Gedunin binds to myeloid differentiation protein 2 and impairs lipopolysaccharide-induced toll-like receptor 4 signaling in macrophages s

Molecular Pharmacology

Volumn 88, Issue 5, 2015, Pages 949-961

  Borges, Perla Villani ^a   Moret, Katelim Hottz ^a   Maya Monteiro, Clarissa Menezes ^a   Souza Silva, Franklin ^a   Alves, Carlos Roberto ^a   Batista, Paulo Ricardo ^a   Caffarena, Ernesto Raúl ^a   Pacheco, Patrícia ^a   Das Graças Henriques, Maria ^a   Penido, Carmen ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; CYCLOOXYGENASE 2; GEDUNIN; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1; INTERLEUKIN 10; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE; PROTEIN MD 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; HEAT SHOCK PROTEIN 90; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; LIMONOID; LIPOPOLYSACCHARIDE; LY96 PROTEIN, MOUSE; MEMBRANE PROTEIN; PROSTAGLANDIN E2; TIRAP PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BINDING SITE; BONE MARROW DERIVED MACROPHAGE; CALCIUM TRANSPORT; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG PROTEIN BINDING; MACROPHAGE ACTIVATION; MOLECULAR DOCKING; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; ACTIVE TRANSPORT; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MACROPHAGE; METABOLISM; PHYSIOLOGY;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BINDING SITES; CELLS, CULTURED; CYTOKINES; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; HSP90 HEAT-SHOCK PROTEINS; LIMONINS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NF-KAPPA B; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84946744400     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.115.098970     Document Type: Article

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