메뉴 건너뛰기




Volumn 86, Issue 5, 2015, Pages 1203-1214

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR;

EID: 84930520305     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2015.04.022     Document Type: Article
Times cited : (153)

References (65)
  • 2
    • 33845794324 scopus 로고    scopus 로고
    • Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks
    • Bartos M., Vida I., Jonas P. Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat. Rev. Neurosci. 2007, 8:45-56.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 45-56
    • Bartos, M.1    Vida, I.2    Jonas, P.3
  • 4
    • 0037096258 scopus 로고    scopus 로고
    • NMDA receptors and L-type voltage-gated calcium channels contribute to long-term potentiation and different components of fear memory formation in the lateral amygdala
    • Bauer E.P., Schafe G.E., LeDoux J.E. NMDA receptors and L-type voltage-gated calcium channels contribute to long-term potentiation and different components of fear memory formation in the lateral amygdala. J. Neurosci. 2002, 22:5239-5249.
    • (2002) J. Neurosci. , vol.22 , pp. 5239-5249
    • Bauer, E.P.1    Schafe, G.E.2    LeDoux, J.E.3
  • 5
    • 84891788593 scopus 로고    scopus 로고
    • The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse
    • Mouse Genome Database Group
    • Blake J.A., Bult C.J., Eppig J.T., Kadin J.A., Richardson J.E. The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse. Nucleic Acids Res. 2014, 42:D810-D817. Mouse Genome Database Group.
    • (2014) Nucleic Acids Res. , vol.42 , pp. D810-D817
    • Blake, J.A.1    Bult, C.J.2    Eppig, J.T.3    Kadin, J.A.4    Richardson, J.E.5
  • 6
    • 3042523540 scopus 로고    scopus 로고
    • Neuronal oscillations in cortical networks
    • Buzsáki G., Draguhn A. Neuronal oscillations in cortical networks. Science 2004, 304:1926-1929.
    • (2004) Science , vol.304 , pp. 1926-1929
    • Buzsáki, G.1    Draguhn, A.2
  • 7
    • 84875842859 scopus 로고    scopus 로고
    • Brain rhythms and neural syntax: implications for efficient coding of cognitive content and neuropsychiatric disease
    • Buzsáki G., Watson B.O. Brain rhythms and neural syntax: implications for efficient coding of cognitive content and neuropsychiatric disease. Dialogues Clin. Neurosci. 2012, 14:345-367.
    • (2012) Dialogues Clin. Neurosci. , vol.14 , pp. 345-367
    • Buzsáki, G.1    Watson, B.O.2
  • 8
    • 84888866315 scopus 로고    scopus 로고
    • Cortical plasticity, excitatory-inhibitory balance, and sensory perception
    • Carcea I., Froemke R.C. Cortical plasticity, excitatory-inhibitory balance, and sensory perception. Prog. Brain Res. 2013, 207:65-90.
    • (2013) Prog. Brain Res. , vol.207 , pp. 65-90
    • Carcea, I.1    Froemke, R.C.2
  • 9
    • 0034060459 scopus 로고    scopus 로고
    • Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics
    • Cardno A.G., Gottesman I.I. Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics. Am. J. Med. Genet. 2000, 97:12-17.
    • (2000) Am. J. Med. Genet. , vol.97 , pp. 12-17
    • Cardno, A.G.1    Gottesman, I.I.2
  • 10
    • 0024247522 scopus 로고
    • The current status of the dopamine hypothesis of schizophrenia
    • Carlsson A. The current status of the dopamine hypothesis of schizophrenia. Neuropsychopharmacology 1988, 1:179-186.
    • (1988) Neuropsychopharmacology , vol.1 , pp. 179-186
    • Carlsson, A.1
  • 13
    • 0032502349 scopus 로고    scopus 로고
    • The disconnection hypothesis
    • Friston K.J. The disconnection hypothesis. Schizophr. Res. 1998, 30:115-125.
    • (1998) Schizophr. Res. , vol.30 , pp. 115-125
    • Friston, K.J.1
  • 14
    • 84901688723 scopus 로고    scopus 로고
    • GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system
    • Fritschy J.M., Panzanelli P. GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system. Eur. J. Neurosci. 2014, 39:1845-1865.
    • (2014) Eur. J. Neurosci. , vol.39 , pp. 1845-1865
    • Fritschy, J.M.1    Panzanelli, P.2
  • 19
    • 38949092526 scopus 로고    scopus 로고
    • Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus?
    • Glykys J., Mann E.O., Mody I. Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus?. J. Neurosci. 2008, 28:1421-1426.
    • (2008) J. Neurosci. , vol.28 , pp. 1421-1426
    • Glykys, J.1    Mann, E.O.2    Mody, I.3
  • 20
    • 84881193129 scopus 로고    scopus 로고
    • Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network
    • Consortium on the Genetics of Schizophrenia (COGS), PAARTNERS Study GroupPAARTNERS Study Group
    • Gulsuner S., Walsh T., Watts A.C., Lee M.K., Thornton A.M., Casadei S., Rippey C., Shahin H., Nimgaonkar V.L., Go R.C., et al. Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell 2013, 154:518-529. Consortium on the Genetics of Schizophrenia (COGS), PAARTNERS Study GroupPAARTNERS Study Group.
    • (2013) Cell , vol.154 , pp. 518-529
    • Gulsuner, S.1    Walsh, T.2    Watts, A.C.3    Lee, M.K.4    Thornton, A.M.5    Casadei, S.6    Rippey, C.7    Shahin, H.8    Nimgaonkar, V.L.9    Go, R.C.10
  • 22
    • 0035077318 scopus 로고    scopus 로고
    • Isolation of 2000-kDa complexes of N-methyl-D-aspartate receptor and postsynaptic density 95 from mouse brain
    • Husi H., Grant S.G. Isolation of 2000-kDa complexes of N-methyl-D-aspartate receptor and postsynaptic density 95 from mouse brain. J. Neurochem. 2001, 77:281-291.
    • (2001) J. Neurochem. , vol.77 , pp. 281-291
    • Husi, H.1    Grant, S.G.2
  • 24
    • 84875119565 scopus 로고    scopus 로고
    • Losing your inhibition: linking cortical GABAergic interneurons to schizophrenia
    • Inan M., Petros T.J., Anderson S.A. Losing your inhibition: linking cortical GABAergic interneurons to schizophrenia. Neurobiol. Dis. 2013, 53:36-48.
    • (2013) Neurobiol. Dis. , vol.53 , pp. 36-48
    • Inan, M.1    Petros, T.J.2    Anderson, S.A.3
  • 25
    • 51649107017 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications increase risk of schizophrenia
    • International Schizophrenia Consortium
    • Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 2008, 455:237-241. International Schizophrenia Consortium.
    • (2008) Nature , vol.455 , pp. 237-241
  • 27
    • 84879096495 scopus 로고    scopus 로고
    • N-methyl-D-aspartic acid receptor activation downregulates expression of δ subunit-containing GABAA receptors in cultured hippocampal neurons
    • Joshi S., Kapur J. N-methyl-D-aspartic acid receptor activation downregulates expression of δ subunit-containing GABAA receptors in cultured hippocampal neurons. Mol. Pharmacol. 2013, 84:1-11.
    • (2013) Mol. Pharmacol. , vol.84 , pp. 1-11
    • Joshi, S.1    Kapur, J.2
  • 28
    • 67749088757 scopus 로고    scopus 로고
    • Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia
    • Kehrer C., Maziashvili N., Dugladze T., Gloveli T. Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia. Front. Mol. Neurosci. 2008, 1:6.
    • (2008) Front. Mol. Neurosci. , vol.1 , pp. 6
    • Kehrer, C.1    Maziashvili, N.2    Dugladze, T.3    Gloveli, T.4
  • 32
    • 25144509345 scopus 로고    scopus 로고
    • Mechanism of action of antipsychotic drugs: from dopamine D(2) receptor antagonism to glutamate NMDA facilitation
    • Laruelle M., Frankle W.G., Narendran R., Kegeles L.S., Abi-Dargham A. Mechanism of action of antipsychotic drugs: from dopamine D(2) receptor antagonism to glutamate NMDA facilitation. Clin. Ther. 2005, 27:S16-S24.
    • (2005) Clin. Ther. , vol.27 , pp. S16-S24
    • Laruelle, M.1    Frankle, W.G.2    Narendran, R.3    Kegeles, L.S.4    Abi-Dargham, A.5
  • 33
    • 79952710338 scopus 로고    scopus 로고
    • Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications
    • Levinson D.F., Duan J., Oh S., Wang K., Sanders A.R., Shi J., Zhang N., Mowry B.J., Olincy A., Amin F., et al. Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. Am. J. Psychiatry 2011, 168:302-316.
    • (2011) Am. J. Psychiatry , vol.168 , pp. 302-316
    • Levinson, D.F.1    Duan, J.2    Oh, S.3    Wang, K.4    Sanders, A.R.5    Shi, J.6    Zhang, N.7    Mowry, B.J.8    Olincy, A.9    Amin, F.10
  • 34
    • 33748474553 scopus 로고    scopus 로고
    • Pathophysiologically based treatment interventions in schizophrenia
    • Lewis D.A., Gonzalez-Burgos G. Pathophysiologically based treatment interventions in schizophrenia. Nat. Med. 2006, 12:1016-1022.
    • (2006) Nat. Med. , vol.12 , pp. 1016-1022
    • Lewis, D.A.1    Gonzalez-Burgos, G.2
  • 35
    • 84855307242 scopus 로고    scopus 로고
    • Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia
    • Lewis D.A., Curley A.A., Glausier J.R., Volk D.W. Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia. Trends Neurosci. 2012, 35:57-67.
    • (2012) Trends Neurosci. , vol.35 , pp. 57-67
    • Lewis, D.A.1    Curley, A.A.2    Glausier, J.R.3    Volk, D.W.4
  • 36
    • 84858434210 scopus 로고    scopus 로고
    • CNVs: harbingers of a rare variant revolution in psychiatric genetics
    • Malhotra D., Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell 2012, 148:1223-1241.
    • (2012) Cell , vol.148 , pp. 1223-1241
    • Malhotra, D.1    Sebat, J.2
  • 38
    • 75549090021 scopus 로고    scopus 로고
    • Control of hippocampal gamma oscillation frequency by tonic inhibition and excitation of interneurons
    • Mann E.O., Mody I. Control of hippocampal gamma oscillation frequency by tonic inhibition and excitation of interneurons. Nat. Neurosci. 2010, 13:205-212.
    • (2010) Nat. Neurosci. , vol.13 , pp. 205-212
    • Mann, E.O.1    Mody, I.2
  • 39
    • 77950981525 scopus 로고    scopus 로고
    • Alpha5GABAA receptor activity sets the threshold for long-term potentiation and constrains hippocampus-dependent memory
    • Martin L.J., Zurek A.A., MacDonald J.F., Roder J.C., Jackson M.F., Orser B.A. Alpha5GABAA receptor activity sets the threshold for long-term potentiation and constrains hippocampus-dependent memory. J. Neurosci. 2010, 30:5269-5282.
    • (2010) J. Neurosci. , vol.30 , pp. 5269-5282
    • Martin, L.J.1    Zurek, A.A.2    MacDonald, J.F.3    Roder, J.C.4    Jackson, M.F.5    Orser, B.A.6
  • 40
    • 0017132898 scopus 로고
    • Schizophrenic psychology, associative learning and the role of forebrain dopamine
    • Miller R. Schizophrenic psychology, associative learning and the role of forebrain dopamine. Med. Hypotheses 1976, 2:203-211.
    • (1976) Med. Hypotheses , vol.2 , pp. 203-211
    • Miller, R.1
  • 43
    • 0028850552 scopus 로고
    • Glutamate receptor dysfunction and schizophrenia
    • Olney J.W., Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch. Gen. Psychiatry 1995, 52:998-1007.
    • (1995) Arch. Gen. Psychiatry , vol.52 , pp. 998-1007
    • Olney, J.W.1    Farber, N.B.2
  • 44
    • 33745437702 scopus 로고    scopus 로고
    • The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour
    • Pocklington A.J., Cumiskey M., Armstrong J.D., Grant S.G. The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour. Mol. Syst. Biol. 2006, 2. 10.1038/msb4100041.
    • (2006) Mol. Syst. Biol. , vol.2
    • Pocklington, A.J.1    Cumiskey, M.2    Armstrong, J.D.3    Grant, S.G.4
  • 47
    • 78049450213 scopus 로고    scopus 로고
    • Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function
    • International Schizophrenia Consortium
    • Raychaudhuri S., Korn J.M., McCarroll S.A., Altshuler D., Sklar P., Purcell S., Daly M.J. Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. PLoS Genet. 2010, 6:e1001097. International Schizophrenia Consortium.
    • (2010) PLoS Genet. , vol.6 , pp. e1001097
    • Raychaudhuri, S.1    Korn, J.M.2    McCarroll, S.A.3    Altshuler, D.4    Sklar, P.5    Purcell, S.6    Daly, M.J.7
  • 50
    • 0015422513 scopus 로고
    • Prospects for research on schizophrenia. An hypotheses suggesting that there is a defect in the GABA system in schizophrenia
    • Roberts E. Prospects for research on schizophrenia. An hypotheses suggesting that there is a defect in the GABA system in schizophrenia. Neurosci. Res. Program Bull. 1972, 10:468-482.
    • (1972) Neurosci. Res. Program Bull. , vol.10 , pp. 468-482
    • Roberts, E.1
  • 51
    • 0035449320 scopus 로고    scopus 로고
    • Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning
    • Rodrigues S.M., Schafe G.E., LeDoux J.E. Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning. J. Neurosci. 2001, 21:6889-6896.
    • (2001) J. Neurosci. , vol.21 , pp. 6889-6896
    • Rodrigues, S.M.1    Schafe, G.E.2    LeDoux, J.E.3
  • 53
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium
    • Biological insights from 108 schizophrenia-associated genetic loci. Nature 2014, 511:421-427. Schizophrenia Working Group of the Psychiatric Genomics Consortium.
    • (2014) Nature , vol.511 , pp. 421-427
  • 55
    • 65349122415 scopus 로고    scopus 로고
    • Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring
    • Stephan K.E., Friston K.J., Frith C.D. Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring. Schizophr. Bull. 2009, 35:509-527.
    • (2009) Schizophr. Bull. , vol.35 , pp. 509-527
    • Stephan, K.E.1    Friston, K.J.2    Frith, C.D.3
  • 56
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: the emerging picture and its implications
    • Sullivan P.F., Daly M.J., O'Donovan M. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat. Rev. Genet. 2012, 13:537-551.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3
  • 58
    • 75649088570 scopus 로고    scopus 로고
    • Abnormal neural oscillations and synchrony in schizophrenia
    • Uhlhaas P.J., Singer W. Abnormal neural oscillations and synchrony in schizophrenia. Nat. Rev. Neurosci. 2010, 11:100-113.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 100-113
    • Uhlhaas, P.J.1    Singer, W.2
  • 60
    • 35948984173 scopus 로고    scopus 로고
    • PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
    • Wang K., Li M., Hadley D., Liu R., Glessner J., Grant S.F., Hakonarson H., Bucan M. PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Res. 2007, 17:1665-1674.
    • (2007) Genome Res. , vol.17 , pp. 1665-1674
    • Wang, K.1    Li, M.2    Hadley, D.3    Liu, R.4    Glessner, J.5    Grant, S.F.6    Hakonarson, H.7    Bucan, M.8
  • 62
    • 0037067242 scopus 로고    scopus 로고
    • The human gamma-aminobutyric acid A receptor delta (GABRD) gene: molecular characterisation and tissue-specific expression
    • Windpassinger C., Kroisel P.M., Wagner K., Petek E. The human gamma-aminobutyric acid A receptor delta (GABRD) gene: molecular characterisation and tissue-specific expression. Gene 2002, 292:25-31.
    • (2002) Gene , vol.292 , pp. 25-31
    • Windpassinger, C.1    Kroisel, P.M.2    Wagner, K.3    Petek, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.