Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

Biochemical Journal

Volumn 443, Issue 1, 2012, Pages 213-222

  Xue, Mingzhan ^a   Rabbani, Naila ^a   Momiji, Hiroshi ^a   Imbasi, Precious ^b,e   Anwar, M Maqsud ^a   Kitteringham, Neil ^c   Park, B Kevin ^c   Souma, Tomokazu ^d   Moriguchi, Takashi ^d   Yamamoto, Masayuki ^d   Thornalley, Paul J ^a,b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF ESSEX   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e NIGER DELTA UNIVERSITY   (Nigeria)

Author keywords

DNA damage; Glycation; Glyoxalase; Methylglyoxal; Nrf2; Protein damage

Indexed keywords

GLYOXALASE; GLYOXALASE 1; MESSENGER RNA; METHYLGLYOXAL; PROTEIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRAIN; CELL ADHESION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DNA ADDUCT; ENZYME ACTIVITY; EXON; GENE; GENE EXPRESSION; GLYCATION; HEART; HUMAN; HUMAN CELL; KIDNEY; LIVER; LUNG; MALE; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; TRANSCRIPTION REGULATION; URINARY EXCRETION;

ANIMALS; BASE SEQUENCE; CELL ADHESION; CONSENSUS SEQUENCE; DNA DAMAGE; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, REPORTER; GLYCOSYLATION END PRODUCTS, ADVANCED; HEP G2 CELLS; HUMANS; LACTOYLGLUTATHIONE LYASE; LUCIFERASES, RENILLA; MALE; MICE; MICE, KNOCKOUT; MUTAGENESIS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTEIN BINDING; PYRUVALDEHYDE; RESPONSE ELEMENTS; TRANSCRIPTION, GENETIC;

MAMMALIA; MUS;

EID: 84858307371     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111648     Document Type: Article

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