Correlations between photodegradation of bisretinoid constituents of retina and dicarbonyl adduct deposition

Journal of Biological Chemistry

Volumn 290, Issue 45, 2015, Pages 27215-27227

  Zhou, Jilin ^a   Ueda, Keiko ^a   Zhao, Jin ^a   Sparrow, Janet R ^a,b  

^a Columbia University ^*  (United States)

^b Department of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; OPHTHALMOLOGY;

AGE-RELATED MACULAR DEGENERATION; BRUCH'S MEMBRANE; MECHANISTIC STUDIES; RETINAL PIGMENT EPITHELIAL;

DEPOSITION;

ADVANCED GLYCATION END PRODUCT; BISRETINOID; CELL ENZYME; COLLAGEN TYPE 4; GELATINASE A; GELATINASE B; GLYOCYLASE 1; GLYOCYLASE 2; GLYOXAL; LIPOFUSCIN; METHYLGLYOXAL; RETINOID; UNCLASSIFIED DRUG; A2-E (N-RETINYLIDENE-N-RETINYLETHANOLAMINE); ABC TRANSPORTER; ABCA4 PROTEIN, MOUSE; ALCOHOL DEHYDROGENASE; RDH8 PROTEIN, MOUSE;

ADULT; AGING; ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BIOACCUMULATION; BRUCH MEMBRANE; CONTROLLED STUDY; CORRELATIONAL STUDY; DICARBONYL ADDUCT DEPOSITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MACULAR DEGENERATION; MOUSE; NONHUMAN; PHOTODEGRADATION; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN CLEAVAGE; PROTEIN CROSS LINKING; PROTEIN METABOLISM; PROTEIN STRUCTURE; RETINA; RISK FACTOR; UPREGULATION; WILD TYPE; ANIMAL; CELL LINE; CHEMISTRY; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; METABOLISM; MUTANT MOUSE STRAIN; PHOTOLYSIS; RADIATION RESPONSE; RETINAL PIGMENT EPITHELIUM;

AGING; ALCOHOL OXIDOREDUCTASES; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BRUCH MEMBRANE; CELL LINE; GLYCOSYLATION END PRODUCTS, ADVANCED; GLYOXAL; HUMANS; LIPOFUSCIN; MACULAR DEGENERATION; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; PHOTOLYSIS; PROTEIN CARBONYLATION; PYRUVALDEHYDE; RETINA; RETINAL PIGMENT EPITHELIUM; RETINOIDS;

EID: 84946761892     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.680363     Document Type: Article

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