Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

Nature

Volumn 486, Issue 7402, 2012, Pages 261-265

  Won, Hyejung ^a   Lee, Hye Ryeon ^b   Gee, Heon Yung ^c   Mah, Won ^a   Kim, Jae Ick ^b   Lee, Jiseok ^a   Ha, Seungmin ^a   Chung, Changuk ^a   Jung, Eun Suk ^c   Cho, Yi Sul ^d   Park, Sae Geun ^a   Lee, Jung Soo ^c   Lee, Kyungmin ^e   Kim, Daesoo ^a   Bae, Yong Chul ^d   Kaang, Bong Kiun ^b   Lee, Min Goo ^c   Kim, Eunjoon ^a,f  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Seoul National University   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d Kyungpook National University   (South Korea)

^e Kyungpook National University School of Medicine   (South Korea)

^f Institute for Basic Science   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSERINE; METABOTROPIC RECEPTOR 5; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

MUTATION; NEUROLOGY; PHENOTYPE; PROTEIN; RODENT; SIGNALING; SOCIAL BEHAVIOR; VOCALIZATION;

ALLOSTERISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; CONTROLLED STUDY; GENE; GENE DELETION; GENE MUTATION; INTERPERSONAL COMMUNICATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SHANK2 GENE; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SOCIOPATHY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIMETABOLITES; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; BENZAMIDES; CYCLOSERINE; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; PYRAZOLES; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84862297282     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11208     Document Type: Article

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