hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice

Cell Stem Cell

Volumn 15, Issue 5, 2014, Pages 559-573

  Cunningham, Miles ^c   Cho, Jun Hyeong ^d,f   Leung, Amanda ^a,b   Savvidis, George ^a,b   Ahn, Sandra ^a,b   Moon, Minho ^a,b   Lee, Paula K J ^a,b   Han, Jason J ^e   Azimi, Nima ^c   Kim, Kwang Soo ^a,b   Bolshakov, Vadim Y ^d   Chung, Sangmi ^a,b  

^a Department of Psychiatry and Program in Neuroscience

^b HARVARD STEM CELL INSTITUTE   (United States)

^c Department of Psychiatry

^d Department of Psychiatry

^e MCLEAN HOSPITAL   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABNORMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; EMBRYONIC STEM CELL; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GABAERGIC INTERNEURON; GABAERGIC SYSTEM; HIPPOCAMPUS; HUMAN; HUMAN CELL; INTERNEURON; LOCOMOTION; MALE; MAZE TEST; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; OLIGODENDROGLIA; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SEIZURE; STEM CELL TRANSPLANTATION; ANIMAL; ANIMAL BEHAVIOR; CELL MOTION; CYTOLOGY; MEDIAN EMINENCE; NERVE CELL INHIBITION; NONOBESE DIABETIC MOUSE; OPTOGENETICS; PATHOLOGY; PATHOPHYSIOLOGY; SCID MOUSE; SEIZURES; SYNAPTIC POTENTIAL; TRANSPLANTATION; ULTRASTRUCTURE;

MUS;

4 AMINOBUTYRIC ACID RECEPTOR;

ANIMALS; BEHAVIOR, ANIMAL; CELL DIFFERENTIATION; CELL MOVEMENT; FEMALE; GABAERGIC NEURONS; HIPPOCAMPUS; HUMANS; INTERNEURONS; MALE; MEDIAN EMINENCE; MICE, INBRED NOD; MICE, SCID; NEURAL INHIBITION; OPTOGENETICS; PLURIPOTENT STEM CELLS; SEIZURES; STEM CELL TRANSPLANTATION; SYNAPTIC POTENTIALS;

EID: 84922639322     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2014.10.006     Document Type: Article

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