-
1
-
-
78049526283
-
The role of intestinal endotoxin in liver injury: a long and evolving history
-
Nolan JP. The role of intestinal endotoxin in liver injury: a long and evolving history. HEPATOLOGY 2010; 52: 1829-1835.
-
(2010)
HEPATOLOGY
, vol.52
, pp. 1829-1835
-
-
Nolan, J.P.1
-
2
-
-
67349139869
-
Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model
-
Kudo H, Takahara T, Yata Y, Kawai K, Zhang W, Sugiyama T. Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model. J Hepatol 2009; 51: 168-175.
-
(2009)
J Hepatol
, vol.51
, pp. 168-175
-
-
Kudo, H.1
Takahara, T.2
Yata, Y.3
Kawai, K.4
Zhang, W.5
Sugiyama, T.6
-
3
-
-
0001513966
-
Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis
-
Yang SQ, Lin HZ, Lane MD, Clemens M, Diehl AM. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci U S A 1997; 94: 2557-2562.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 2557-2562
-
-
Yang, S.Q.1
Lin, H.Z.2
Lane, M.D.3
Clemens, M.4
Diehl, A.M.5
-
4
-
-
0034108596
-
Role of kupffer cells and gut-derived endotoxins in alcoholic liver injury
-
Enomoto N, Ikejima K, Bradford BU, Rivera CA, Kono H, Goto M, et al. Role of kupffer cells and gut-derived endotoxins in alcoholic liver injury. J Gastroenterol Hepatol 2000; 15( Suppl): D20-D25.
-
(2000)
J Gastroenterol Hepatol
, vol.15
, Issue.SUPPL.
-
-
Enomoto, N.1
Ikejima, K.2
Bradford, B.U.3
Rivera, C.A.4
Kono, H.5
Goto, M.6
-
5
-
-
0037087374
-
Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice
-
Uesugi T, Froh M, Arteel GE, Bradford BU, Wheeler MD, Gabele E, et al. Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice. J Immunol 2002; 168: 2963-2969.
-
(2002)
J Immunol
, vol.168
, pp. 2963-2969
-
-
Uesugi, T.1
Froh, M.2
Arteel, G.E.3
Bradford, B.U.4
Wheeler, M.D.5
Gabele, E.6
-
6
-
-
0034834253
-
Long-term alcohol exposure changes sensitivity of rat kupffer cells to lipopolysaccharide
-
Enomoto N, Schemmer P, Ikejima K, Takei Y, Sato N, Brenner DA, Thurman RG. Long-term alcohol exposure changes sensitivity of rat kupffer cells to lipopolysaccharide. Alcohol Clin Exp Res 2001; 25: 1360-1367.
-
(2001)
Alcohol Clin Exp Res
, vol.25
, pp. 1360-1367
-
-
Enomoto, N.1
Schemmer, P.2
Ikejima, K.3
Takei, Y.4
Sato, N.5
Brenner, D.A.6
Thurman, R.G.7
-
7
-
-
78649724771
-
Lipopolysaccharide binding protein inhibitory peptide protects against acetaminophen-induced hepatotoxicity
-
Su GL, Hoesel LM, Bayliss J, Hemmila MR, Wang SC. Lipopolysaccharide binding protein inhibitory peptide protects against acetaminophen-induced hepatotoxicity. Am J Physiol Gastrointest Liver Physiol 2010; 299: G1319-G1325.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.299
-
-
Su, G.L.1
Hoesel, L.M.2
Bayliss, J.3
Hemmila, M.R.4
Wang, S.C.5
-
8
-
-
0035491305
-
Lung and liver injury following hepatic ischemia/reperfusion in the rat is increased by exogenous lipopolysaccharide which also increases hepatic TNF production in vivo and in vitro
-
Colletti LM, Green M. Lung and liver injury following hepatic ischemia/reperfusion in the rat is increased by exogenous lipopolysaccharide which also increases hepatic TNF production in vivo and in vitro. Shock 2001; 16: 312-319.
-
(2001)
Shock
, vol.16
, pp. 312-319
-
-
Colletti, L.M.1
Green, M.2
-
9
-
-
77957948007
-
Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents
-
Yu LX, Yan HX, Liu Q, Yang W, Wu HP, Dong W, et al. Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents. HEPATOLOGY 2010; 52: 1322-1333.
-
(2010)
HEPATOLOGY
, vol.52
, pp. 1322-1333
-
-
Yu, L.X.1
Yan, H.X.2
Liu, Q.3
Yang, W.4
Wu, H.P.5
Dong, W.6
-
10
-
-
4143103526
-
Lipopolysaccharides induced increases in fas ligand expression by kupffer cells via mechanisms dependent on reactive oxygen species
-
Uchikura K, Wada T, Hoshino S, Nagakawa Y, Aiko T, Bulkley GB, et al. Lipopolysaccharides induced increases in fas ligand expression by kupffer cells via mechanisms dependent on reactive oxygen species. Am J Physiol Gastrointest Liver Physiol 2004; 287: G620-G626.
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Uchikura, K.1
Wada, T.2
Hoshino, S.3
Nagakawa, Y.4
Aiko, T.5
Bulkley, G.B.6
-
11
-
-
77955982799
-
CYP2E1 potentiation of LPS and TNFalpha-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction
-
Lu Y, Cederbaum AI. CYP2E1 potentiation of LPS and TNFalpha-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction. Genes Nutr 2010; 5: 149-167.
-
(2010)
Genes Nutr
, vol.5
, pp. 149-167
-
-
Lu, Y.1
Cederbaum, A.I.2
-
12
-
-
77950825001
-
Alcoholic liver disease and the gut-liver axis
-
Szabo G, Bala S. Alcoholic liver disease and the gut-liver axis. World J Gastroenterol 2010; 16: 1321-1329.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 1321-1329
-
-
Szabo, G.1
Bala, S.2
-
13
-
-
34848914069
-
Signaling mechanisms in alcoholic liver injury: role of transcription factors, kinases, and heat shock proteins
-
Mandrekar P. Signaling mechanisms in alcoholic liver injury: role of transcription factors, kinases, and heat shock proteins. World J Gastroenterol 2007; 13: 4979-4985.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 4979-4985
-
-
Mandrekar, P.1
-
14
-
-
4344697308
-
Heat-shock protein 70 and heat-shock protein 90 associate with toll-like receptor 4 in response to bacterial lipopolysaccharide
-
Triantafilou M, Triantafilou K. Heat-shock protein 70 and heat-shock protein 90 associate with toll-like receptor 4 in response to bacterial lipopolysaccharide. Biochem Soc Trans 2004; 32: 636-639.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 636-639
-
-
Triantafilou, M.1
Triantafilou, K.2
-
15
-
-
33845876330
-
Geldanamycin interferes with the 90-kDa heat shock protein, affecting lipopolysaccharide-mediated interleukin-1 expression and apoptosis within macrophages
-
Hsu HY, Wu HL, Tan SK, Li VP, Wang WT, Hsu J, Cheng CH. Geldanamycin interferes with the 90-kDa heat shock protein, affecting lipopolysaccharide-mediated interleukin-1 expression and apoptosis within macrophages. Mol Pharmacol 2007; 71: 344-356.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 344-356
-
-
Hsu, H.Y.1
Wu, H.L.2
Tan, S.K.3
Li, V.P.4
Wang, W.T.5
Hsu, J.6
Cheng, C.H.7
-
16
-
-
0034928401
-
Fluorescence recovery after photobleaching reveals that LPS rapidly transfers from CD14 to hsp70 and hsp90 on the cell membrane
-
Triantafilou K, Triantafilou M, Ladha S, Mackie A, Dedrick RL, Fernandez N, Cherry R. Fluorescence recovery after photobleaching reveals that LPS rapidly transfers from CD14 to hsp70 and hsp90 on the cell membrane. J Cell Sci 2001; 114: 2535-2545.
-
(2001)
J Cell Sci
, vol.114
, pp. 2535-2545
-
-
Triantafilou, K.1
Triantafilou, M.2
Ladha, S.3
Mackie, A.4
Dedrick, R.L.5
Fernandez, N.6
Cherry, R.7
-
17
-
-
55549115036
-
Alcohol exposure regulates heat shock transcription factor binding and heat shock proteins 70 and 90 in monocytes and macrophages: implication for TNF-alpha regulation
-
Mandrekar P, Catalano D, Jeliazkova V, Kodys K. Alcohol exposure regulates heat shock transcription factor binding and heat shock proteins 70 and 90 in monocytes and macrophages: implication for TNF-alpha regulation. J Leukoc Biol 2008; 84: 1335-1345.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 1335-1345
-
-
Mandrekar, P.1
Catalano, D.2
Jeliazkova, V.3
Kodys, K.4
-
18
-
-
34347380341
-
Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis
-
Poulaki V, Iliaki E, Mitsiades N, Mitsiades CS, Paulus YN, Bula DV, et al. Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis. FASEB J 2007; 21: 2113-2123.
-
(2007)
FASEB J
, vol.21
, pp. 2113-2123
-
-
Poulaki, V.1
Iliaki, E.2
Mitsiades, N.3
Mitsiades, C.S.4
Paulus, Y.N.5
Bula, D.V.6
-
19
-
-
40649123232
-
Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90
-
Salminen A, Paimela T, Suuronen T, Kaarniranta K. Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90. Immunol Lett 2008; 117: 9-15.
-
(2008)
Immunol Lett
, vol.117
, pp. 9-15
-
-
Salminen, A.1
Paimela, T.2
Suuronen, T.3
Kaarniranta, K.4
-
20
-
-
77953446392
-
Dual role of heat shock proteins as regulators of apoptosis and innate immunity
-
Joly AL, Wettstein G, Mignot G, Ghiringhelli F, Garrido C. Dual role of heat shock proteins as regulators of apoptosis and innate immunity. J Innate Immun 2010; 2: 238-247.
-
(2010)
J Innate Immun
, vol.2
, pp. 238-247
-
-
Joly, A.L.1
Wettstein, G.2
Mignot, G.3
Ghiringhelli, F.4
Garrido, C.5
-
21
-
-
3142719113
-
Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation
-
Broemer M, Krappmann D, Scheidereit C. Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation. Oncogene 2004; 23: 5378-5386.
-
(2004)
Oncogene
, vol.23
, pp. 5378-5386
-
-
Broemer, M.1
Krappmann, D.2
Scheidereit, C.3
-
22
-
-
15444381172
-
A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors
-
De Nardo D, Masendycz P, Ho S, Cross M, Fleetwood AJ, Reynolds EC, et al. A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors. J Biol Chem 2005; 280: 9813-9822.
-
(2005)
J Biol Chem
, vol.280
, pp. 9813-9822
-
-
De Nardo, D.1
Masendycz, P.2
Ho, S.3
Cross, M.4
Fleetwood, A.J.5
Reynolds, E.C.6
-
23
-
-
77957667140
-
A human MAP kinase interactome
-
Bandyopadhyay S, Chiang CY, Srivastava J, Gersten M, White S, Bell R, et al. A human MAP kinase interactome. Nat Methods 2010; 7: 801-805.
-
(2010)
Nat Methods
, vol.7
, pp. 801-805
-
-
Bandyopadhyay, S.1
Chiang, C.Y.2
Srivastava, J.3
Gersten, M.4
White, S.5
Bell, R.6
-
24
-
-
79952734485
-
A phase I study of the heat shock protein 90 inhibitor alvespimycin (17-DMAG) given intravenously to patients with advanced solid tumors
-
Pacey S, Wilson RH, Walton M, Eatock MM, Hardcastle A, Zetterlund A, et al. A phase I study of the heat shock protein 90 inhibitor alvespimycin (17-DMAG) given intravenously to patients with advanced solid tumors. Clin Cancer Res 2011; 17: 1561-1570.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1561-1570
-
-
Pacey, S.1
Wilson, R.H.2
Walton, M.3
Eatock, M.M.4
Hardcastle, A.5
Zetterlund, A.6
-
25
-
-
78851472038
-
Inhibition of heat shock protein 90 (HSP90) as a therapeutic strategy for the treatment of myeloma and other cancers
-
Richardson PG, Mitsiades CS, Laubach JP, Lonial S, Chanan-Khan AA, Anderson KC. Inhibition of heat shock protein 90 (HSP90) as a therapeutic strategy for the treatment of myeloma and other cancers. Br J Haematol 2011; 152: 367-379.
-
(2011)
Br J Haematol
, vol.152
, pp. 367-379
-
-
Richardson, P.G.1
Mitsiades, C.S.2
Laubach, J.P.3
Lonial, S.4
Chanan-Khan, A.A.5
Anderson, K.C.6
-
26
-
-
78751566695
-
Heat-shock protein expression in leukemia
-
Sedlackova L, Spacek M, Holler E, Imryskova Z, Hromadnikova I. Heat-shock protein expression in leukemia. Tumour Biol 2011; 32: 33-44.
-
(2011)
Tumour Biol
, vol.32
, pp. 33-44
-
-
Sedlackova, L.1
Spacek, M.2
Holler, E.3
Imryskova, Z.4
Hromadnikova, I.5
-
27
-
-
78651423838
-
Novel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors
-
Allegra A, Sant'antonio E, Penna G, Alonci A, D'Angelo A, Russo S, et al. Novel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors. Eur J Haematol 2011; 86: 93-110.
-
(2011)
Eur J Haematol
, vol.86
, pp. 93-110
-
-
Allegra, A.1
Sant'antonio, E.2
Penna, G.3
Alonci, A.4
D'Angelo, A.5
Russo, S.6
-
28
-
-
57349131655
-
Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis
-
Rice JW, Veal JM, Fadden RP, Barabasz AF, Partridge JM, Barta TE, et al. Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis. Arthritis Rheum 2008; 58: 3765-3775.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3765-3775
-
-
Rice, J.W.1
Veal, J.M.2
Fadden, R.P.3
Barabasz, A.F.4
Partridge, J.M.5
Barta, T.E.6
-
29
-
-
74549211528
-
Modulation of Hsf1 activity by novobiocin and geldanamycin
-
Conde R, Belak ZR, Nair M, O'Carroll RF, Ovsenek N. Modulation of Hsf1 activity by novobiocin and geldanamycin. Biochem Cell Biol 2009; 87: 845-851.
-
(2009)
Biochem Cell Biol
, vol.87
, pp. 845-851
-
-
Conde, R.1
Belak, Z.R.2
Nair, M.3
O'Carroll, R.F.4
Ovsenek, N.5
-
30
-
-
0032701913
-
Geldanamycin induces heat shock protein expression through activation of HSF1 in K562 erythroleukemic cells
-
Kim HR, Kang HS, Kim HD. Geldanamycin induces heat shock protein expression through activation of HSF1 in K562 erythroleukemic cells. IUBMB Life 1999; 48: 429-433.
-
(1999)
IUBMB Life
, vol.48
, pp. 429-433
-
-
Kim, H.R.1
Kang, H.S.2
Kim, H.D.3
-
31
-
-
0032959590
-
Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin
-
Roe SM, Prodromou C, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin. J Med Chem 1999; 42: 260-266.
-
(1999)
J Med Chem
, vol.42
, pp. 260-266
-
-
Roe, S.M.1
Prodromou, C.2
O'Brien, R.3
Ladbury, J.E.4
Piper, P.W.5
Pearl, L.H.6
-
32
-
-
0030747256
-
Major stress protein Hsp70 interacts with NF-kB regulatory complex in human T-lymphoma cells
-
Guzhova IV, Darieva ZA, Melo AR, Margulis BA. Major stress protein Hsp70 interacts with NF-kB regulatory complex in human T-lymphoma cells. Cell Stress Chaperones 1997; 2: 132-139.
-
(1997)
Cell Stress Chaperones
, vol.2
, pp. 132-139
-
-
Guzhova, I.V.1
Darieva, Z.A.2
Melo, A.R.3
Margulis, B.A.4
-
33
-
-
3042855318
-
Bacterial endotoxin modifies heat shock factor-1 activity in RAW 264.7 cells: implications for TNF-alpha regulation during exposure to febrile range temperatures
-
Singh IS, He JR, Hester L, Fenton MJ, Hasday JD. Bacterial endotoxin modifies heat shock factor-1 activity in RAW 264.7 cells: implications for TNF-alpha regulation during exposure to febrile range temperatures. J Endotoxin Res 2004; 10: 175-184.
-
(2004)
J Endotoxin Res
, vol.10
, pp. 175-184
-
-
Singh, I.S.1
He, J.R.2
Hester, L.3
Fenton, M.J.4
Hasday, J.D.5
-
34
-
-
36349036470
-
Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor
-
Inouye S, Fujimoto M, Nakamura T, Takaki E, Hayashida N, Hai T, Nakai A. Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor. J Biol Chem 2007; 282: 33210-33217.
-
(2007)
J Biol Chem
, vol.282
, pp. 33210-33217
-
-
Inouye, S.1
Fujimoto, M.2
Nakamura, T.3
Takaki, E.4
Hayashida, N.5
Hai, T.6
Nakai, A.7
-
35
-
-
66149118221
-
HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic bcl-2 proteins
-
Jacobs AT, Marnett LJ. HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic bcl-2 proteins. J Biol Chem 2009; 284: 9176-9183.
-
(2009)
J Biol Chem
, vol.284
, pp. 9176-9183
-
-
Jacobs, A.T.1
Marnett, L.J.2
-
36
-
-
0034737461
-
Inhibition of tumor necrosis factor-alpha transcription in macrophages exposed to febrile range temperature. A possible role for heat shock factor-1 as a negative transcriptional regulator
-
Singh IS, Viscardi RM, Kalvakolanu I, Calderwood S, Hasday JD. Inhibition of tumor necrosis factor-alpha transcription in macrophages exposed to febrile range temperature. A possible role for heat shock factor-1 as a negative transcriptional regulator. J Biol Chem 2000; 275: 9841-9848.
-
(2000)
J Biol Chem
, vol.275
, pp. 9841-9848
-
-
Singh, I.S.1
Viscardi, R.M.2
Kalvakolanu, I.3
Calderwood, S.4
Hasday, J.D.5
-
37
-
-
76249095293
-
Heat shock transcription factor 1 inhibits expression of IL-6 through activating transcription factor 3
-
Takii R, Inouye S, Fujimoto M, Nakamura T, Shinkawa T, Prakasam R, et al. Heat shock transcription factor 1 inhibits expression of IL-6 through activating transcription factor 3. J Immunol 2010; 184: 1041-1048.
-
(2010)
J Immunol
, vol.184
, pp. 1041-1048
-
-
Takii, R.1
Inouye, S.2
Fujimoto, M.3
Nakamura, T.4
Shinkawa, T.5
Prakasam, R.6
-
38
-
-
0036091221
-
17-allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts
-
Solit DB, Zheng FF, Drobnjak M, Munster PN, Higgins B, Verbel D, et al. 17-allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts. Clin Cancer Res 2002; 8: 986-993.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 986-993
-
-
Solit, D.B.1
Zheng, F.F.2
Drobnjak, M.3
Munster, P.N.4
Higgins, B.5
Verbel, D.6
-
39
-
-
21244462689
-
In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative
-
Hollingshead M, Alley M, Burger AM, Borgel S, Pacula-Cox C, Fiebig HH, Sausville EA. In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative. Cancer Chemother Pharmacol 2005; 56: 115-125.
-
(2005)
Cancer Chemother Pharmacol
, vol.56
, pp. 115-125
-
-
Hollingshead, M.1
Alley, M.2
Burger, A.M.3
Borgel, S.4
Pacula-Cox, C.5
Fiebig, H.H.6
Sausville, E.A.7
-
40
-
-
0036139023
-
Pharmacokinetics, tissue distribution, and metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (NSC 707545) in CD2F1 mice and fischer 344 rats
-
Egorin MJ, Lagattuta TF, Hamburger DR, Covey JM, White KD, Musser SM, Eiseman JL. Pharmacokinetics, tissue distribution, and metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (NSC 707545) in CD2F1 mice and fischer 344 rats. Cancer Chemother Pharmacol 2002; 49: 7-19.
-
(2002)
Cancer Chemother Pharmacol
, vol.49
, pp. 7-19
-
-
Egorin, M.J.1
Lagattuta, T.F.2
Hamburger, D.R.3
Covey, J.M.4
White, K.D.5
Musser, S.M.6
Eiseman, J.L.7
-
41
-
-
67651160909
-
Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma
-
Breinig M, Caldas-Lopes E, Goeppert B, Malz M, Rieker R, Bergmann F, et al. Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma. HEPATOLOGY 2009; 50: 102-112.
-
(2009)
HEPATOLOGY
, vol.50
, pp. 102-112
-
-
Breinig, M.1
Caldas-Lopes, E.2
Goeppert, B.3
Malz, M.4
Rieker, R.5
Bergmann, F.6
-
42
-
-
79251588744
-
EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity
-
Yun TJ, Harning EK, Giza K, Rabah D, Li P, Arndt JW, et al. EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity. J Immunol 2011; 186: 563-575.
-
(2011)
J Immunol
, vol.186
, pp. 563-575
-
-
Yun, T.J.1
Harning, E.K.2
Giza, K.3
Rabah, D.4
Li, P.5
Arndt, J.W.6
-
43
-
-
34848829167
-
Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis
-
Chatterjee A, Dimitropoulou C, Drakopanayiotakis F, Antonova G, Snead C, Cannon J, et al. Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis. Am J Respir Crit Care Med 2007; 176: 667-675.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 667-675
-
-
Chatterjee, A.1
Dimitropoulou, C.2
Drakopanayiotakis, F.3
Antonova, G.4
Snead, C.5
Cannon, J.6
-
44
-
-
77951680995
-
Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis
-
Madrigal-Matute J, Lopez-Franco O, Blanco-Colio LM, Munoz-Garcia B, Ramos-Mozo P, Ortega L, et al. Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis. Cardiovasc Res 2010; 86: 330-337.
-
(2010)
Cardiovasc Res
, vol.86
, pp. 330-337
-
-
Madrigal-Matute, J.1
Lopez-Franco, O.2
Blanco-Colio, L.M.3
Munoz-Garcia, B.4
Ramos-Mozo, P.5
Ortega, L.6
-
45
-
-
0035834823
-
Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins
-
Brouet A, Sonveaux P, Dessy C, Moniotte S, Balligand JL, Feron O. Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins. Circ Res 2001; 89: 866-873.
-
(2001)
Circ Res
, vol.89
, pp. 866-873
-
-
Brouet, A.1
Sonveaux, P.2
Dessy, C.3
Moniotte, S.4
Balligand, J.L.5
Feron, O.6
-
46
-
-
0033890818
-
Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents
-
Bagatell R, Paine-Murrieta GD, Taylor CW, Pulcini EJ, Akinaga S, Benjamin IJ, Whitesell L. Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents. Clin Cancer Res 2000; 6: 3312-3318.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3312-3318
-
-
Bagatell, R.1
Paine-Murrieta, G.D.2
Taylor, C.W.3
Pulcini, E.J.4
Akinaga, S.5
Benjamin, I.J.6
Whitesell, L.7
-
47
-
-
0034921488
-
Geldanamycin inhibits NF-kappaB activation and interleukin-8 gene expression in cultured human respiratory epithelium
-
Malhotra V, Shanley TP, Pittet JF, Welch WJ, Wong HR. Geldanamycin inhibits NF-kappaB activation and interleukin-8 gene expression in cultured human respiratory epithelium. Am J Respir Cell Mol Biol 2001; 25: 92-97.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 92-97
-
-
Malhotra, V.1
Shanley, T.P.2
Pittet, J.F.3
Welch, W.J.4
Wong, H.R.5
-
48
-
-
0037329236
-
Geldanamycin treatment ameliorates the response to LPS in murine macrophages by decreasing CD14 surface expression
-
Vega VL, De Maio A. Geldanamycin treatment ameliorates the response to LPS in murine macrophages by decreasing CD14 surface expression. Mol Biol Cell 2003; 14: 764-773.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 764-773
-
-
Vega, V.L.1
De Maio, A.2
-
49
-
-
48649092274
-
Heat shock co-activates interleukin-8 transcription
-
Singh IS, Gupta A, Nagarsekar A, Cooper Z, Manka C, Hester L, et al. Heat shock co-activates interleukin-8 transcription. Am J Respir Cell Mol Biol 2008; 39: 235-242.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 235-242
-
-
Singh, I.S.1
Gupta, A.2
Nagarsekar, A.3
Cooper, Z.4
Manka, C.5
Hester, L.6
-
50
-
-
0037023695
-
Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6
-
Xie Y, Chen C, Stevenson MA, Auron PE, Calderwood SK. Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6. J Biol Chem 2002; 277: 11802-11810.
-
(2002)
J Biol Chem
, vol.277
, pp. 11802-11810
-
-
Xie, Y.1
Chen, C.2
Stevenson, M.A.3
Auron, P.E.4
Calderwood, S.K.5
-
51
-
-
77955717716
-
Febrile range temperature represses TNF-alpha gene expression in LPS-stimulated macrophages by selectively blocking recruitment of Sp1 to the TNF-alpha promoter
-
Cooper ZA, Singh IS, Hasday JD. Febrile range temperature represses TNF-alpha gene expression in LPS-stimulated macrophages by selectively blocking recruitment of Sp1 to the TNF-alpha promoter. Cell Stress Chaperones 2010; 15: 665-673.
-
(2010)
Cell Stress Chaperones
, vol.15
, pp. 665-673
-
-
Cooper, Z.A.1
Singh, I.S.2
Hasday, J.D.3
-
52
-
-
0033229880
-
HSF1 is required for extra-embryonic development, postnatal growth, and protection during inflammatory responses in mice
-
Xiao X, Zuo X, Davis AA, McMillan DR, Curry BB, Richardson JA, Benjamin IJ. HSF1 is required for extra-embryonic development, postnatal growth, and protection during inflammatory responses in mice. EMBO J 1999; 18: 5943-5952.
-
(1999)
EMBO J
, vol.18
, pp. 5943-5952
-
-
Xiao, X.1
Zuo, X.2
Davis, A.A.3
McMillan, D.R.4
Curry, B.B.5
Richardson, J.A.6
Benjamin, I.J.7
-
53
-
-
73549123428
-
Febrile-range temperature modifies cytokine gene expression in LPS-stimulated macrophages by differentially modifying NF-{kappa}B recruitment to cytokine gene promoters
-
Cooper ZA, Ghosh A, Gupta A, Maity T, Benjamin IJ, Vogel SN, et al. Febrile-range temperature modifies cytokine gene expression in LPS-stimulated macrophages by differentially modifying NF-{kappa}B recruitment to cytokine gene promoters. Am J Physiol Cell Physiol 2010; 298: C171-C181.
-
(2010)
Am J Physiol Cell Physiol
, vol.298
-
-
Cooper, Z.A.1
Ghosh, A.2
Gupta, A.3
Maity, T.4
Benjamin, I.J.5
Vogel, S.N.6
-
54
-
-
33846169368
-
Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice
-
Nakagawa S, Umehara T, Matsuda C, Kuge S, Sudoh M, Kohara M. Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice. Biochem Biophys Res Commun 2007; 353: 882-888.
-
(2007)
Biochem Biophys Res Commun
, vol.353
, pp. 882-888
-
-
Nakagawa, S.1
Umehara, T.2
Matsuda, C.3
Kuge, S.4
Sudoh, M.5
Kohara, M.6
-
55
-
-
65449118855
-
Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3
-
Ujino S, Yamaguchi S, Shimotohno K, Takaku H. Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3. J Biol Chem 2009; 284: 6841-6846.
-
(2009)
J Biol Chem
, vol.284
, pp. 6841-6846
-
-
Ujino, S.1
Yamaguchi, S.2
Shimotohno, K.3
Takaku, H.4
-
56
-
-
0037085476
-
A high affinity HSF-1 binding site in the 5′-untranslated region of the murine tumor necrosis factor-alpha gene is a transcriptional repressor
-
Singh IS, He JR, Calderwood S, Hasday JD. A high affinity HSF-1 binding site in the 5′-untranslated region of the murine tumor necrosis factor-alpha gene is a transcriptional repressor. J Biol Chem 2002; 277: 4981-4988.
-
(2002)
J Biol Chem
, vol.277
, pp. 4981-4988
-
-
Singh, I.S.1
He, J.R.2
Calderwood, S.3
Hasday, J.D.4
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