메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages

Mice lacking the PSD-95-interacting E3 ligase, Dorfin/Rnf19a, display reduced adult neurogenesis, enhanced long-term potentiation, and impaired contextual fear conditioning

Author keywords

[No Author keywords available]

Indexed keywords

DLGH4 PROTEIN, MOUSE; GUANYLATE KINASE; MEMBRANE PROTEIN; PROTEIN BINDING; PROTEOME; RNF19A PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

EID: 84946950124     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16410     Document Type: Article
Times cited : (26)

References (89)
  • 1
    • 54249158324 scopus 로고    scopus 로고
    • Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction
    • Tai, H. C. & Schuman, E. M. Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction. Nat Rev Neurosci 9, 826-838 (2008).
    • (2008) Nat Rev Neurosci , vol.9 , pp. 826-838
    • Tai, H.C.1    Schuman, E.M.2
  • 2
    • 78650962524 scopus 로고    scopus 로고
    • Deconstruction for reconstruction: The role of proteolysis in neural plasticity and disease
    • Bingol, B. & Sheng, M. Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease. Neuron 69, 22-32 (2011).
    • (2011) Neuron , vol.69 , pp. 22-32
    • Bingol, B.1    Sheng, M.2
  • 3
    • 79955049275 scopus 로고    scopus 로고
    • The role of ubiquitylation in nerve cell development
    • Kawabe, H. & Brose, N. The role of ubiquitylation in nerve cell development. Nat Rev Neurosci 12, 251-268 (2011).
    • (2011) Nat Rev Neurosci , vol.12 , pp. 251-268
    • Kawabe, H.1    Brose, N.2
  • 4
    • 78049395303 scopus 로고    scopus 로고
    • Ubiquitination in postsynaptic function and plasticity
    • Mabb, A. M. & Ehlers, M. D. Ubiquitination in postsynaptic function and plasticity. Annu Rev Cell Dev Biol 26, 179-210 (2010).
    • (2010) Annu Rev Cell Dev Biol , vol.26 , pp. 179-210
    • Mabb, A.M.1    Ehlers, M.D.2
  • 5
    • 84875853339 scopus 로고    scopus 로고
    • Spatial organization of ubiquitin ligase pathways orchestrates neuronal connectivity
    • Yamada, T., Yang, Y. & Bonni, A. Spatial organization of ubiquitin ligase pathways orchestrates neuronal connectivity. Trends Neurosci 36, 218-226 (2013).
    • (2013) Trends Neurosci , vol.36 , pp. 218-226
    • Yamada, T.1    Yang, Y.2    Bonni, A.3
  • 6
    • 0345119031 scopus 로고    scopus 로고
    • Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression
    • Colledge, M. et al. Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron 40, 595-607 (2003).
    • (2003) Neuron , vol.40 , pp. 595-607
    • Colledge, M.1
  • 7
    • 0037374587 scopus 로고    scopus 로고
    • Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system
    • Ehlers, M. D. Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system. Nat Neurosci 6, 231-242 (2003).
    • (2003) Nat Neurosci , vol.6 , pp. 231-242
    • Ehlers, M.D.1
  • 8
    • 78149460672 scopus 로고    scopus 로고
    • Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons
    • Hung, A. Y., Sung, C. C., Brito, I. L. & Sheng, M. Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons. PLoS One 5, e9842 (2010).
    • (2010) PLoS One , vol.5 , pp. e9842
    • Hung, A.Y.1    Sung, C.C.2    Brito, I.L.3    Sheng, M.4
  • 9
    • 0344443828 scopus 로고    scopus 로고
    • Targeted protein degradation and synapse remodeling by an inducible protein kinase
    • Pak, D. T. & Sheng, M. Targeted protein degradation and synapse remodeling by an inducible protein kinase. Science 302, 1368-1373 (2003).
    • (2003) Science , vol.302 , pp. 1368-1373
    • Pak, D.T.1    Sheng, M.2
  • 10
    • 57649165427 scopus 로고    scopus 로고
    • Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons
    • Ang, X. L., Seeburg, D. P., Sheng, M. & Harper, J. W. Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons. J Biol Chem 283, 29424-29432 (2008).
    • (2008) J Biol Chem , vol.283 , pp. 29424-29432
    • Ang, X.L.1    Seeburg, D.P.2    Sheng, M.3    Harper, J.W.4
  • 11
    • 0035844262 scopus 로고    scopus 로고
    • Regulation of the level of Vesl-1S/Homer-1a proteins by ubiquitin-proteasome proteolytic systems
    • Ageta, H. et al. Regulation of the level of Vesl-1S/Homer-1a proteins by ubiquitin-proteasome proteolytic systems. J Biol Chem 276, 15893-15897 (2001).
    • (2001) J Biol Chem , vol.276 , pp. 15893-15897
    • Ageta, H.1
  • 12
    • 84866108712 scopus 로고    scopus 로고
    • Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis
    • Na, C. H. et al. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. J Proteome Res 11, 4722-4732 (2012).
    • (2012) J Proteome Res , vol.11 , pp. 4722-4732
    • Na, C.H.1
  • 13
    • 34047107208 scopus 로고    scopus 로고
    • Liprinalpha1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development
    • Hoogenraad, C. C. et al. Liprinalpha1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development. Dev Cell 12, 587-602 (2007).
    • (2007) Dev Cell , vol.12 , pp. 587-602
    • Hoogenraad, C.C.1
  • 14
    • 8844276742 scopus 로고    scopus 로고
    • Independent regulation of synaptic size and activity by the anaphase-promoting complex
    • van Roessel, P., Elliott, D. A., Robinson, I. M., Prokop, A. & Brand, A. H. Independent regulation of synaptic size and activity by the anaphase-promoting complex. Cell 119, 707-718 (2004).
    • (2004) Cell , vol.119 , pp. 707-718
    • Van Roessel, P.1    Elliott, D.A.2    Robinson, I.M.3    Prokop, A.4    Brand, A.H.5
  • 15
    • 77958487953 scopus 로고    scopus 로고
    • EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation
    • Margolis, S. S. et al. EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell 143, 442-455 (2010).
    • (2010) Cell , vol.143 , pp. 442-455
    • Margolis, S.S.1
  • 16
    • 77649083119 scopus 로고    scopus 로고
    • The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc
    • Greer, P. L. et al. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell 140, 704-716 (2010).
    • (2010) Cell , vol.140 , pp. 704-716
    • Greer, P.L.1
  • 17
    • 84902455651 scopus 로고    scopus 로고
    • Triad3A regulates synaptic strength by ubiquitination of Arc
    • Mabb, A. M. et al. Triad3A regulates synaptic strength by ubiquitination of Arc. Neuron 82, 1299-1316 (2014).
    • (2014) Neuron , vol.82 , pp. 1299-1316
    • Mabb, A.M.1
  • 18
    • 9244263049 scopus 로고    scopus 로고
    • The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. Elegans
    • Juo, P. & Kaplan, J. M. The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans. Curr Biol 14, 2057-2062 (2004).
    • (2004) Curr Biol , vol.14 , pp. 2057-2062
    • Juo, P.1    Kaplan, J.M.2
  • 19
    • 79251584863 scopus 로고    scopus 로고
    • APC(Cdh1) mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity
    • Fu, A. K. et al. APC(Cdh1) mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity. Nat Neurosci 14, 181-189 (2011).
    • (2011) Nat Neurosci , vol.14 , pp. 181-189
    • Fu, A.K.1
  • 20
    • 84869816037 scopus 로고    scopus 로고
    • Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission
    • Lussier, M. P. et al. Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission. Proc Natl Acad Sci USA 109, 19426-19431 (2012).
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 19426-19431
    • Lussier, M.P.1
  • 21
    • 78650070867 scopus 로고    scopus 로고
    • Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway
    • Schwarz, L. A., Hall, B. J. & Patrick, G. N. Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway. J Neurosci 30, 16718-16729 (2010).
    • (2010) J Neurosci , vol.30 , pp. 16718-16729
    • Schwarz, L.A.1    Hall, B.J.2    Patrick, G.N.3
  • 22
    • 80052690758 scopus 로고    scopus 로고
    • Nedd4-mediated AMPA receptor ubiquitination regulates receptor turnover and trafficking
    • Lin, A. et al. Nedd4-mediated AMPA receptor ubiquitination regulates receptor turnover and trafficking. J Neurochem 119, 27-39 (2011).
    • (2011) J Neurochem , vol.119 , pp. 27-39
    • Lin, A.1
  • 23
    • 17244381176 scopus 로고    scopus 로고
    • Activity-dependent NMDA receptor degradation mediated by retrotranslocation and ubiquitination
    • Kato, A., Rouach, N., Nicoll, R. A. & Bredt, D. S. Activity-dependent NMDA receptor degradation mediated by retrotranslocation and ubiquitination. Proc Natl Acad Sci USA 102, 5600-5605 (2005).
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5600-5605
    • Kato, A.1    Rouach, N.2    Nicoll, R.A.3    Bredt, D.S.4
  • 24
    • 84862229867 scopus 로고    scopus 로고
    • Proteasomal degradation of the metabotropic glutamate receptor 1alpha is mediated by Homer-3 via the proteasomal S8 ATPase: Signal transduction and synaptic transmission
    • Rezvani, K. et al. Proteasomal degradation of the metabotropic glutamate receptor 1alpha is mediated by Homer-3 via the proteasomal S8 ATPase: Signal transduction and synaptic transmission. J Neurochem 122, 24-37 (2012).
    • (2012) J Neurochem , vol.122 , pp. 24-37
    • Rezvani, K.1
  • 25
    • 2942592073 scopus 로고    scopus 로고
    • Seven in absentia homolog 1A mediates ubiquitination and degradation of group 1 metabotropic glutamate receptors
    • Moriyoshi, K. et al. Seven in absentia homolog 1A mediates ubiquitination and degradation of group 1 metabotropic glutamate receptors. Proc Natl Acad Sci USA 101, 8614-8619 (2004).
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8614-8619
    • Moriyoshi, K.1
  • 26
    • 36849047854 scopus 로고    scopus 로고
    • Activity-dependent ubiquitination of GABA(A) receptors regulates their accumulation at synaptic sites
    • Saliba, R. S., Michels, G., Jacob, T. C., Pangalos, M. N. & Moss, S. J. Activity-dependent ubiquitination of GABA(A) receptors regulates their accumulation at synaptic sites. J Neurosci 27, 13341-13351 (2007).
    • (2007) J Neurosci , vol.27 , pp. 13341-13351
    • Saliba, R.S.1    Michels, G.2    Jacob, T.C.3    Pangalos, M.N.4    Moss, S.J.5
  • 27
    • 70350434303 scopus 로고    scopus 로고
    • Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition
    • Arancibia-Carcamo, I. L. et al. Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition. Proc Natl Acad Sci USA 106, 17552-17557 (2009).
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 17552-17557
    • Arancibia-Carcamo, I.L.1
  • 28
    • 77950473954 scopus 로고    scopus 로고
    • Fbxo45, a novel ubiquitin ligase, regulates synaptic activity
    • Tada, H. et al. Fbxo45, a novel ubiquitin ligase, regulates synaptic activity. J Biol Chem 285, 3840-3849 (2010).
    • (2010) J Biol Chem , vol.285 , pp. 3840-3849
    • Tada, H.1
  • 29
    • 34548243126 scopus 로고    scopus 로고
    • SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release
    • Yao, I. et al. SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release. Cell 130, 943-957 (2007).
    • (2007) Cell , vol.130 , pp. 943-957
    • Yao, I.1
  • 30
    • 84875950775 scopus 로고    scopus 로고
    • Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation
    • Waites, C. L. et al. Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation. EMBO J 32, 954-969 (2013).
    • (2013) EMBO J , vol.32 , pp. 954-969
    • Waites, C.L.1
  • 31
    • 0344339019 scopus 로고    scopus 로고
    • XYbp, a novel RING-finger protein, is a component of the XY body of spermatocytes and centrosomes
    • Parraga, M. & del Mazo, J. XYbp, a novel RING-finger protein, is a component of the XY body of spermatocytes and centrosomes. Mech Dev 90, 95-101 (2000).
    • (2000) Mech Dev , vol.90 , pp. 95-101
    • Parraga, M.1    Del Mazo, J.2
  • 32
    • 0034816123 scopus 로고    scopus 로고
    • A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity
    • Niwa, J. et al. A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity. Biochem Biophys Res Commun 281, 706-713 (2001).
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 706-713
    • Niwa, J.1
  • 33
    • 0037184063 scopus 로고    scopus 로고
    • Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity
    • Niwa, J. et al. Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity. J Biol Chem 277, 36793-36798 (2002).
    • (2002) J Biol Chem , vol.277 , pp. 36793-36798
    • Niwa, J.1
  • 34
    • 0041343292 scopus 로고    scopus 로고
    • Dorfin localizes to the ubiquitylated inclusions in Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and amyotrophic lateral sclerosis
    • Hishikawa, N. et al. Dorfin localizes to the ubiquitylated inclusions in Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and amyotrophic lateral sclerosis. Am J Pathol 163, 609-619 (2003).
    • (2003) Am J Pathol , vol.163 , pp. 609-619
    • Hishikawa, N.1
  • 35
    • 0042206574 scopus 로고    scopus 로고
    • Dorfin localizes to Lewy bodies and ubiquitylates synphilin-1
    • Ito, T. et al. Dorfin localizes to Lewy bodies and ubiquitylates synphilin-1. J Biol Chem 278, 29106-29114 (2003).
    • (2003) J Biol Chem , vol.278 , pp. 29106-29114
    • Ito, T.1
  • 36
    • 1842562857 scopus 로고    scopus 로고
    • Dorfin prevents cell death by reducing mitochondrial localizing mutant superoxide dismutase 1 in a neuronal cell model of familial amyotrophic lateral sclerosis
    • Takeuchi, H. et al. Dorfin prevents cell death by reducing mitochondrial localizing mutant superoxide dismutase 1 in a neuronal cell model of familial amyotrophic lateral sclerosis. J Neurochem 89, 64-72 (2004).
    • (2004) J Neurochem , vol.89 , pp. 64-72
    • Takeuchi, H.1
  • 37
    • 10944247870 scopus 로고    scopus 로고
    • Physical and functional interaction between Dorfin and Valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders
    • Ishigaki, S. et al. Physical and functional interaction between Dorfin and Valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders. J Biol Chem 279, 51376-51385 (2004).
    • (2004) J Biol Chem , vol.279 , pp. 51376-51385
    • Ishigaki, S.1
  • 38
    • 34948850962 scopus 로고    scopus 로고
    • Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1
    • Niwa, J. et al. Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1. J Biol Chem 282, 28087-28095 (2007).
    • (2007) J Biol Chem , vol.282 , pp. 28087-28095
    • Niwa, J.1
  • 39
    • 33846297722 scopus 로고    scopus 로고
    • Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity
    • Ishigaki, S. et al. Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity. Neurobiol Dis 25, 331-341 (2007).
    • (2007) Neurobiol Dis , vol.25 , pp. 331-341
    • Ishigaki, S.1
  • 40
    • 73949087427 scopus 로고    scopus 로고
    • Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis
    • Sone, J. et al. Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci Res 88, 123-135 (2010).
    • (2010) J Neurosci Res , vol.88 , pp. 123-135
    • Sone, J.1
  • 41
    • 34447331941 scopus 로고    scopus 로고
    • Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network
    • McHugh, T. J. et al. Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network. Science 317, 94-99 (2007).
    • (2007) Science , vol.317 , pp. 94-99
    • McHugh, T.J.1
  • 42
    • 84862898508 scopus 로고    scopus 로고
    • NR2B-dependent plasticity of adult-born granule cells is necessary for context discrimination
    • Kheirbek, M. A., Tannenholz, L. & Hen, R. NR2B-dependent plasticity of adult-born granule cells is necessary for context discrimination. J Neurosci 32, 8696-8702 (2012).
    • (2012) J Neurosci , vol.32 , pp. 8696-8702
    • Kheirbek, M.A.1    Tannenholz, L.2    Hen, R.3
  • 43
    • 33846461062 scopus 로고    scopus 로고
    • Morris water maze: Procedures for assessing spatial and related forms of learning and memory
    • Vorhees, C. V. & Williams, M. T. Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat Protoc 1, 848-858 (2006).
    • (2006) Nat Protoc , vol.1 , pp. 848-858
    • Vorhees, C.V.1    Williams, M.T.2
  • 44
    • 33947668266 scopus 로고    scopus 로고
    • T-maze alternation in the rodent
    • Deacon, R. M. & Rawlins, J. N. T-maze alternation in the rodent. Nat Protoc 1, 7-12 (2006).
    • (2006) Nat Protoc , vol.1 , pp. 7-12
    • Deacon, R.M.1    Rawlins, J.N.2
  • 45
    • 84891351389 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian hippocampus: Why the dentate gyrus?
    • Drew, L. J., Fusi, S. & Hen, R. Adult neurogenesis in the mammalian hippocampus: why the dentate gyrus? Learn Mem 20, 710-729 (2013).
    • (2013) Learn Mem , vol.20 , pp. 710-729
    • Drew, L.J.1    Fusi, S.2    Hen, R.3
  • 46
    • 84875083828 scopus 로고    scopus 로고
    • The operation of pattern separation and pattern completion processes associated with different attributes or domains of memory
    • Hunsaker, M. R. & Kesner, R. P. The operation of pattern separation and pattern completion processes associated with different attributes or domains of memory. Neurosci Biobehav Rev 37, 36-58 (2013).
    • (2013) Neurosci Biobehav Rev , vol.37 , pp. 36-58
    • Hunsaker, M.R.1    Kesner, R.P.2
  • 47
    • 67650450542 scopus 로고    scopus 로고
    • A functional role for adult hippocampal neurogenesis in spatial pattern separation
    • Clelland, C. D. et al. A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 325, 210-213 (2009).
    • (2009) Science , vol.325 , pp. 210-213
    • Clelland, C.D.1
  • 48
    • 39249084254 scopus 로고    scopus 로고
    • Synaptic adhesion molecules and PSD-95
    • Han, K. & Kim, E. Synaptic adhesion molecules and PSD-95. Prog Neurobiol 84, 263-283 (2008).
    • (2008) Prog Neurobiol , vol.84 , pp. 263-283
    • Han, K.1    Kim, E.2
  • 49
    • 84862996059 scopus 로고    scopus 로고
    • The postsynaptic organization of synapses
    • Sheng, M. & Kim, E. The postsynaptic organization of synapses. Cold Spring Harb Perspect Biol 3, a005678 (2011).
    • (2011) Cold Spring Harb Perspect Biol , vol.3 , pp. a005678
    • Sheng, M.1    Kim, E.2
  • 50
    • 0037016687 scopus 로고    scopus 로고
    • Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain
    • Fallon, L. et al. Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. J Biol Chem 277, 486-491 (2002).
    • (2002) J Biol Chem , vol.277 , pp. 486-491
    • Fallon, L.1
  • 51
    • 58049209715 scopus 로고    scopus 로고
    • Pruning and loss of excitatory synapses by the parkin ubiquitin ligase
    • Helton, T. D., Otsuka, T., Lee, M. C., Mu, Y. & Ehlers, M. D. Pruning and loss of excitatory synapses by the parkin ubiquitin ligase. Proc Natl Acad Sci USA 105, 19492-19497 (2008).
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19492-19497
    • Helton, T.D.1    Otsuka, T.2    Lee, M.C.3    Mu, Y.4    Ehlers, M.D.5
  • 52
    • 0037422010 scopus 로고    scopus 로고
    • Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
    • Staropoli, J. F. et al. Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron 37, 735-749 (2003).
    • (2003) Neuron , vol.37 , pp. 735-749
    • Staropoli, J.F.1
  • 53
    • 84863471483 scopus 로고    scopus 로고
    • Molecular organization and plasticity of the cytomatrix at the active zone
    • Gundelfinger, E. D. & Fejtova, A. Molecular organization and plasticity of the cytomatrix at the active zone. Curr Opin Neurobiol 22, 423-430 (2012).
    • (2012) Curr Opin Neurobiol , vol.22 , pp. 423-430
    • Gundelfinger, E.D.1    Fejtova, A.2
  • 54
    • 84863496238 scopus 로고    scopus 로고
    • Posttranslational regulation of AMPA receptor trafficking and function
    • Lu, W. & Roche, K. W. Posttranslational regulation of AMPA receptor trafficking and function. Curr Opin Neurobiol 22, 470-479 (2012).
    • (2012) Curr Opin Neurobiol , vol.22 , pp. 470-479
    • Lu, W.1    Roche, K.W.2
  • 55
    • 84912532471 scopus 로고    scopus 로고
    • The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity
    • Chater, T. E. & Goda, Y. The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity. Front Cell Neurosci 8, 401 (2014).
    • (2014) Front Cell Neurosci , vol.8 , pp. 401
    • Chater, T.E.1    Goda, Y.2
  • 56
    • 0032192481 scopus 로고    scopus 로고
    • Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation
    • Jiang, Y. H. et al. Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Neuron 21, 799-811 (1998).
    • (1998) Neuron , vol.21 , pp. 799-811
    • Jiang, Y.H.1
  • 57
    • 79953296182 scopus 로고    scopus 로고
    • Control of PKA stability and signalling by the RING ligase praja2
    • Lignitto, L. et al. Control of PKA stability and signalling by the RING ligase praja2. Nat Cell Biol 13, 412-422 (2011).
    • (2011) Nat Cell Biol , vol.13 , pp. 412-422
    • Lignitto, L.1
  • 58
    • 84867900905 scopus 로고    scopus 로고
    • Mind bomb-1 is an essential modulator of long-term memory and synaptic plasticity via the Notch signaling pathway
    • Yoon, K. J. et al. Mind bomb-1 is an essential modulator of long-term memory and synaptic plasticity via the Notch signaling pathway. Mol Brain 5, 40 (2012).
    • (2012) Mol Brain , vol.5 , pp. 40
    • Yoon, K.J.1
  • 59
    • 84871831029 scopus 로고    scopus 로고
    • Neuronal expression of the ubiquitin E3 ligase APC/C-Cdh1 during development is required for long-term potentiation, behavioral flexibility, and extinction
    • Pick, J. E., Wang, L., Mayfield, J. E. & Klann, E. Neuronal expression of the ubiquitin E3 ligase APC/C-Cdh1 during development is required for long-term potentiation, behavioral flexibility, and extinction. Neurobiol Learn Mem 100, 25-31 (2013).
    • (2013) Neurobiol Learn Mem , vol.100 , pp. 25-31
    • Pick, J.E.1    Wang, L.2    Mayfield, J.E.3    Klann, E.4
  • 60
    • 51049088378 scopus 로고    scopus 로고
    • The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory
    • Li, M. et al. The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. Nat Cell Biol 10, 1083-1089 (2008).
    • (2008) Nat Cell Biol , vol.10 , pp. 1083-1089
    • Li, M.1
  • 61
    • 84872159985 scopus 로고    scopus 로고
    • SCRAPPER regulates the thresholds of long-term potentiation/depression, the bidirectional synaptic plasticity in hippocampal CA3-CA1 synapses
    • Takagi, H., Setou, M., Ito, S. & Yao, I. SCRAPPER regulates the thresholds of long-term potentiation/depression, the bidirectional synaptic plasticity in hippocampal CA3-CA1 synapses. Neural Plast 2012, 352829 (2012).
    • (2012) Neural Plast , vol.2012 , pp. 352829
    • Takagi, H.1    Setou, M.2    Ito, S.3    Yao, I.4
  • 62
    • 79952091055 scopus 로고    scopus 로고
    • Synaptic E3 ligase SCRAPPER in contextual fear conditioning: Extensive behavioral phenotyping of Scrapper heterozygote and overexpressing mutant mice
    • Yao, I., Takao, K., Miyakawa, T., Ito, S. & Setou, M. Synaptic E3 ligase SCRAPPER in contextual fear conditioning: extensive behavioral phenotyping of Scrapper heterozygote and overexpressing mutant mice. PLoS One 6, e17317 (2011).
    • (2011) PLoS One , vol.6 , pp. e17317
    • Yao, I.1    Takao, K.2    Miyakawa, T.3    Ito, S.4    Setou, M.5
  • 64
    • 33751213392 scopus 로고    scopus 로고
    • Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus
    • Saxe, M. D. et al. Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proc Natl Acad Sci USA 103, 17501-17506 (2006).
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17501-17506
    • Saxe, M.D.1
  • 65
    • 33644507720 scopus 로고    scopus 로고
    • Adult neurogenesis and functional plasticity in neuronal circuits
    • Lledo, P. M., Alonso, M. & Grubb, M. S. Adult neurogenesis and functional plasticity in neuronal circuits. Nat Rev Neurosci 7, 179-193 (2006).
    • (2006) Nat Rev Neurosci , vol.7 , pp. 179-193
    • Lledo, P.M.1    Alonso, M.2    Grubb, M.S.3
  • 66
    • 84871830491 scopus 로고    scopus 로고
    • The E3 ligase APC/C-Cdh1 is required for associative fear memory and long-term potentiation in the amygdala of adult mice
    • Pick, J. E., Malumbres, M. & Klann, E. The E3 ligase APC/C-Cdh1 is required for associative fear memory and long-term potentiation in the amygdala of adult mice. Learn Mem 20, 11-20 (2013).
    • (2013) Learn Mem , vol.20 , pp. 11-20
    • Pick, J.E.1    Malumbres, M.2    Klann, E.3
  • 67
    • 67649479622 scopus 로고    scopus 로고
    • Impaired dopamine release and synaptic plasticity in the striatum of parkin-/- mice
    • Kitada, T. et al. Impaired dopamine release and synaptic plasticity in the striatum of parkin-/- mice. J Neurochem 110, 613-621 (2009).
    • (2009) J Neurochem , vol.110 , pp. 613-621
    • Kitada, T.1
  • 68
    • 67349178189 scopus 로고    scopus 로고
    • Ube3a is required for experience-dependent maturation of the neocortex
    • Yashiro, K. et al. Ube3a is required for experience-dependent maturation of the neocortex. Nat Neurosci 12, 777-783 (2009).
    • (2009) Nat Neurosci , vol.12 , pp. 777-783
    • Yashiro, K.1
  • 69
    • 0347224273 scopus 로고    scopus 로고
    • Removal of G(ialpha1) constraints on adenylyl cyclase in the hippocampus enhances LTP and impairs memory formation
    • Pineda, V. V. et al. Removal of G(ialpha1) constraints on adenylyl cyclase in the hippocampus enhances LTP and impairs memory formation. Neuron 41, 153-163 (2004).
    • (2004) Neuron , vol.41 , pp. 153-163
    • Pineda, V.V.1
  • 70
    • 0036549187 scopus 로고    scopus 로고
    • Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice
    • Gu, Y. et al. Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice. J Neurosci 22, 2753-2763 (2002).
    • (2002) J Neurosci , vol.22 , pp. 2753-2763
    • Gu, Y.1
  • 71
    • 47849119785 scopus 로고    scopus 로고
    • Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D) mice
    • Rutten, K. et al. Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D) mice. Eur J Neurosci 28, 625-632 (2008).
    • (2008) Eur J Neurosci , vol.28 , pp. 625-632
    • Rutten, K.1
  • 72
    • 59649118111 scopus 로고    scopus 로고
    • Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53
    • Kim, M. H. et al. Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53. J Neurosci 29, 1586-1595 (2009).
    • (2009) J Neurosci , vol.29 , pp. 1586-1595
    • Kim, M.H.1
  • 73
    • 66149124468 scopus 로고    scopus 로고
    • The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity
    • Sawallisch, C. et al. The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem 284, 9225-9236 (2009).
    • (2009) J Biol Chem , vol.284 , pp. 9225-9236
    • Sawallisch, C.1
  • 74
    • 41149119949 scopus 로고    scopus 로고
    • Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation
    • Correia, S. S. et al. Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation. Nat Neurosci 11, 457-466 (2008).
    • (2008) Nat Neurosci , vol.11 , pp. 457-466
    • Correia, S.S.1
  • 75
    • 54549123514 scopus 로고    scopus 로고
    • Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity
    • Wang, Z. et al. Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity. Cell 135, 535-548 (2008).
    • (2008) Cell , vol.135 , pp. 535-548
    • Wang, Z.1
  • 76
    • 68349117289 scopus 로고    scopus 로고
    • Endocytic trafficking and recycling maintain a pool of mobile surface AMPA receptors required for synaptic potentiation
    • Petrini, E. M. et al. Endocytic trafficking and recycling maintain a pool of mobile surface AMPA receptors required for synaptic potentiation. Neuron 63, 92-105 (2009).
    • (2009) Neuron , vol.63 , pp. 92-105
    • Petrini, E.M.1
  • 77
  • 78
    • 84899431011 scopus 로고    scopus 로고
    • 14-3-3 proteins are required for hippocampal long-term potentiation and associative learning and memory
    • Qiao, H., Foote, M., Graham, K., Wu, Y. & Zhou, Y. 14-3-3 proteins are required for hippocampal long-term potentiation and associative learning and memory. J Neurosci 34, 4801-4808 (2014).
    • (2014) J Neurosci , vol.34 , pp. 4801-4808
    • Qiao, H.1    Foote, M.2    Graham, K.3    Wu, Y.4    Zhou, Y.5
  • 79
    • 79956209852 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian brain: Significant answers and significant questions
    • Ming, G. L. & Song, H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 70, 687-702 (2011).
    • (2011) Neuron , vol.70 , pp. 687-702
    • Ming, G.L.1    Song, H.2
  • 80
    • 79955639851 scopus 로고    scopus 로고
    • Conditional reduction of adult neurogenesis impairs bidirectional hippocampal synaptic plasticity
    • Massa, F. et al. Conditional reduction of adult neurogenesis impairs bidirectional hippocampal synaptic plasticity. Proc Natl Acad Sci USA 108, 6644-6649 (2011).
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 6644-6649
    • Massa, F.1
  • 81
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory?
    • Deng, W., Aimone, J. B. & Gage, F. H. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci 11, 339-350 (2010).
    • (2010) Nat Rev Neurosci , vol.11 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 82
    • 77958523924 scopus 로고    scopus 로고
    • Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins
    • Oh, D. et al. Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. J Neurosci 30, 14134-14144 (2010).
    • (2010) J Neurosci , vol.30 , pp. 14134-14144
    • Oh, D.1
  • 83
    • 0037023742 scopus 로고    scopus 로고
    • Phosphorylation of stargazin by protein kinase A regulates its interaction with PSD-95
    • Choi, J. et al. Phosphorylation of stargazin by protein kinase A regulates its interaction with PSD-95. J Biol Chem 277, 12359-12363 (2002).
    • (2002) J Biol Chem , vol.277 , pp. 12359-12363
    • Choi, J.1
  • 84
    • 0036662882 scopus 로고    scopus 로고
    • Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapseassociated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins
    • Mok, H. et al. Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapseassociated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins. J Neurosci 22, 5253-5258 (2002).
    • (2002) J Neurosci , vol.22 , pp. 5253-5258
    • Mok, H.1
  • 85
    • 84862297282 scopus 로고    scopus 로고
    • Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
    • Won, H. et al. Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 486, 261-265 (2012).
    • (2012) Nature , vol.486 , pp. 261-265
    • Won, H.1
  • 86
    • 0037805671 scopus 로고    scopus 로고
    • The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42
    • Park, E. et al. The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42. J Biol Chem 278, 19220-19229 (2003).
    • (2003) J Biol Chem , vol.278 , pp. 19220-19229
    • Park, E.1
  • 87
    • 0028882810 scopus 로고
    • Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases
    • Kim, E., Niethammer, M., Rothschild, A., Jan, Y. N. & Sheng, M. Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases. Nature 378, 85-88 (1995).
    • (1995) Nature , vol.378 , pp. 85-88
    • Kim, E.1    Niethammer, M.2    Rothschild, A.3    Jan, Y.N.4    Sheng, M.5
  • 88
    • 0020955120 scopus 로고
    • Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation
    • Huttner, W. B., Schiebler, W., Greengard, P. & De Camilli, P. Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J Cell Biol 96, 1374-1388 (1983).
    • (1983) J Cell Biol , vol.96 , pp. 1374-1388
    • Huttner, W.B.1    Schiebler, W.2    Greengard, P.3    De Camilli, P.4
  • 89
    • 77953800799 scopus 로고    scopus 로고
    • Behavioural phenotyping assays for mouse models of autism
    • Silverman, J. L., Yang, M., Lord, C. & Crawley, J. N. Behavioural phenotyping assays for mouse models of autism. Nat Rev Neurosci 11, 490-502 (2010).
    • (2010) Nat Rev Neurosci , vol.11 , pp. 490-502
    • Silverman, J.L.1    Yang, M.2    Lord, C.3    Crawley, J.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.