, vol.39
, pp. 380-385
-
-
Wang, Y.1
Medvid, R.2
Melton, C.3
Jaenisch, R.4
Blelloch, R.5
-
108
-
-
84918558417
-
Copy number variable micrornas in schizophrenia and their neurodevelopmental gene targets
-
Warnica, W., Merico, D., Costain, G., Alfred, S.E., Wei, J., Marshall, C.R., Scherer, S.W., Bassett, A.S., Copy number variable micrornas in schizophrenia and their neurodevelopmental gene targets. Biol. Psychiatry 77 (2014), 158–166, 10.1016/j.biopsych.2014.05.011.
-
(2014)
Biol. Psychiatry
, vol.77
, pp. 158-166
-
-
Warnica, W.1
Merico, D.2
Costain, G.3
Alfred, S.E.4
Wei, J.5
Marshall, C.R.6
Scherer, S.W.7
Bassett, A.S.8
-
109
-
-
0023215296
-
Implications of normal brain development for the pathogenesis of schizophrenia
-
Weinberger, D.R., Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry 44 (1987), 660–669, 10.1001/archpsyc.1988.01800350089019.
-
(1987)
Arch. Gen. Psychiatry
, vol.44
, pp. 660-669
-
-
Weinberger, D.R.1
-
110
-
-
39049163023
-
Association between microdeletion and microduplication at 16p11.2 and autism
-
Weiss, L.A., Shen, Y., Korn, J.M., Arking, D.E., Miller, D.T., Fossdal, R., Saemundsen, E., Stefansson, H., Ferreira, M.A.R., Green, T., Platt, O.S., Ruderfer, D.M., Walsh, C.A., Altshuler, D., Chakravarti, A., Tanzi, R.E., Stefansson, K., Santangelo, S.L., Gusella, J.F., Sklar, P., Wu, B., Daly, M.J., Association between microdeletion and microduplication at 16p11.2 and autism. N. Engl. J. Med. 358 (2008), 667–675, 10.1056/NEJMoa075974.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 667-675
-
-
Weiss, L.A.1
Shen, Y.2
Korn, J.M.3
Arking, D.E.4
Miller, D.T.5
Fossdal, R.6
Saemundsen, E.7
Stefansson, H.8
Ferreira, M.A.R.9
Green, T.10
Platt, O.S.11
Ruderfer, D.M.12
Walsh, C.A.13
Altshuler, D.14
Chakravarti, A.15
Tanzi, R.E.16
Stefansson, K.17
Santangelo, S.L.18
Gusella, J.F.19
Sklar, P.20
Wu, B.21
Daly, M.J.22
more..
-
111
-
-
75749110218
-
Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons
-
Wen, L., Lu, Y.-S., Zhu, X.-H., Li, X.-M., Woo, R.-S., Chen, Y.-J., Yin, D.-M., Lai, C., Terry, A.V., Vazdarjanova, A., Xiong, W.-C., Mei, L., Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 1211–1216, 10.1073/pnas.0910302107.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 1211-1216
-
-
Wen, L.1
Lu, Y.-S.2
Zhu, X.-H.3
Li, X.-M.4
Woo, R.-S.5
Chen, Y.-J.6
Yin, D.-M.7
Lai, C.8
Terry, A.V.9
Vazdarjanova, A.10
Xiong, W.-C.11
Mei, L.12
-
112
-
-
84911360325
-
Synaptic dysregulation in a human iPS cell model of mental disorders
-
Wen, Z., Nguyen, H.N., Guo, Z., Lalli, M. a, Wang, X., Su, Y., Kim, N.-S., Yoon, K.-J., Shin, J., Zhang, C., Makri, G., Nauen, D., Yu, H., Guzman, E., Chiang, C.-H., Yoritomo, N., Kaibuchi, K., Zou, J., Christian, K.M., Cheng, L., Ross, C. a, Margolis, R.L., Chen, G., Kosik, K.S., Song, H., Ming, G., Synaptic dysregulation in a human iPS cell model of mental disorders. Nat. Lett 515 (2014), 1–5, 10.1038/nature13716.
-
(2014)
Nat. Lett
, vol.515
, pp. 1-5
-
-
Wen, Z.1
Nguyen, H.N.2
Guo, Z.3
Lalli, M.A.4
Wang, X.5
Su, Y.6
Kim, N.-S.7
Yoon, K.-J.8
Shin, J.9
Zhang, C.10
Makri, G.11
Nauen, D.12
Yu, H.13
Guzman, E.14
Chiang, C.-H.15
Yoritomo, N.16
Kaibuchi, K.17
Zou, J.18
Christian, K.M.19
Cheng, L.20
Ross, C.A.21
Margolis, R.L.22
Chen, G.23
Kosik, K.S.24
Song, H.25
Ming, G.26
more..
-
113
-
-
84904001347
-
Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity
-
Yoon, K.-J., Nguyen, H.N., Ursini, G., Zhang, F., Kim, N.-S., Wen, Z., Makri, G., Nauen, D., Shin, J.H., Park, Y., Chung, R., Pekle, E., Zhang, C., Towe, M., Hussaini, S.M.Q., Lee, Y., Rujescu, D., St, Clair, D., Kleinman, J.E., Hyde, T.M., Krauss, G., Christian, K.M., Rapoport, J.L., Weinberger, D.R., Song, H., Ming, G., Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity. Cell Stem Cell 15 (2014), 79–91, 10.1016/j.stem.2014.05.003.
-
(2014)
Cell Stem Cell
, vol.15
, pp. 79-91
-
-
Yoon, K.-J.1
Nguyen, H.N.2
Ursini, G.3
Zhang, F.4
Kim, N.-S.5
Wen, Z.6
Makri, G.7
Nauen, D.8
Shin, J.H.9
Park, Y.10
Chung, R.11
Pekle, E.12
Zhang, C.13
Towe, M.14
Hussaini, S.M.Q.15
Lee, Y.16
Rujescu, D.S.17
Clair, D.18
Kleinman, J.E.19
Hyde, T.M.20
Krauss, G.21
Christian, K.M.22
Rapoport, J.L.23
Weinberger, D.R.24
Song, H.25
Ming, G.26
more..
-
114
-
-
84940780822
-
MicroRNA profiling of neurons generated using induced pluripotent stem cells derived from patients with schizophrenia and schizoaffective disorder, and 22q11.2 Del
-
Zhao, D., Lin, M., Chen, J., Pedrosa, E., Hrabovsky, A., Fourcade, H.M., Zheng, D., Lachman, H.M., MicroRNA profiling of neurons generated using induced pluripotent stem cells derived from patients with schizophrenia and schizoaffective disorder, and 22q11.2 Del. PLoS One, 10, 2015, e0132387, 10.1371/journal.pone.0132387.
-
(2015)
PLoS One
, vol.10
, pp. e0132387
-
-
Zhao, D.1
Lin, M.2
Chen, J.3
Pedrosa, E.4
Hrabovsky, A.5
Fourcade, H.M.6
Zheng, D.7
Lachman, H.M.8
|