Alterations in action potential profile enhance excitation-contraction coupling in rat cardiac myocytes

Journal of Physiology

Volumn 533, Issue 1, 2001, Pages 201-214

  Sah, Rajan ^a   Ramirez, Rafael J ^a   Kaprielian, Roger ^a   Backx, Peter H ^a  

^a TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM;

ACTION POTENTIAL DURATION; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; CALCIUM CELL LEVEL; CELL SIZE; CELL STIMULATION; HEART VENTRICLE; MALE; STEADY STATE;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; HEART VENTRICLES; MALE; MUSCLE FIBERS; MYOCARDIAL CONTRACTION; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SARCOPLASMIC RETICULUM;

EID: 0035866930     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.0201b.x     Document Type: Article

References (55)

1. Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium
2. 2+] in intact rat cardiac trabeculae
3. Processes that remove calcium from the cytoplasm during excitation-contraction coupling in intact rat heart cells
4. Alterations in calcium handling in cardiac hypertrophy and heart failure
5. Relaxation in rabbit and rat cardiac cells: Species-dependent differences in cellular mechanisms
6. Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes
7. Fura-2 calcium transients in frog skeletal muscle fibres
8. Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure
9. + currents in isolated human ventricular myocytes from patients with terminal heart failure
10. Effects of action potential duration on excitation-contraction coupling in rat ventricular myocytes. Action potential voltage-clamp measurements
11. Investigation of the mechanisms underlying the increased contraction of hypertrophied ventricular myocytes isolated from the spontaneously hypertensive rat
12. Ionic basis of action potential prolongation of hypertrophied cardiac myocytes isolated from hypertensive rats of different ages
13. 2+ release sites in rat cardiac myocytes
14. 2+ release events in rat ventricular myocytes
15. Can NCX rapidly set the gain of EC coupling without directly triggering SR Ca release in the heart?
16. Reduction of calcium-independent transient outward potassium current density in DOCA salt hypertrophied rat ventricular myocytes
17. Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell
18. Role of cAMP-dependent protein kinase A in activation of a voltage-sensitive release mechanism for cardiac contraction in guinea-pig myocytes
19. + current modulates repolarization and excitation-contraction coupling in adult mouse ventricle
20. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure
21. Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure
22. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
23. 2+ release
24. Contribution of a voltage-sensitive calcium release mechanism to contraction in cardiac ventricular myocytes
25. 2+ release by voltage-clamp pulse duration in potentiated guinea-pig ventricular myocytes
26. 2+ current in cardiac cells
27. Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure
28. i in rat ventricular myocytes following myocardial infarction
29. 2+ exchange in excitation-contraction coupling in the heart
30. The effect of internal sodium and caesium on phasic contraction of patch-clamped rabbit ventricular myocytes
31. 2+ exchange in the infarcted heart. Implications for excitation-contraction coupling
32. Na-Ca exchange and the trigger for sarcoplasmic reticulum Ca release: Studies in adult rabbit ventricular myocytes
33. Local calcium transients triggered by single L-type calcium channel currents in cardiac cells
34. Regional differences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle
35. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: Experimental studies
36. Quantitative ultrastructural analysis in cardiac membrane physiology
37. 2+ current
38. Depressed transient outward current in single hypertrophied cardiomyocytes isolated from the right ventricle of ferret heart
39. 2+ channels in guinea-pig heart cells
40. 2+ sparks and local control theories for cardiac excitation-contraction coupling
41. Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes
42. 2+ release by a local inactivation of ryanodine receptors in cardiac myocytes
43. Cellular mechanisms of altered contractility in the hypertrophied heart: Big hearts, big sparks
44. 2+ exchange
45. 2+ across the sarcoplasmic reticulum of guinea-pig cardiac cells during excitation-contraction coupling
46. 2+ content during the cardiac cycle in guinea pig and rat ventricular myocytes
47. The effects of changes to action potential duration on the calcium content of the sarcoplasmic reticulum in isolated guinea-pig ventricular myocytes
48. 2+ content after depletion
49. An estimate of the calcium content of the sarcoplasmic reticulum in rat ventricular myocytes
50. 2+ exchange in activation of excitation-contraction coupling in rat ventricular myocytes
51. Transient outward current in human ventricular myocytes of subepicardial and subendocardial origin
52. The role of action potential prolongation and altered intracellular calcium handling in the pathogenesis of heart failure
53. + channel gene expression in rat ventricle
54. Local control of excitation-contraction coupling in rat heart cells