-
1
-
-
84857122260
-
The susceptibility of the retina to photochemical damage from visible light
-
Hunter JJ, Morgan JI, Merigan WH, Sliney DH, Sparrow JR, Williams DR. The susceptibility of the retina to photochemical damage from visible light. Prog Retin Eye Res. 2012;31:28-42.
-
(2012)
Prog Retin Eye Res.
, vol.31
, pp. 28-42
-
-
Hunter, J.J.1
Morgan, J.I.2
Merigan, W.H.3
Sliney, D.H.4
Sparrow, J.R.5
Williams, D.R.6
-
2
-
-
77249121028
-
Retinal light damage: Mechanisms and protection
-
Organisciak DT, Vaughan DK. Retinal light damage: mechanisms and protection. Prog Retin Eye Res. 2010;29:113-134.
-
(2010)
Prog Retin Eye Res.
, vol.29
, pp. 113-134
-
-
Organisciak, D.T.1
Vaughan, D.K.2
-
3
-
-
0033745481
-
Circadian-dependent retinal light damage in rats
-
Organisciak DT, Darrow RA, Barsalou L, Kutty RK, Wiggert B. Circadian-dependent retinal light damage in rats. Invest Ophthalmol Vis Sci. 2000;41:3694-3701.
-
(2000)
Invest Ophthalmol Vis Sci.
, vol.41
, pp. 3694-3701
-
-
Organisciak, D.T.1
Darrow, R.A.2
Barsalou, L.3
Kutty, R.K.4
Wiggert, B.5
-
4
-
-
0038667900
-
Increased light damage susceptibility at night does not correlate with RPE65 levels and rhodopsin regeneration in rats
-
Beatrice J, Wenzel A, Reme CE, Grimm C. Increased light damage susceptibility at night does not correlate with RPE65 levels and rhodopsin regeneration in rats. Exp Eye Res. 2003; 76:695-700.
-
(2003)
Exp Eye Res.
, vol.76
, pp. 695-700
-
-
Beatrice, J.1
Wenzel, A.2
Reme, C.E.3
Grimm, C.4
-
5
-
-
0031171328
-
Light-induced apoptosis: Differential timing in the retina and pigment epithelium
-
Hafezi F, Marti A, Munz K, Reme CE. Light-induced apoptosis: differential timing in the retina and pigment epithelium. Exp Eye Res. 1997;64:963-970.
-
(1997)
Exp Eye Res.
, vol.64
, pp. 963-970
-
-
Hafezi, F.1
Marti, A.2
Munz, K.3
Reme, C.E.4
-
6
-
-
11144273817
-
Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration
-
Wenzel A, Grimm C, Samardzija M, Reme CE. Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration. Prog Retin Eye Res. 2005;24:275-306.
-
(2005)
Prog Retin Eye Res.
, vol.24
, pp. 275-306
-
-
Wenzel, A.1
Grimm, C.2
Samardzija, M.3
Reme, C.E.4
-
8
-
-
0020584543
-
Action spectrum of retinal light damage in albino rats
-
Williams TP, Howell WL. Action spectrum of retinal light damage in albino rats. Invest Ophthalmol Vis Sci. 1983;24: 285-287.
-
(1983)
Invest Ophthalmol Vis Sci.
, vol.24
, pp. 285-287
-
-
Williams, T.P.1
Howell, W.L.2
-
9
-
-
0017264207
-
Retinal sensitivity to damage from short wavelength light
-
Ham WT, Mueller HA. Retinal sensitivity to damage from short wavelength light. Nature. 1976;260:153-154.
-
(1976)
Nature.
, vol.260
, pp. 153-154
-
-
Ham, W.T.1
Mueller, H.A.2
-
10
-
-
79960563684
-
The action spectrum of photochemical damage to the retina: A review of monochromatic threshold data
-
van Norren D, Gorgels TGMF. The action spectrum of photochemical damage to the retina: a review of monochromatic threshold data. Photochem Photobiol. 2011;87:747-753.
-
(2011)
Photochem Photobiol.
, vol.87
, pp. 747-753
-
-
van Norren, D.1
Gorgels, T.G.M.F.2
-
11
-
-
0034105724
-
Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration
-
Grimm C, Wenzel A, Hafezi F, Yu S, Redmond TM, Reme CE. Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration. Nat Genet. 2000;25:63-66.
-
(2000)
Nat Genet.
, vol.25
, pp. 63-66
-
-
Grimm, C.1
Wenzel, A.2
Hafezi, F.3
Yu, S.4
Redmond, T.M.5
Reme, C.E.6
-
12
-
-
67649363876
-
Involvement of all-transretinal in acute light-induced retinopathy of mice
-
Maeda A, Maeda T, Golczak M, et al. Involvement of all-transretinal in acute light-induced retinopathy of mice. J Biol Chem. 2009;284:15173-15183.
-
(2009)
J Biol Chem.
, vol.284
, pp. 15173-15183
-
-
Maeda, A.1
Maeda, T.2
Golczak, M.3
-
13
-
-
0034125911
-
A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors
-
Danciger M, Matthes MT, Yasamura D, et al. A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors. Mamm Genome. 2000;11: 422-427.
-
(2000)
Mamm Genome.
, vol.11
, pp. 422-427
-
-
Danciger, M.1
Matthes, M.T.2
Yasamura, D.3
-
14
-
-
0035144779
-
The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration
-
Wenzel A, Reme CE, Williams TP, Hafezi F, Grimm C. The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration. J Neurosci. 2001;21:53-58.
-
(2001)
J Neurosci.
, vol.21
, pp. 53-58
-
-
Wenzel, A.1
Reme, C.E.2
Williams, T.P.3
Hafezi, F.4
Grimm, C.5
-
15
-
-
0035852747
-
Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy
-
Sieving PA, Chaudhry P, Kondo M, et al. Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy. Proc Natl Acad Sci U S A. 2001;98:1835-1840.
-
(2001)
Proc Natl Acad Sci U S A.
, vol.98
, pp. 1835-1840
-
-
Sieving, P.A.1
Chaudhry, P.2
Kondo, M.3
-
16
-
-
0035144009
-
Protective effects of halothane anesthesia on retinal light damage: Inhibition of metabolic rhodopsin regeneration
-
Keller GA, Grimm C, Wenzel A, Hafezi F, Reme CE. Protective effects of halothane anesthesia on retinal light damage: inhibition of metabolic rhodopsin regeneration. Invest Ophthalmol Vis Sci. 2001;42:476-480.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 476-480
-
-
Keller, G.A.1
Grimm, C.2
Wenzel, A.3
Hafezi, F.4
Reme, C.E.5
-
17
-
-
0025105978
-
Predisposing factors to lightinduced photoreceptor cell damage: Retinal changes in maturing rats
-
Rapp LM, Tolman BL, Koutz CA, Thum LA. Predisposing factors to lightinduced photoreceptor cell damage: retinal changes in maturing rats. Exp Eye Res. 1990;51:177-184.
-
(1990)
Exp Eye Res.
, vol.51
, pp. 177-184
-
-
Rapp, L.M.1
Tolman, B.L.2
Koutz, C.A.3
Thum, L.A.4
-
18
-
-
0036581094
-
Evidence for a circadian rhythm of susceptibility to retinal light damage
-
Vaughan DK, Nemke JL, Fliesler SJ. Evidence for a circadian rhythm of susceptibility to retinal light damage. Photochem Photobiol. 2002;75:547-553.
-
(2002)
Photochem Photobiol.
, vol.75
, pp. 547-553
-
-
Vaughan, D.K.1
Nemke, J.L.2
Fliesler, S.J.3
-
19
-
-
0036787618
-
Evidence for two apoptotic pathways in light-induced retinal degeneration
-
Hao W, Wenzel A, Obin MS, et al. Evidence for two apoptotic pathways in light-induced retinal degeneration. Nat Genet. 2002;32:254-260.
-
(2002)
Nat Genet.
, vol.32
, pp. 254-260
-
-
Hao, W.1
Wenzel, A.2
Obin, M.S.3
-
20
-
-
0033538438
-
Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice
-
Weng J, Mata NL, Azarian SM, Tzekov RT, Birch DG, Travis GH. Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice. Cell. 1999;98:13-23.
-
(1999)
Cell.
, vol.98
, pp. 13-23
-
-
Weng, J.1
Mata, N.L.2
Azarian, S.M.3
Tzekov, R.T.4
Birch, D.G.5
Travis, G.H.6
-
21
-
-
2942617209
-
Dark adaptation and the retinoid cycle of vision
-
Lamb TD, Pugh EN. Dark adaptation and the retinoid cycle of vision. Prog Retin Eye Res. 2004;23:307-380.
-
(2004)
Prog Retin Eye Res.
, vol.23
, pp. 307-380
-
-
Lamb, T.D.1
Pugh, E.N.2
-
22
-
-
0015221365
-
Comprehensive investigation of the spectroscopy and photochemistry of retinals, I: Theoretical and experimental considerations of absorption spectra
-
Becker RS, Inuzuka K, Balke DE. Comprehensive investigation of the spectroscopy and photochemistry of retinals, I: theoretical and experimental considerations of absorption spectra. J Am Chem Soc. 1971;93:38-42.
-
(1971)
J Am Chem Soc.
, vol.93
, pp. 38-42
-
-
Becker, R.S.1
Inuzuka, K.2
Balke, D.E.3
-
23
-
-
0002467204
-
Light effects on the retina
-
In: Albert DM, Jakobiec FA, eds. Philadelphia, PA: WB Saunders Co
-
Mellerio J. Light effects on the retina. In: Albert DM, Jakobiec FA, eds. Principles and Practice of Ophthalmology: Basic Science. Philadelphia, PA: WB Saunders Co; 1994;1326-1345.
-
(1994)
Principles and Practice of Ophthalmology: Basic Science.
, pp. 1326-1345
-
-
Mellerio, J.1
-
24
-
-
84862654645
-
Lipofuscin and Nretinylidene-N-retinylethanolamine (A2E) accumulate in the retinal pigment epithelium in the absence of light exposure: Their origin is 11-cis retinal
-
Boyer NP, Higbee D, Currin MB, et al. Lipofuscin and Nretinylidene-N-retinylethanolamine (A2E) accumulate in the retinal pigment epithelium in the absence of light exposure: their origin is 11-cis retinal. J Biol Chem. 2012;287:22276-22286.
-
(2012)
J Biol Chem.
, vol.287
, pp. 22276-22286
-
-
Boyer, N.P.1
Higbee, D.2
Currin, M.B.3
-
25
-
-
18044366931
-
RPE lipofuscin and its role in retinal photobiology
-
Sparrow JR, Boulton M. RPE lipofuscin and its role in retinal photobiology. Exp Eye Res. 2005;80:595-606.
-
(2005)
Exp Eye Res.
, vol.80
, pp. 595-606
-
-
Sparrow, J.R.1
Boulton, M.2
-
26
-
-
84862832810
-
A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine
-
Yamamoto K, Yoon KD, Ueda K, Hashimoto M, Sparrow JR. A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine. Invest Ophthalmol Vis Sci. 2011;52:9084-9090.
-
(2011)
Invest Ophthalmol Vis Sci.
, vol.52
, pp. 9084-9090
-
-
Yamamoto, K.1
Yoon, K.D.2
Ueda, K.3
Hashimoto, M.4
Sparrow, J.R.5
-
27
-
-
0032438193
-
Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium
-
Parish CA, Hashimoto M, Nakanishi K, Dillon J, Sparrow JR. Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium. Proc Natl Acad Sci U S A. 1998;95:14609-14613.
-
(1998)
Proc Natl Acad Sci U S A.
, vol.95
, pp. 14609-14613
-
-
Parish, C.A.1
Hashimoto, M.2
Nakanishi, K.3
Dillon, J.4
Sparrow, J.R.5
-
28
-
-
37649001974
-
The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model
-
Kim SR, Jang YP, Jockusch S, Fishkin NE, Turro NJ, Sparrow JR. The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model. Proc Natl Acad Sci U S A. 2007;104:19273-19278.
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, pp. 19273-19278
-
-
Kim, S.R.1
Jang, Y.P.2
Jockusch, S.3
Fishkin, N.E.4
Turro, N.J.5
Sparrow, J.R.6
-
29
-
-
67749135744
-
Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease
-
Wu Y, Fishkin NE, Pande A, Pande J, Sparrow JR. Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease. J Biol Chem. 2009;284: 20155-20166.
-
(2009)
J Biol Chem.
, vol.284
, pp. 20155-20166
-
-
Wu, Y.1
Fishkin, N.E.2
Pande, A.3
Pande, J.4
Sparrow, J.R.5
-
31
-
-
0029097328
-
Blue light-induced reactivity of retinal age pigment: In vitro generation of oxygen-reactive species
-
Rozanowska M, Jarvis-Evans J, Korytowski W, Boulton ME, Burke JM, Sarna T. Blue light-induced reactivity of retinal age pigment: in vitro generation of oxygen-reactive species. J Biol Chem. 1995;270:18825-18830.
-
(1995)
J Biol Chem.
, vol.270
, pp. 18825-18830
-
-
Rozanowska, M.1
Jarvis-Evans, J.2
Korytowski, W.3
Boulton, M.E.4
Burke, J.M.5
Sarna, T.6
-
32
-
-
0027325869
-
Lipofuscin is a photoinducible free radical generator
-
Boulton M, Dontsov A, Jarvis-Evans J, Ostrovsky M, Svistunenko D. Lipofuscin is a photoinducible free radical generator. J Photochem Photobiol B. 1993;19:201-204.
-
(1993)
J Photochem Photobiol B.
, vol.19
, pp. 201-204
-
-
Boulton, M.1
Dontsov, A.2
Jarvis-Evans, J.3
Ostrovsky, M.4
Svistunenko, D.5
-
33
-
-
0033588376
-
The photoreactivity of the retinal age pigment lipofuscin
-
Wassell J, Davies S, Bardsley W, Boulton M. The photoreactivity of the retinal age pigment lipofuscin. J Biol Chem. 1999;274: 23828-23832.
-
(1999)
J Biol Chem.
, vol.274
, pp. 23828-23832
-
-
Wassell, J.1
Davies, S.2
Bardsley, W.3
Boulton, M.4
-
34
-
-
20444418659
-
Blue light induces mitochondrial DNA damage and free radical production in epithelial cells
-
Godley BF, Shamsi FA, Liang FQ, Jarrett SG, Davies S, Boulton M. Blue light induces mitochondrial DNA damage and free radical production in epithelial cells. J Biol Chem. 2005;280: 21061-21066.
-
(2005)
J Biol Chem.
, vol.280
, pp. 21061-21066
-
-
Godley, B.F.1
Shamsi, F.A.2
Liang, F.Q.3
Jarrett, S.G.4
Davies, S.5
Boulton, M.6
-
35
-
-
0000117096
-
Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin
-
Schutt F, Davies S, Kopitz J, Holz FG, Boulton ME. Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin. Invest Ophthalmol Vis Sci. 2000;41:2303-2308.
-
(2000)
Invest Ophthalmol Vis Sci.
, vol.41
, pp. 2303-2308
-
-
Schutt, F.1
Davies, S.2
Kopitz, J.3
Holz, F.G.4
Boulton, M.E.5
-
36
-
-
0035040640
-
Blue light-induced apoptosis of A2Econtaining RPE: Involvement of caspase-3 and protection by Bcl-2
-
Sparrow JR, Cai B. Blue light-induced apoptosis of A2Econtaining RPE: involvement of caspase-3 and protection by Bcl-2. Invest Ophthalmol Vis Sci. 2001;42:1356-1362.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 1356-1362
-
-
Sparrow, J.R.1
Cai, B.2
-
37
-
-
0034086115
-
The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells
-
Sparrow JR, Nakanishi K, Parish CA. The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Invest Ophthalmol Vis Sci. 2000; 41:1981-1989.
-
(2000)
Invest Ophthalmol Vis Sci.
, vol.41
, pp. 1981-1989
-
-
Sparrow, J.R.1
Nakanishi, K.2
Parish, C.A.3
-
38
-
-
0037705336
-
A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation
-
Sparrow JR, Vollmer-Snarr HR, Zhou J, et al. A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation. J Biol Chem. 2003;278:18207-18213.
-
(2003)
J Biol Chem.
, vol.278
, pp. 18207-18213
-
-
Sparrow, J.R.1
Vollmer-Snarr, H.R.2
Zhou, J.3
-
39
-
-
4143075923
-
The Rpe65 Leu450Met variant is associated with reduced levels of the RPE lipofuscin fluorophores A2E and iso-A2E
-
Kim SR, Fishkin N, Kong J, Nakanishi K, Allikmets R, Sparrow JR. The Rpe65 Leu450Met variant is associated with reduced levels of the RPE lipofuscin fluorophores A2E and iso-A2E. Proc Natl Acad Sci U S A. 2004;101:11668-11672.
-
(2004)
Proc Natl Acad Sci U S A.
, vol.101
, pp. 11668-11672
-
-
Kim, S.R.1
Fishkin, N.2
Kong, J.3
Nakanishi, K.4
Allikmets, R.5
Sparrow, J.R.6
-
40
-
-
79851491559
-
Photoreceptor cell degeneration in Abcr_/_ mice
-
Wu L, Nagasaki T, Sparrow JR. Photoreceptor cell degeneration in Abcr_/_ mice. Adv Exp Med Biol. 2010;664:533-539.
-
(2010)
Adv Exp Med Biol.
, vol.664
, pp. 533-539
-
-
Wu, L.1
Nagasaki, T.2
Sparrow, J.R.3
-
41
-
-
31644442048
-
Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin
-
Kim SR, Nakanishi K, Itagaki Y, Sparrow JR. Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin. Exp Eye Res. 2006;82: 828-839.
-
(2006)
Exp Eye Res.
, vol.82
, pp. 828-839
-
-
Kim, S.R.1
Nakanishi, K.2
Itagaki, Y.3
Sparrow, J.R.4
-
42
-
-
18844379122
-
Isolation and characterization of a retinal pigment epithelial cell fluorophore: An all-trans-retinal dimer conjugate
-
Fishkin N, Sparrow JR, Allikmets R, Nakanishi K. Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate. Proc Natl Acad Sci U S A. 2005;102:7091-7096.
-
(2005)
Proc Natl Acad Sci U S A.
, vol.102
, pp. 7091-7096
-
-
Fishkin, N.1
Sparrow, J.R.2
Allikmets, R.3
Nakanishi, K.4
-
43
-
-
0035146364
-
Rhodopsin-mediated blue-light damage to the rat retina: Effect of photoreversal of bleaching
-
Grimm C, Wenzel A, Williams TP, Rol PO, Hafezi F, Reme CE. Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching. Invest Ophthalmol Vis Sci. 2001;42:497-505.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 497-505
-
-
Grimm, C.1
Wenzel, A.2
Williams, T.P.3
Rol, P.O.4
Hafezi, F.5
Reme, C.E.6
-
44
-
-
0033394514
-
Light-induced retinal damage in mice carrying a mutated SOD I gene
-
Mittag TW, Bayer AU, LaVail MM. Light-induced retinal damage in mice carrying a mutated SOD I gene. Exp Eye Res. 1999;69: 677-683.
-
(1999)
Exp Eye Res.
, vol.69
, pp. 677-683
-
-
Mittag, T.W.1
Bayer, A.U.2
LaVail, M.M.3
-
45
-
-
32944470020
-
Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina
-
Tanito M, Elliot MH, Kotake Y, Anderson RE. Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina. Invest Ophthalmol Vis Sci. 2005;46: 3859-3868.
-
(2005)
Invest Ophthalmol Vis Sci.
, vol.46
, pp. 3859-3868
-
-
Tanito, M.1
Elliot, M.H.2
Kotake, Y.3
Anderson, R.E.4
-
46
-
-
55549115364
-
Retinopathy in mice induced by disrupted all-trans-retinal clearance
-
Maeda A, Maeda T, Golczak M, Palczewski K. Retinopathy in mice induced by disrupted all-trans-retinal clearance. J Biol Chem. 2008;283:26684-26693.
-
(2008)
J Biol Chem.
, vol.283
, pp. 26684-26693
-
-
Maeda, A.1
Maeda, T.2
Golczak, M.3
Palczewski, K.4
-
47
-
-
84876483149
-
Quantitative fundus autofluorescence in mice: Correlation with HPLC quantitation of RPE lipofuscin and measurement of retina outer nuclear layer thickness
-
Sparrow JR, Blonska A, Flynn E, et al. Quantitative fundus autofluorescence in mice: correlation with HPLC quantitation of RPE lipofuscin and measurement of retina outer nuclear layer thickness. Invest Ophthalmol Vis Sci. 2013;54:2812-2820.
-
(2013)
Invest Ophthalmol Vis Sci.
, vol.54
, pp. 2812-2820
-
-
Sparrow, J.R.1
Blonska, A.2
Flynn, E.3
-
48
-
-
53149096200
-
Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation
-
Radu RA, Yuan Q, Hu J, et al. Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation. Invest Ophthalmol Vis Sci. 2008;49:3821-3829.
-
(2008)
Invest Ophthalmol Vis Sci.
, vol.49
, pp. 3821-3829
-
-
Radu, R.A.1
Yuan, Q.2
Hu, J.3
-
49
-
-
20844450821
-
Retinal degeneration 12 (rd12): A new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA)
-
Pang JJ, Chang B, Hawes NL, et al. Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA). Mol Vis. 2005;11:152-162.
-
(2005)
Mol Vis.
, vol.11
, pp. 152-162
-
-
Pang, J.J.1
Chang, B.2
Hawes, N.L.3
-
50
-
-
0034754212
-
Effect of Rpe65 knockout on accumulation of lipofuscin fluorophores in the retinal pigment epithelium
-
Katz ML, Redmond TM. Effect of Rpe65 knockout on accumulation of lipofuscin fluorophores in the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2001;42: 3023-3030.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 3023-3030
-
-
Katz, M.L.1
Redmond, T.M.2
-
51
-
-
70349247885
-
Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/-mice
-
Maeda T, Maeda A, Casadesus G, Palczewski K, Margaron P. Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/-mice. Invest Ophthalmol Vis Sci. 2009;50:4368-4378.
-
(2009)
Invest Ophthalmol Vis Sci.
, vol.50
, pp. 4368-4378
-
-
Maeda, T.1
Maeda, A.2
Casadesus, G.3
Palczewski, K.4
Margaron, P.5
-
52
-
-
79958200565
-
Spatial localization of A2E in the retinal pigment epithelium
-
Grey AC, Crouch RK, Koutalos Y, Schey KL, Ablonczy Z. Spatial localization of A2E in the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2011;52:3926-3933.
-
(2011)
Invest Ophthalmol Vis Sci.
, vol.52
, pp. 3926-3933
-
-
Grey, A.C.1
Crouch, R.K.2
Koutalos, Y.3
Schey, K.L.4
Ablonczy, Z.5
-
53
-
-
47249128518
-
Rpe65-/-and Lrat-/-mice: Comparable models of Leber congenital amaurosis
-
Fan J, Rohrer B, Frederick JM, Baehr W, Crouch RK. Rpe65-/-and Lrat-/-mice: comparable models of Leber congenital amaurosis. Invest Ophthalmol Vis Sci. 2008;49:2384-2389.
-
(2008)
Invest Ophthalmol Vis Sci.
, vol.49
, pp. 2384-2389
-
-
Fan, J.1
Rohrer, B.2
Frederick, J.M.3
Baehr, W.4
Crouch, R.K.5
-
54
-
-
0019190592
-
Possible mechanisms of photoreceptor damage by light in mammalian eyes
-
Noell WK. Possible mechanisms of photoreceptor damage by light in mammalian eyes. Vis Res. 1980;20:1163-1171.
-
(1980)
Vis Res.
, vol.20
, pp. 1163-1171
-
-
Noell, W.K.1
-
55
-
-
0003155537
-
-
New York, NY: Oxford University Press
-
Reme CE, Hafezi F, Marti A, Munz K, Reinboth JJ. Light Damage to Retina and Retinal Pigment Epithelium. New York, NY: Oxford University Press; 1998;68-85.
-
(1998)
Light Damage to Retina and Retinal Pigment Epithelium.
, pp. 68-85
-
-
Reme, C.E.1
Hafezi, F.2
Marti, A.3
Munz, K.4
Reinboth, J.J.5
-
56
-
-
0028329957
-
Retinal light damage:Practical and theoretical considerations
-
Organisciak DT, Winkler BS. Retinal light damage:practical and theoretical considerations. Prog Retin Eye Res. 1994;13:1-29.
-
(1994)
Prog Retin Eye Res.
, vol.13
, pp. 1-29
-
-
Organisciak, D.T.1
Winkler, B.S.2
-
58
-
-
0025425556
-
Hemoprotein(s) mediate blue light damage in the retinal pigment epithelium
-
Pautler EL, Morita M, Beezley D. Hemoprotein(s) mediate blue light damage in the retinal pigment epithelium. Photochem Photobiol. 1990;51:599-605.
-
(1990)
Photochem Photobiol.
, vol.51
, pp. 599-605
-
-
Pautler, E.L.1
Morita, M.2
Beezley, D.3
-
59
-
-
0023683988
-
Morphology and time-course of defined photochemical lesions in the rabbit retina
-
Hoppeler T, Hendrickson P, Dietrich C, Reme CE. Morphology and time-course of defined photochemical lesions in the rabbit retina. Curr Eye Res. 1988;7:849-860.
-
(1988)
Curr Eye Res.
, vol.7
, pp. 849-860
-
-
Hoppeler, T.1
Hendrickson, P.2
Dietrich, C.3
Reme, C.E.4
-
60
-
-
74249113511
-
Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina
-
Maeda A, Golczak M, Maeda T, Palczewski K. Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina. Invest Ophthalmol Vis Sci. 2009;50:5435-5443.
-
(2009)
Invest Ophthalmol Vis Sci.
, vol.50
, pp. 5435-5443
-
-
Maeda, A.1
Golczak, M.2
Maeda, T.3
Palczewski, K.4
-
61
-
-
0021331799
-
Basic mechanisms underlying the production of photochemical lesions in the mammalian retina
-
Ham WT, Mueller HA, Ruffolo JJ, et al. Basic mechanisms underlying the production of photochemical lesions in the mammalian retina. Curr Eye Res. 1984;3:165-174.
-
(1984)
Curr Eye Res.
, vol.3
, pp. 165-174
-
-
Ham, W.T.1
Mueller, H.A.2
Ruffolo, J.J.3
-
62
-
-
0002095714
-
The involvement of the retinal pigment epithelium
-
In: Waxler M, Hitchins VM, eds. Boca Raton, FL: CRC Press, Inc
-
Ham WTJ, Allen RG, Feeney-Burns L, et al. The involvement of the retinal pigment epithelium. In: Waxler M, Hitchins VM, eds. CRC Optical Radiation and Visual Health. Boca Raton, FL: CRC Press, Inc; 1986;43-67.
-
(1986)
CRC Optical Radiation and Visual Health.
, pp. 43-67
-
-
Ham, W.T.J.1
Allen, R.G.2
Feeney-Burns, L.3
-
63
-
-
0014318905
-
The retinal pigment epithelium, IV: The damaging effects of radiant energy
-
Friedman E, Kuwabara T. The retinal pigment epithelium, IV: the damaging effects of radiant energy. Arch Ophthalmol. 1968;80:265-279.
-
(1968)
Arch Ophthalmol.
, vol.80
, pp. 265-279
-
-
Friedman, E.1
Kuwabara, T.2
-
64
-
-
0033190649
-
The effects of two stereoisomers of N-acetylcysteine on photochemical damage by UVA and blue light in rat retina
-
Busch EM, Gorgels TGMF, Roberts JE, van Norren D. The effects of two stereoisomers of N-acetylcysteine on photochemical damage by UVA and blue light in rat retina. Photochem Photobiol. 1999;70:353-358.
-
(1999)
Photochem Photobiol.
, vol.70
, pp. 353-358
-
-
Busch, E.M.1
Gorgels, T.G.M.F.2
Roberts, J.E.3
van Norren, D.4
-
65
-
-
0018188298
-
Histologic analysis of photochemical lesions produced in rhesus retina by short-wavelength light
-
Ham WT, Ruffolo JJ, Mueller HA, Clarke AM, Moon ME. Histologic analysis of photochemical lesions produced in rhesus retina by short-wavelength light. Invest Ophthalmol Vis Sci. 1978;17:1029-1035.
-
(1978)
Invest Ophthalmol Vis Sci.
, vol.17
, pp. 1029-1035
-
-
Ham, W.T.1
Ruffolo, J.J.2
Mueller, H.A.3
Clarke, A.M.4
Moon, M.E.5
-
66
-
-
0026343836
-
Light damage in the rat retina: The effect of dietary deprivation of N-3 fatty acids on acute structural alterations
-
Bush RA, Remé CE, Malnoë A. Light damage in the rat retina: the effect of dietary deprivation of N-3 fatty acids on acute structural alterations. Exp Eye Res. 1991;53:741-752.
-
(1991)
Exp Eye Res.
, vol.53
, pp. 741-752
-
-
Bush, R.A.1
Remé, C.E.2
Malnoë, A.3
-
67
-
-
33750493321
-
Protective effects of soft acrylic yellow filter against blue light-induced retinal damage in rats
-
Tanito M, Kaidzu S, Anderson RE. Protective effects of soft acrylic yellow filter against blue light-induced retinal damage in rats. Exp Eye Res. 2006;83:1493-1504.
-
(2006)
Exp Eye Res.
, vol.83
, pp. 1493-1504
-
-
Tanito, M.1
Kaidzu, S.2
Anderson, R.E.3
-
68
-
-
0026603209
-
Protection by dimethylthiourea against retinal light damage in rats
-
Organisciak DT, Darrow RM, Jiang YI, Marak GE, Blanks JC. Protection by dimethylthiourea against retinal light damage in rats. Invest Ophthalmol Vis Sci. 1992;33:1599-1609.
-
(1992)
Invest Ophthalmol Vis Sci.
, vol.33
, pp. 1599-1609
-
-
Organisciak, D.T.1
Darrow, R.M.2
Jiang, Y.I.3
Marak, G.E.4
Blanks, J.C.5
-
69
-
-
13944272215
-
Mechanism of protection from light-induced retinal degeneration by the synthetic antioxidant phenyl-N-tert-butylnitrone
-
Tomita H, Kotake Y, Anderson RE. Mechanism of protection from light-induced retinal degeneration by the synthetic antioxidant phenyl-N-tert-butylnitrone. Invest Ophthalmol Vis Sci. 2005;46:427-434.
-
(2005)
Invest Ophthalmol Vis Sci.
, vol.46
, pp. 427-434
-
-
Tomita, H.1
Kotake, Y.2
Anderson, R.E.3
-
70
-
-
67249123818
-
Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function
-
Haruta M, Bush RA, Kjellstrom S, et al. Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function. Proc Natl Acad Sci U S A. 2009;2009:9397-9402.
-
(2009)
Proc Natl Acad Sci U S A.
, pp. 9397-9402
-
-
Haruta, M.1
Bush, R.A.2
Kjellstrom, S.3
-
72
-
-
37249077520
-
OT-674 suppresses photooxidative processes initiated by an RPE lipofuscin fluorophore
-
Zhou J, Jang YP, Chang S, Sparrow JR. OT-674 suppresses photooxidative processes initiated by an RPE lipofuscin fluorophore. Photochem Photobiol. 2008;84:75-80.
-
(2008)
Photochem Photobiol.
, vol.84
, pp. 75-80
-
-
Zhou, J.1
Jang, Y.P.2
Chang, S.3
Sparrow, J.R.4
-
73
-
-
34248334629
-
Protective effect of TEMPOL derivatives against light-induced retinal damage in rats
-
Tanito M, Li F, Elliot MH, Dittmar M, Anderson RE. Protective effect of TEMPOL derivatives against light-induced retinal damage in rats. Invest Ophthalmol Vis Sci. 2007;48:1900-1905.
-
(2007)
Invest Ophthalmol Vis Sci.
, vol.48
, pp. 1900-1905
-
-
Tanito, M.1
Li, F.2
Elliot, M.H.3
Dittmar, M.4
Anderson, R.E.5
-
74
-
-
77953359470
-
Protection of retinal pigment epithelium by OT-551 and its metabolite TEMPOL-H against light-induced damage in rats
-
Tanito M, Li F, Anderson RE. Protection of retinal pigment epithelium by OT-551 and its metabolite TEMPOL-H against light-induced damage in rats. Exp Eye Res. 2010;91:111-114.
-
(2010)
Exp Eye Res.
, vol.91
, pp. 111-114
-
-
Tanito, M.1
Li, F.2
Anderson, R.E.3
-
75
-
-
15244351557
-
Mechanisms for the induction of HNE-MDA-and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells
-
Zhou J, Cai B, Jang YP, Pachydaki S, Schmidt AM, Sparrow JR. Mechanisms for the induction of HNE-MDA-and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells. Exp Eye Res. 2005;80:567-580.
-
(2005)
Exp Eye Res.
, vol.80
, pp. 567-580
-
-
Zhou, J.1
Cai, B.2
Jang, Y.P.3
Pachydaki, S.4
Schmidt, A.M.5
Sparrow, J.R.6
-
76
-
-
84865606351
-
Toward an understanding of bisretinoid autofluorescence bleaching and recovery
-
Yamamoto K, Zhou J, Hunter JJ, Williams DR, Sparrow JR. Toward an understanding of bisretinoid autofluorescence bleaching and recovery. Invest Ophthalmol Vis Sci. 2012;53: 3536-3544.
-
(2012)
Invest Ophthalmol Vis Sci.
, vol.53
, pp. 3536-3544
-
-
Yamamoto, K.1
Zhou, J.2
Hunter, J.J.3
Williams, D.R.4
Sparrow, J.R.5
-
77
-
-
62649152376
-
In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic
-
Morgan JI, Dubra A, Wolfe R, Merigan WH, Williams DR. In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic. Invest Ophthalmol Vis Sci. 2009;50:1350-1359.
-
(2009)
Invest Ophthalmol Vis Sci.
, vol.50
, pp. 1350-1359
-
-
Morgan, J.I.1
Dubra, A.2
Wolfe, R.3
Merigan, W.H.4
Williams, D.R.5
-
78
-
-
49049097724
-
Light-induced retinal changes observed with high-resolution autofluorescence imaging of the retinal pigment epithelium
-
Morgan JI, Hunter JJ, Masella B, et al. Light-induced retinal changes observed with high-resolution autofluorescence imaging of the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2008;49:3715-3729.
-
(2008)
Invest Ophthalmol Vis Sci.
, vol.49
, pp. 3715-3729
-
-
Morgan, J.I.1
Hunter, J.J.2
Masella, B.3
-
79
-
-
34249677892
-
Reduced-illuminance autofluorescence imaging in ABCA4-associated retinal degenerations
-
Cideciyan AV, Swider M, Aleman TS, Roman MI, Sumaroka A, Schwartz SB. Reduced-illuminance autofluorescence imaging in ABCA4-associated retinal degenerations. J Opt Soc Am A Opt Image Sci Vis. 2007;24:1457-1467.
-
(2007)
J Opt Soc Am A Opt Image Sci Vis.
, vol.24
, pp. 1457-1467
-
-
Cideciyan, A.V.1
Swider, M.2
Aleman, T.S.3
Roman, M.I.4
Sumaroka, A.5
Schwartz, S.B.6
-
80
-
-
0032499711
-
Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man
-
Cideciyan AV, Hood DC, Huang YZ, et al. Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man. Proc Natl Acad Sci U S A. 1998;95:7103-7108.
-
(1998)
Proc Natl Acad Sci U S A.
, vol.95
, pp. 7103-7108
-
-
Cideciyan, A.V.1
Hood, D.C.2
Huang, Y.Z.3
-
81
-
-
0029972409
-
Light-induced acceleration of photoreceptor degeneration in transgenic mice expressing mutant rhodopsin
-
Naash ML, Peachey NS, Li Z-Y, et al. Light-induced acceleration of photoreceptor degeneration in transgenic mice expressing mutant rhodopsin. Invest Ophthalmol Vis Sci. 1996;37:775-782.
-
(1996)
Invest Ophthalmol Vis Sci.
, vol.37
, pp. 775-782
-
-
Naash, M.L.1
Peachey, N.S.2
Li, Z.-Y.3
-
82
-
-
0030808480
-
Expression of a mutant opsin gene increases the susceptibility of the retina to light damage
-
Wang M, Lam TT, Tso MO, Naash MI. Expression of a mutant opsin gene increases the susceptibility of the retina to light damage. Vis Neurosci. 1997;14:55-62.
-
(1997)
Vis Neurosci.
, vol.14
, pp. 55-62
-
-
Wang, M.1
Lam, T.T.2
Tso, M.O.3
Naash, M.I.4
-
83
-
-
17044393430
-
In vivo dynamics of retinal injury and repair in the rhodopsin mutant dog model of human retinitis pigmentosa
-
Cideciyan AV, Jacobson SG, Aleman TS, et al. In vivo dynamics of retinal injury and repair in the rhodopsin mutant dog model of human retinitis pigmentosa. Proc Natl Acad Sci U S A. 2005; 102:5233-5238.
-
(2005)
Proc Natl Acad Sci U S A.
, vol.102
, pp. 5233-5238
-
-
Cideciyan, A.V.1
Jacobson, S.G.2
Aleman, T.S.3
-
84
-
-
0037311463
-
Susceptibility to retinal light damage in transgenic rats with rhodopsin mutations
-
Organisciak DT, Darrow RM, Barsalou L, Kutty RK, Wiggert B. Susceptibility to retinal light damage in transgenic rats with rhodopsin mutations. Invest Ophthalmol Vis Sci. 2003;44: 486-492.
-
(2003)
Invest Ophthalmol Vis Sci.
, vol.44
, pp. 486-492
-
-
Organisciak, D.T.1
Darrow, R.M.2
Barsalou, L.3
Kutty, R.K.4
Wiggert, B.5
-
85
-
-
2342466682
-
Sunlight and the 10-year incidence of age-related maculopathy: The Beaver Dam Eye Study
-
Tomany SC, Cruickshanks KJ, Klein R, Klein BEK, Knudtson MD. Sunlight and the 10-year incidence of age-related maculopathy: The Beaver Dam Eye Study. Arch Ophthalmol. 2004;122:750-757.
-
(2004)
Arch Ophthalmol.
, vol.122
, pp. 750-757
-
-
Tomany, S.C.1
Cruickshanks, K.J.2
Klein, R.3
Klein, B.E.K.4
Knudtson, M.D.5
-
86
-
-
0034800657
-
Risk factors for age-related maculopathy: The Visual Impairment Project
-
McCarty CA, Mukesh BN, Fu CL, Mitchell P, Wang JJ, Taylor HR. Risk factors for age-related maculopathy: the Visual Impairment Project. Arch Ophthalmol. 2001;119:1455-1462.
-
(2001)
Arch Ophthalmol.
, vol.119
, pp. 1455-1462
-
-
McCarty, C.A.1
Mukesh, B.N.2
Fu, C.L.3
Mitchell, P.4
Wang, J.J.5
Taylor, H.R.6
-
88
-
-
0034793414
-
Light exposure and the risk of age-related macular degeneration
-
Delcourt C, Carriere I, Ponton-Sanchez A, Sourrey S, Lacroux A, Papoz L. Light exposure and the risk of age-related macular degeneration. Arch Ophthalmol. 2001;119:1463-1468.
-
(2001)
Arch Ophthalmol.
, vol.119
, pp. 1463-1468
-
-
Delcourt, C.1
Carriere, I.2
Ponton-Sanchez, A.3
Sourrey, S.4
Lacroux, A.5
Papoz, L.6
-
89
-
-
54049125065
-
Sunlight exposure, antioxidants, and age-related macular degeneration
-
Fletcher AE, Bentham GC, Agnew M, et al. Sunlight exposure, antioxidants, and age-related macular degeneration. Arch Ophthalmol. 2008;126:1396-1403.
-
(2008)
Arch Ophthalmol.
, vol.126
, pp. 1396-1403
-
-
Fletcher, A.E.1
Bentham, G.C.2
Agnew, M.3
|