Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations

Hepatology

Volumn 54, Issue 4, 2011, Pages 1157-1166

  Neumann Haefelin, Christoph ^a,b   Oniangue Ndza, Cesar ^a   Kuntzen, Thomas ^a,c   Schmidt, Julia ^b   Nitschke, Katja ^b   Sidney, John ^d   Caillet Saguy, Célia ^e   Binder, Marco ^f   Kersting, Nadine ^b   Kemper, Michael W ^a   Power, Karen A ^a   Ingber, Susan ^g   Reyor, Laura L ^g   Hills Evans, Kelsey ^g   Kim, Arthur Y ^g   Lauer, Georg M ^g   Lohmann, Volker ^f   Sette, Alessandro ^d   Henn, Matthew R ^h   Bressanelli, Stéphane ^e   Thimme, Robert ^b   Allen, Todd M ^a   more..

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^e CNRS   (France)

^f UNIVERSITY OF HEIDELBERG   (Germany)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

^h BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HLA B27 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; GENE MUTATION; GENE SEQUENCE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; IMMUNOREGULATION; LIVER PROTECTION; NONHUMAN; PRIORITY JOURNAL; VIRUS GENOME; VIRUS REPLICATION;

BINDING SITES; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES, T-LYMPHOCYTE; HEPACIVIRUS; HEPATITIS C; HLA-B27 ANTIGEN; HUMANS; IMMUNODOMINANT EPITOPES; MUTATION; SAMPLING STUDIES; SENSITIVITY AND SPECIFICITY; VIRUS REPLICATION;

EID: 80053316319     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24541     Document Type: Article

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