-
1
-
-
80455144517
-
Insulin-like growth factor-binding protein-7 functions as a potential tumor suppressor in hepatocellular carcinoma
-
Chen D, Yoo BK, Santhekadur PK et al (2011) Insulin-like growth factor-binding protein-7 functions as a potential tumor suppressor in hepatocellular carcinoma. Clin Cancer Res 17, 6693-6701
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6693-6701
-
-
Chen, D.1
Yoo, B.K.2
Santhekadur, P.K.3
-
2
-
-
84856544687
-
PGC-1 family coactivators and cell fate: roles in cancer, neurodegeneration, cardiovascular disease and retrograde mitochondria-nucleus signalling
-
Jones AW, Yao Z, Vicencio JM, Karkucinska-Wieckowska A and Szabadkai G (2012) PGC-1 family coactivators and cell fate: roles in cancer, neurodegeneration, cardiovascular disease and retrograde mitochondria-nucleus signalling. Mitochondrion 12, 86-99
-
(2012)
Mitochondrion
, vol.12
, pp. 86-99
-
-
Jones, A.W.1
Yao, Z.2
Vicencio, J.M.3
Karkucinska-Wieckowska, A.4
Szabadkai, G.5
-
3
-
-
80053230881
-
Measurement of the inclusive jet cross section in pp collisions at radicals = 7 TeV
-
Chatrchyan S, Khachatryan V, Sirunyan AM et al (2011) Measurement of the inclusive jet cross section in pp collisions at radicals = 7 TeV. Phys Rev Lett 107, 132001
-
(2011)
Phys Rev Lett
, vol.107
, pp. 132001
-
-
Chatrchyan, S.1
Khachatryan, V.2
Sirunyan, A.M.3
-
4
-
-
84907367156
-
Protein molecular forms of insulin-like growth factor binding protein-2 change with aging
-
Sunderic M, Mihailovic N and Nedic O (2014) Protein molecular forms of insulin-like growth factor binding protein-2 change with aging. Exp Gerontol 58, 154-158
-
(2014)
Exp Gerontol
, vol.58
, pp. 154-158
-
-
Sunderic, M.1
Mihailovic, N.2
Nedic, O.3
-
5
-
-
0037007075
-
Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction
-
Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H and Komuro I (2002) Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation 105, 1541-1544
-
(2002)
Circulation
, vol.105
, pp. 1541-1544
-
-
Minamino, T.1
Miyauchi, H.2
Yoshida, T.3
Ishida, Y.4
Yoshida, H.5
Komuro, I.6
-
6
-
-
0027329926
-
The role of iron in senescence of dopaminergic neurons in Parkinson's disease
-
Youdim MB and Riederer P (1993) The role of iron in senescence of dopaminergic neurons in Parkinson's disease. J Neural Transm Suppl 40, 57-67
-
(1993)
J Neural Transm Suppl
, vol.40
, pp. 57-67
-
-
Youdim, M.B.1
Riederer, P.2
-
7
-
-
43749098300
-
Oxidative stress: from modification of cell-cycle related events, secondary messenger function, dysregulation of small GTPases, protein kinases and phosphatases to redox-sensitive cancer models
-
Hengstler JG and Bolt HM (2008) Oxidative stress: from modification of cell-cycle related events, secondary messenger function, dysregulation of small GTPases, protein kinases and phosphatases to redox-sensitive cancer models. Arch Toxicol 82, 271-272
-
(2008)
Arch Toxicol
, vol.82
, pp. 271-272
-
-
Hengstler, J.G.1
Bolt, H.M.2
-
8
-
-
82955205864
-
Interpretation and prediction of inhaled drug particle accumulation in the lung and its associated toxicity
-
Jones RM and Neef N (2012) Interpretation and prediction of inhaled drug particle accumulation in the lung and its associated toxicity. Xenobiotica 42, 86-93
-
(2012)
Xenobiotica
, vol.42
, pp. 86-93
-
-
Jones, R.M.1
Neef, N.2
-
9
-
-
84860803392
-
Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced beta5-integrin expression in human gastric cancer SC-M1 cells
-
Hung WY, Huang KH, Wu CW et al (2012) Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced beta5-integrin expression in human gastric cancer SC-M1 cells. Biochim Biophys Acta 1820, 1102-1110
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 1102-1110
-
-
Hung, W.Y.1
Huang, K.H.2
Wu, C.W.3
-
10
-
-
0037151065
-
The HMG-I/Y-related protein p8 binds to p300 and Pax2 transactivation domain-interacting protein to regulate the transactivation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter
-
Hoffmeister A, Ropolo A, Vasseur S et al (2002) The HMG-I/Y-related protein p8 binds to p300 and Pax2 transactivation domain-interacting protein to regulate the transactivation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter. J Biol Chem 277, 22314-22319
-
(2002)
J Biol Chem
, vol.277
, pp. 22314-22319
-
-
Hoffmeister, A.1
Ropolo, A.2
Vasseur, S.3
-
12
-
-
84871876622
-
Exploring minimally invasive options: managing demands, expectations, and outcomes
-
31, 86, 88, 90 passim
-
Engelberg B and Jones B (2012) Exploring minimally invasive options: managing demands, expectations, and outcomes. Dent Today 31, 86, 88, 90 passim
-
(2012)
Dent Today
-
-
Engelberg, B.1
Jones, B.2
-
13
-
-
0029962187
-
Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence
-
West MD, Shay JW, Wright WE and Linskens MH (1996) Altered expression of plasminogen activator and plasminogen activator inhibitor during cellular senescence. Exp Gerontol 31, 175-193
-
(1996)
Exp Gerontol
, vol.31
, pp. 175-193
-
-
West, M.D.1
Shay, J.W.2
Wright, W.E.3
Linskens, M.H.4
-
14
-
-
84869488061
-
Lessons from C. elegans: signaling pathways for longevity
-
Lapierre LR and Hansen M (2012) Lessons from C. elegans: signaling pathways for longevity. Trends Endocrinol Metab 23, 637-644
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 637-644
-
-
Lapierre, L.R.1
Hansen, M.2
-
15
-
-
0029089162
-
Senescencedependent regulation of type 1 plasminogen activator inhibitor in human vascular endothelial cells
-
Comi P, Chiaramonte R and Maier JA (1995) Senescencedependent regulation of type 1 plasminogen activator inhibitor in human vascular endothelial cells. Exp Cell Res 219, 304-308
-
(1995)
Exp Cell Res
, vol.219
, pp. 304-308
-
-
Comi, P.1
Chiaramonte, R.2
Maier, J.A.3
-
16
-
-
84908213474
-
Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?
-
Sabharwal SS and Schumacker PT (2014) Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel? Nat Rev Cancer 14, 709-721
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 709-721
-
-
Sabharwal, S.S.1
Schumacker, P.T.2
-
17
-
-
84873105931
-
Beyond retrograde and anterograde signalling: mitochondrial-nuclear interactions as a means for evolutionary adaptation and contemporary disease susceptibility
-
Ballinger SW (2013) Beyond retrograde and anterograde signalling: mitochondrial-nuclear interactions as a means for evolutionary adaptation and contemporary disease susceptibility. Biochem Soc Trans 41, 111-117
-
(2013)
Biochem Soc Trans
, vol.41
, pp. 111-117
-
-
Ballinger, S.W.1
-
18
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G et al (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A 92, 9363-9367
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
-
19
-
-
70549109118
-
The granulin gene family: from cancer to dementia
-
Bateman A and Bennett HP (2009) The granulin gene family: from cancer to dementia. Bioessays 31, 1245-1254
-
(2009)
Bioessays
, vol.31
, pp. 1245-1254
-
-
Bateman, A.1
Bennett, H.P.2
-
20
-
-
0033535365
-
Endogenous oxidative damage of mtDNA
-
Beckman KB and Ames BN (1999) Endogenous oxidative damage of mtDNA. Mutat Res 424, 51-58
-
(1999)
Mutat Res
, vol.424
, pp. 51-58
-
-
Beckman, K.B.1
Ames, B.N.2
-
21
-
-
0033081478
-
Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk
-
Biswas G, Adebanjo OA, Freedman BD et al (1999) Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk. EMBO J 18, 522-533
-
(1999)
EMBO J
, vol.18
, pp. 522-533
-
-
Biswas, G.1
Adebanjo, O.A.2
Freedman, B.D.3
-
22
-
-
0038612839
-
Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkappaB/Rel activation through calcineurin-mediated inactivation of IkappaBbeta
-
Biswas G, Anandatheerthavarada HK, Zaidi M and Avadhani NG (2003) Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkappaB/Rel activation through calcineurin-mediated inactivation of IkappaBbeta. J Cell Biol 161, 507-519
-
(2003)
J Cell Biol
, vol.161
, pp. 507-519
-
-
Biswas, G.1
Anandatheerthavarada, H.K.2
Zaidi, M.3
Avadhani, N.G.4
-
23
-
-
33750627938
-
'To repair or not to repair - no longer a question': repair of mitochondrial DNA shielding against age and cancer
-
Berneburg M, Kamenisch Y, Krutmann J and Rocken M (2006) 'To repair or not to repair - no longer a question': repair of mitochondrial DNA shielding against age and cancer. Exp Dermatol 15, 1005-1015
-
(2006)
Exp Dermatol
, vol.15
, pp. 1005-1015
-
-
Berneburg, M.1
Kamenisch, Y.2
Krutmann, J.3
Rocken, M.4
-
24
-
-
84876449244
-
Suppression of mitochondrial complex I influences cell metastatic properties
-
He X, Zhou A, Lu H et al (2013) Suppression of mitochondrial complex I influences cell metastatic properties. PLoS One 8, e61677
-
(2013)
PLoS One
, vol.8
-
-
He, X.1
Zhou, A.2
Lu, H.3
-
25
-
-
0034192265
-
The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis
-
Boiteux S and Radicella JP (2000) The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis. Arch Biochem Biophys 377, 1-8
-
(2000)
Arch Biochem Biophys
, vol.377
, pp. 1-8
-
-
Boiteux, S.1
Radicella, J.P.2
-
26
-
-
33746466098
-
Mitochondrial mutations in cancer
-
Brandon M, Baldi P and Wallace DC (2006) Mitochondrial mutations in cancer. Oncogene 25, 4647-4662
-
(2006)
Oncogene
, vol.25
, pp. 4647-4662
-
-
Brandon, M.1
Baldi, P.2
Wallace, D.C.3
-
27
-
-
45149099742
-
Expression and modification of ARC (apoptosis repressor with a CARD domain) is distinctly regulated by oxidative stress in cancer cells
-
Zhang YQ and Herman B (2008) Expression and modification of ARC (apoptosis repressor with a CARD domain) is distinctly regulated by oxidative stress in cancer cells. J Cell Biochem 104, 818-825
-
(2008)
J Cell Biochem
, vol.104
, pp. 818-825
-
-
Zhang, Y.Q.1
Herman, B.2
-
29
-
-
18244384703
-
Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress
-
Guettouche T, Boellmann F, Lane WS and Voellmy R (2005) Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress. BMC Biochem 6, 4
-
(2005)
BMC Biochem
, vol.6
, pp. 4
-
-
Guettouche, T.1
Boellmann, F.2
Lane, W.S.3
Voellmy, R.4
-
30
-
-
1842665662
-
Mitochondrial signaling: the retrograde response
-
Butow RA and Avadhani NG (2004) Mitochondrial signaling: the retrograde response. Mol Cell 14, 1-15
-
(2004)
Mol Cell
, vol.14
, pp. 1-15
-
-
Butow, R.A.1
Avadhani, N.G.2
-
31
-
-
84863785173
-
GSK3 inactivation is involved in mitochondrial complex IV defect in transforming growth factor (TGF) beta1-induced senescence
-
Byun HO, Jung HJ, Seo YH et al (2012) GSK3 inactivation is involved in mitochondrial complex IV defect in transforming growth factor (TGF) beta1-induced senescence. Exp Cell Res 318, 1808-1819
-
(2012)
Exp Cell Res
, vol.318
, pp. 1808-1819
-
-
Byun, H.O.1
Jung, H.J.2
Seo, Y.H.3
-
32
-
-
0037038669
-
Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
-
Amuthan G, Biswas G, Ananadatheerthavarada HK, Vijayasarathy C, Shephard HM and Avadhani NG (2002) Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene 21, 7839-7849
-
(2002)
Oncogene
, vol.21
, pp. 7839-7849
-
-
Amuthan, G.1
Biswas, G.2
Ananadatheerthavarada, H.K.3
Vijayasarathy, C.4
Shephard, H.M.5
Avadhani, N.G.6
-
33
-
-
49349105432
-
Mitochondrial dysfunction by complex II inhibition delays overall cell cycle progression via reactive oxygen species production
-
Byun HO, Kim HY, Lim JJ, Seo YH and Yoon G (2008) Mitochondrial dysfunction by complex II inhibition delays overall cell cycle progression via reactive oxygen species production. J Cell Biochem 104, 1747-1759
-
(2008)
J Cell Biochem
, vol.104
, pp. 1747-1759
-
-
Byun, H.O.1
Kim, H.Y.2
Lim, J.J.3
Seo, Y.H.4
Yoon, G.5
-
34
-
-
0035725834
-
Identification of genes in the oligodendrocyte lineage through the analysis of conditionally immortalized cell lines
-
Campagnoni CW, Landry CF, Pribyl TM et al (2001) Identification of genes in the oligodendrocyte lineage through the analysis of conditionally immortalized cell lines. Dev Neurosci 23, 452-463
-
(2001)
Dev Neurosci
, vol.23
, pp. 452-463
-
-
Campagnoni, C.W.1
Landry, C.F.2
Pribyl, T.M.3
-
36
-
-
2942531063
-
Mitochondrial defects in cancer
-
Carew JS and Huang P (2002) Mitochondrial defects in cancer. Mol Cancer 1, 9
-
(2002)
Mol Cancer
, vol.1
, pp. 9
-
-
Carew, J.S.1
Huang, P.2
-
37
-
-
84875199413
-
A systems approach for decoding mitochondrial retrograde signaling pathways
-
Chae S, Ahn BY, Byun K et al (2013) A systems approach for decoding mitochondrial retrograde signaling pathways. Sci Signal 6, rs4
-
(2013)
Sci Signal
, vol.6
, pp. rs4
-
-
Chae, S.1
Ahn, B.Y.2
Byun, K.3
-
38
-
-
67650665969
-
Mitochondrial dysfunction-induced amphiregulin upregulation mediates chemo-resistance and cell migration in HepG2 cells
-
Chang CJ, Yin PH, Yang DM et al (2009) Mitochondrial dysfunction-induced amphiregulin upregulation mediates chemo-resistance and cell migration in HepG2 cells. Cell Mol Life Sci 66, 1755-1765
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 1755-1765
-
-
Chang, C.J.1
Yin, P.H.2
Yang, D.M.3
-
39
-
-
33746891176
-
Mitochondrial DNA mutations in human cancer
-
Chatterjee A, Mambo E and Sidransky D (2006) Mitochondrial DNA mutations in human cancer. Oncogene 25, 4663-4674
-
(2006)
Oncogene
, vol.25
, pp. 4663-4674
-
-
Chatterjee, A.1
Mambo, E.2
Sidransky, D.3
-
40
-
-
0031754316
-
Molecular mechanisms for the senescent cell cycle arrest
-
Stein GH and Dulic V (1998) Molecular mechanisms for the senescent cell cycle arrest. J Investig Dermatol Symp Proc 3, 14-18
-
(1998)
J Investig Dermatol Symp Proc
, vol.3
, pp. 14-18
-
-
Stein, G.H.1
Dulic, V.2
-
41
-
-
67650828068
-
A comparative analysis of the cell biology of senescence and aging
-
Hwang ES, Yoon G and Kang HT (2009) A comparative analysis of the cell biology of senescence and aging. Cell Mol Life Sci 66, 2503-2524
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2503-2524
-
-
Hwang, E.S.1
Yoon, G.2
Kang, H.T.3
-
42
-
-
9344229795
-
Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma
-
Cheung ST, Wong SY, Leung KL et al (2004) Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma. Clin Cancer Res 10, 7629-7636
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7629-7636
-
-
Cheung, S.T.1
Wong, S.Y.2
Leung, K.L.3
-
44
-
-
0031920601
-
Nuclear-mitochondrial intergenomic communication
-
Clayton DA (1998) Nuclear-mitochondrial intergenomic communication. Biofactors 7, 203-205
-
(1998)
Biofactors
, vol.7
, pp. 203-205
-
-
Clayton, D.A.1
-
45
-
-
0029029471
-
Modelling the effects of age-related mtDNA mutation accumulation; complex I deficiency, superoxide and cell death
-
Cortopassi G and Wang E (1995) Modelling the effects of age-related mtDNA mutation accumulation; complex I deficiency, superoxide and cell death. Biochim Biophys Acta 1271, 171-176
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 171-176
-
-
Cortopassi, G.1
Wang, E.2
-
46
-
-
77956518736
-
Sterol regulatory element-binding protein (SREBP)-1-mediated lipogenesis is involved in cell senescence
-
Kim YM, Shin HT, Seo YH et al (2010) Sterol regulatory element-binding protein (SREBP)-1-mediated lipogenesis is involved in cell senescence. J Biol Chem 285, 29069-29077
-
(2010)
J Biol Chem
, vol.285
, pp. 29069-29077
-
-
Kim, Y.M.1
Shin, H.T.2
Seo, Y.H.3
-
47
-
-
79952770021
-
Measurement of the B(+) production cross section in pp collisions at sqrt[s] = 7 TeV
-
Khachatryan V, Sirunyan AM, Tumasyan A et al (2011) Measurement of the B(+) production cross section in pp collisions at sqrt[s] = 7 TeV. Phys Rev Lett 106, 112001
-
(2011)
Phys Rev Lett
, vol.106
, pp. 112001
-
-
Khachatryan, V.1
Sirunyan, A.M.2
Tumasyan, A.3
-
48
-
-
77951230124
-
Mitochondrial DNA mutations in cancer--from bench to bedside
-
Czarnecka AM, Kukwa W, Krawczyk T, Scinska A, Kukwa A and Cappello F (2010) Mitochondrial DNA mutations in cancer--from bench to bedside. Front Biosci 15, 437-460
-
(2010)
Front Biosci
, vol.15
, pp. 437-460
-
-
Czarnecka, A.M.1
Kukwa, W.2
Krawczyk, T.3
Scinska, A.4
Kukwa, A.5
Cappello, F.6
-
49
-
-
84893677011
-
PFKFB3 regulates oxidative stress homeostasis via its S-glutathionylation in cancer
-
Seo M and Lee YH (2014) PFKFB3 regulates oxidative stress homeostasis via its S-glutathionylation in cancer. J Mol Biol 426, 830-842
-
(2014)
J Mol Biol
, vol.426
, pp. 830-842
-
-
Seo, M.1
Lee, Y.H.2
-
50
-
-
0026793281
-
Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts
-
Millis AJ, Hoyle M, McCue HM and Martini H (1992) Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts. Exp Cell Res 201, 373-379
-
(1992)
Exp Cell Res
, vol.201
, pp. 373-379
-
-
Millis, A.J.1
Hoyle, M.2
McCue, H.M.3
Martini, H.4
-
51
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppe JP, Patil CK, Rodier F et al (2008) Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol 6, 2853-2868
-
(2008)
PLoS Biol
, vol.6
, pp. 2853-2868
-
-
Coppe, J.P.1
Patil, C.K.2
Rodier, F.3
-
52
-
-
0037308463
-
Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy
-
Imamura H, Matsuyama Y, Tanaka E et al (2003) Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy. J Hepatol 38, 200-207
-
(2003)
J Hepatol
, vol.38
, pp. 200-207
-
-
Imamura, H.1
Matsuyama, Y.2
Tanaka, E.3
-
53
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F and Campisi J (2011) Four faces of cellular senescence. J Cell Biol 192, 547-556
-
(2011)
J Cell Biol
, vol.192
, pp. 547-556
-
-
Rodier, F.1
Campisi, J.2
-
54
-
-
84894212929
-
The senescence-associated secretory phenotype promotes benign prostatic hyperplasia
-
Vital P, Castro P, Tsang S and Ittmann M (2014) The senescence-associated secretory phenotype promotes benign prostatic hyperplasia. Am J Pathol 184, 721-731
-
(2014)
Am J Pathol
, vol.184
, pp. 721-731
-
-
Vital, P.1
Castro, P.2
Tsang, S.3
Ittmann, M.4
-
55
-
-
84924185866
-
Interleukin-10 protects against atherosclerosis by modulating multiple atherogenic macrophage function
-
Han X and Boisvert WA (2015) Interleukin-10 protects against atherosclerosis by modulating multiple atherogenic macrophage function. Thromb Haemost 113, 505-512
-
(2015)
Thromb Haemost
, vol.113
, pp. 505-512
-
-
Han, X.1
Boisvert, W.A.2
-
56
-
-
79959484702
-
CPEB control of NF-kappaB nuclear localization and interleukin-6 production mediates cellular senescence
-
Groppo R and Richter JD (2011) CPEB control of NF-kappaB nuclear localization and interleukin-6 production mediates cellular senescence. Mol Cell Biol 31, 2707-2714
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2707-2714
-
-
Groppo, R.1
Richter, J.D.2
-
57
-
-
0028924516
-
Increased p53 protein associated with aging in human diploid fibroblasts
-
Kulju KS and Lehman JM (1995) Increased p53 protein associated with aging in human diploid fibroblasts. Exp Cell Res 217, 336-345
-
(1995)
Exp Cell Res
, vol.217
, pp. 336-345
-
-
Kulju, K.S.1
Lehman, J.M.2
-
58
-
-
77952509221
-
Glycolysis links p53 function with NF-kappaB signaling: impact on cancer and aging process
-
Salminen A and Kaarniranta K (2010) Glycolysis links p53 function with NF-kappaB signaling: impact on cancer and aging process. J Cell Physiol 224, 1-6
-
(2010)
J Cell Physiol
, vol.224
, pp. 1-6
-
-
Salminen, A.1
Kaarniranta, K.2
-
59
-
-
3242708498
-
Contribution of p16 (INK4a) to replicative senescence of human fibroblasts
-
Brookes S, Rowe J, Gutierrez Del Arroyo A, Bond J and Peters G (2004) Contribution of p16 (INK4a) to replicative senescence of human fibroblasts. Exp Cell Res 298, 549-559
-
(2004)
Exp Cell Res
, vol.298
, pp. 549-559
-
-
Brookes, S.1
Rowe, J.2
Gutierrez Del Arroyo, A.3
Bond, J.4
Peters, G.5
-
60
-
-
1442340729
-
Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells
-
Delsite R, Kachhap S, Anbazhagan R, Gabrielson E and Singh KK (2002) Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells. Mol Cancer 1, 6
-
(2002)
Mol Cancer
, vol.1
, pp. 6
-
-
Delsite, R.1
Kachhap, S.2
Anbazhagan, R.3
Gabrielson, E.4
Singh, K.K.5
-
61
-
-
84893853784
-
Progranulin: a novel regulator of gastrointestinal cancer progression
-
Demorrow S (2013) Progranulin: a novel regulator of gastrointestinal cancer progression. Transl Gastrointest Cancer 2, 145-151
-
(2013)
Transl Gastrointest Cancer
, vol.2
, pp. 145-151
-
-
Demorrow, S.1
-
62
-
-
77950298030
-
Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28
-
Di Bella D, Lazzaro F, Brusco A et al (2010) Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet 42, 313-321
-
(2010)
Nat Genet
, vol.42
, pp. 313-321
-
-
Di Bella, D.1
Lazzaro, F.2
Brusco, A.3
-
63
-
-
1542358848
-
Repair of oxidative damage in mitochondrial DNA of Saccharomyces cerevisiae: involvement of the MSH1-dependent pathway
-
Dzierzbicki P, Koprowski P, Fikus MU, Malc E and Ciesla Z (2004) Repair of oxidative damage in mitochondrial DNA of Saccharomyces cerevisiae: involvement of the MSH1-dependent pathway. DNA Repair (Amst) 3, 403-411
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 403-411
-
-
Dzierzbicki, P.1
Koprowski, P.2
Fikus, M.U.3
Malc, E.4
Ciesla, Z.5
-
64
-
-
0037972522
-
Mitochondrial respiratory-chain diseases
-
DiMauro S and Schon EA (2003) Mitochondrial respiratory-chain diseases. N Engl J Med 348, 2656-2668
-
(2003)
N Engl J Med
, vol.348
, pp. 2656-2668
-
-
DiMauro, S.1
Schon, E.A.2
-
65
-
-
0035951881
-
Human p8 is a HMG-I/Y-like protein with DNA binding activity enhanced by phosphorylation
-
Encinar JA, Mallo GV, Mizyrycki C et al (2001) Human p8 is a HMG-I/Y-like protein with DNA binding activity enhanced by phosphorylation. J Biol Chem 276, 2742-2751
-
(2001)
J Biol Chem
, vol.276
, pp. 2742-2751
-
-
Encinar, J.A.1
Mallo, G.V.2
Mizyrycki, C.3
-
66
-
-
66049087696
-
The coordination of nuclear and mitochondrial communication during aging and calorie restriction
-
Finley LW and Haigis MC (2009) The coordination of nuclear and mitochondrial communication during aging and calorie restriction. Ageing Res Rev 8, 173-188
-
(2009)
Ageing Res Rev
, vol.8
, pp. 173-188
-
-
Finley, L.W.1
Haigis, M.C.2
-
67
-
-
0032441094
-
Immunochemical detection of oxidative DNA damage in cancer and aging using anti-reactive oxygen species modified DNA monoclonal antibody
-
Ashok BT, Ahmad J and Ali R (1998) Immunochemical detection of oxidative DNA damage in cancer and aging using anti-reactive oxygen species modified DNA monoclonal antibody. Int J Biochem Cell Biol 30, 1367-1377
-
(1998)
Int J Biochem Cell Biol
, vol.30
, pp. 1367-1377
-
-
Ashok, B.T.1
Ahmad, J.2
Ali, R.3
-
68
-
-
0029010132
-
Human genome organization
-
Gardiner K (1995) Human genome organization. Curr Opin Genet Dev 5, 315-322
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 315-322
-
-
Gardiner, K.1
-
69
-
-
0037107396
-
Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy
-
Goruppi S, Bonventre JV and Kyriakis JM (2002) Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy. EMBO J 21, 5427-5436
-
(2002)
EMBO J
, vol.21
, pp. 5427-5436
-
-
Goruppi, S.1
Bonventre, J.V.2
Kyriakis, J.M.3
-
70
-
-
31544450585
-
p8 is a new target of gemcitabine in pancreatic cancer cells
-
Giroux V, Malicet C, Barthet M et al (2006) p8 is a new target of gemcitabine in pancreatic cancer cells. Clin Cancer Res 12, 235-241
-
(2006)
Clin Cancer Res
, vol.12
, pp. 235-241
-
-
Giroux, V.1
Malicet, C.2
Barthet, M.3
-
71
-
-
2442675146
-
The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypertrophy require NFAT4
-
Goruppi S and Kyriakis JM (2004) The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypertrophy require NFAT4. J Biol Chem 279, 20950-20958
-
(2004)
J Biol Chem
, vol.279
, pp. 20950-20958
-
-
Goruppi, S.1
Kyriakis, J.M.2
-
72
-
-
84867379842
-
Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems
-
Gredilla R, Garm C and Stevnsner T (2012) Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems. Oxid Med Cell Longev 2012, 282438
-
(2012)
Oxid Med Cell Longev
, vol.2012
, pp. 282438
-
-
Gredilla, R.1
Garm, C.2
Stevnsner, T.3
-
73
-
-
0027324378
-
Mutagenesis by 8-oxoguanine: an enemy within
-
Grollman AP and Moriya M (1993) Mutagenesis by 8-oxoguanine: an enemy within. Trends Genet 9, 246-249
-
(1993)
Trends Genet
, vol.9
, pp. 246-249
-
-
Grollman, A.P.1
Moriya, M.2
-
74
-
-
84884337715
-
Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics
-
Guha M and Avadhani NG (2013) Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics. Mitochondrion 13, 577-591
-
(2013)
Mitochondrion
, vol.13
, pp. 577-591
-
-
Guha, M.1
Avadhani, N.G.2
-
75
-
-
67649836371
-
Balloon-occluded retrograde transvenous obliteration for gastric varices in a child with extrahepatic portal venous obstruction
-
Takahashi T, Yoshida H, Mamada Y, Taniai N and Tajiri T (2009) Balloon-occluded retrograde transvenous obliteration for gastric varices in a child with extrahepatic portal venous obstruction. J Nippon Med Sch 76, 173-178
-
(2009)
J Nippon Med Sch
, vol.76
, pp. 173-178
-
-
Takahashi, T.1
Yoshida, H.2
Mamada, Y.3
Taniai, N.4
Tajiri, T.5
-
76
-
-
84861821128
-
Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis
-
Hamidi T, Algul H, Cano CE et al (2012) Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. J Clin Invest 122, 2092-2103
-
(2012)
J Clin Invest
, vol.122
, pp. 2092-2103
-
-
Hamidi, T.1
Algul, H.2
Cano, C.E.3
-
77
-
-
84866931110
-
Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death
-
Hamidi T, Cano CE, Grasso D et al (2012) Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death. Clin Cancer Res 18, 5234-5246
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5234-5246
-
-
Hamidi, T.1
Cano, C.E.2
Grasso, D.3
-
78
-
-
33750049931
-
Lack of mitochondrial DNA enhances growth of hepatocellular carcinoma in vitro and in vivo
-
Haque A, Nishikawa M, Qian W et al (2006) Lack of mitochondrial DNA enhances growth of hepatocellular carcinoma in vitro and in vivo. Hepatol Res 36, 209-216
-
(2006)
Hepatol Res
, vol.36
, pp. 209-216
-
-
Haque, A.1
Nishikawa, M.2
Qian, W.3
-
79
-
-
6944240044
-
The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity
-
Hashiguchi K, Stuart JA, de Souza-Pinto NC and Bohr VA (2004) The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity. Nucleic Acids Res 32, 5596-5608
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 5596-5608
-
-
Hashiguchi, K.1
Stuart, J.A.2
de Souza-Pinto, N.C.3
Bohr, V.A.4
-
80
-
-
0034615550
-
Tissue inhibitors of metalloproteinases: evolution, structure and function
-
Brew K, Dinakarpandian D and Nagase H (2000) Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim Biophys Acta 1477, 267-283
-
(2000)
Biochim Biophys Acta
, vol.1477
, pp. 267-283
-
-
Brew, K.1
Dinakarpandian, D.2
Nagase, H.3
-
81
-
-
1542407821
-
ACTH induces TIMP-1 expression and inhibits collagenase in adrenal cortex cells
-
Reichenstein M, Reich R, LeHoux JG and Hanukoglu I (2004) ACTH induces TIMP-1 expression and inhibits collagenase in adrenal cortex cells. Mol Cell Endocrinol 215, 109-114
-
(2004)
Mol Cell Endocrinol
, vol.215
, pp. 109-114
-
-
Reichenstein, M.1
Reich, R.2
LeHoux, J.G.3
Hanukoglu, I.4
-
82
-
-
0036544849
-
Plasminogen activator inhibitor 1: physiological and pathophysiological roles
-
Binder BR, Christ G, Gruber F et al (2002) Plasminogen activator inhibitor 1: physiological and pathophysiological roles. News Physiol Sci 17, 56-61
-
(2002)
News Physiol Sci
, vol.17
, pp. 56-61
-
-
Binder, B.R.1
Christ, G.2
Gruber, F.3
-
83
-
-
34248343425
-
Plasminogen activator inhibitor-1, adipose tissue and insulin resistance
-
Alessi MC, Poggi M and Juhan-Vague I (2007) Plasminogen activator inhibitor-1, adipose tissue and insulin resistance. Curr Opin Lipidol 18, 240-245
-
(2007)
Curr Opin Lipidol
, vol.18
, pp. 240-245
-
-
Alessi, M.C.1
Poggi, M.2
Juhan-Vague, I.3
-
84
-
-
1642318429
-
The structural basis for the pathophysiological relevance of PAI-I in cardiovascular diseases and the development of potential PAI-I inhibitors
-
Gils A and Declerck PJ (2004) The structural basis for the pathophysiological relevance of PAI-I in cardiovascular diseases and the development of potential PAI-I inhibitors. Thromb Haemost 91, 425-437
-
(2004)
Thromb Haemost
, vol.91
, pp. 425-437
-
-
Gils, A.1
Declerck, P.J.2
-
86
-
-
0033304507
-
The insulin-like growth factor-binding protein (IGFBP) superfamily
-
Hwa V, Oh Y and Rosenfeld RG (1999) The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr Rev 20, 761-787
-
(1999)
Endocr Rev
, vol.20
, pp. 761-787
-
-
Hwa, V.1
Oh, Y.2
Rosenfeld, R.G.3
-
87
-
-
0027171662
-
Potentiation of insulin-like growth factor-I (IGF-I) activity by an antibody: supportive evidence for enhancement of IGF-I bioavailability in vivo by IGF binding proteins
-
Stewart CE, Bates PC, Calder TA, Woodall SM and Pell JM (1993) Potentiation of insulin-like growth factor-I (IGF-I) activity by an antibody: supportive evidence for enhancement of IGF-I bioavailability in vivo by IGF binding proteins. Endocrinology 133, 1462-1465
-
(1993)
Endocrinology
, vol.133
, pp. 1462-1465
-
-
Stewart, C.E.1
Bates, P.C.2
Calder, T.A.3
Woodall, S.M.4
Pell, J.M.5
-
88
-
-
0029433537
-
Role of insulin-like growth factor binding proteins in the control of IGF actions
-
Clemmons DR, Busby WH, Arai T et al (1995) Role of insulin-like growth factor binding proteins in the control of IGF actions. Prog Growth Factor Res 6, 357-366
-
(1995)
Prog Growth Factor Res
, vol.6
, pp. 357-366
-
-
Clemmons, D.R.1
Busby, W.H.2
Arai, T.3
-
89
-
-
70350125106
-
Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
-
Orjalo AV, Bhaumik D, Gengler BK, Scott GK and Campisi J (2009) Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network. Proc Natl Acad Sci U S A 106, 17031-17036
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 17031-17036
-
-
Orjalo, A.V.1
Bhaumik, D.2
Gengler, B.K.3
Scott, G.K.4
Campisi, J.5
-
90
-
-
84880506559
-
Implications of time-series gene expression profiles of replicative senescence
-
Kim YM, Byun HO, Jee BA et al (2013) Implications of time-series gene expression profiles of replicative senescence. Aging Cell 12, 622-634
-
(2013)
Aging Cell
, vol.12
, pp. 622-634
-
-
Kim, Y.M.1
Byun, H.O.2
Jee, B.A.3
-
91
-
-
33847016850
-
Many membrane proteins undergo ectodomain shedding by proteolytic cleavage. Does one sheddase do the job on all of these proteins?
-
Chow FL and Fernandez-Patron C (2007) Many membrane proteins undergo ectodomain shedding by proteolytic cleavage. Does one sheddase do the job on all of these proteins? IUBMB Life 59, 44-47
-
(2007)
IUBMB Life
, vol.59
, pp. 44-47
-
-
Chow, F.L.1
Fernandez-Patron, C.2
-
93
-
-
34547749466
-
c-Met ectodomain shedding rate correlates with malignant potential
-
Athauda G, Giubellino A, Coleman JA et al (2006) c-Met ectodomain shedding rate correlates with malignant potential. Clin Cancer Res 12, 4154-4162
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4154-4162
-
-
Athauda, G.1
Giubellino, A.2
Coleman, J.A.3
-
94
-
-
65549097792
-
A role for CXCR2 in senescence, but what about in cancer?
-
Acosta JC and Gil J (2009) A role for CXCR2 in senescence, but what about in cancer? Cancer Res 69, 2167-2170
-
(2009)
Cancer Res
, vol.69
, pp. 2167-2170
-
-
Acosta, J.C.1
Gil, J.2
-
95
-
-
77952105389
-
Inflammatory networks during cellular senescence: causes and consequences
-
Freund A, Orjalo AV, Desprez PY and Campisi J (2010) Inflammatory networks during cellular senescence: causes and consequences. Trends Mol Med 16, 238-246
-
(2010)
Trends Mol Med
, vol.16
, pp. 238-246
-
-
Freund, A.1
Orjalo, A.V.2
Desprez, P.Y.3
Campisi, J.4
-
96
-
-
84888132393
-
Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage
-
Guo H, Liu Z, Xu B et al (2013) Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage. Aging Cell 12, 1110-1121
-
(2013)
Aging Cell
, vol.12
, pp. 1110-1121
-
-
Guo, H.1
Liu, Z.2
Xu, B.3
-
97
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A and Tabtiang R (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366, 461-464
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
98
-
-
84864360549
-
Plasminogen activator inhibitor 1--insulin-like growth factor binding protein 3 cascade regulates stressinduced senescence
-
Elzi DJ, Lai Y, Song M, Hakala K, Weintraub ST and Shiio Y (2012) Plasminogen activator inhibitor 1--insulin-like growth factor binding protein 3 cascade regulates stressinduced senescence. Proc Natl Acad Sci U S A 109, 12052-12057
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 12052-12057
-
-
Elzi, D.J.1
Lai, Y.2
Song, M.3
Hakala, K.4
Weintraub, S.T.5
Shiio, Y.6
-
99
-
-
81155159806
-
Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts
-
Micutkova L, Diener T, Li C et al (2011) Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts. Mech Ageing Dev 132, 468-479
-
(2011)
Mech Ageing Dev
, vol.132
, pp. 468-479
-
-
Micutkova, L.1
Diener, T.2
Li, C.3
|