메뉴 건너뛰기




Volumn 68, Issue 4, 2011, Pages 721-733

Alpha-synuclein deficiency leads to increased glyoxalase i expression and glycation stress

Author keywords

Advanced glycation endproducts; Alpha synuclein deficiency; Glucose metabolism; Glyoxalase I; Transcriptome microarray

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALPHA SYNUCLEIN; GLUCOSE; GLYOXAL; LACTOYLGLUTATHIONE LYASE; METHYLGLYOXAL; TRANSCRIPTOME;

EID: 79951581055     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0483-7     Document Type: Article
Times cited : (69)

References (70)
  • 1
    • 0037954360 scopus 로고    scopus 로고
    • Alpha-synuclein aggregation and neurodegenerative diseases
    • 1:CAS:528:DC%2BD3sXjt1Gis70%3D 12719631
    • QL Ma P Chan M Yoshii K Ueda 2003 Alpha-synuclein aggregation and neurodegenerative diseases J Alzheimers Dis 5 139 148 1:CAS:528: DC%2BD3sXjt1Gis70%3D 12719631
    • (2003) J Alzheimers Dis , vol.5 , pp. 139-148
    • Ma, Q.L.1    Chan, P.2    Yoshii, M.3    Ueda, K.4
  • 5
    • 0036392590 scopus 로고    scopus 로고
    • Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages)
    • Braak H, Del Tredici K, Bratzke H, Hamm-Clement J, Sandmann-Keil D, Rub U (2002) Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages). J Neurol 249(Suppl 3): III/1-5
    • (2002) J Neurol , vol.249 , Issue.SUPPL. 3
    • Braak, H.1    Del Tredici, K.2    Bratzke, H.3    Hamm-Clement, J.4    Sandmann-Keil, D.5    Rub, U.6
  • 6
    • 0027185713 scopus 로고
    • Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease
    • P Jenner 1993 Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease Acta Neurol Scand Suppl 146 6 13 1:STN:280:DyaK3szisFelsg%3D%3D 8333254 (Pubitemid 23251601)
    • (1993) Acta Neurologica Scandinavica, Supplement , vol.87 , Issue.146 , pp. 6-13
    • Jenner, P.1
  • 8
    • 24944525045 scopus 로고    scopus 로고
    • Molecular pathogenesis of Parkinson's disease
    • DOI 10.1093/hmg/ddi308
    • S Gandhi NW Wood 2005 Molecular pathogenesis of Parkinson's disease Hum Mol Genet 14 2749 2755 10.1093/hmg/ddi308 (Pubitemid 41300647)
    • (2005) Human Molecular Genetics , vol.14 , Issue.18 , pp. 2749-2755
    • Gandhi, S.1    Wood, N.W.2
  • 9
    • 68649126827 scopus 로고    scopus 로고
    • Imaging neurodegeneration in Parkinson's disease
    • 1:CAS:528:DC%2BD1MXnsFygs7g%3D 18992326
    • N Pavese DJ Brooks 2009 Imaging neurodegeneration in Parkinson's disease Biochim Biophys Acta 1792 722 729 1:CAS:528:DC%2BD1MXnsFygs7g%3D 18992326
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 722-729
    • Pavese, N.1    Brooks, D.J.2
  • 10
    • 0034527763 scopus 로고    scopus 로고
    • Physiology and pathophysiology of α-synuclein cell culture and transgenic animal models based on a Parkinson's disease-associated protein
    • PJ Kahle M Neumann L Ozmen C Haass 2000 Physiology and pathophysiology of alpha-synuclein. Cell culture and transgenic animal models based on a Parkinson's disease-associated protein Ann NY Acad Sci 920 33 41 1:CAS:528:DC%2BD3MXotlWruw%3D%3D 10.1111/j.1749-6632.2000.tb06902.x 11193173 (Pubitemid 32056549)
    • (2000) Annals of the New York Academy of Sciences , vol.920 , pp. 33-41
    • Kahle, P.J.1    Neumann, M.2    Ozmen, L.3    Haass, C.4
  • 13
    • 41949097891 scopus 로고    scopus 로고
    • C. elegans model identifies genetic modifiers of α-synuclein inclusion formation during aging
    • DOI 10.1371/journal.pgen.1000027
    • TJ van Ham KL Thijssen R Breitling RM Hofstra RH Plasterk EA Nollen 2008 C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging PLoS Genet 4 e1000027 10.1371/journal.pgen.1000027 18369446 (Pubitemid 351507866)
    • (2008) PLoS Genetics , vol.4 , Issue.3
    • Van Ham, T.J.1    Thijssen, K.L.2    Breitling, R.3    Hofstra, R.M.W.4    Plasterk, R.H.A.5    Nollen, E.A.A.6
  • 15
    • 68649095418 scopus 로고    scopus 로고
    • Molecular mechanisms of alpha-synuclein neurodegeneration
    • 1:CAS:528:DC%2BD1MXnsFygsrg%3D 18955133
    • EA Waxman BI Giasson 2009 Molecular mechanisms of alpha-synuclein neurodegeneration Biochim Biophys Acta 1792 616 624 1:CAS:528: DC%2BD1MXnsFygsrg%3D 18955133
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 616-624
    • Waxman, E.A.1    Giasson, B.I.2
  • 16
    • 27544507306 scopus 로고    scopus 로고
    • α-Synuclein cooperates with CSPα in preventing neurodegeneration
    • DOI 10.1016/j.cell.2005.09.028, PII S0092867405010226
    • S Chandra G Gallardo R Fernandez-Chacon OM Schluter TC Sudhof 2005 Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration Cell 123 383 396 1:CAS:528:DC%2BD2MXht1altLnN 10.1016/j.cell.2005.09.028 16269331 (Pubitemid 41546670)
    • (2005) Cell , vol.123 , Issue.3 , pp. 383-396
    • Chandra, S.1    Gallardo, G.2    Fernandez-Chacon, R.3    Schluter, O.M.4    Sudhof, T.C.5
  • 17
    • 77952900626 scopus 로고    scopus 로고
    • Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs
    • 1:CAS:528:DC%2BC3cXpslyrt7g%3D 10.1091/mbc.E09-09-0801 20392839
    • N Thayanidhi JR Helm DC Nycz M Bentley Y Liang JC Hay 2010 Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs Mol Biol Cell 21 1850 1863 1:CAS:528:DC%2BC3cXpslyrt7g%3D 10.1091/mbc.E09-09-0801 20392839
    • (2010) Mol Biol Cell , vol.21 , pp. 1850-1863
    • Thayanidhi, N.1    Helm, J.R.2    Nycz, D.C.3    Bentley, M.4    Liang, Y.5    Hay, J.C.6
  • 18
  • 20
    • 34548726221 scopus 로고    scopus 로고
    • Role of α-synuclein in synaptic glutamate release
    • DOI 10.1016/j.nbd.2007.06.016, PII S0969996107001362
    • I Gureviciene K Gurevicius H Tanila 2007 Role of alpha-synuclein in synaptic glutamate release Neurobiol Dis 28 83 89 1:CAS:528:DC%2BD2sXhtVOgur3N 10.1016/j.nbd.2007.06.016 17689254 (Pubitemid 47429976)
    • (2007) Neurobiology of Disease , vol.28 , Issue.1 , pp. 83-89
    • Gureviciene, I.1    Gurevicius, K.2    Tanila, H.3
  • 23
    • 40549093026 scopus 로고    scopus 로고
    • Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein
    • DOI 10.1111/j.1460-9568.2008.06055.x
    • SL Senior N Ninkina R Deacon D Bannerman VL Buchman SJ Cragg R Wade-Martins 2008 Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein Eur J Neurosci 27 947 957 10.1111/j.1460-9568.2008.06055.x 18333965 (Pubitemid 351365167)
    • (2008) European Journal of Neuroscience , vol.27 , Issue.4 , pp. 947-957
    • Senior, S.L.1    Ninkina, N.2    Deacon, R.3    Bannerman, D.4    Buchman, V.L.5    Cragg, S.J.6    Wade-Martins, R.7
  • 25
    • 34347387566 scopus 로고    scopus 로고
    • α-Synuclein involvement in hippocampal synaptic plasticity: Role of NO, cGMP, cGK and CaMKII
    • DOI 10.1111/j.1460-9568.2007.05569.x
    • S Liu M Fa I Ninan F Trinchese W Dauer O Arancio 2007 Alpha-synuclein involvement in hippocampal synaptic plasticity: role of NO, cGMP, cGK and CaMKII Eur J Neurosci 25 3583 3596 10.1111/j.1460-9568.2007.05569.x 17610578 (Pubitemid 47020438)
    • (2007) European Journal of Neuroscience , vol.25 , Issue.12 , pp. 3583-3596
    • Liu, S.1    Fa, M.2    Ninan, I.3    Trinchese, F.4    Dauer, W.5    Arancio, O.6
  • 26
    • 27644578107 scopus 로고    scopus 로고
    • Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking α-synuclein
    • DOI 10.1128/MCB.25.22.10190-10201.2005
    • CE Ellis EJ Murphy DC Mitchell MY Golovko F Scaglia GC Barcelo-Coblijn RL Nussbaum 2005 Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein Mol Cell Biol 25 10190 10201 1:CAS:528:DC%2BD2MXht1altrbJ 10.1128/MCB.25.22.10190-10201.2005 16260631 (Pubitemid 41572763)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.22 , pp. 10190-10201
    • Ellis, C.E.1    Murphy, E.J.2    Mitchell, D.C.3    Golovko, M.Y.4    Scaglia, F.5    Barcelo-Coblijn, G.C.6    Nussbaum, R.L.7
  • 27
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • R Edgar M Domrachev AE Lash 2002 Gene Expression Omnibus: NCBI gene expression and hybridization array data repository Nucleic Acids Res 30 207 210 1:CAS:528:DC%2BD38Xht12kurs%3D 10.1093/nar/30.1.207 11752295 (Pubitemid 34679544)
    • (2002) Nucleic Acids Research , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 29
    • 1342288026 scopus 로고    scopus 로고
    • Affy - Analysis of Affymetrix GeneChip data at the probe level
    • DOI 10.1093/bioinformatics/btg405
    • L Gautier L Cope BM Bolstad RA Irizarry 2004 affy-analysis of Affymetrix GeneChip data at the probe level Bioinformatics 20 307 315 1:CAS:528: DC%2BD2cXht1Kksr4%3D 10.1093/bioinformatics/btg405 14960456 (Pubitemid 38262761)
    • (2004) Bioinformatics , vol.20 , Issue.3 , pp. 307-315
    • Gautier, L.1    Cope, L.2    Bolstad, B.M.3    Irizarry, R.A.4
  • 30
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article 3
    • Smyth GK (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3. (Article3)
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 31
    • 33644872577 scopus 로고    scopus 로고
    • Limma: Linear models for microarray data
    • R.C. Gentleman (eds) et al. Springer Berlin Heidelberg New York. 10.1007/0-387-29362-0-23
    • Smyth GK (2005) Limma: linear models for microarray data. In: Gentleman RC et al (eds) Bioinformatics and computational biology solutions using R and bioconductor. Springer, Berlin Heidelberg New York, pp 397-420
    • (2005) Bioinformatics and Computational Biology Solutions Using R and Bioconductor , pp. 397-420
    • Smyth, G.K.1
  • 32
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 402 408 1:CAS:528:DC%2BD38XhtFelt7s%3D 10.1006/meth.2001.1262 11846609 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 33
    • 0006074326 scopus 로고
    • S-2-Hydroxyacylglutathione-derivates: Enzymatic preparation, purification and characterization
    • Clelland JD, Thornalley PJ (1991) S-2-Hydroxyacylglutathione-derivates: enzymatic preparation, purification and characterisation. J Chem Soc Perkin Trans I, 3009-3015
    • (1991) J Chem Soc Perkin Trans , vol.1 , pp. 3009-3015
    • Clelland, J.D.1    Thornalley, P.J.2
  • 34
    • 9644291555 scopus 로고    scopus 로고
    • Processing of protein glycation, oxidation and nitrosation adducts in the liver and the effect of cirrhosis
    • DOI 10.1016/j.jhep.2004.08.007, PII S0168827804003757
    • N Ahmed PJ Thornalley R Luthen D Haussinger K Sebekova R Schinzel W Voelker A Heidland 2004 Processing of protein glycation, oxidation and nitrosation adducts in the liver and the effect of cirrhosis J Hepatol 41 913 919 1:CAS:528:DC%2BD2cXhtVCgsLzO 10.1016/j.jhep.2004.08.007 15582123 (Pubitemid 39575657)
    • (2004) Journal of Hepatology , vol.41 , Issue.6 , pp. 913-919
    • Ahmed, N.1    Thornalley, P.J.2    Luthen, R.3    Haussinger, D.4    Sebekova, K.5    Schinzel, R.6    Voelker, W.7    Heidland, A.8
  • 35
    • 0037093336 scopus 로고    scopus 로고
    • ε-(1-carboxyethyl)lysine-modified albumin
    • N Ahmed OK Argirov HS Minhas CA Cordeiro PJ Thornalley 2002 Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysine- and Nepsilon-(1-carboxyethyl) lysine-modified albumin Biochem J 364 1 14 1:CAS:528:DC%2BD38XktFWiuro%3D 11988070 (Pubitemid 34538940)
    • (2002) Biochemical Journal , vol.364 , Issue.1 , pp. 1-14
    • Ahmed, N.1    Argirov, O.K.2    Minhas, H.S.3    Cordeiro, C.A.A.4    Thornalley, P.J.5
  • 36
    • 0347419281 scopus 로고    scopus 로고
    • Glyoxalase I - Structure, function and a critical role in the enzymatic defence against glycation
    • PJ Thornalley 2003 Glyoxalase I-structure, function and a critical role in the enzymatic defence against glycation Biochem Soc Trans 31 1343 1348 1:CAS:528:DC%2BD3sXps12jtrw%3D 10.1042/BST0311343 14641060 (Pubitemid 38030973)
    • (2003) Biochemical Society Transactions , vol.31 , Issue.6 , pp. 1343-1348
    • Thornalley, P.J.1
  • 37
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • 1:STN:280:DyaK2Mzgt1GhtQ%3D%3D 10.1089/neu.1995.12.1 7783230
    • DM Basso MS Beattie JC Bresnahan 1995 A sensitive and reliable locomotor rating scale for open field testing in rats J Neurotrauma 12 1 21 1:STN:280:DyaK2Mzgt1GhtQ%3D%3D 10.1089/neu.1995.12.1 7783230
    • (1995) J Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 38
    • 77249161634 scopus 로고    scopus 로고
    • Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization
    • 1:CAS:528:DC%2BC3cXis1ensbs%3D 10.1016/j.neuroscience.2009.12.054 20056137
    • A Kurz M Wohr M Walter M Bonin G Auburger S Gispert RK Schwarting 2010 Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization Neuroscience 166 785 795 1:CAS:528:DC%2BC3cXis1ensbs%3D 10.1016/j.neuroscience.2009.12.054 20056137
    • (2010) Neuroscience , vol.166 , pp. 785-795
    • Kurz, A.1    Wohr, M.2    Walter, M.3    Bonin, M.4    Auburger, G.5    Gispert, S.6    Schwarting, R.K.7
  • 40
    • 0029610872 scopus 로고
    • Molecular characterization of glyoxalase-I from a higher plant; Upregulation by stress
    • J Espartero I Sanchez-Aguayo JM Pardo 1995 Molecular characterization of glyoxalase-I from a higher plant; upregulation by stress Plant Mol Biol 29 1223 1233 1:CAS:528:DyaK28Xht1eit7c%3D 10.1007/BF00020464 8616220 (Pubitemid 2618683)
    • (1995) Plant Molecular Biology , vol.29 , Issue.6 , pp. 1223-1233
    • Espartero, J.1    Sanchez-Aguayo, I.2    Pardo, J.M.3
  • 41
    • 77951896005 scopus 로고    scopus 로고
    • Methylglyoxal-mediated anxiolysis involves increased protein modification and elevated expression of glyoxalase 1 in the brain
    • 1:CAS:528:DC%2BC3cXnt1Gnsbw%3D 20345757
    • B Hambsch BG Chen J Brenndorfer M Meyer C Avrabos G Maccarrone RH Liu M Eder CW Turck R Landgraf 2010 Methylglyoxal-mediated anxiolysis involves increased protein modification and elevated expression of glyoxalase 1 in the brain J Neurochem 113 1240 1251 1:CAS:528:DC%2BC3cXnt1Gnsbw%3D 20345757
    • (2010) J Neurochem , vol.113 , pp. 1240-1251
    • Hambsch, B.1    Chen, B.G.2    Brenndorfer, J.3    Meyer, M.4    Avrabos, C.5    MacCarrone, G.6    Liu, R.H.7    Eder, M.8    Turck, C.W.9    Landgraf, R.10
  • 42
    • 77957186229 scopus 로고
    • Subchronic oral toxicity of glyoxal via drinking water in rats
    • 1:CAS:528:DyaK3MXisValsr8%3D 10.1016/0272-0590(91)90162-W 1884914
    • H Ueno T Segawa T Hasegawa K Nakamuro H Maeda Y Hiramatsu S Okada Y Sayato 1991 Subchronic oral toxicity of glyoxal via drinking water in rats Fundam Appl Toxicol 16 763 772 1:CAS:528:DyaK3MXisValsr8%3D 10.1016/0272- 0590(91)90162-W 1884914
    • (1991) Fundam Appl Toxicol , vol.16 , pp. 763-772
    • Ueno, H.1    Segawa, T.2    Hasegawa, T.3    Nakamuro, K.4    Maeda, H.5    Hiramatsu, Y.6    Okada, S.7    Sayato, Y.8
  • 43
    • 43449094351 scopus 로고    scopus 로고
    • Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems - Role in ageing and disease
    • PJ Thornalley 2008 Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems-role in ageing and disease Drug Metabol Drug Interact 23 125 150 1:CAS:528:DC%2BD1cXmtFamsL4%3D 18533367 (Pubitemid 351669568)
    • (2008) Drug Metabolism and Drug Interactions , vol.23 , Issue.1-2 , pp. 125-150
    • Thornalley, P.J.1
  • 46
    • 8744307268 scopus 로고    scopus 로고
    • Tissue distribution and evolution of fructosamine 3-kinase and fructosamine 3-kinase-related protein
    • DOI 10.1074/jbc.M407678200
    • J Delplanque G Delpierre FR Opperdoes E Van Schaftingen 2004 Tissue distribution and evolution of fructosamine 3-kinase and fructosamine 3-kinase-related protein J Biol Chem 279 46606 46613 1:CAS:528: DC%2BD2cXptFaqtb8%3D 10.1074/jbc.M407678200 15331600 (Pubitemid 39518305)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.45 , pp. 46606-46613
    • Delplanque, J.1    Delpierre, G.2    Opperdoes, F.R.3    Van Schaftingen, E.4
  • 51
    • 2642553802 scopus 로고    scopus 로고
    • Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ-synuclein, α-synuclein and double α/γ-synuclein null mutant mice
    • DOI 10.1111/j.1471-4159.2004.02378.x
    • DC Robertson O Schmidt N Ninkina PA Jones J Sharkey VL Buchman 2004 Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice J Neurochem 89 1126 1136 1:CAS:528:DC%2BD2cXkvFOktb0%3D 10.1111/j.1471-4159.2004.02378.x 15147505 (Pubitemid 38715830)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.5 , pp. 1126-1136
    • Robertson, D.C.1    Schmidt, O.2    Ninkina, N.3    Jones, P.A.4    Sharkey, J.5    Buchman, V.L.6
  • 52
    • 0038404962 scopus 로고    scopus 로고
    • Role of α-synuclein in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced Parkinsonism in mice
    • DOI 10.1016/S0306-4522(03)00036-8
    • OM Schluter F Fornai MG Alessandri S Takamori M Geppert R Jahn TC Sudhof 2003 Role of alpha-synuclein in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine- induced parkinsonism in mice Neuroscience 118 985 1002 1:CAS:528: DC%2BD3sXjsVejsrk%3D 10.1016/S0306-4522(03)00036-8 12732244 (Pubitemid 36561187)
    • (2003) Neuroscience , vol.118 , Issue.4 , pp. 985-1002
    • Schluter, O.M.1    Fornai, F.2    Alessandri, M.G.3    Takamori, S.4    Geppert, M.5    Jahn, R.6    Sudhof, T.C.7
  • 53
    • 34249113517 scopus 로고    scopus 로고
    • Lipid nitration and formation of lipid-protein adducts: Biological insights
    • DOI 10.1007/s00726-006-0426-7, Special Issue: Focus on Amino Acid and Protein Modification by Oxygen and Nitrogen Species
    • A Trostchansky H Rubbo 2007 Lipid nitration and formation of lipid-protein adducts: biological insights Amino Acids 32 517 522 1:CAS:528:DC%2BD2sXlsVGnsLs%3D 10.1007/s00726-006-0426-7 17058116 (Pubitemid 46790932)
    • (2007) Amino Acids , vol.32 , Issue.4 , pp. 517-522
    • Trostchansky, A.1    Rubbo, H.2
  • 54
    • 59649096230 scopus 로고    scopus 로고
    • Microarray expression analysis of human dopaminergic neuroblastoma cells after RNA interference of SNCA-a key player in the pathogenesis of Parkinson's disease
    • 10.1016/j.brainres.2008.12.020 19135032
    • K Habig M Walter H Stappert O Riess M Bonin 2009 Microarray expression analysis of human dopaminergic neuroblastoma cells after RNA interference of SNCA-a key player in the pathogenesis of Parkinson's disease Brain Res 1256 19 33 10.1016/j.brainres.2008.12.020 19135032
    • (2009) Brain Res , vol.1256 , pp. 19-33
    • Habig, K.1    Walter, M.2    Stappert, H.3    Riess, O.4    Bonin, M.5
  • 58
    • 0343554069 scopus 로고    scopus 로고
    • Advanced glycation endproducts in ageing and Alzheimer's disease
    • DOI 10.1016/S0165-0173(96)00016-1, PII S0165017396000161
    • G Munch J Thome P Foley R Schinzel P Riederer 1997 Advanced glycation endproducts in ageing and Alzheimer's disease Brain Res Brain Res Rev 23 134 143 1:STN:280:DyaK2s3hslKhug%3D%3D 10.1016/S0165-0173(96)00016-1 9063589 (Pubitemid 27090752)
    • (1997) Brain Research Reviews , vol.23 , Issue.1-2 , pp. 134-143
    • Munch, G.1    Thome, J.2    Foley, P.3    Schinzel, R.4    Riederer, P.5
  • 59
    • 34247860742 scopus 로고    scopus 로고
    • Lack of α-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease
    • DOI 10.1186/1750-1326-2-6
    • V Kallhoff E Peethumnongsin H Zheng 2007 Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease Mol Neurodegener 2 6 10.1186/1750-1326-2-6 17367539 (Pubitemid 46698828)
    • (2007) Molecular Neurodegeneration , vol.2 , Issue.1 , pp. 6
    • Kallhoff, V.1    Peethumnongsin, E.2    Zheng, H.3
  • 60
    • 77956989586 scopus 로고    scopus 로고
    • Advanced glycation end products as biomarkers and gerontotoxins-a basis to explore methylglyoxal-lowering agents for Alzheimer's disease?
    • [Epub ahead of print]
    • Krautwald M, Munch G (2010) Advanced glycation end products as biomarkers and gerontotoxins-a basis to explore methylglyoxal-lowering agents for Alzheimer's disease? Exp Gerontol [Epub ahead of print]
    • (2010) Exp Gerontol
    • Krautwald, M.1    Munch, G.2
  • 61
    • 35348866703 scopus 로고    scopus 로고
    • O-GlcNAc modification in diabetes and Alzheimer's disease
    • DOI 10.1039/b704905f
    • WB Dias GW Hart 2007 O-GlcNAc modification in diabetes and Alzheimer's disease Mol Biosyst 3 766 772 1:CAS:528:DC%2BD2sXhtFKlsLbI 10.1039/b704905f 17940659 (Pubitemid 47587186)
    • (2007) Molecular BioSystems , vol.3 , Issue.11 , pp. 766-772
    • Dias, W.B.1    Hart, G.W.2
  • 62
    • 69749096429 scopus 로고    scopus 로고
    • Crosstalk between calcium, amyloid beta and the receptor for advanced glycation endproducts in Alzheimer's disease
    • 1:CAS:528:DC%2BD1MXhtFCkurrL 19774788
    • E Leclerc E Sturchler SW Vetter CW Heizmann 2009 Crosstalk between calcium, amyloid beta and the receptor for advanced glycation endproducts in Alzheimer's disease Rev Neurosci 20 95 110 1:CAS:528:DC%2BD1MXhtFCkurrL 19774788
    • (2009) Rev Neurosci , vol.20 , pp. 95-110
    • Leclerc, E.1    Sturchler, E.2    Vetter, S.W.3    Heizmann, C.W.4
  • 63
    • 38449100485 scopus 로고    scopus 로고
    • A receptor γ2 subunit mutations linked to human epileptic syndromes differentially affect phasic and tonic inhibition
    • DOI 10.1523/JNEUROSCI.2618-07.2007
    • E Eugene C Depienne S Baulac M Baulac JM Fritschy E Le Guern R Miles JC Poncer 2007 GABA(A) receptor gamma 2 subunit mutations linked to human epileptic syndromes differentially affect phasic and tonic inhibition J Neurosci 27 14108 14116 1:CAS:528:DC%2BD1cXisVGgtA%3D%3D 10.1523/JNEUROSCI.2618-07.2007 18094250 (Pubitemid 351377877)
    • (2007) Journal of Neuroscience , vol.27 , Issue.51 , pp. 14108-14116
    • Eugene, E.1    Depienne, C.2    Baulac, S.3    Baulac, M.4    Fritschy, J.M.5    Le Guern, E.6    Miles, R.7    Poncer, J.C.8
  • 64
    • 0348136791 scopus 로고    scopus 로고
    • Protecting the genome: Defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy
    • PJ Thornalley 2003 Protecting the genome: defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy Biochem Soc Trans 31 1372 1377 1:CAS:528:DC%2BD3sXps12jtrc%3D 10.1042/BST0311372 14641066 (Pubitemid 38030979)
    • (2003) Biochemical Society Transactions , vol.31 , Issue.6 , pp. 1372-1377
    • Thornalley, P.J.1
  • 65
    • 23944469448 scopus 로고    scopus 로고
    • The Isy1p component of the NineTeen Complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing
    • DOI 10.1101/gad.1336305
    • T Villa C Guthrie 2005 The Isy1p component of the NineTeen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing Genes Dev 19 1894 1904 1:CAS:528:DC%2BD2MXpsFCqsrk%3D 10.1101/gad.1336305 16103217 (Pubitemid 41186990)
    • (2005) Genes and Development , vol.19 , Issue.16 , pp. 1894-1904
    • Villa, T.1    Guthrie, C.2
  • 66
    • 9644267105 scopus 로고    scopus 로고
    • FIGC, a novel FGF-induced ubiquitin-protein ligase in gastric cancers
    • DOI 10.1016/j.febslet.2004.10.071, PII S0014579304013079
    • JH Jang 2004 FIGC, a novel FGF-induced ubiquitin-protein ligase in gastric cancers FEBS Lett 578 21 25 1:CAS:528:DC%2BD2cXhtVClt7jF 10.1016/j.febslet.2004.10.071 15581609 (Pubitemid 39576093)
    • (2004) FEBS Letters , vol.578 , Issue.1-2 , pp. 21-25
    • Jang, J.-H.1
  • 67
    • 0028940972 scopus 로고
    • DNA polymerases required for repair of UV-induced damage in Saccharomyces cerevisiae
    • 1:CAS:528:DyaK2MXksFWjtLo%3D 7891712
    • ME Budd JL Campbell 1995 DNA polymerases required for repair of UV-induced damage in Saccharomyces cerevisiae Mol Cell Biol 15 2173 2179 1:CAS:528:DyaK2MXksFWjtLo%3D 7891712
    • (1995) Mol Cell Biol , vol.15 , pp. 2173-2179
    • Budd, M.E.1    Campbell, J.L.2
  • 68
    • 0025515491 scopus 로고
    • DNA polymerase epsilon: The latest member in the family of mammalian DNA polymerases
    • JE Syvaoja 1990 DNA polymerase epsilon: the latest member in the family of mammalian DNA polymerases Bioessays 12 533 536 1:CAS:528:DyaK3MXit1CjtL8%3D 10.1002/bies.950121106 2085320 (Pubitemid 120034337)
    • (1990) BioEssays , vol.12 , Issue.11 , pp. 533-536
    • Syvaoja, J.E.1
  • 69
    • 0033636996 scopus 로고    scopus 로고
    • The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing
    • 1:CAS:528:DC%2BD3cXosV2mtro%3D 10.1016/S1097-2765(00)00107-6 11106748
    • P Forch O Puig N Kedersha C Martinez S Granneman B Seraphin P Anderson J Valcarcel 2000 The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing Mol Cell 6 1089 1098 1:CAS:528: DC%2BD3cXosV2mtro%3D 10.1016/S1097-2765(00)00107-6 11106748
    • (2000) Mol Cell , vol.6 , pp. 1089-1098
    • Forch, P.1    Puig, O.2    Kedersha, N.3    Martinez, C.4    Granneman, S.5    Seraphin, B.6    Anderson, P.7    Valcarcel, J.8
  • 70
    • 0026091180 scopus 로고
    • A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells
    • Q Tian M Streuli H Saito SF Schlossman P Anderson 1991 A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells Cell 67 629 639 1:CAS:528:DyaK3sXitVGntw%3D%3D 10.1016/0092-8674(91)90536-8 1934064 (Pubitemid 121001476)
    • (1991) Cell , vol.67 , Issue.3 , pp. 629-639
    • Tian, Q.1    Streuli, M.2    Saito, H.3    Schlossman, S.F.4    Anderson, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.