A novel centrosomal RING-finger protein, Dorfin, mediates ubiquitin ligase activity

Biochemical and Biophysical Research Communications

Volumn 281, Issue 3, 2001, Pages 706-713

  Niwa, Jun ichi ^a   Ishigaki, Shinsuke ^a   Doyu, Manabu ^a   Suzuki, Toshiaki ^b   Tanaka, Keiji ^b   Sobue, Gen ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Aggresome; Centrosome; Dorfin; Human; Microtubule organizing center (MTOC); RING finger IBR; Spinal cord; Ubiquitin ligase

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CELL PROTEIN; DORFIN; GENE PRODUCT; LIGASE; MESSENGER RNA; UBIQUITIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CENTROSOME; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DELETION; GENE EXPRESSION; GENE LOCATION; HUMAN; HUMAN CELL; MICROTUBULE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; SPINAL CORD;

EID: 0034816123     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4414     Document Type: Article

References (26)

1. The ubiquitin system
2. Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7
3. The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase
4. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
5. One ring to rule a superfamily of E3 ubiquitin ligases
6. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
7. RING for destruction?
8. SCF and Cullin/Ring H2-based ubiquitin ligases
9. RING finger proteins: Mediators of ubiquitin ligase activity
10. The lore of the RINGs: Substrate recognition and catalysis by ubiquitin ligases
11. A novel transactivation domain in parkin
12. Description of the entire mRNA population by a 3′ end cDNA fragment generated by class IIS restriction enzymes
13. Two novel genes, human neugrin and mouse m-neugrin, are upregulated with neuronal differentiation in neuroblastoma cells
14. XYbp, a novel RING-finger protein, is a component of the XY body of spermatocytes and centrosomes
15. The RING finger. A novel protein sequence motif related to the zinc finger
16. The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1
17. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
18. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
19. Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins
20. Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway
21. Analysis of the degradation function of Mdm2
22. A role of microtubules during the formation of cell processes in neuronal and non-neuronal cells
23. Mutations and off-pathway aggregation of proteins
24. Conformational disease
25. Intermediate filaments and ubiquitin: A new thread in the understanding of chronic neurodegenerative diseases
26. Aggresomes: A cellular response to misfolded proteins