-
1
-
-
84896922844
-
Glyoxalase centennial conference: Introduction, history of research on the glyoxalase system and future prospects
-
N. Rabbani, and P.J. Thornalley Glyoxalase centennial conference: introduction, history of research on the glyoxalase system and future prospects Biochem. Soc. Trans. 42 2014 413 418
-
(2014)
Biochem. Soc. Trans.
, vol.42
, pp. 413-418
-
-
Rabbani, N.1
Thornalley, P.J.2
-
2
-
-
84904988908
-
Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples
-
N. Rabbani, and P.J. Thornalley Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples Nat. Protoc. 9 2014 1969 1979
-
(2014)
Nat. Protoc.
, vol.9
, pp. 1969-1979
-
-
Rabbani, N.1
Thornalley, P.J.2
-
3
-
-
0345282976
-
Methylglyoxal-derived hydroimidazolone advanced glycation endproducts of human lens proteins
-
N. Ahmed, P.J. Thornalley, J. Dawczynski, S. Franke, J. Strobel, G. Stein, and G.M. Haik Jr. Methylglyoxal-derived hydroimidazolone advanced glycation endproducts of human lens proteins Invest. Ophthalmol. Vis. Sci. 44 2003 5287 5292
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 5287-5292
-
-
Ahmed, N.1
Thornalley, P.J.2
Dawczynski, J.3
Franke, S.4
Strobel, J.5
Stein, G.6
Haik, Jr.G.M.7
-
4
-
-
0028292698
-
The glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications
-
A.C. McLellan, P.J. Thornalley, J. Benn, and P.H. Sonksen The glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications Clin. Sci. 87 1994 21 29
-
(1994)
Clin. Sci.
, vol.87
, pp. 21-29
-
-
McLellan, A.C.1
Thornalley, P.J.2
Benn, J.3
Sonksen, P.H.4
-
5
-
-
84888699320
-
-
John Wiley & Sons, Inc
-
N. Rabbani, and P.J. Thornalley Dicarbonyls (Glyoxal, Methylglyoxal, and 3-Deoxyglucosone), Uremic Toxins 2012 John Wiley & Sons, Inc 177 192
-
(2012)
Dicarbonyls (Glyoxal, Methylglyoxal, and 3-Deoxyglucosone), Uremic Toxins
, pp. 177-192
-
-
Rabbani, N.1
Thornalley, P.J.2
-
6
-
-
84896930134
-
Assay of methylglyoxal and glyoxal and control of peroxidase interference
-
P.J. Thornalley, and N. Rabbani Assay of methylglyoxal and glyoxal and control of peroxidase interference Biochem. Soc. Trans. 42 2014 504 510
-
(2014)
Biochem. Soc. Trans.
, vol.42
, pp. 504-510
-
-
Thornalley, P.J.1
Rabbani, N.2
-
7
-
-
84887120701
-
Metabolic transit of dietary methylglyoxal
-
J. Degen, M. Vogel, D. Richter, M. Hellwig, and T. Henle Metabolic transit of dietary methylglyoxal J. Agric. Food Chem. 61 2013 10253 10260
-
(2013)
J. Agric. Food Chem.
, vol.61
, pp. 10253-10260
-
-
Degen, J.1
Vogel, M.2
Richter, D.3
Hellwig, M.4
Henle, T.5
-
8
-
-
84896522444
-
Dietary influence on urinary excretion of 3-deoxyglucosone and its metabolite 3-deoxyfructose
-
J. Degen, H. Beyer, B. Heymann, M. Hellwig, and T. Henle Dietary influence on urinary excretion of 3-deoxyglucosone and its metabolite 3-deoxyfructose J. Agric. Food Chem. 62 2014 2449 2456
-
(2014)
J. Agric. Food Chem.
, vol.62
, pp. 2449-2456
-
-
Degen, J.1
Beyer, H.2
Heymann, B.3
Hellwig, M.4
Henle, T.5
-
9
-
-
84896939460
-
Activity, regulation, copy number and function in the glyoxalase system
-
N. Rabbani, M. Xue, and P.J. Thornalley Activity, regulation, copy number and function in the glyoxalase system Biochem. Soc. Trans. 42 2014 419 424
-
(2014)
Biochem. Soc. Trans.
, vol.42
, pp. 419-424
-
-
Rabbani, N.1
Xue, M.2
Thornalley, P.J.3
-
10
-
-
84922264295
-
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine and lysine residues
-
G. Richarme, M. Mihoub, J. Dairou, L.-C. Bui, T. Leger, and A. Lamouri Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine and lysine residues J. Biol. Chem. 290 2015 1885 1897
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 1885-1897
-
-
Richarme, G.1
Mihoub, M.2
Dairou, J.3
Bui, L.-C.4
Leger, T.5
Lamouri, A.6
-
11
-
-
0028605299
-
Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with Nα-acetylarginine, Nα-acetylcysteine, Nα-acetyl-lysine, and bovine serum albumin
-
T.W.C. Lo, M.E. Westwood, A.C. McLellan, T. Selwood, and P.J. Thornalley Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with Nα-acetylarginine, Nα-acetylcysteine, Nα-acetyl-lysine, and bovine serum albumin J. Biol. Chem. 269 1994 32299 32305
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32299-32305
-
-
Lo, T.W.C.1
Westwood, M.E.2
McLellan, A.C.3
Selwood, T.4
Thornalley, P.J.5
-
12
-
-
84858323567
-
A global perspective of the genetic basis for carbonyl stress resistance
-
S. Hoon, M. Gebbia, M. Costanzo, R.W. Davis, G. Giaever, and C. Nislow A global perspective of the genetic basis for carbonyl stress resistance G3 (Bethesda Md.) 1 2011
-
(2011)
G3 (Bethesda Md.)
, vol.1
-
-
Hoon, S.1
Gebbia, M.2
Costanzo, M.3
Davis, R.W.4
Giaever, G.5
Nislow, C.6
-
13
-
-
40549129694
-
Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans
-
M. Morcos, X. Du, F. Pfisterer, H. Hutter, A.A.R. Sayed, P. Thornalley, N. Ahmed, J. Baynes, S. Thorpe, G. Kukudov, A. Schlotterer, F. Bozorgmehr, R.A. El Baki, D. Stern, F. Moehrlen, Y. Ibrahim, D. Oikonomou, A. Hamann, C. Becker, M. Zeier, V. Schwenger, N. Miftari, P. Humpert, H.P. Hammes, M. Buechler, A. Bierhaus, M. Brownlee, and P.P. Nawroth Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans Aging Cell. 7 2008 260 269
-
(2008)
Aging Cell.
, vol.7
, pp. 260-269
-
-
Morcos, M.1
Du, X.2
Pfisterer, F.3
Hutter, H.4
Sayed, A.A.R.5
Thornalley, P.6
Ahmed, N.7
Baynes, J.8
Thorpe, S.9
Kukudov, G.10
Schlotterer, A.11
Bozorgmehr, F.12
El Baki, R.A.13
Stern, D.14
Moehrlen, F.15
Ibrahim, Y.16
Oikonomou, D.17
Hamann, A.18
Becker, C.19
Zeier, M.20
Schwenger, V.21
Miftari, N.22
Humpert, P.23
Hammes, H.P.24
Buechler, M.25
Bierhaus, A.26
Brownlee, M.27
Nawroth, P.P.28
more..
-
14
-
-
77449142258
-
Hyperglycemia-induced reactive oxygen species increase expression of RAGE and RAGE ligands
-
D. Yao, and M. Brownlee Hyperglycemia-induced reactive oxygen species increase expression of RAGE and RAGE ligands Diabetes 59 2009 249 255
-
(2009)
Diabetes
, vol.59
, pp. 249-255
-
-
Yao, D.1
Brownlee, M.2
-
15
-
-
33847078455
-
Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-jun N-terminal kinase, caspase-3, and p21-activated kinase 2
-
W.H. Chan, H.J. Wu, and N.H. Shiao Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-jun N-terminal kinase, caspase-3, and p21-activated kinase 2 J. Cell. Biochem. 100 2007 1056 1069
-
(2007)
J. Cell. Biochem.
, vol.100
, pp. 1056-1069
-
-
Chan, W.H.1
Wu, H.J.2
Shiao, N.H.3
-
16
-
-
33747080843
-
Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification
-
D. Dobler, N. Ahmed, L.J. Song, K.E. Eboigbodin, and P.J. Thornalley Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification Diabetes 55 2006 1961 1969
-
(2006)
Diabetes
, vol.55
, pp. 1961-1969
-
-
Dobler, D.1
Ahmed, N.2
Song, L.J.3
Eboigbodin, K.E.4
Thornalley, P.J.5
-
17
-
-
84896944320
-
Dicarbonyl proteome and genome damage in metabolic and vascular disease
-
N. Rabbani, and P.J. Thornalley Dicarbonyl proteome and genome damage in metabolic and vascular disease Biochem. Soc. Trans. 42 2014 425 432
-
(2014)
Biochem. Soc. Trans.
, vol.42
, pp. 425-432
-
-
Rabbani, N.1
Thornalley, P.J.2
-
18
-
-
77956522537
-
Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance
-
P.J. Thornalley, S. Waris, T. Fleming, T. Santarius, S.J. Larkin, B.M. Winklhofer-Roob, M.R. Stratton, and N. Rabbani Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance Nucleic Acids Res. 38 2010 5432 5442
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 5432-5442
-
-
Thornalley, P.J.1
Waris, S.2
Fleming, T.3
Santarius, T.4
Larkin, S.J.5
Winklhofer-Roob, B.M.6
Stratton, M.R.7
Rabbani, N.8
-
20
-
-
84863338358
-
HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells
-
H. Zhang, H. Li, H.S. Xi, and S. Li HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells Blood 119 2012 2595 2607
-
(2012)
Blood
, vol.119
, pp. 2595-2607
-
-
Zhang, H.1
Li, H.2
Xi, H.S.3
Li, S.4
-
21
-
-
0023874677
-
Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide
-
P.A. Hyslop, D.B. Hinshaw, W.A. Halsey, and I.U. Shraufstatter Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide J. Biol. Chem. 263 1988 1665 1675
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 1665-1675
-
-
Hyslop, P.A.1
Hinshaw, D.B.2
Halsey, W.A.3
Shraufstatter, I.U.4
-
22
-
-
0033567419
-
Accumulation of α-oxoaldehydes during oxidative stress. A role in cytotoxicity
-
E.A. Abordo, H.S. Minhas, and P.J. Thornalley Accumulation of α-oxoaldehydes during oxidative stress. A role in cytotoxicity Biochem. Pharmacol. 58 1999 641 648
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 641-648
-
-
Abordo, E.A.1
Minhas, H.S.2
Thornalley, P.J.3
-
23
-
-
42249088093
-
Reconciling the chemistry and biology of reactive oxygen species
-
C.C. Winterbourn Reconciling the chemistry and biology of reactive oxygen species Nat. Chem. Biol. 4 2008 278 286
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 278-286
-
-
Winterbourn, C.C.1
-
24
-
-
84883420686
-
Aging-dependent reduction in glyoxalase 1 delays wound healing
-
T.H. Fleming, T.M. Theilen, J. Masania, M. Wunderle, J. Karimi, S. Vittas, R. Bernauer, A. Bierhaus, N. Rabbani, P.J. Thornalley, J. Kroll, J. Tyedmers, R. Nawrotzki, S. Herzig, M. Brownlee, and P.P. Nawroth Aging-dependent reduction in glyoxalase 1 delays wound healing Gerontology 59 2013 427 437
-
(2013)
Gerontology
, vol.59
, pp. 427-437
-
-
Fleming, T.H.1
Theilen, T.M.2
Masania, J.3
Wunderle, M.4
Karimi, J.5
Vittas, S.6
Bernauer, R.7
Bierhaus, A.8
Rabbani, N.9
Thornalley, P.J.10
Kroll, J.11
Tyedmers, J.12
Nawrotzki, R.13
Herzig, S.14
Brownlee, M.15
Nawroth, P.P.16
-
25
-
-
68849085910
-
Quantitative measurement of specific biomarkers for protein oxidation, nitration and glycation in Arabidopsis leaves
-
U. Bechtold, N. Rabbani, P.M. Mullineaux, and P.J. Thornalley Quantitative measurement of specific biomarkers for protein oxidation, nitration and glycation in Arabidopsis leaves Plant J. 59 2009 661 671
-
(2009)
Plant J.
, vol.59
, pp. 661-671
-
-
Bechtold, U.1
Rabbani, N.2
Mullineaux, P.M.3
Thornalley, P.J.4
-
26
-
-
34247471241
-
A meta-analysis of quantitative trait loci associated with body weight and adiposity in mice
-
S. Wuschke, S. Dahm, C. Schmidt, H.G. Joost, and H. Al Hasani A meta-analysis of quantitative trait loci associated with body weight and adiposity in mice Int. J. Obes. 31 2006 829 841
-
(2006)
Int. J. Obes.
, vol.31
, pp. 829-841
-
-
Wuschke, S.1
Dahm, S.2
Schmidt, C.3
Joost, H.G.4
Al Hasani, H.5
-
27
-
-
0025852493
-
Use of the robust sib-pair method to screen for single-locus, multiple-locus, and pleiotropic effects: Application to traits related to hypertension
-
A.F. Wilson, R.C. Elston, L.D. Tran, and R.M. Siervogel Use of the robust sib-pair method to screen for single-locus, multiple-locus, and pleiotropic effects: application to traits related to hypertension Amer. J. Hum. Genet. 48 1991 862 872
-
(1991)
Amer. J. Hum. Genet.
, vol.48
, pp. 862-872
-
-
Wilson, A.F.1
Elston, R.C.2
Tran, L.D.3
Siervogel, R.M.4
-
28
-
-
84923269345
-
Glyoxalase-1 overexpression reduces body weight and adipokine expression, and improves insulin sensitivity in high-fat diet-induced obese mice
-
D. Maessen, O. Brouwers, T. Miyata, C. Stehouwer, and C. Schalkwijk Glyoxalase-1 overexpression reduces body weight and adipokine expression, and improves insulin sensitivity in high-fat diet-induced obese mice Diabetologia 57 Suppl. 1 2014 713
-
(2014)
Diabetologia
, vol.57
, pp. 713
-
-
Maessen, D.1
Brouwers, O.2
Miyata, T.3
Stehouwer, C.4
Schalkwijk, C.5
-
29
-
-
84862020461
-
Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy
-
A. Bierhaus, T. Fleming, S. Stoyanov, A. Leffler, A. Babes, C. Neacsu, S.K. Sauer, M. Eberhardt, M. Schnolzer, F. Lasischka, W.L. Neuhuber, T.I. Kichko, I. Konrade, R. Elvert, W. Mier, V. Pirags, I.K. Lukic, M. Morcos, T. Dehmer, N. Rabbani, P.J. Thornalley, D. Edelstein, C. Nau, J. Forbes, P.M. Humpert, M. Schwaninger, D. Ziegler, D.M. Stern, M.E. Cooper, U. Haberkorn, M. Brownlee, P.W. Reeh, and P.P. Nawroth Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy Nat. Med. 18 2012 926 933
-
(2012)
Nat. Med.
, vol.18
, pp. 926-933
-
-
Bierhaus, A.1
Fleming, T.2
Stoyanov, S.3
Leffler, A.4
Babes, A.5
Neacsu, C.6
Sauer, S.K.7
Eberhardt, M.8
Schnolzer, M.9
Lasischka, F.10
Neuhuber, W.L.11
Kichko, T.I.12
Konrade, I.13
Elvert, R.14
Mier, W.15
Pirags, V.16
Lukic, I.K.17
Morcos, M.18
Dehmer, T.19
Rabbani, N.20
Thornalley, P.J.21
Edelstein, D.22
Nau, C.23
Forbes, J.24
Humpert, P.M.25
Schwaninger, M.26
Ziegler, D.27
Stern, D.M.28
Cooper, M.E.29
Haberkorn, U.30
Brownlee, M.31
Reeh, P.W.32
Nawroth, P.P.33
more..
-
30
-
-
84897491156
-
The proinflammatory cytokine high-mobility group box-1 mediates retinal neuropathy induced by diabetes
-
A.M. Abu El-Asrar, M. Mairaj Siddiquei, M.I. Nawaz, K. Geboes, and G. Mohammad The proinflammatory cytokine high-mobility group box-1 mediates retinal neuropathy induced by diabetes Mediat. Inflamm. 2014 2014 10
-
(2014)
Mediat. Inflamm.
, vol.2014
, pp. 10
-
-
Abu El-Asrar, A.M.1
Mairaj Siddiquei, M.2
Nawaz, M.I.3
Geboes, K.4
Mohammad, G.5
-
31
-
-
84891772173
-
Knockdown of glyoxalase 1 mimics diabetic nephropathy in nondiabetic mice
-
F. Giacco, X. Du, V.D. D'Agati, R. Milne, G. Sui, M. Geoffrion, and M. Brownlee Knockdown of glyoxalase 1 mimics diabetic nephropathy in nondiabetic mice Diabetes 63 2014 291 299
-
(2014)
Diabetes
, vol.63
, pp. 291-299
-
-
Giacco, F.1
Du, X.2
D'Agati, V.D.3
Milne, R.4
Sui, G.5
Geoffrion, M.6
Brownlee, M.7
-
32
-
-
84856729229
-
Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology
-
A.K. Berner, O. Brouwers, R. Pringle, I. Klaassen, L. Colhoun, C. McVicar, S. Brockbank, J.W. Curry, T. Miyata, M. Brownlee, R.O. Schlingemann, C. Schalkwijk, and A.W. Stitt Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology Diabetologia 55 2012 845 854
-
(2012)
Diabetologia
, vol.55
, pp. 845-854
-
-
Berner, A.K.1
Brouwers, O.2
Pringle, R.3
Klaassen, I.4
Colhoun, L.5
McVicar, C.6
Brockbank, S.7
Curry, J.W.8
Miyata, T.9
Brownlee, M.10
Schlingemann, R.O.11
Schalkwijk, C.12
Stitt, A.W.13
-
33
-
-
22444445653
-
Profound mishandling of protein glycation degradation products in uremia and dialysis
-
S. Agalou, N. Ahmed, R. Babaei-Jadidi, A. Dawnay, and P.J. Thornalley Profound mishandling of protein glycation degradation products in uremia and dialysis J. Am. Soc. Nephrol. 16 2005 1471 1485
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 1471-1485
-
-
Agalou, S.1
Ahmed, N.2
Babaei-Jadidi, R.3
Dawnay, A.4
Thornalley, P.J.5
-
34
-
-
35349015773
-
Protein glycation, oxidation and nitration free adduct accumulation after bilateral nephrectomy and ureteral ligation
-
N. Rabbani, K. Sebekova, K. Sebekova Jr., A. Heidland, and P.J. Thornalley Protein glycation, oxidation and nitration free adduct accumulation after bilateral nephrectomy and ureteral ligation Kidney Intern. 72 2007 1113 1121
-
(2007)
Kidney Intern.
, vol.72
, pp. 1113-1121
-
-
Rabbani, N.1
Sebekova, K.2
Sebekova, Jr.K.3
Heidland, A.4
Thornalley, P.J.5
-
35
-
-
81255201280
-
Glyoxalase i retards renal senescence
-
Y. Ikeda, R. Inagi, T. Miyata, R. Nagai, M. Arai, M. Miyashita, M. Itokawa, T. Fujita, and M. Nangaku Glyoxalase I retards renal senescence Amer. J. Pathol. 179 2011 2810 2821
-
(2011)
Amer. J. Pathol.
, vol.179
, pp. 2810-2821
-
-
Ikeda, Y.1
Inagi, R.2
Miyata, T.3
Nagai, R.4
Arai, M.5
Miyashita, M.6
Itokawa, M.7
Fujita, T.8
Nangaku, M.9
-
36
-
-
80052096203
-
Conversion of low density lipoprotein to the pro-atherogenic form by methylglyoxal with increased arterial proteoglycan binding and aortal retention
-
N. Rabbani, L. Godfrey, M. Xue, F. Shaheen, M. Geoffrion, R. Milne, and P.J. Thornalley Conversion of low density lipoprotein to the pro-atherogenic form by methylglyoxal with increased arterial proteoglycan binding and aortal retention Diabetes 60 2011 1973 1980
-
(2011)
Diabetes
, vol.60
, pp. 1973-1980
-
-
Rabbani, N.1
Godfrey, L.2
Xue, M.3
Shaheen, F.4
Geoffrion, M.5
Milne, R.6
Thornalley, P.J.7
-
37
-
-
84923279572
-
Arginine-directed glycation and decreased HDL plasma concentration and functionality
-
L. Godfrey, N. Yamada-Fowler, J.A. Smith, P.J. Thornalley, and N. Rabbani Arginine-directed glycation and decreased HDL plasma concentration and functionality Nutr. diabetes 4 2014 e134
-
(2014)
Nutr. Diabetes
, vol.4
, pp. e134
-
-
Godfrey, L.1
Yamada-Fowler, N.2
Smith, J.A.3
Thornalley, P.J.4
Rabbani, N.5
-
38
-
-
84908632142
-
Dicarbonyl stress in the absence of hyperglycemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes
-
C. Tikellis, R.J. Pickering, D. Tsorotes, O. Huet, M.E. Cooper, K. Jandeleit-Dahm, and M.C. Thomas Dicarbonyl stress in the absence of hyperglycemia increases endothelial inflammation and atherogenesis similar to that observed in diabetes Diabetes 63 2014 3915 3925
-
(2014)
Diabetes
, vol.63
, pp. 3915-3925
-
-
Tikellis, C.1
Pickering, R.J.2
Tsorotes, D.3
Huet, O.4
Cooper, M.E.5
Jandeleit-Dahm, K.6
Thomas, M.C.7
-
39
-
-
84905491435
-
A.D.G.-W.R. The Coronary, C. Meta-Analysis, Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease
-
V.-P. Mäkinen, M. Civelek, Q. Meng, B. Zhang, J. Zhu, C. Levian, T. Huan, A.V. Segrè, S. Ghosh, J. Vivar, M. Nikpay, A.F.R. Stewart, C.P. Nelson, C. Willenborg, J. Erdmann, S. Blakenberg, C.J. O'Donnell, W. März, R. Laaksonen, S.E. Epstein, S. Kathiresan, S.H. Shah, S.L. Hazen, M.P. Reilly, A.J. Lusis, N.J. Samani, H. Schunkert, T. Quertermous, R. McPherson, X. Yang, T.L. Assimes A.D.G.-W.R. the Coronary, C. Meta-Analysis Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease PLoS Genet. 10 2014 e1004502
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004502
-
-
Mäkinen, V.-P.1
Civelek, M.2
Meng, Q.3
Zhang, B.4
Zhu, J.5
Levian, C.6
Huan, T.7
Segrè, A.V.8
Ghosh, S.9
Vivar, J.10
Nikpay, M.11
Stewart, A.F.R.12
Nelson, C.P.13
Willenborg, C.14
Erdmann, J.15
Blakenberg, S.16
O'Donnell, C.J.17
März, W.18
Laaksonen, R.19
Epstein, S.E.20
Kathiresan, S.21
Shah, S.H.22
Hazen, S.L.23
Reilly, M.P.24
Lusis, A.J.25
Samani, N.J.26
Schunkert, H.27
Quertermous, T.28
McPherson, R.29
Yang, X.30
Assimes, T.L.31
more..
-
40
-
-
56349121125
-
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer
-
L. Zender, W. Xue, J. Zuber, C.P. Semighini, A. Krasnitz, B. Ma, P. Zender, S. Kubicka, J.M. Luk, P. Schirmacher, W. Richard McCombie, M. Wigler, J. Hicks, G.J. Hannon, S. Powers, and S.W. Lowe An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer Cell 135 2008 852 864
-
(2008)
Cell
, vol.135
, pp. 852-864
-
-
Zender, L.1
Xue, W.2
Zuber, J.3
Semighini, C.P.4
Krasnitz, A.5
Ma, B.6
Zender, P.7
Kubicka, S.8
Luk, J.M.9
Schirmacher, P.10
Richard McCombie, W.11
Wigler, M.12
Hicks, J.13
Hannon, G.J.14
Powers, S.15
Lowe, S.W.16
-
41
-
-
77953513144
-
GLO1-A novel amplified gene in human cancer
-
T. Santarius, G.R. Bignell, C.D. Greenan, S. Widaa, L. Chen, C.L. Mahoney, A. Butler, S. Edkins, S. Waris, P.J. Thornalley, P.A. Futreal, and M.R. Stratton GLO1-A novel amplified gene in human cancer Genes Chromsomes Cancer 49 2010 711 725
-
(2010)
Genes Chromsomes Cancer
, vol.49
, pp. 711-725
-
-
Santarius, T.1
Bignell, G.R.2
Greenan, C.D.3
Widaa, S.4
Chen, L.5
Mahoney, C.L.6
Butler, A.7
Edkins, S.8
Waris, S.9
Thornalley, P.J.10
Futreal, P.A.11
Stratton, M.R.12
-
42
-
-
51649130168
-
Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
-
T. Shibata, T. Ohta, K.I. Tong, A. Kokubu, R. Odogawa, K. Tsuta, H. Asamura, M. Yamamoto, and S. Hirohashi Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy Proc. Natl. Acad. Sci. U.S.A 105 2008 13568 13573
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 13568-13573
-
-
Shibata, T.1
Ohta, T.2
Tong, K.I.3
Kokubu, A.4
Odogawa, R.5
Tsuta, K.6
Asamura, H.7
Yamamoto, M.8
Hirohashi, S.9
-
43
-
-
77953304746
-
Enhanced carbonyl stress in a subpopulation of schizophrenia
-
M. Arai, H. Yuzawa, I. Nohara, T. Ohnishi, N. Obata, Y. Iwayama, S. Haga, T. Toyota, H. Ujike, M. Arai, T. Ichikawa, A. Nishida, Y. Tanaka, A. Furukawa, Y. Aikawa, O. Kuroda, K. Niizato, R. Izawa, K. Nakamura, N. Mori, D. Matsuzawa, K. Hashimoto, M. Iyo, I. Sora, M. Matsushita, Y. Okazaki, T. Yoshikawa, T. Miyata, and M. Itokawa Enhanced carbonyl stress in a subpopulation of schizophrenia Arch. Gen. Psychiatry 67 2010 589 597
-
(2010)
Arch. Gen. Psychiatry
, vol.67
, pp. 589-597
-
-
Arai, M.1
Yuzawa, H.2
Nohara, I.3
Ohnishi, T.4
Obata, N.5
Iwayama, Y.6
Haga, S.7
Toyota, T.8
Ujike, H.9
Arai, M.10
Ichikawa, T.11
Nishida, A.12
Tanaka, Y.13
Furukawa, A.14
Aikawa, Y.15
Kuroda, O.16
Niizato, K.17
Izawa, R.18
Nakamura, K.19
Mori, N.20
Matsuzawa, D.21
Hashimoto, K.22
Iyo, M.23
Sora, I.24
Matsushita, M.25
Okazaki, Y.26
Yoshikawa, T.27
Miyata, T.28
Itokawa, M.29
more..
-
44
-
-
79951581055
-
Alpha-synuclein deficiency leads to increased glyoxalase i expression and glycation stress
-
A. Kurz, N. Rabbani, M. Walter, M. Bonin, P.J. Thornalley, G. Auburger, and S. Gispert Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress Cell Mol. Life Sci. 68 2011 721 733
-
(2011)
Cell Mol. Life Sci.
, vol.68
, pp. 721-733
-
-
Kurz, A.1
Rabbani, N.2
Walter, M.3
Bonin, M.4
Thornalley, P.J.5
Auburger, G.6
Gispert, S.7
-
45
-
-
13244270042
-
Protein glycation, oxidation and nitration marker residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment
-
N. Ahmed, U. Ahmed, P.J. Thornalley, K. Hager, G.A. Fleischer, and G. Munch Protein glycation, oxidation and nitration marker residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment J. Neurochem. 92 2004 255 263
-
(2004)
J. Neurochem.
, vol.92
, pp. 255-263
-
-
Ahmed, N.1
Ahmed, U.2
Thornalley, P.J.3
Hager, K.4
Fleischer, G.A.5
Munch, G.6
-
46
-
-
33751330181
-
Age- and stage-dependent glyoxalase i expression and its activity in normal and Alzheimer's disease brains
-
B. Kuhla, K. Boeck, A. Schmidt, V. Ogunlade, T. Arendt, G. Munch, and H.J. Luth Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains Neurobiol. Aging 28 2007 29 41
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 29-41
-
-
Kuhla, B.1
Boeck, K.2
Schmidt, A.3
Ogunlade, V.4
Arendt, T.5
Munch, G.6
Luth, H.J.7
-
47
-
-
0010480577
-
Anti-malarial activity in vitro of the glyoxalase i inhibitor diester, S-p-bromobenzylglutathione diethyl ester
-
P.J. Thornalley, M. Strath, and R.J.M. Wilson Anti-malarial activity in vitro of the glyoxalase I inhibitor diester, S-p-bromobenzylglutathione diethyl ester Biochem. Pharmacol. 268 1994 14189 14825
-
(1994)
Biochem. Pharmacol.
, vol.268
, pp. 14189-14825
-
-
Thornalley, P.J.1
Strath, M.2
Wilson, R.J.M.3
-
48
-
-
84885479125
-
High-dose thiamine supplementation improves glucose tolerance in hyperglycemic individuals: A randomized, double-blind cross-over trial
-
F. Alaei Shahmiri, M.J. Soares, Y. Zhao, and J. Sherriff High-dose thiamine supplementation improves glucose tolerance in hyperglycemic individuals: a randomized, double-blind cross-over trial Eur. J. Nutr. 52 2013 1821 1824
-
(2013)
Eur. J. Nutr.
, vol.52
, pp. 1821-1824
-
-
Alaei Shahmiri, F.1
Soares, M.J.2
Zhao, Y.3
Sherriff, J.4
-
49
-
-
58149467253
-
High dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: A pilot randomised, double-blind, placebo-controlled study
-
N. Rabbani, S. Shahzad Alam, S. Riaz, J.R. Larkin, M.W. Akhtar, T. Shafi, and P.J. Thornalley High dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a pilot randomised, double-blind, placebo-controlled study Diabetologia 52 2009 208 212
-
(2009)
Diabetologia
, vol.52
, pp. 208-212
-
-
Rabbani, N.1
Shahzad Alam, S.2
Riaz, S.3
Larkin, J.R.4
Akhtar, M.W.5
Shafi, T.6
Thornalley, P.J.7
-
50
-
-
84858307371
-
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress responsive defence against dicarbonyl glycation
-
M. Xue, N. Rabbani, H. Momiji, P. Imbasi, M.M. Anwar, N.R. Kitteringham, B.K. Park, T. Souma, T. Moriguchi, M. Yamamoto, and P.J. Thornalley Transcriptional control of glyoxalase 1 by Nrf2 provides a stress responsive defence against dicarbonyl glycation Biochem. J. 443 2012 213 222
-
(2012)
Biochem. J.
, vol.443
, pp. 213-222
-
-
Xue, M.1
Rabbani, N.2
Momiji, H.3
Imbasi, P.4
Anwar, M.M.5
Kitteringham, N.R.6
Park, B.K.7
Souma, T.8
Moriguchi, T.9
Yamamoto, M.10
Thornalley, P.J.11
|