The inhibition of LPS-induced production of inflammatory cytokines by HSP70 involves inactivation of the NF-κB pathway but not the MAPK pathways

Shock

Volumn 26, Issue 3, 2006, Pages 277-284

  Shi, Yongzhong ^a   Tu, Zizhi ^a   Tang, Daolin ^a   Zhang, Huali ^a   Liu, Meidong ^a   Wang, Kangkai ^a   Calderwood, Stuart K ^b   Xiao, Xianzhong ^a  

^a Central South University   (China)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Endotoxin; Heat shock response; Inflammation; Phosphatase; Phosphorylation; Signal pathway

Indexed keywords

CYTOKINE; ENDOTOXIN; HEAT SHOCK PROTEIN 70; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; CYTOKINE RELEASE; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE ACTIVATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HEAT SHOCK RESPONSE; MACROPHAGE ACTIVATION; MEDIATOR RELEASE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; TRANSCRIPTION REGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; CYTOKINES; GENE EXPRESSION; HEAT-SHOCK RESPONSE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33747341005     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000223134.17877.ad     Document Type: Article

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