-
1
-
-
84863793904
-
Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+channel inhibition
-
Al-Owais M.M., Scragg J.L., Dallas M.L., Boycott H.E., Warburton P., Chakrabarty A., Boyle J.P., Peers C. Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+channel inhibition. J. Biol. Chem. 2012, 287:24754-24764.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 24754-24764
-
-
Al-Owais, M.M.1
Scragg, J.L.2
Dallas, M.L.3
Boycott, H.E.4
Warburton, P.5
Chakrabarty, A.6
Boyle, J.P.7
Peers, C.8
-
2
-
-
33644838918
-
Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols
-
Andreadi C.K., Howells L.M., Atherfold P.A., Manson M.M. Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols. Mol. Pharmacol. 2006, 69:1033-1040.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 1033-1040
-
-
Andreadi, C.K.1
Howells, L.M.2
Atherfold, P.A.3
Manson, M.M.4
-
3
-
-
84872183989
-
Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases
-
Barbagallo I., Galvano F., Frigiola A., Cappello F., Riccioni G., Murabito P., D'Orazio N., Torella M., Gazzolo D., Li Volti G. Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases. Antioxid. Redox Signal. 2013, 18:507-521.
-
(2013)
Antioxid. Redox Signal.
, vol.18
, pp. 507-521
-
-
Barbagallo, I.1
Galvano, F.2
Frigiola, A.3
Cappello, F.4
Riccioni, G.5
Murabito, P.6
D'Orazio, N.7
Torella, M.8
Gazzolo, D.9
Li Volti, G.10
-
4
-
-
84861601576
-
Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment
-
Barone E., Di Domenico F., Sultana R., Coccia R., Mancuso C., Perluigi M., Butterfield D.A. Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment. Free Radic. Biol. Med. 2012, 52:2292-2301.
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 2292-2301
-
-
Barone, E.1
Di Domenico, F.2
Sultana, R.3
Coccia, R.4
Mancuso, C.5
Perluigi, M.6
Butterfield, D.A.7
-
5
-
-
55749097776
-
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
-
Basak S., Pookot D., Noonan E.J., Dahiya R. Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function. Mol. Cancer Ther. 2008, 7:3195-3202.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 3195-3202
-
-
Basak, S.1
Pookot, D.2
Noonan, E.J.3
Dahiya, R.4
-
6
-
-
21044452445
-
Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment
-
Berberat P.O., Dambrauskas Z., Gulbinas A., Giese T., Giese N., Kunzli B., Autschbach F., Meuer S., Buchler M.W., Friess H. Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment. Clin. Cancer Res. 2005, 11:3790-3798.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 3790-3798
-
-
Berberat, P.O.1
Dambrauskas, Z.2
Gulbinas, A.3
Giese, T.4
Giese, N.5
Kunzli, B.6
Autschbach, F.7
Meuer, S.8
Buchler, M.W.9
Friess, H.10
-
7
-
-
84864551111
-
Heme oxygenase-1 protects retinal endothelial cells against high glucose- and oxidative/nitrosative stress-induced toxicity
-
Castilho A., Aveleira C.A., Leal E.C., Simoes N.F., Fernandes C.R., Meirinhos R.I., Baptista F.I., Ambrosio A.F. Heme oxygenase-1 protects retinal endothelial cells against high glucose- and oxidative/nitrosative stress-induced toxicity. PLoS One 2012, 7:e42428.
-
(2012)
PLoS One
, vol.7
-
-
Castilho, A.1
Aveleira, C.A.2
Leal, E.C.3
Simoes, N.F.4
Fernandes, C.R.5
Meirinhos, R.I.6
Baptista, F.I.7
Ambrosio, A.F.8
-
8
-
-
84871647827
-
Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis
-
Chang D.J., An H., Kim K.S., Kim H.H., Jung J., Lee J.M., Kim N.J., Han Y.T., Yun H., Lee S., Lee G., Lee J.S., Cha J.H., Park J.H., Park J.W., Lee S.C., Kim S.G., Kim J.H., Lee H.Y., Kim K.W., Suh Y.G. Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis. J. Med. Chem. 2012, 55:10863-10884.
-
(2012)
J. Med. Chem.
, vol.55
, pp. 10863-10884
-
-
Chang, D.J.1
An, H.2
Kim, K.S.3
Kim, H.H.4
Jung, J.5
Lee, J.M.6
Kim, N.J.7
Han, Y.T.8
Yun, H.9
Lee, S.10
Lee, G.11
Lee, J.S.12
Cha, J.H.13
Park, J.H.14
Park, J.W.15
Lee, S.C.16
Kim, S.G.17
Kim, J.H.18
Lee, H.Y.19
Kim, K.W.20
Suh, Y.G.21
more..
-
9
-
-
84881493942
-
Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells
-
Chao C.Y., Lii C.K., Hsu Y.T., Lu C.Y., Liu K.L., Li C.C., Chen H.W. Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells. Carcinogenesis 2013, 34:1843-1851.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1843-1851
-
-
Chao, C.Y.1
Lii, C.K.2
Hsu, Y.T.3
Lu, C.Y.4
Liu, K.L.5
Li, C.C.6
Chen, H.W.7
-
10
-
-
33749235315
-
Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6
-
Chen Y.C., Chow J.M., Lin C.W., Wu C.Y., Shen S.C. Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6. Toxicol. Appl. Pharmacol. 2006, 216:263-273.
-
(2006)
Toxicol. Appl. Pharmacol.
, vol.216
, pp. 263-273
-
-
Chen, Y.C.1
Chow, J.M.2
Lin, C.W.3
Wu, C.Y.4
Shen, S.C.5
-
11
-
-
84886924428
-
Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells
-
Chen H.W., Chao C.Y., Lin L.L., Lu C.Y., Liu K.L., Lii C.K., Li C.C. Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells. Arch. Toxicol. 2013, 87:857-869.
-
(2013)
Arch. Toxicol.
, vol.87
, pp. 857-869
-
-
Chen, H.W.1
Chao, C.Y.2
Lin, L.L.3
Lu, C.Y.4
Liu, K.L.5
Lii, C.K.6
Li, C.C.7
-
12
-
-
39749124150
-
Cytotoxic effects of metal protoporphyrins in glioblastoma cells: roles of albumin, reactive oxygen species, and heme oxygenase-1
-
Chow J.M., Huang G.C., Lin H.Y., Shen S.C., Yang L.Y., Chen Y.C. Cytotoxic effects of metal protoporphyrins in glioblastoma cells: roles of albumin, reactive oxygen species, and heme oxygenase-1. Toxicol. Lett. 2008, 177:97-107.
-
(2008)
Toxicol. Lett.
, vol.177
, pp. 97-107
-
-
Chow, J.M.1
Huang, G.C.2
Lin, H.Y.3
Shen, S.C.4
Yang, L.Y.5
Chen, Y.C.6
-
13
-
-
84455208060
-
Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1beta in osteoarthritic osteoblasts
-
Clerigues V., Guillen M.I., Castejon M.A., Gomar F., Mirabet V., Alcaraz M.J. Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1beta in osteoarthritic osteoblasts. Biochem. Pharmacol. 2012, 83:395-405.
-
(2012)
Biochem. Pharmacol.
, vol.83
, pp. 395-405
-
-
Clerigues, V.1
Guillen, M.I.2
Castejon, M.A.3
Gomar, F.4
Mirabet, V.5
Alcaraz, M.J.6
-
14
-
-
34547795788
-
Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast
-
Cornblatt B.S., Ye L., Dinkova-Kostova A.T., Erb M., Fahey J.W., Singh N.K., Chen M.S., Stierer T., Garrett-Mayer E., Argani P., Davidson N.E., Talalay P., Kensler T.W., Visvanathan K. Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast. Carcinogenesis 2007, 28:1485-1490.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1485-1490
-
-
Cornblatt, B.S.1
Ye, L.2
Dinkova-Kostova, A.T.3
Erb, M.4
Fahey, J.W.5
Singh, N.K.6
Chen, M.S.7
Stierer, T.8
Garrett-Mayer, E.9
Argani, P.10
Davidson, N.E.11
Talalay, P.12
Kensler, T.W.13
Visvanathan, K.14
-
15
-
-
61649098007
-
Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket
-
Donnelly A., Blagg B.S. Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket. Curr. Med. Chem. 2008, 15:2702-2717.
-
(2008)
Curr. Med. Chem.
, vol.15
, pp. 2702-2717
-
-
Donnelly, A.1
Blagg, B.S.2
-
16
-
-
84855427508
-
Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1
-
Furfaro A.L., Macay J.R., Marengo B., Nitti M., Parodi A., Fenoglio D., Marinari U.M., Pronzato M.A., Domenicotti C., Traverso N. Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1. Free Radic. Biol. Med. 2012, 52:488-496.
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 488-496
-
-
Furfaro, A.L.1
Macay, J.R.2
Marengo, B.3
Nitti, M.4
Parodi, A.5
Fenoglio, D.6
Marinari, U.M.7
Pronzato, M.A.8
Domenicotti, C.9
Traverso, N.10
-
17
-
-
77949503424
-
The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition
-
Giommarelli C., Zuco V., Favini E., Pisano C., Dal Piaz F., De Tommasi N., Zunino F. The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition. Cell. Mol. Life Sci. 2010, 67:995-1004.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 995-1004
-
-
Giommarelli, C.1
Zuco, V.2
Favini, E.3
Pisano, C.4
Dal Piaz, F.5
De Tommasi, N.6
Zunino, F.7
-
19
-
-
84864411435
-
Black tea polyphenols induce human leukemic cell cycle arrest by inhibiting Akt signaling: possible involvement of Hsp90, Wnt/beta-catenin signaling and FOXO1
-
Halder B., Das Gupta S., Gomes A. Black tea polyphenols induce human leukemic cell cycle arrest by inhibiting Akt signaling: possible involvement of Hsp90, Wnt/beta-catenin signaling and FOXO1. FEBS J. 2012, 279:2876-2891.
-
(2012)
FEBS J.
, vol.279
, pp. 2876-2891
-
-
Halder, B.1
Das Gupta, S.2
Gomes, A.3
-
20
-
-
28744447937
-
Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase
-
Hill M., Pereira V., Chauveau C., Zagani R., Remy S., Tesson L., Mazal D., Ubillos L., Brion R., Asghar K., Mashreghi M.F., Kotsch K., Moffett J., Doebis C., Seifert M., Boczkowski J., Osinaga E., Anegon I. Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. FASEB J. 2005, 19:1957-1968.
-
(2005)
FASEB J.
, vol.19
, pp. 1957-1968
-
-
Hill, M.1
Pereira, V.2
Chauveau, C.3
Zagani, R.4
Remy, S.5
Tesson, L.6
Mazal, D.7
Ubillos, L.8
Brion, R.9
Asghar, K.10
Mashreghi, M.F.11
Kotsch, K.12
Moffett, J.13
Doebis, C.14
Seifert, M.15
Boczkowski, J.16
Osinaga, E.17
Anegon, I.18
-
21
-
-
84875519144
-
Targeting the molecular chaperone heat shock protein 90 (HSP90): lessons learned and future directions
-
Hong D.S., Banerji U., Tavana B., George G.C., Aaron J., Kurzrock R. Targeting the molecular chaperone heat shock protein 90 (HSP90): lessons learned and future directions. Cancer Treat. Rev. 2013, 39:375-387.
-
(2013)
Cancer Treat. Rev.
, vol.39
, pp. 375-387
-
-
Hong, D.S.1
Banerji, U.2
Tavana, B.3
George, G.C.4
Aaron, J.5
Kurzrock, R.6
-
22
-
-
84857039457
-
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
-
Jhaveri K., Taldone T., Modi S., Chiosis G. Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers. Biochim. Biophys. Acta 2012, 1823:742-755.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 742-755
-
-
Jhaveri, K.1
Taldone, T.2
Modi, S.3
Chiosis, G.4
-
23
-
-
33749019130
-
Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells
-
Keum Y.S., Yu S., Chang P.P., Yuan X., Kim J.H., Xu C., Han J., Agarwal A., Kong A.N. Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells. Cancer Res. 2006, 66:8804-8813.
-
(2006)
Cancer Res.
, vol.66
, pp. 8804-8813
-
-
Keum, Y.S.1
Yu, S.2
Chang, P.P.3
Yuan, X.4
Kim, J.H.5
Xu, C.6
Han, J.7
Agarwal, A.8
Kong, A.N.9
-
24
-
-
42749088840
-
Carbon monoxide decreases the level of iNOS protein and active dimer in IL-1beta-stimulated hepatocytes
-
Kim H.S., Loughran P.A., Billiar T.R. Carbon monoxide decreases the level of iNOS protein and active dimer in IL-1beta-stimulated hepatocytes. Nitric Oxide 2008, 18:256-265.
-
(2008)
Nitric Oxide
, vol.18
, pp. 256-265
-
-
Kim, H.S.1
Loughran, P.A.2
Billiar, T.R.3
-
25
-
-
74249085361
-
Update on Hsp90 inhibitors in clinical trial
-
Kim Y.S., Alarcon S.V., Lee S., Lee M.J., Giaccone G., Neckers L., Trepel J.B. Update on Hsp90 inhibitors in clinical trial. Curr. Top. Med. Chem. 2009, 9:1479-1492.
-
(2009)
Curr. Top. Med. Chem.
, vol.9
, pp. 1479-1492
-
-
Kim, Y.S.1
Alarcon, S.V.2
Lee, S.3
Lee, M.J.4
Giaccone, G.5
Neckers, L.6
Trepel, J.B.7
-
26
-
-
77249158324
-
Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT
-
Lee J.H., Chung I.K. Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT. Cancer Lett. 2010, 290:76-86.
-
(2010)
Cancer Lett.
, vol.290
, pp. 76-86
-
-
Lee, J.H.1
Chung, I.K.2
-
27
-
-
68449083502
-
Overexpression of HO-1 protects against TNF-alpha-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress
-
Lee I.T., Luo S.F., Lee C.W., Wang S.W., Lin C.C., Chang C.C., Chen Y.L., Chau L.Y., Yang C.M. Overexpression of HO-1 protects against TNF-alpha-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress. Am. J. Pathol. 2009, 175:519-532.
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 519-532
-
-
Lee, I.T.1
Luo, S.F.2
Lee, C.W.3
Wang, S.W.4
Lin, C.C.5
Chang, C.C.6
Chen, Y.L.7
Chau, L.Y.8
Yang, C.M.9
-
28
-
-
79956017927
-
Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells
-
Li D., Marchenko N.D., Schulz R., Fischer V., Velasco-Hernandez T., Talos F., Moll U.M. Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells. Mol. Cancer Res. 2011, 9:577-588.
-
(2011)
Mol. Cancer Res.
, vol.9
, pp. 577-588
-
-
Li, D.1
Marchenko, N.D.2
Schulz, R.3
Fischer, V.4
Velasco-Hernandez, T.5
Talos, F.6
Moll, U.M.7
-
29
-
-
79952120959
-
Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: relevance for anti-aging intervention
-
Lima C.F., Pereira-Wilson C., Rattan S.I. Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: relevance for anti-aging intervention. Mol. Nutr. Food Res. 2011, 55:430-442.
-
(2011)
Mol. Nutr. Food Res.
, vol.55
, pp. 430-442
-
-
Lima, C.F.1
Pereira-Wilson, C.2
Rattan, S.I.3
-
30
-
-
34250223064
-
Baicalein inhibition of hydrogen peroxide-induced apoptosis via ROS-dependent heme oxygenase 1 gene expression
-
Lin H.Y., Shen S.C., Lin C.W., Yang L.Y., Chen Y.C. Baicalein inhibition of hydrogen peroxide-induced apoptosis via ROS-dependent heme oxygenase 1 gene expression. Biochim. Biophys. Acta 2007, 1773:1073-1086.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 1073-1086
-
-
Lin, H.Y.1
Shen, S.C.2
Lin, C.W.3
Yang, L.Y.4
Chen, Y.C.5
-
31
-
-
49849103925
-
Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9
-
Lin C.W., Shen S.C., Hou W.C., Yang L.Y., Chen Y.C. Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9. Mol. Cancer Ther. 2008, 7:1195-1206.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1195-1206
-
-
Lin, C.W.1
Shen, S.C.2
Hou, W.C.3
Yang, L.Y.4
Chen, Y.C.5
-
32
-
-
42049109174
-
Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells
-
Lin K., Rockliffe N., Johnson G.G., Sherrington P.D., Pettitt A.R. Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells. Oncogene 2008, 27:2445-2455.
-
(2008)
Oncogene
, vol.27
, pp. 2445-2455
-
-
Lin, K.1
Rockliffe, N.2
Johnson, G.G.3
Sherrington, P.D.4
Pettitt, A.R.5
-
33
-
-
78649767464
-
Reciprocal activation of macrophages and breast carcinoma cells by nitric oxide and colony-stimulating factor-1
-
Lin C.W., Shen S.C., Ko C.H., Lin H.Y., Chen Y.C. Reciprocal activation of macrophages and breast carcinoma cells by nitric oxide and colony-stimulating factor-1. Carcinogenesis 2010, 31:2039-2048.
-
(2010)
Carcinogenesis
, vol.31
, pp. 2039-2048
-
-
Lin, C.W.1
Shen, S.C.2
Ko, C.H.3
Lin, H.Y.4
Chen, Y.C.5
-
34
-
-
49849099361
-
Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities
-
Loboda A., Jazwa A., Grochot-Przeczek A., Rutkowski A.J., Cisowski J., Agarwal A., Jozkowicz A., Dulak J. Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities. Antioxid. Redox Signal. 2008, 10:1767-1812.
-
(2008)
Antioxid. Redox Signal.
, vol.10
, pp. 1767-1812
-
-
Loboda, A.1
Jazwa, A.2
Grochot-Przeczek, A.3
Rutkowski, A.J.4
Cisowski, J.5
Agarwal, A.6
Jozkowicz, A.7
Dulak, J.8
-
35
-
-
10344243547
-
Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures
-
Muller L., Schaupp A., Walerych D., Wegele H., Buchner J. Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures. J. Biol. Chem. 2004, 279:48846-48854.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48846-48854
-
-
Muller, L.1
Schaupp, A.2
Walerych, D.3
Wegele, H.4
Buchner, J.5
-
36
-
-
44149124776
-
Chaperone-dependent stabilization and degradation of p53 mutants
-
Muller P., Hrstka R., Coomber D., Lane D.P., Vojtesek B. Chaperone-dependent stabilization and degradation of p53 mutants. Oncogene 2008, 27:3371-3383.
-
(2008)
Oncogene
, vol.27
, pp. 3371-3383
-
-
Muller, P.1
Hrstka, R.2
Coomber, D.3
Lane, D.P.4
Vojtesek, B.5
-
37
-
-
84879412911
-
C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances
-
Muller P., Ruckova E., Halada P., Coates P.J., Hrstka R., Lane D.P., Vojtesek B. C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances. Oncogene 2013, 32:3101-3110.
-
(2013)
Oncogene
, vol.32
, pp. 3101-3110
-
-
Muller, P.1
Ruckova, E.2
Halada, P.3
Coates, P.J.4
Hrstka, R.5
Lane, D.P.6
Vojtesek, B.7
-
38
-
-
33745074201
-
Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity
-
Nowis D., Legat M., Grzela T., Niderla J., Wilczek E., Wilczynski G.M., Glodkowska E., Mrowka P., Issat T., Dulak J., Jozkowicz A., Was H., Adamek M., Wrzosek A., Nazarewski S., Makowski M., Stoklosa T., Jakobisiak M., Golab J. Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity. Oncogene 2006, 25:3365-3374.
-
(2006)
Oncogene
, vol.25
, pp. 3365-3374
-
-
Nowis, D.1
Legat, M.2
Grzela, T.3
Niderla, J.4
Wilczek, E.5
Wilczynski, G.M.6
Glodkowska, E.7
Mrowka, P.8
Issat, T.9
Dulak, J.10
Jozkowicz, A.11
Was, H.12
Adamek, M.13
Wrzosek, A.14
Nazarewski, S.15
Makowski, M.16
Stoklosa, T.17
Jakobisiak, M.18
Golab, J.19
-
39
-
-
67650093930
-
Heme oxygenase-1 and its metabolites affect pancreatic tumor growth in vivo
-
Nuhn P., Kunzli B.M., Hennig R., Mitkus T., Ramanauskas T., Nobiling R., Meuer S.C., Friess H., Berberat P.O. Heme oxygenase-1 and its metabolites affect pancreatic tumor growth in vivo. Mol. Cancer 2009, 8:37.
-
(2009)
Mol. Cancer
, vol.8
, pp. 37
-
-
Nuhn, P.1
Kunzli, B.M.2
Hennig, R.3
Mitkus, T.4
Ramanauskas, T.5
Nobiling, R.6
Meuer, S.C.7
Friess, H.8
Berberat, P.O.9
-
40
-
-
0037077230
-
Akt enhances Mdm2-mediated ubiquitination and degradation of p53
-
Ogawara Y., Kishishita S., Obata T., Isazawa Y., Suzuki T., Tanaka K., Masuyama N., Gotoh Y. Akt enhances Mdm2-mediated ubiquitination and degradation of p53. J. Biol. Chem. 2002, 277:21843-21850.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21843-21850
-
-
Ogawara, Y.1
Kishishita, S.2
Obata, T.3
Isazawa, Y.4
Suzuki, T.5
Tanaka, K.6
Masuyama, N.7
Gotoh, Y.8
-
41
-
-
34347256360
-
Structural basis for depletion of heat shock protein 90 client proteins by deguelin
-
Oh S.H., Woo J.K., Yazici Y.D., Myers J.N., Kim W.Y., Jin Q., Hong S.S., Park H.J., Suh Y.G., Kim K.W., Hong W.K., Lee H.Y. Structural basis for depletion of heat shock protein 90 client proteins by deguelin. J. Natl. Cancer Inst. 2007, 99:949-961.
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 949-961
-
-
Oh, S.H.1
Woo, J.K.2
Yazici, Y.D.3
Myers, J.N.4
Kim, W.Y.5
Jin, Q.6
Hong, S.S.7
Park, H.J.8
Suh, Y.G.9
Kim, K.W.10
Hong, W.K.11
Lee, H.Y.12
-
42
-
-
73849099768
-
HO-1 and CO decrease platelet-derived growth factor-induced vascular smooth muscle cell migration via inhibition of Nox1
-
Rodriguez A.I., Gangopadhyay A., Kelley E.E., Pagano P.J., Zuckerbraun B.S., Bauer P.M. HO-1 and CO decrease platelet-derived growth factor-induced vascular smooth muscle cell migration via inhibition of Nox1. Arterioscler. Thromb. Vasc. Biol. 2010, 30:98-104.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 98-104
-
-
Rodriguez, A.I.1
Gangopadhyay, A.2
Kelley, E.E.3
Pagano, P.J.4
Zuckerbraun, B.S.5
Bauer, P.M.6
-
43
-
-
84856358836
-
Identification of heat shock protein 90 inhibitors to sensitize drug resistant side population tumor cells using a cell based assay platform
-
Sobhan P.K., Seervi M., Joseph J., Chandrika B.B., Varghese S., Santhoshkumar T.R., Radhakrishna Pillai M. Identification of heat shock protein 90 inhibitors to sensitize drug resistant side population tumor cells using a cell based assay platform. Cancer Lett. 2012, 317:78-88.
-
(2012)
Cancer Lett.
, vol.317
, pp. 78-88
-
-
Sobhan, P.K.1
Seervi, M.2
Joseph, J.3
Chandrika, B.B.4
Varghese, S.5
Santhoshkumar, T.R.6
Radhakrishna Pillai, M.7
-
44
-
-
58149340657
-
Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma
-
Solit D.B., Osman I., Polsky D., Panageas K.S., Daud A., Goydos J.S., Teitcher J., Wolchok J.D., Germino F.J., Krown S.E., Coit D., Rosen N., Chapman P.B. Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma. Clin. Cancer Res. 2008, 14:8302-8307.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 8302-8307
-
-
Solit, D.B.1
Osman, I.2
Polsky, D.3
Panageas, K.S.4
Daud, A.5
Goydos, J.S.6
Teitcher, J.7
Wolchok, J.D.8
Germino, F.J.9
Krown, S.E.10
Coit, D.11
Rosen, N.12
Chapman, P.B.13
-
45
-
-
77953916528
-
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
-
Taipale M., Jarosz D.F., Lindquist S. HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat. Rev. Mol. Cell Biol. 2010, 11:515-528.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 515-528
-
-
Taipale, M.1
Jarosz, D.F.2
Lindquist, S.3
-
46
-
-
84865798436
-
Tomato powder impedes the development of azoxymethane-induced colorectal cancer in rats through suppression of COX-2 expression via NF-kappaB and regulating Nrf2/HO-1 pathway
-
Tuzcu M., Aslan A., Tuzcu Z., Yabas M., Bahcecioglu I.H., Ozercan I.H., Kucuk O., Sahin K. Tomato powder impedes the development of azoxymethane-induced colorectal cancer in rats through suppression of COX-2 expression via NF-kappaB and regulating Nrf2/HO-1 pathway. Mol. Nutr. Food Res. 2012, 56:1477-1481.
-
(2012)
Mol. Nutr. Food Res.
, vol.56
, pp. 1477-1481
-
-
Tuzcu, M.1
Aslan, A.2
Tuzcu, Z.3
Yabas, M.4
Bahcecioglu, I.H.5
Ozercan, I.H.6
Kucuk, O.7
Sahin, K.8
-
47
-
-
0037449734
-
Phosphorylation and hsp90 binding mediate heat shock stabilization of p53
-
Wang C., Chen J. Phosphorylation and hsp90 binding mediate heat shock stabilization of p53. J. Biol. Chem. 2003, 278:2066-2071.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2066-2071
-
-
Wang, C.1
Chen, J.2
-
48
-
-
84859802748
-
Heme oxygenase-1 in inflammation and cardiovascular disease
-
Wu M.L., Ho Y.C., Lin C.Y., Yet S.F. Heme oxygenase-1 in inflammation and cardiovascular disease. Am. J. Cardiovasc. Dis. 2011, 1:150-158.
-
(2011)
Am. J. Cardiovasc. Dis.
, vol.1
, pp. 150-158
-
-
Wu, M.L.1
Ho, Y.C.2
Lin, C.Y.3
Yet, S.F.4
-
49
-
-
84055190677
-
Low-dose Hsp90 inhibitors tumor-selectively sensitize bladder cancer cells to chemoradiotherapy
-
Yoshida S., Koga F., Tatokoro M., Kawakami S., Fujii Y., Kumagai J., Neckers L., Kihara K. Low-dose Hsp90 inhibitors tumor-selectively sensitize bladder cancer cells to chemoradiotherapy. Cell Cycle 2011, 10:4291-4299.
-
(2011)
Cell Cycle
, vol.10
, pp. 4291-4299
-
-
Yoshida, S.1
Koga, F.2
Tatokoro, M.3
Kawakami, S.4
Fujii, Y.5
Kumagai, J.6
Neckers, L.7
Kihara, K.8
-
50
-
-
80052023055
-
Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90
-
Zhao M., Ma J., Zhu H.Y., Zhang X.H., Du Z.Y., Xu Y.J., Yu X.D. Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90. Mol. Cancer 2011, 10:104.
-
(2011)
Mol. Cancer
, vol.10
, pp. 104
-
-
Zhao, M.1
Ma, J.2
Zhu, H.Y.3
Zhang, X.H.4
Du, Z.Y.5
Xu, Y.J.6
Yu, X.D.7
-
51
-
-
81855183855
-
Heme oxygenase-1: a molecular brake on hepatocellular carcinoma cell migration
-
Zou C., Zhang H., Li Q., Xiao H., Yu L., Ke S., Zhou L., Liu W., Wang W., Huang H., Ma N., Liu Q., Wang X., Zhao W., Zhou H., Gao X. Heme oxygenase-1: a molecular brake on hepatocellular carcinoma cell migration. Carcinogenesis 2011, 32:1840-1848.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1840-1848
-
-
Zou, C.1
Zhang, H.2
Li, Q.3
Xiao, H.4
Yu, L.5
Ke, S.6
Zhou, L.7
Liu, W.8
Wang, W.9
Huang, H.10
Ma, N.11
Liu, Q.12
Wang, X.13
Zhao, W.14
Zhou, H.15
Gao, X.16
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