Late Na + current and protracted electrical recovery are critical determinants of the aging myopathy

Nature Communications

Volumn 6, Issue , 2015, Pages

  Signore, Sergio ^a   Sorrentino, Andrea ^a   Borghetti, Giulia ^a   Cannata, Antonio ^a   Meo, Marianna ^a   Zhou, Yu ^a   Kannappan, Ramaswamy ^a   Pasqualini, Francesco ^a   O'Malley, Heather ^b   Sundman, Mark ^a   Tsigkas, Nikolaos ^a   Zhang, Eric ^a   Arranto, Christian ^a   Mangiaracina, Chiara ^a   Isobe, Kazuya ^a   Sena, Brena F ^c   Kim, Junghyun ^a   Goichberg, Polina ^a   Nahrendorf, Matthias ^c   Isom, Lori L ^b   Leri, Annarosa ^a   Anversa, Piero ^a   Rota, Marcello ^a   more..

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM ION; CALCIUM; COLLAGEN; SCN1B PROTEIN, MOUSE; SODIUM; VOLTAGE GATED SODIUM CHANNEL BETA 1 SUBUNIT;

AGING; CALCIUM; CARDIOLOGY; COLLAGEN; ETIOLOGY; INHIBITION; RODENT; SODIUM;

ACTION POTENTIAL; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; FEMALE; HEART FUNCTION; HEART MUSCLE; HEART MUSCLE CELL; HEART PERFORMANCE; HEART VENTRICLE COMPLIANCE; ION CURRENT; MALE; MOUSE; MYOPATHY; NONHUMAN; REPOLARIZATION; SODIUM CURRENT; ANIMAL; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CARDIOMYOPATHY; DISEASE MODEL; GENETICS; HEART; HEART CONTRACTION; HEART VENTRICLE; KNOCKOUT MOUSE; METABOLISM; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY; SARCOPLASMIC RETICULUM;

ACTION POTENTIALS; AGING; ANIMALS; CALCIUM; CARDIOMYOPATHIES; COLLAGEN; DISEASE MODELS, ANIMAL; HEART; HEART VENTRICLES; MICE; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; SARCOPLASMIC RETICULUM; SODIUM; VOLTAGE-GATED SODIUM CHANNEL BETA-1 SUBUNIT;

EID: 84946599747     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9803     Document Type: Article

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