Autonomic blockade unmasks maturational differences in rate-dependent atrioventricular nodal conduction and facilitation in the mouse

Journal of Cardiovascular Electrophysiology

Volumn 14, Issue 2, 2003, Pages 191-195

  Saba, Samir ^a,b   London, Barry ^a   Ganz, Leonard ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Age; Atrioventricular nodal conduction; Autonomic blockade; Facilitation; Mouse

Indexed keywords

ADULTHOOD; AGE DISTRIBUTION; ANIMAL EXPERIMENT; ARTICLE; ATRIOVENTRICULAR BLOCK; ATRIOVENTRICULAR CONDUCTION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FACILITATION; FEMALE; HEART INNERVATION; IN VIVO STUDY; MATURATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REFRACTORY PERIOD; STATISTICAL SIGNIFICANCE;

EID: 0037307549     PISSN: 10453873     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1540-8167.2003.02454.x     Document Type: Article

References (16)

1. Amellal F, Hall K, Glass L, Billette J: Alternation of atrioventricular nodal conduction time during atrioventricular reentrant tachycardia: Are dual pathways necessary? J Cardiovasc Electrophysiol 1996;7:943-951.
2. Lewis T, Master AM: Observations upon conduction in the mammalian heart. AV conduction. Heart 1925;12:209-269.
3. Billette J, Nattel S: Dynamic behavior of the atrioventricular node: A functional model of interaction between recovery, facilitation, and fatigue. J Cardiovasc Electrophysiol 1994;5:90-102.
4. Nayebpour M, Talajic MC, Nattel S: Effects of beta-adrenergic receptor stimulation and blockade on rate-dependent atrioventricular nodal properties. Circ Res 1992;70:902-911.
5. Nayebpour M, Talajic M, Villemaire C, Nattel S: Vagal modulation of the rate-dependent properties of the atrioventricular node. Circ Res 1990;67:1152-1166.
6. Cheng Y, Mowrey K, Efimov I, Van Wagoner D, Tchou PJ, Mazgalev T: Effects of 2,3-butanedione monoxime on the atrial-atrioventricular nodal conduction in isolated rabbit heart. J Cardiovasc Electrophysiol 1997;8:790-802.
7. Billette J, Janse M, Van Capelle RH, Anderson RH, Touboul P, Durrer D: Cycle-length-dependent properties of AV nodal activation in rabbit hearts. Am J Physiol 1976;231:1129-1139.
8. Mazgalev T, Mowrey K, Efimov I, Fahy GJ, Van Wagoner D, Cheng Y, Tchou PJ: Mechanism of atrioventricular nodal facilitation in rabbit heart: Role of proximal AV node. Am J Physiol 1997;273:H1658-H1668.
9. Fahy GJ, Efimov I, Cheng Y, Kidwell GA, Van Wagoner D, Tchou PJ, Mazgalev T: Mechanism of atrioventricular nodal facilitation in rabbit heart: Role of the distal AV node. Am J Physiol 1997;272:H2815-H2825.
10. Taneja T, Mahnert BW, Passman R, Goldberger J, Kadish A: Effects of sex and age on electrocardiographic and cardiac electrophysiological properties in adults. Pacing Clin Electrophysiol 2001;24:16-21.
11. Maguire CT, Bevilacqua LM, Wakimoto H, Gehrmann J, Berul CI: Maturational atrioventricular nodal physiology in the mouse. J Cardiovasc Electrophysiol 2000;11:557-564.
12. Christensen G, Wang Y, Chien KR: Physiological assessment of complex cardiac phenotypes in genetically engineered mice. Am J Physiol 1997;41:H2513-H2524.
13. James JF, Hewett TE, Robbins J: Cardiac physiology in transgenic mice. Circ Res 1998;82:407-415.
14. Saba S, VanderBrink BA, Luciano B, Aronovitz MJ, Berul CI, Reddy S, Housman D, Mendelsohn ME, Estes NAM III, Wang PJ: Localization of the site of conduction abnormality in a mouse model of myotonic dystrophy. J Cardiovasc Electrophysiol 1999;10:1214-1220.
15. Saba S, Zhu W, Aronovitz MJ, Estes NAM, Wang PJ, Mendelsohn ME, Karas RH: Effects of estrogen on cardiac electrophysiology in female mice. J Cardiovasc Electrophysiol 2002;13:276-280.
16. Schmidlin O, Bharati S, Lev M, Schwartz JB: Effects of physiological aging on cardiac electrophysiology in perfused Fischer 344 rat hearts. Am J Physiol 1992;262:H97-H105.