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Volumn 12, Issue 1, 2012, Pages 86-99

PGC-1 family coactivators and cell fate: Roles in cancer, neurodegeneration, cardiovascular disease and retrograde mitochondria-nucleus signalling

Author keywords

Apoptosis; Cancer; Cellular stress response; Mitochondrial biogenesis; Neurodegeneration; Pgc 1; Retrograde signalling

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA;

EID: 84856544687     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2011.09.009     Document Type: Review
Times cited : (118)

References (213)
  • 1
    • 77953567491 scopus 로고    scopus 로고
    • Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects
    • Acin-Perez R., Salazar E., Brosel S., Yang H., Schon E.A., Manfredi G. Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects. EMBO Mol. Med. 2009, 1:392-406.
    • (2009) EMBO Mol. Med. , vol.1 , pp. 392-406
    • Acin-Perez, R.1    Salazar, E.2    Brosel, S.3    Yang, H.4    Schon, E.A.5    Manfredi, G.6
  • 2
    • 34548394944 scopus 로고    scopus 로고
    • The effect of training on the expression of mitochondrial biogenesis- and apoptosis-related proteins in skeletal muscle of patients with mtDNA defects
    • Adhihetty P.J., Taivassalo T., Haller R.G., Walkinshaw D.R., Hood D.A. The effect of training on the expression of mitochondrial biogenesis- and apoptosis-related proteins in skeletal muscle of patients with mtDNA defects. Am. J. Physiol. Endocrinol. Metab. 2007, 293:E672-E680.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.293
    • Adhihetty, P.J.1    Taivassalo, T.2    Haller, R.G.3    Walkinshaw, D.R.4    Hood, D.A.5
  • 3
    • 0035901495 scopus 로고    scopus 로고
    • Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion
    • Amuthan G., Biswas G., Zhang S.Y., Klein-Szanto A., Vijayasarathy C., Avadhani N.G. Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion. EMBO J. 2001, 20:1910-1920.
    • (2001) EMBO J. , vol.20 , pp. 1910-1920
    • Amuthan, G.1    Biswas, G.2    Zhang, S.Y.3    Klein-Szanto, A.4    Vijayasarathy, C.5    Avadhani, N.G.6
  • 4
    • 0037038669 scopus 로고    scopus 로고
    • Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
    • Amuthan G., Biswas G., Ananadatheerthavarada H.K., Vijayasarathy C., Shephard H.M., Avadhani N.G. Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene 2002, 21:7839-7849.
    • (2002) Oncogene , vol.21 , pp. 7839-7849
    • Amuthan, G.1    Biswas, G.2    Ananadatheerthavarada, H.K.3    Vijayasarathy, C.4    Shephard, H.M.5    Avadhani, N.G.6
  • 5
    • 0035016566 scopus 로고    scopus 로고
    • Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
    • Andersson U., Scarpulla R.C. Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. Mol. Cell. Biol. 2001, 21:3738-3749.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3738-3749
    • Andersson, U.1    Scarpulla, R.C.2
  • 7
    • 33745627066 scopus 로고    scopus 로고
    • Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha
    • Arany Z., Novikov M., Chin S., Ma Y., Rosenzweig A., Spiegelman B.M. Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:10086-10091.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 10086-10091
    • Arany, Z.1    Novikov, M.2    Chin, S.3    Ma, Y.4    Rosenzweig, A.5    Spiegelman, B.M.6
  • 9
    • 0037080987 scopus 로고    scopus 로고
    • CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
    • Arnould T., Vankoningsloo S., Renard P., Houbion A., Ninane N., Demazy C., Remacle J., Raes M. CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation. EMBO J. 2002, 21:53-63.
    • (2002) EMBO J. , vol.21 , pp. 53-63
    • Arnould, T.1    Vankoningsloo, S.2    Renard, P.3    Houbion, A.4    Ninane, N.5    Demazy, C.6    Remacle, J.7    Raes, M.8
  • 10
    • 34250355048 scopus 로고    scopus 로고
    • Mitochondrial genetic background modifies breast cancer risk
    • Bai R.K., Leal S.M., Covarrubias D., Liu A., Wong L.J. Mitochondrial genetic background modifies breast cancer risk. Cancer Res. 2007, 67:4687-4694.
    • (2007) Cancer Res. , vol.67 , pp. 4687-4694
    • Bai, R.K.1    Leal, S.M.2    Covarrubias, D.3    Liu, A.4    Wong, L.J.5
  • 11
    • 79955664111 scopus 로고    scopus 로고
    • Mitochondrial protein quality control during biogenesis and aging
    • Baker B.M., Haynes C.M. Mitochondrial protein quality control during biogenesis and aging. Trends Biochem. Sci. 2011, 36:254-261.
    • (2011) Trends Biochem. Sci. , vol.36 , pp. 254-261
    • Baker, B.M.1    Haynes, C.M.2
  • 13
    • 0031041464 scopus 로고    scopus 로고
    • Regulation of murine cytochrome oxidase Vb gene expression in different tissues and during myogenesis. Role of a YY-1 factor-binding negative enhancer
    • Basu A., Lenka N., Mullick J., Avadhani N.G. Regulation of murine cytochrome oxidase Vb gene expression in different tissues and during myogenesis. Role of a YY-1 factor-binding negative enhancer. J. Biol. Chem. 1997, 272:5899-5908.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5899-5908
    • Basu, A.1    Lenka, N.2    Mullick, J.3    Avadhani, N.G.4
  • 14
    • 33644946603 scopus 로고    scopus 로고
    • Regulation of Ca2+ signalling and Ca2+-mediated cell death by the transcriptional coactivator PGC-1alpha
    • Bianchi K., Vandecasteele G., Carli C., Romagnoli A., Szabadkai G., Rizzuto R. Regulation of Ca2+ signalling and Ca2+-mediated cell death by the transcriptional coactivator PGC-1alpha. Cell Death Differ. 2006, 13:586-596.
    • (2006) Cell Death Differ. , vol.13 , pp. 586-596
    • Bianchi, K.1    Vandecasteele, G.2    Carli, C.3    Romagnoli, A.4    Szabadkai, G.5    Rizzuto, R.6
  • 15
    • 0033081478 scopus 로고    scopus 로고
    • Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk
    • Biswas G., Adebanjo O.A., Freedman B.D., Anandatheerthavarada H.K., Vijayasarathy C., Zaidi M., Kotlikoff M., Avadhani N.G. Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk. EMBO J. 1999, 18:522-533.
    • (1999) EMBO J. , vol.18 , pp. 522-533
    • Biswas, G.1    Adebanjo, O.A.2    Freedman, B.D.3    Anandatheerthavarada, H.K.4    Vijayasarathy, C.5    Zaidi, M.6    Kotlikoff, M.7    Avadhani, N.G.8
  • 16
    • 14944369831 scopus 로고    scopus 로고
    • Mechanism of mitochondrial stress-induced resistance to apoptosis in mitochondrial DNA-depleted C2C12 myocytes
    • Biswas G., Anandatheerthavarada H.K., Avadhani N.G. Mechanism of mitochondrial stress-induced resistance to apoptosis in mitochondrial DNA-depleted C2C12 myocytes. Cell Death Differ. 2005, 12:266-278.
    • (2005) Cell Death Differ. , vol.12 , pp. 266-278
    • Biswas, G.1    Anandatheerthavarada, H.K.2    Avadhani, N.G.3
  • 17
    • 45549103879 scopus 로고    scopus 로고
    • A distinctive physiological role for IkappaBbeta in the propagation of mitochondrial respiratory stress signaling
    • Biswas G., Tang W., Sondheimer N., Guha M., Bansal S., Avadhani N.G. A distinctive physiological role for IkappaBbeta in the propagation of mitochondrial respiratory stress signaling. J. Biol. Chem. 2008, 283:12586-12594.
    • (2008) J. Biol. Chem. , vol.283 , pp. 12586-12594
    • Biswas, G.1    Tang, W.2    Sondheimer, N.3    Guha, M.4    Bansal, S.5    Avadhani, N.G.6
  • 20
    • 33746466098 scopus 로고    scopus 로고
    • Mitochondrial mutations in cancer
    • Brandon M., Baldi P., Wallace D.C. Mitochondrial mutations in cancer. Oncogene 2006, 25:4647-4662.
    • (2006) Oncogene , vol.25 , pp. 4647-4662
    • Brandon, M.1    Baldi, P.2    Wallace, D.C.3
  • 21
    • 37849022851 scopus 로고    scopus 로고
    • Mitochondrial stress signaling: a pathway unfolds
    • Broadley S.A., Hartl F.U. Mitochondrial stress signaling: a pathway unfolds. Trends Cell Biol. 2008, 18:1-4.
    • (2008) Trends Cell Biol. , vol.18 , pp. 1-4
    • Broadley, S.A.1    Hartl, F.U.2
  • 23
    • 1842665662 scopus 로고    scopus 로고
    • Mitochondrial signaling: the retrograde response
    • Butow R.A., Avadhani N.G. Mitochondrial signaling: the retrograde response. Mol. Cell 2004, 14:1-15.
    • (2004) Mol. Cell , vol.14 , pp. 1-15
    • Butow, R.A.1    Avadhani, N.G.2
  • 27
    • 79955604131 scopus 로고    scopus 로고
    • Genetic insights into OXPHOS defect and its role in cancer
    • Chandra D., Singh K.K. Genetic insights into OXPHOS defect and its role in cancer. Biochim. Biophys. Acta 2010, 1807(6):620-625.
    • (2010) Biochim. Biophys. Acta , vol.1807 , Issue.6 , pp. 620-625
    • Chandra, D.1    Singh, K.K.2
  • 30
    • 0037732600 scopus 로고    scopus 로고
    • LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway
    • Chen E.J., Kaiser C.A. LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway. J. Cell Biol. 2003, 161:333-347.
    • (2003) J. Cell Biol. , vol.161 , pp. 333-347
    • Chen, E.J.1    Kaiser, C.A.2
  • 31
    • 13244277441 scopus 로고    scopus 로고
    • Aconitase couples metabolic regulation to mitochondrial DNA maintenance
    • Chen X.J., Wang X., Kaufman B.A., Butow R.A. Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 2005, 307:714-717.
    • (2005) Science , vol.307 , pp. 714-717
    • Chen, X.J.1    Wang, X.2    Kaufman, B.A.3    Butow, R.A.4
  • 33
    • 79955994007 scopus 로고    scopus 로고
    • Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease
    • Clark J., Reddy S., Zheng K., Betensky R., Simon D. Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease. BMC Med. Genet. 2011, 12:69.
    • (2011) BMC Med. Genet. , vol.12 , pp. 69
    • Clark, J.1    Reddy, S.2    Zheng, K.3    Betensky, R.4    Simon, D.5
  • 37
    • 33749042331 scopus 로고    scopus 로고
    • Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
    • Cui L., Jeong H., Borovecki F., Parkhurst C.N., Tanese N., Krainc D. Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 2006, 127:59-69.
    • (2006) Cell , vol.127 , pp. 59-69
    • Cui, L.1    Jeong, H.2    Borovecki, F.3    Parkhurst, C.N.4    Tanese, N.5    Krainc, D.6
  • 39
    • 0037452677 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor Œ coactivator 1Œ± (PGC-1Œ±) and mitochondrial function by MEF2 and HDAC5
    • Czubryt M.P., McAnally J., Fishman G.I., Olson E.N. Regulation of peroxisome proliferator-activated receptor Œ coactivator 1Œ± (PGC-1Œ±) and mitochondrial function by MEF2 and HDAC5. Proc. Natl. Acad. Sci. 2003, 100:1711-1716.
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , pp. 1711-1716
    • Czubryt, M.P.1    McAnally, J.2    Fishman, G.I.3    Olson, E.N.4
  • 40
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
    • DeBerardinis R.J., Lum J.J., Hatzivassiliou G., Thompson C.B. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 2008, 7:11-20.
    • (2008) Cell Metab. , vol.7 , pp. 11-20
    • DeBerardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 41
    • 78650387482 scopus 로고    scopus 로고
    • Transcriptional control of the ERBB2 amplicon by ERR{alpha} and PGC-1{beta} promotes mammary gland tumorigenesis
    • Deblois G., Chahrour G., Perry M.-C., Sylvain-Drolet G., Muller W.J., Giguère V. Transcriptional control of the ERBB2 amplicon by ERR{alpha} and PGC-1{beta} promotes mammary gland tumorigenesis. Cancer Res. 2010, 70:10277-10287.
    • (2010) Cancer Res. , vol.70 , pp. 10277-10287
    • Deblois, G.1    Chahrour, G.2    Perry, M.-C.3    Sylvain-Drolet, G.4    Muller, W.J.5    Giguère, V.6
  • 42
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W. Free radicals in the physiological control of cell function. Physiol. Rev. 2002, 82:47-95.
    • (2002) Physiol. Rev. , vol.82 , pp. 47-95
    • Droge, W.1
  • 43
    • 79951963668 scopus 로고    scopus 로고
    • Roles of mitochondria in human disease
    • Duchen M.R., Szabadkai G. Roles of mitochondria in human disease. Essays Biochem. 2010, 47:115-137.
    • (2010) Essays Biochem. , vol.47 , pp. 115-137
    • Duchen, M.R.1    Szabadkai, G.2
  • 44
  • 46
    • 0032715653 scopus 로고    scopus 로고
    • Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression
    • Esterbauer H., Oberkofler H., Krempler F., Patsch W. Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression. Genomics 1999, 62:98-102.
    • (1999) Genomics , vol.62 , pp. 98-102
    • Esterbauer, H.1    Oberkofler, H.2    Krempler, F.3    Patsch, W.4
  • 47
    • 28244442462 scopus 로고    scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease
    • Fadeel B., Orrenius S. Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease. J. Intern. Med. 2005, 258:479-517.
    • (2005) J. Intern. Med. , vol.258 , pp. 479-517
    • Fadeel, B.1    Orrenius, S.2
  • 48
    • 0345167182 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARgamma-coactivator 1 (PGC-1)
    • Feilchenfeldt J., Bründler M.A., Soravia C., Tötsch M., Meier C.A. Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARgamma-coactivator 1 (PGC-1). Cancer Lett. 2004, 203:25-33.
    • (2004) Cancer Lett. , vol.203 , pp. 25-33
    • Feilchenfeldt, J.1    Bründler, M.A.2    Soravia, C.3    Tötsch, M.4    Meier, C.A.5
  • 49
    • 10844295852 scopus 로고    scopus 로고
    • Discovery of a major D-loop replication origin reveals two modes of human mtDNA synthesis
    • Fish J., Raule N., Attardi G. Discovery of a major D-loop replication origin reveals two modes of human mtDNA synthesis. Science 2004, 306:2098-2101.
    • (2004) Science , vol.306 , pp. 2098-2101
    • Fish, J.1    Raule, N.2    Attardi, G.3
  • 50
    • 0041923828 scopus 로고    scopus 로고
    • Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor
    • Fjeld C.C., Birdsong W.T., Goodman R.H. Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:9202-9207.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 9202-9207
    • Fjeld, C.C.1    Birdsong, W.T.2    Goodman, R.H.3
  • 52
    • 0141634243 scopus 로고    scopus 로고
    • Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles
    • Garnier A., Fortin D., Deloménie C., Momken I., Veksler V., Ventura-Clapier R. Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles. J. Physiol. 2003, 551:491-501.
    • (2003) J. Physiol. , vol.551 , pp. 491-501
    • Garnier, A.1    Fortin, D.2    Deloménie, C.3    Momken, I.4    Veksler, V.5    Ventura-Clapier, R.6
  • 54
    • 61449226468 scopus 로고    scopus 로고
    • Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand
    • Gohil V.M., Greenberg M.L. Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand. J. Cell Biol. 2009, 184:469-472.
    • (2009) J. Cell Biol. , vol.184 , pp. 469-472
    • Gohil, V.M.1    Greenberg, M.L.2
  • 55
    • 0028049078 scopus 로고
    • Differential regulation of respiratory chain subunits by a CREB-dependent signal transduction pathway. Role of cyclic AMP in cytochrome c and COXIV gene expression
    • Gopalakrishnan L., Scarpulla R.C. Differential regulation of respiratory chain subunits by a CREB-dependent signal transduction pathway. Role of cyclic AMP in cytochrome c and COXIV gene expression. J. Biol. Chem. 1994, 269:105-113.
    • (1994) J. Biol. Chem. , vol.269 , pp. 105-113
    • Gopalakrishnan, L.1    Scarpulla, R.C.2
  • 57
    • 34347210331 scopus 로고    scopus 로고
    • Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress
    • Guha M., Srinivasan S., Biswas G., Avadhani N.G. Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress. J. Biol. Chem. 2007, 282:14536-14546.
    • (2007) J. Biol. Chem. , vol.282 , pp. 14536-14546
    • Guha, M.1    Srinivasan, S.2    Biswas, G.3    Avadhani, N.G.4
  • 58
    • 70350241253 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein A2 is a common transcriptional coactivator in the nuclear transcription response to mitochondrial respiratory stress
    • Guha M., Pan H., Fang J.K., Avadhani N.G. Heterogeneous nuclear ribonucleoprotein A2 is a common transcriptional coactivator in the nuclear transcription response to mitochondrial respiratory stress. Mol. Biol. Cell 2009, 20:4107-4119.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 4107-4119
    • Guha, M.1    Pan, H.2    Fang, J.K.3    Avadhani, N.G.4
  • 59
    • 77958077188 scopus 로고    scopus 로고
    • Activation of Akt is essential for the propagation of mitochondrial respiratory stress signaling and activation of the transcriptional coactivator heterogeneous ribonucleoprotein A2
    • Guha M., Fang J.-K., Monks R., Birnbaum M.J., Avadhani N.G. Activation of Akt is essential for the propagation of mitochondrial respiratory stress signaling and activation of the transcriptional coactivator heterogeneous ribonucleoprotein A2. Mol. Biol. Cell 2010, 21:3578-3589.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 3578-3589
    • Guha, M.1    Fang, J.-K.2    Monks, R.3    Birnbaum, M.J.4    Avadhani, N.G.5
  • 60
    • 67349117275 scopus 로고    scopus 로고
    • What is the mitochondrial permeability transition pore?
    • Halestrap A.P. What is the mitochondrial permeability transition pore?. J. Mol. Cell. Cardiol. 2009, 46:821-831.
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , pp. 821-831
    • Halestrap, A.P.1
  • 61
    • 61549114992 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha
    • Han S., Ritzenthaler J.D., Sun X., Zheng Y., Roman J. Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha. Am. J. Respir. Cell Mol. Biol. 2009, 40:325-331.
    • (2009) Am. J. Respir. Cell Mol. Biol. , vol.40 , pp. 325-331
    • Han, S.1    Ritzenthaler, J.D.2    Sun, X.3    Zheng, Y.4    Roman, J.5
  • 62
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 63
    • 68649109608 scopus 로고    scopus 로고
    • The biology of PGC-1[alpha] and its therapeutic potential
    • Handschin C. The biology of PGC-1[alpha] and its therapeutic potential. Trends Pharmacol. Sci. 2009, 30:322-329.
    • (2009) Trends Pharmacol. Sci. , vol.30 , pp. 322-329
    • Handschin, C.1
  • 65
    • 67651159365 scopus 로고    scopus 로고
    • Transcriptional control of mitochondrial biogenesis and function
    • Hock M.B., Kralli A. Transcriptional control of mitochondrial biogenesis and function. Annu. Rev. Physiol. 2009, 71:177-203.
    • (2009) Annu. Rev. Physiol. , vol.71 , pp. 177-203
    • Hock, M.B.1    Kralli, A.2
  • 66
    • 76749099670 scopus 로고    scopus 로고
    • Zen and the art of mitochondrial DNA maintenance
    • Holt I.J. Zen and the art of mitochondrial DNA maintenance. Trends Genet. 2010, 26:103-109.
    • (2010) Trends Genet. , vol.26 , pp. 103-109
    • Holt, I.J.1
  • 67
    • 0023883150 scopus 로고
    • Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
    • Holt I.J., Harding A.E., Morgan-Hughes J.A. Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature 1988, 331:717-719.
    • (1988) Nature , vol.331 , pp. 717-719
    • Holt, I.J.1    Harding, A.E.2    Morgan-Hughes, J.A.3
  • 68
    • 77951247838 scopus 로고    scopus 로고
    • StarD7 mediates the intracellular trafficking of phosphatidylcholine to mitochondria
    • Horibata Y., Sugimoto H. StarD7 mediates the intracellular trafficking of phosphatidylcholine to mitochondria. J. Biol. Chem. 2010, 285:7358-7365.
    • (2010) J. Biol. Chem. , vol.285 , pp. 7358-7365
    • Horibata, Y.1    Sugimoto, H.2
  • 69
    • 37849038317 scopus 로고    scopus 로고
    • The Chop gene contains an element for the positive regulation of the mitochondrial unfolded protein response
    • Horibe T., Hoogenraad N.J. The Chop gene contains an element for the positive regulation of the mitochondrial unfolded protein response. PLoS One 2007, 2:e835.
    • (2007) PLoS One , vol.2
    • Horibe, T.1    Hoogenraad, N.J.2
  • 70
    • 4644231528 scopus 로고    scopus 로고
    • Nuclear receptor signaling and cardiac energetics
    • Huss J.M., Kelly D.P. Nuclear receptor signaling and cardiac energetics. Circ. Res. 2004, 95:568-578.
    • (2004) Circ. Res. , vol.95 , pp. 568-578
    • Huss, J.M.1    Kelly, D.P.2
  • 71
    • 58349118928 scopus 로고    scopus 로고
    • Interactions between ROS and AMP kinase activity in the regulation of PGC-1Œ± transcription in skeletal muscle cells
    • Irrcher I., Ljubicic V., Hood D.A. Interactions between ROS and AMP kinase activity in the regulation of PGC-1Œ± transcription in skeletal muscle cells. Am. J. Physiol. Cell Physiol. 2009, 296:C116-C123.
    • (2009) Am. J. Physiol. Cell Physiol. , vol.296
    • Irrcher, I.1    Ljubicic, V.2    Hood, D.A.3
  • 74
    • 77955918482 scopus 로고    scopus 로고
    • Reversible acetylation of PGC-1: connecting energy sensors and effectors to guarantee metabolic flexibility
    • Jeninga E.H., Schoonjans K., Auwerx J. Reversible acetylation of PGC-1: connecting energy sensors and effectors to guarantee metabolic flexibility. Oncogene 2010, 29:4617-4624.
    • (2010) Oncogene , vol.29 , pp. 4617-4624
    • Jeninga, E.H.1    Schoonjans, K.2    Auwerx, J.3
  • 75
    • 0042524273 scopus 로고    scopus 로고
    • Expression of peroxisome-proliferator activated receptor-gamma (PPARgamma) and the PPARgamma co-activator, PGC-1, in human breast cancer correlates with clinical outcomes
    • Jiang W.G., Douglas-Jones A., Mansel R.E. Expression of peroxisome-proliferator activated receptor-gamma (PPARgamma) and the PPARgamma co-activator, PGC-1, in human breast cancer correlates with clinical outcomes. Int. J. Cancer 2003, 106:752-757.
    • (2003) Int. J. Cancer , vol.106 , pp. 752-757
    • Jiang, W.G.1    Douglas-Jones, A.2    Mansel, R.E.3
  • 76
    • 55149107716 scopus 로고    scopus 로고
    • Radical-free biology of oxidative stress
    • Jones D.P. Radical-free biology of oxidative stress. Am. J. Physiol. Cell Physiol. 2008, 295:849-868.
    • (2008) Am. J. Physiol. Cell Physiol. , vol.295 , pp. 849-868
    • Jones, D.P.1
  • 77
    • 2142762462 scopus 로고    scopus 로고
    • Compensatory responses of protein import and transcription factor expression in mitochondrial DNA defects
    • Joseph A.M., Rungi A.A., Robinson B.H., Hood D.A. Compensatory responses of protein import and transcription factor expression in mitochondrial DNA defects. Am. J. Physiol. Cell Physiol. 2004, 286:C867-C875.
    • (2004) Am. J. Physiol. Cell Physiol. , vol.286
    • Joseph, A.M.1    Rungi, A.A.2    Robinson, B.H.3    Hood, D.A.4
  • 78
    • 77955299384 scopus 로고    scopus 로고
    • Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial cybrids
    • Kaipparettu B.A., Ma Y., Wong L.J. Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial cybrids. Ann. N. Y. Acad. Sci. 2010, 1201:137-146.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1201 , pp. 137-146
    • Kaipparettu, B.A.1    Ma, Y.2    Wong, L.J.3
  • 80
    • 77950245008 scopus 로고    scopus 로고
    • Transcriptional control of brown fat development
    • Kajimura S., Seale P., Spiegelman B.M. Transcriptional control of brown fat development. Cell Metab. 2010, 11:257-262.
    • (2010) Cell Metab. , vol.11 , pp. 257-262
    • Kajimura, S.1    Seale, P.2    Spiegelman, B.M.3
  • 81
    • 1542373685 scopus 로고    scopus 로고
    • Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
    • Kelly D.P., Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 2004, 18:357-368.
    • (2004) Genes Dev. , vol.18 , pp. 357-368
    • Kelly, D.P.1    Scarpulla, R.C.2
  • 82
    • 57349115353 scopus 로고    scopus 로고
    • Estrogenic control of mitochondrial function and biogenesis
    • Klinge C.M. Estrogenic control of mitochondrial function and biogenesis. J. Cell. Biochem. 2008, 105:1342-1351.
    • (2008) J. Cell. Biochem. , vol.105 , pp. 1342-1351
    • Klinge, C.M.1
  • 83
    • 70349333218 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator-1 alpha enhances antiproliferative activity of 5J-deoxy-5-fluorouridine in cancer cells through induction of uridine phosphorylase
    • Kong X., Fan H., Liu X., Wang R., Liang J., Gupta N., Chen Y., Fang F., Chang Y. Peroxisome proliferator-activated receptor gamma coactivator-1 alpha enhances antiproliferative activity of 5J-deoxy-5-fluorouridine in cancer cells through induction of uridine phosphorylase. Mol. Pharmacol. 2009, 76:854-860.
    • (2009) Mol. Pharmacol. , vol.76 , pp. 854-860
    • Kong, X.1    Fan, H.2    Liu, X.3    Wang, R.4    Liang, J.5    Gupta, N.6    Chen, Y.7    Fang, F.8    Chang, Y.9
  • 84
    • 0037134493 scopus 로고    scopus 로고
    • The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha
    • Kressler D., Schreiber S.N., Knutti D., Kralli A. The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha. J. Biol. Chem. 2002, 277:13918-13925.
    • (2002) J. Biol. Chem. , vol.277 , pp. 13918-13925
    • Kressler, D.1    Schreiber, S.N.2    Knutti, D.3    Kralli, A.4
  • 87
    • 76249097338 scopus 로고    scopus 로고
    • Cancer cell mitochondria confer apoptosis resistance and promote metastasis
    • Kulawiec M., Owens K.M., Singh K.K. Cancer cell mitochondria confer apoptosis resistance and promote metastasis. Cancer Biol. Ther. 2009, 8:1378-1385.
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 1378-1385
    • Kulawiec, M.1    Owens, K.M.2    Singh, K.K.3
  • 88
    • 77953490673 scopus 로고    scopus 로고
    • Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer
    • Kulawiec M., Salk J.J., Ericson N.G., Wanagat J., Bielas J.H. Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer. Environ. Mol. Mutagen. 2010, 51:427-439.
    • (2010) Environ. Mol. Mutagen. , vol.51 , pp. 427-439
    • Kulawiec, M.1    Salk, J.J.2    Ericson, N.G.3    Wanagat, J.4    Bielas, J.H.5
  • 89
    • 47549114849 scopus 로고    scopus 로고
    • Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart
    • Lai L., Leone T.C., Zechner C., Schaeffer P.J., Kelly S.M., Flanagan D.P., Medeiros D.M., Kovacs A., Kelly D.P. Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart. Genes Dev. 2008, 22:1948-1961.
    • (2008) Genes Dev. , vol.22 , pp. 1948-1961
    • Lai, L.1    Leone, T.C.2    Zechner, C.3    Schaeffer, P.J.4    Kelly, S.M.5    Flanagan, D.P.6    Medeiros, D.M.7    Kovacs, A.8    Kelly, D.P.9
  • 91
    • 79959245405 scopus 로고    scopus 로고
    • Aberrant cell proliferation by enhanced mitochondrial biogenesis via mtTFA in arsenical skin cancers
    • Lee C.-H., Wu S.-B., Hong C.-H., Liao W.-T., Wu C.-Y., Chen G.-S., Wei Y.-H., Yu H.-S. Aberrant cell proliferation by enhanced mitochondrial biogenesis via mtTFA in arsenical skin cancers. Am. J. Pathol. 2011, 178:2066-2076.
    • (2011) Am. J. Pathol. , vol.178 , pp. 2066-2076
    • Lee, C.-H.1    Wu, S.-B.2    Hong, C.-H.3    Liao, W.-T.4    Wu, C.-Y.5    Chen, G.-S.6    Wei, Y.-H.7    Yu, H.-S.8
  • 93
    • 0029965548 scopus 로고    scopus 로고
    • The role of an E box binding basic helix loop helix protein in the cardiac muscle-specific expression of the rat cytochrome oxidase subunit VIII gene
    • Lenka N., Basu A., Mullick J., Avadhani N.G. The role of an E box binding basic helix loop helix protein in the cardiac muscle-specific expression of the rat cytochrome oxidase subunit VIII gene. J. Biol. Chem. 1996, 271:30281-30289.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30281-30289
    • Lenka, N.1    Basu, A.2    Mullick, J.3    Avadhani, N.G.4
  • 95
    • 0026085418 scopus 로고
    • Intramitochondrial functions regulate nonmitochondrial citrate synthase (CIT2) expression in Saccharomyces cerevisiae
    • Liao X.S., Small W.C., Srere P.A., Butow R.A. Intramitochondrial functions regulate nonmitochondrial citrate synthase (CIT2) expression in Saccharomyces cerevisiae. Mol. Cell. Biol. 1991, 11:38-46.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 38-46
    • Liao, X.S.1    Small, W.C.2    Srere, P.A.3    Butow, R.A.4
  • 96
    • 77957223368 scopus 로고    scopus 로고
    • Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor gamma co-activator-1alpha protein
    • Liao X., Wang Y., Wong C.W. Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor gamma co-activator-1alpha protein. Br. J. Pharmacol. 2010, 161:771-781.
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 771-781
    • Liao, X.1    Wang, Y.2    Wong, C.W.3
  • 97
    • 58149240182 scopus 로고    scopus 로고
    • Minireview: the PGC-1 coactivator networks: chromatin-remodeling and mitochondrial energy metabolism
    • Lin J.D. Minireview: the PGC-1 coactivator networks: chromatin-remodeling and mitochondrial energy metabolism. Mol. Endocrinol. 2009, 23:2-10.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 2-10
    • Lin, J.D.1
  • 98
    • 0037127204 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta), a novel PGC-1-related transcription coactivator associated with host cell factor
    • Lin J., Puigserver P., Donovan J., Tarr P., Spiegelman B.M. Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta), a novel PGC-1-related transcription coactivator associated with host cell factor. J. Biol. Chem. 2002, 277:1645-1648.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1645-1648
    • Lin, J.1    Puigserver, P.2    Donovan, J.3    Tarr, P.4    Spiegelman, B.M.5
  • 99
    • 0037081814 scopus 로고    scopus 로고
    • High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
    • Lin M.T., Simon D.K., Ahn C.H., Kim L.M., Beal M.F. High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain. Hum. Mol. Genet. 2002, 11:133-145.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 133-145
    • Lin, M.T.1    Simon, D.K.2    Ahn, C.H.3    Kim, L.M.4    Beal, M.F.5
  • 101
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin J., Handschin C., Spiegelman B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 2005, 1:361-370.
    • (2005) Cell Metab. , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 104
    • 33845656956 scopus 로고    scopus 로고
    • Mitochondrial retrograde signaling
    • Liu Z., Butow R.A. Mitochondrial retrograde signaling. Annu. Rev. Genet. 2006, 40:159-185.
    • (2006) Annu. Rev. Genet. , vol.40 , pp. 159-185
    • Liu, Z.1    Butow, R.A.2
  • 105
    • 0037126596 scopus 로고    scopus 로고
    • RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p
    • Liu Z., Sekito T., Epstein C.B., Butow R.A. RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p. EMBO J. 2001, 20:7209-7219.
    • (2001) EMBO J. , vol.20 , pp. 7209-7219
    • Liu, Z.1    Sekito, T.2    Epstein, C.B.3    Butow, R.A.4
  • 107
    • 78049393407 scopus 로고    scopus 로고
    • Mitochondrial protein quality control systems in aging and disease
    • Luce K., Weil A.C., Osiewacz H.D. Mitochondrial protein quality control systems in aging and disease. Adv. Exp. Med. Biol. 2010, 694:108-125.
    • (2010) Adv. Exp. Med. Biol. , vol.694 , pp. 108-125
    • Luce, K.1    Weil, A.C.2    Osiewacz, H.D.3
  • 108
    • 0035658286 scopus 로고    scopus 로고
    • Uncoupling of mitochondria activates protein phosphatases and inactivates MBP protein kinases
    • Luo Y., Ingram V.M. Uncoupling of mitochondria activates protein phosphatases and inactivates MBP protein kinases. J. Alzheimers Dis. 2001, 3:593-598.
    • (2001) J. Alzheimers Dis. , vol.3 , pp. 593-598
    • Luo, Y.1    Ingram, V.M.2
  • 109
    • 0030886976 scopus 로고    scopus 로고
    • Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP,Äâkinases
    • Luo Y., Bond J.D., Ingram V.M. Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP,Äâkinases. Proc. Natl. Acad. Sci. 1997, 94:9705-9710.
    • (1997) Proc. Natl. Acad. Sci. , vol.94 , pp. 9705-9710
    • Luo, Y.1    Bond, J.D.2    Ingram, V.M.3
  • 110
    • 74149091370 scopus 로고    scopus 로고
    • NMDA receptor dependent PGC-1alpha up-regulation protects the cortical neuron against oxygen-glucose deprivation/reperfusion injury
    • Luo Y., Zhu W., Jia J., Zhang C., Xu Y. NMDA receptor dependent PGC-1alpha up-regulation protects the cortical neuron against oxygen-glucose deprivation/reperfusion injury. J. Molecular Neurosci. MN 2009, 39:262-268.
    • (2009) J. Molecular Neurosci. MN , vol.39 , pp. 262-268
    • Luo, Y.1    Zhu, W.2    Jia, J.3    Zhang, C.4    Xu, Y.5
  • 112
    • 0037094434 scopus 로고    scopus 로고
    • Nitrogen regulation in Saccharomyces cerevisiae
    • Magasanik B., Kaiser C.A. Nitrogen regulation in Saccharomyces cerevisiae. Gene 2002, 290:1-18.
    • (2002) Gene , vol.290 , pp. 1-18
    • Magasanik, B.1    Kaiser, C.A.2
  • 113
    • 78649364332 scopus 로고    scopus 로고
    • Hypoxia-inducible factors and the response to hypoxic stress
    • Majmundar A.J., Wong W.J., Simon M.C. Hypoxia-inducible factors and the response to hypoxic stress. Mol. Cell 2010, 40:294-309.
    • (2010) Mol. Cell , vol.40 , pp. 294-309
    • Majmundar, A.J.1    Wong, W.J.2    Simon, M.C.3
  • 114
    • 79953000879 scopus 로고    scopus 로고
    • Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells
    • Mandal S., Lindgren A.G., Srivastava A.S., Clark A.T., Banerjee U. Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells. Stem Cells 2011, 29:486-495.
    • (2011) Stem Cells , vol.29 , pp. 486-495
    • Mandal, S.1    Lindgren, A.G.2    Srivastava, A.S.3    Clark, A.T.4    Banerjee, U.5
  • 115
    • 76849089486 scopus 로고    scopus 로고
    • Thyroid hormone and myocardial mitochondrial biogenesis
    • Marin-Garcia J. Thyroid hormone and myocardial mitochondrial biogenesis. Vascul. Pharmacol. 2010, 52:120-130.
    • (2010) Vascul. Pharmacol. , vol.52 , pp. 120-130
    • Marin-Garcia, J.1
  • 116
    • 79957509694 scopus 로고    scopus 로고
    • Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter
    • Martin E., Betuing S., Pagès C., Cambon K., Auregan G., Deglon N., Roze E., Caboche J. Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter. Hum. Mol. Genet. 2011, 20:2422-2434.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 2422-2434
    • Martin, E.1    Betuing, S.2    Pagès, C.3    Cambon, K.4    Auregan, G.5    Deglon, N.6    Roze, E.7    Caboche, J.8
  • 118
    • 0000004493 scopus 로고    scopus 로고
    • Expression of mtDNA and nDNA encoded respiratory chain proteins in chemically and genetically-derived Rho0 human fibroblasts: a comparison of subunit proteins in normal fibroblasts treated with ethidium bromide and fibroblasts from a patient with mtDNA depletion syndrome
    • Marusich M.F., Robinson B.H., Taanman J.-W., Kim S.J., Schillace R., Smith J.L., Capaldi R.A. Expression of mtDNA and nDNA encoded respiratory chain proteins in chemically and genetically-derived Rho0 human fibroblasts: a comparison of subunit proteins in normal fibroblasts treated with ethidium bromide and fibroblasts from a patient with mtDNA depletion syndrome. Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1997, 1362:145-159.
    • (1997) Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. , vol.1362 , pp. 145-159
    • Marusich, M.F.1    Robinson, B.H.2    Taanman, J.-W.3    Kim, S.J.4    Schillace, R.5    Smith, J.L.6    Capaldi, R.A.7
  • 120
    • 0037342698 scopus 로고    scopus 로고
    • Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes
    • McCammon M.T., Epstein C.B., Przybyla-Zawislak B., McAlister-Henn L., Butow R.A. Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes. Mol. Biol. Cell 2003, 14:958-972.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 958-972
    • McCammon, M.T.1    Epstein, C.B.2    Przybyla-Zawislak, B.3    McAlister-Henn, L.4    Butow, R.A.5
  • 121
    • 60849098436 scopus 로고    scopus 로고
    • Effect of thyroid hormone on mitochondrial properties and oxidative stress in cells from patients with mtDNA defects
    • Menzies K.J., Robinson B.H., Hood D.A. Effect of thyroid hormone on mitochondrial properties and oxidative stress in cells from patients with mtDNA defects. Am. J. Physiol. Cell Physiol. 2009, 296:C355-C362.
    • (2009) Am. J. Physiol. Cell Physiol. , vol.296
    • Menzies, K.J.1    Robinson, B.H.2    Hood, D.A.3
  • 122
    • 26244465857 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+-dependent pathway and a reduced mitochondrial protein import
    • Mercy L., Pauw A., Payen L., Tejerina S., Houbion A., Demazy C., Raes M., Renard P., Arnould T. Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+-dependent pathway and a reduced mitochondrial protein import. FEBS J. 2005, 272:5031-5055.
    • (2005) FEBS J. , vol.272 , pp. 5031-5055
    • Mercy, L.1    Pauw, A.2    Payen, L.3    Tejerina, S.4    Houbion, A.5    Demazy, C.6    Raes, M.7    Renard, P.8    Arnould, T.9
  • 123
    • 69349091599 scopus 로고    scopus 로고
    • PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss
    • Miglio G., Rosa A.C., Rattazzi L., Collino M., Lombardi G., Fantozzi R. PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss. Neurochem. Int. 2009, 55:496-504.
    • (2009) Neurochem. Int. , vol.55 , pp. 496-504
    • Miglio, G.1    Rosa, A.C.2    Rattazzi, L.3    Collino, M.4    Lombardi, G.5    Fantozzi, R.6
  • 124
    • 0033614441 scopus 로고    scopus 로고
    • Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells
    • Miranda S., Foncea R., Guerrero J., Leighton F. Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells. Biochem. Biophys. Res. Commun. 1999, 258:44-49.
    • (1999) Biochem. Biophys. Res. Commun. , vol.258 , pp. 44-49
    • Miranda, S.1    Foncea, R.2    Guerrero, J.3    Leighton, F.4
  • 125
    • 75149134754 scopus 로고    scopus 로고
    • Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria
    • Mirebeau-Prunier D., Le Pennec S., Jacques C., Gueguen N., Poirier J., Malthiery Y., Savagner F. Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria. FEBS J. 2010, 277:713-725.
    • (2010) FEBS J. , vol.277 , pp. 713-725
    • Mirebeau-Prunier, D.1    Le Pennec, S.2    Jacques, C.3    Gueguen, N.4    Poirier, J.5    Malthiery, Y.6    Savagner, F.7
  • 126
    • 56849084137 scopus 로고    scopus 로고
    • Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model
    • Miwa S., Lawless C., von Zglinicki T. Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model. Aging Cell 2008, 7:920-923.
    • (2008) Aging Cell , vol.7 , pp. 920-923
    • Miwa, S.1    Lawless, C.2    von Zglinicki, T.3
  • 131
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy M.P. How mitochondria produce reactive oxygen species. Biochem. J. 2009, 417:1-13.
    • (2009) Biochem. J. , vol.417 , pp. 1-13
    • Murphy, M.P.1
  • 132
    • 18144411313 scopus 로고    scopus 로고
    • SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1Œ±
    • Nemoto S., Fergusson M.M., Finkel T. SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1Œ±. J. Biol. Chem. 2005, 280:16456-16460.
    • (2005) J. Biol. Chem. , vol.280 , pp. 16456-16460
    • Nemoto, S.1    Fergusson, M.M.2    Finkel, T.3
  • 134
    • 70350537033 scopus 로고    scopus 로고
    • Nuclear receptor coregulators in cancer biology
    • O'Malley B.W., Kumar R. Nuclear receptor coregulators in cancer biology. Cancer Res. 2009, 69:8217-8222.
    • (2009) Cancer Res. , vol.69 , pp. 8217-8222
    • O'Malley, B.W.1    Kumar, R.2
  • 136
    • 39749104169 scopus 로고    scopus 로고
    • Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint
    • Owusu-Ansah E., Yavari A., Mandal S., Banerjee U. Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint. Nat. Genet. 2008, 40:356-361.
    • (2008) Nat. Genet. , vol.40 , pp. 356-361
    • Owusu-Ansah, E.1    Yavari, A.2    Mandal, S.3    Banerjee, U.4
  • 138
    • 0023106633 scopus 로고
    • The mitochondrial genotype can influence nuclear gene expression in yeast
    • Parikh V.S., Morgan M.M., Scott R., Clements L.S., Butow R.A. The mitochondrial genotype can influence nuclear gene expression in yeast. Science 1987, 235:576-580.
    • (1987) Science , vol.235 , pp. 576-580
    • Parikh, V.S.1    Morgan, M.M.2    Scott, R.3    Clements, L.S.4    Butow, R.A.5
  • 139
    • 33644852502 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1
    • Piantadosi C.A., Suliman H.B. Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1. J. Biol. Chem. 2006, 281:324-333.
    • (2006) J. Biol. Chem. , vol.281 , pp. 324-333
    • Piantadosi, C.A.1    Suliman, H.B.2
  • 140
    • 77956391459 scopus 로고    scopus 로고
    • Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35
    • Potting C., Wilmes C., Engmann T., Osman C., Langer T. Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35. EMBO J. 2010, 29:2888-2898.
    • (2010) EMBO J. , vol.29 , pp. 2888-2898
    • Potting, C.1    Wilmes, C.2    Engmann, T.3    Osman, C.4    Langer, T.5
  • 142
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P., Wu Z., Park C.W., Graves R., Wright M., Spiegelman B.M. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998, 92:829-839.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 144
    • 78650176538 scopus 로고    scopus 로고
    • Protection against dexamethasone-induced muscle atrophy is related to modulation by testosterone of FOXO1 and PGC-1[alpha]
    • Qin W., Pan J., Wu Y., Bauman W.A., Cardozo C. Protection against dexamethasone-induced muscle atrophy is related to modulation by testosterone of FOXO1 and PGC-1[alpha]. Biochem. Biophys. Res. Commun. 2010, 403:473-478.
    • (2010) Biochem. Biophys. Res. Commun. , vol.403 , pp. 473-478
    • Qin, W.1    Pan, J.2    Wu, Y.3    Bauman, W.A.4    Cardozo, C.5
  • 147
    • 57649210205 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in disease, aging, and neurodegeneration
    • Reeve A.K., Krishnan K.J., Turnbull D. Mitochondrial DNA mutations in disease, aging, and neurodegeneration. Ann. N. Y. Acad. Sci. 2008, 1147:21-29.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1147 , pp. 21-29
    • Reeve, A.K.1    Krishnan, K.J.2    Turnbull, D.3
  • 149
    • 71549151624 scopus 로고    scopus 로고
    • Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells
    • Roberts A.M., Watson I.R., Evans A.J., Foster D.A., Irwin M.S., Ohh M. Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells. Cancer Res. 2009, 69:9056-9064.
    • (2009) Cancer Res. , vol.69 , pp. 9056-9064
    • Roberts, A.M.1    Watson, I.R.2    Evans, A.J.3    Foster, D.A.4    Irwin, M.S.5    Ohh, M.6
  • 151
    • 12144286554 scopus 로고    scopus 로고
    • Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor Œ-coactivator-1Œ± promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner
    • Russell L.K., Mansfield C.M., Lehman J.J., Kovacs A., Courtois M., Saffitz J.E., Medeiros D.M., Valencik M.L., McDonald J.A., Kelly D.P. Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor Œ-coactivator-1Œ± promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner. Circ. Res. 2004, 94:525-533.
    • (2004) Circ. Res. , vol.94 , pp. 525-533
    • Russell, L.K.1    Mansfield, C.M.2    Lehman, J.J.3    Kovacs, A.4    Courtois, M.5    Saffitz, J.E.6    Medeiros, D.M.7    Valencik, M.L.8    McDonald, J.A.9    Kelly, D.P.10
  • 154
    • 33645011201 scopus 로고    scopus 로고
    • Nuclear control of respiratory gene expression in mammalian cells
    • Scarpulla R.C. Nuclear control of respiratory gene expression in mammalian cells. J. Cell. Biochem. 2006, 97:673-683.
    • (2006) J. Cell. Biochem. , vol.97 , pp. 673-683
    • Scarpulla, R.C.1
  • 155
    • 57649148823 scopus 로고    scopus 로고
    • Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator
    • Scarpulla R.C. Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator. Ann. N. Y. Acad. Sci. 2008, 1147:321-334.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1147 , pp. 321-334
    • Scarpulla, R.C.1
  • 156
    • 42049114034 scopus 로고    scopus 로고
    • Transcriptional paradigms in mammalian mitochondrial biogenesis and function
    • Scarpulla R.C. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol. Rev. 2008, 88:611-638.
    • (2008) Physiol. Rev. , vol.88 , pp. 611-638
    • Scarpulla, R.C.1
  • 157
    • 79957960940 scopus 로고    scopus 로고
    • Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network Biochim
    • Scarpulla R.C. Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network Biochim. Biophys. Acta 2011, 1813(7):1269-1278.
    • (2011) Biophys. Acta , vol.1813 , Issue.7 , pp. 1269-1278
    • Scarpulla, R.C.1
  • 158
    • 77956090193 scopus 로고    scopus 로고
    • Mitochondrial protein import: from proteomics to functional mechanisms
    • Schmidt O., Pfanner N., Meisinger C. Mitochondrial protein import: from proteomics to functional mechanisms. Nat. Rev. Mol. Cell Biol. 2010, 11:655-667.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 655-667
    • Schmidt, O.1    Pfanner, N.2    Meisinger, C.3
  • 160
    • 73549114238 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator-1alpha interacts with the androgen receptor (AR) and promotes prostate cancer cell growth by activating the AR
    • Shiota M., Yokomizo A., Tada Y., Inokuchi J., Tatsugami K., Kuroiwa K., Uchiumi T., Fujimoto N., Seki N., Naito S. Peroxisome proliferator-activated receptor gamma coactivator-1alpha interacts with the androgen receptor (AR) and promotes prostate cancer cell growth by activating the AR. Mol. Endocrinol. (Baltimore, Md.) 2010, 24:114-127.
    • (2010) Mol. Endocrinol. (Baltimore, Md.) , vol.24 , pp. 114-127
    • Shiota, M.1    Yokomizo, A.2    Tada, Y.3    Inokuchi, J.4    Tatsugami, K.5    Kuroiwa, K.6    Uchiumi, T.7    Fujimoto, N.8    Seki, N.9    Naito, S.10
  • 161
    • 0025276996 scopus 로고
    • Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease
    • Shoubridge E.A., Karpati G., Hastings K.E. Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease. Cell 1990, 62:43-49.
    • (1990) Cell , vol.62 , pp. 43-49
    • Shoubridge, E.A.1    Karpati, G.2    Hastings, K.E.3
  • 162
    • 77953529585 scopus 로고    scopus 로고
    • A compendium of human mitochondrial gene expression machinery with links to disease
    • Shutt T.E., Shadel G.S. A compendium of human mitochondrial gene expression machinery with links to disease. Environ. Mol. Mutagen. 2010, 51:360-379.
    • (2010) Environ. Mol. Mutagen. , vol.51 , pp. 360-379
    • Shutt, T.E.1    Shadel, G.S.2
  • 166
    • 4644351698 scopus 로고    scopus 로고
    • High frequency of mitochondrial complex I mutations in Parkinson's disease and aging
    • Smigrodzki R., Parks J., Parker W.D. High frequency of mitochondrial complex I mutations in Parkinson's disease and aging. Neurobiol. Aging 2004, 25:1273-1281.
    • (2004) Neurobiol. Aging , vol.25 , pp. 1273-1281
    • Smigrodzki, R.1    Parks, J.2    Parker, W.D.3
  • 167
  • 168
    • 78249243079 scopus 로고    scopus 로고
    • Comparing the yeast retrograde response and NF-κB stress responses: implications for aging
    • Srinivasan V., Kriete A., Sacan A., Michal Jazwinski S. Comparing the yeast retrograde response and NF-κB stress responses: implications for aging. Aging Cell 2010, 9:933-941.
    • (2010) Aging Cell , vol.9 , pp. 933-941
    • Srinivasan, V.1    Kriete, A.2    Sacan, A.3    Michal Jazwinski, S.4
  • 169
    • 34447338862 scopus 로고    scopus 로고
    • PGC-1alpha/beta upregulation is associated with improved oxidative phosphorylation in cells harboring nonsense mtDNA mutations
    • Srivastava S., Barrett J.N., Moraes C.T. PGC-1alpha/beta upregulation is associated with improved oxidative phosphorylation in cells harboring nonsense mtDNA mutations. Hum. Mol. Genet. 2007, 16:993-1005.
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 993-1005
    • Srivastava, S.1    Barrett, J.N.2    Moraes, C.T.3
  • 170
    • 0038036024 scopus 로고    scopus 로고
    • Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells
    • St-Pierre J., Lin J., Krauss S., Tarr P.T., Yang R., Newgard C.B., Spiegelman B.M. Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J. Biol. Chem. 2003, 278:26597-26603.
    • (2003) J. Biol. Chem. , vol.278 , pp. 26597-26603
    • St-Pierre, J.1    Lin, J.2    Krauss, S.3    Tarr, P.T.4    Yang, R.5    Newgard, C.B.6    Spiegelman, B.M.7
  • 172
    • 0032547237 scopus 로고    scopus 로고
    • Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells
    • Suzuki H., Kumagai T., Goto A., Sugiura T. Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells. Biochem. Biophys. Res. Commun. 1998, 249:542-545.
    • (1998) Biochem. Biophys. Res. Commun. , vol.249 , pp. 542-545
    • Suzuki, H.1    Kumagai, T.2    Goto, A.3    Sugiura, T.4
  • 173
    • 68949158352 scopus 로고    scopus 로고
    • The neurodegenerative mitochondriopathies
    • Swerdlow R.H. The neurodegenerative mitochondriopathies. J. Alzheimers Dis. 2009, 17:737-751.
    • (2009) J. Alzheimers Dis. , vol.17 , pp. 737-751
    • Swerdlow, R.H.1
  • 175
    • 67449138848 scopus 로고    scopus 로고
    • Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria
    • Tamura Y., Endo T., Iijima M., Sesaki H. Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria. J. Cell Biol. 2009, 185:1029-1045.
    • (2009) J. Cell Biol. , vol.185 , pp. 1029-1045
    • Tamura, Y.1    Endo, T.2    Iijima, M.3    Sesaki, H.4
  • 176
    • 38549101188 scopus 로고    scopus 로고
    • Quality control of mitochondria: protection against neurodegeneration and ageing
    • Tatsuta T., Langer T. Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J. 2008, 27:306-314.
    • (2008) EMBO J. , vol.27 , pp. 306-314
    • Tatsuta, T.1    Langer, T.2
  • 177
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • Taylor R.W., Turnbull D.M. Mitochondrial DNA mutations in human disease. Nat. Rev. Genet. 2005, 6:389-402.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.M.2
  • 180
    • 49349102894 scopus 로고    scopus 로고
    • Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view
    • Twig G., Hyde B., Shirihai O.S. Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim. Biophys. Acta 2008, 1777:1092-1097.
    • (2008) Biochim. Biophys. Acta , vol.1777 , pp. 1092-1097
    • Twig, G.1    Hyde, B.2    Shirihai, O.S.3
  • 181
    • 19444365211 scopus 로고    scopus 로고
    • PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells
    • Valle I., Alvarez-Barrientos A., Arza E., Lamas S., Monsalve M. PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc. Res. 2005, 66:562-573.
    • (2005) Cardiovasc. Res. , vol.66 , pp. 562-573
    • Valle, I.1    Alvarez-Barrientos, A.2    Arza, E.3    Lamas, S.4    Monsalve, M.5
  • 182
    • 2342572271 scopus 로고    scopus 로고
    • Phospholipid biosynthesis in mammalian cells
    • Vance J.E., Vance D.E. Phospholipid biosynthesis in mammalian cells. Biochem. Cell Biol. 2004, 82:113-128.
    • (2004) Biochem. Cell Biol. , vol.82 , pp. 113-128
    • Vance, J.E.1    Vance, D.E.2
  • 183
    • 33749630419 scopus 로고    scopus 로고
    • PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth
    • Vercauteren K., Pasko R.A., Gleyzer N., Marino V.M., Scarpulla R.C. PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth. Mol. Cell. Biol. 2006, 26:7409-7419.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 7409-7419
    • Vercauteren, K.1    Pasko, R.A.2    Gleyzer, N.3    Marino, V.M.4    Scarpulla, R.C.5
  • 184
    • 59049089797 scopus 로고    scopus 로고
    • Short hairpin RNA-mediated silencing of PRC (PGC-1-related coactivator) results in a severe respiratory chain deficiency associated with the proliferation of aberrant mitochondria
    • Vercauteren K., Gleyzer N., Scarpulla R.C. Short hairpin RNA-mediated silencing of PRC (PGC-1-related coactivator) results in a severe respiratory chain deficiency associated with the proliferation of aberrant mitochondria. J. Biol. Chem. 2009, 284:2307-2319.
    • (2009) J. Biol. Chem. , vol.284 , pp. 2307-2319
    • Vercauteren, K.1    Gleyzer, N.2    Scarpulla, R.C.3
  • 187
    • 34548614520 scopus 로고    scopus 로고
    • Why do we still have a maternally inherited mitochondrial DNA? Insights from evolutionary medicine
    • Wallace D.C. Why do we still have a maternally inherited mitochondrial DNA? Insights from evolutionary medicine. Annu. Rev. Biochem. 2007, 76:781-821.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 781-821
    • Wallace, D.C.1
  • 188
    • 77953507107 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in disease and aging
    • Wallace D.C. Mitochondrial DNA mutations in disease and aging. Environ. Mol. Mutagen. 2010, 51:440-450.
    • (2010) Environ. Mol. Mutagen. , vol.51 , pp. 440-450
    • Wallace, D.C.1
  • 189
    • 0028799005 scopus 로고
    • Structural characterization and regulatory element analysis of the heart isoform of cytochrome c oxidase VIa
    • Wan B., Moreadith R.W. Structural characterization and regulatory element analysis of the heart isoform of cytochrome c oxidase VIa. J. Biol. Chem. 1995, 270:26433-26440.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26433-26440
    • Wan, B.1    Moreadith, R.W.2
  • 190
    • 80053132439 scopus 로고    scopus 로고
    • Increases in mitochondrial biogenesis impair carcinogenesis at multiple levels
    • Wang, X., Moraes, C.T., 2011. Increases in mitochondrial biogenesis impair carcinogenesis at multiple levels. Mol. Oncol. 5 (5), 399-409.
    • (2011) Mol. Oncol. , vol.5 , Issue.5 , pp. 399-409
    • Wang, X.1    Moraes, C.T.2
  • 191
    • 0030744330 scopus 로고    scopus 로고
    • Up-regulation of nuclear genes in response to inhibition of mitochondrial DNA expression in chicken cells
    • Wang H., Morais R. Up-regulation of nuclear genes in response to inhibition of mitochondrial DNA expression in chicken cells. Biochim. Biophys. Acta (BBA) - Gene Struct. Expression 1997, 1352:325-334.
    • (1997) Biochim. Biophys. Acta (BBA) - Gene Struct. Expression , vol.1352 , pp. 325-334
    • Wang, H.1    Morais, R.2
  • 192
    • 15444380906 scopus 로고    scopus 로고
    • The localisation and reduction of nuclear staining of PPARgamma and PGC-1 in human breast cancer
    • Watkins G., Douglas-Jones A., Mansel R.E., Jiang W.G. The localisation and reduction of nuclear staining of PPARgamma and PGC-1 in human breast cancer. Oncol. Rep. 2004, 12:483-488.
    • (2004) Oncol. Rep. , vol.12 , pp. 483-488
    • Watkins, G.1    Douglas-Jones, A.2    Mansel, R.E.3    Jiang, W.G.4
  • 193
    • 77449139468 scopus 로고    scopus 로고
    • PGC-1α activation as a therapeutic approach in mitochondrial disease
    • Wenz T. PGC-1α activation as a therapeutic approach in mitochondrial disease. IUBMB Life 2009, 61:1051-1062.
    • (2009) IUBMB Life , vol.61 , pp. 1051-1062
    • Wenz, T.1
  • 194
    • 84555200221 scopus 로고    scopus 로고
    • Mitochondria and PGC-1α in aging and age-associated diseases
    • Wenz T. Mitochondria and PGC-1α in aging and age-associated diseases. J. Aging Res Volume 2011, 2011. 10.4061/2011/810619 (epub.
    • (2011) J. Aging Res Volume , vol.2011
    • Wenz, T.1
  • 195
    • 80055026172 scopus 로고    scopus 로고
    • A metabolic shift induced by a PPAR panagonist markedly reduces the effects of pathogenic mitochondrial tRNA mutations
    • Wenz T., Wang X., Marini M., Moraes C.T. A metabolic shift induced by a PPAR panagonist markedly reduces the effects of pathogenic mitochondrial tRNA mutations. J Cell Mol Med. 2010.
    • (2010) J Cell Mol Med.
    • Wenz, T.1    Wang, X.2    Marini, M.3    Moraes, C.T.4
  • 198
    • 0014082605 scopus 로고
    • The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver
    • Williamson D.H., Lund P., Krebs H.A. The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem. J. 1967, 103:514-527.
    • (1967) Biochem. J. , vol.103 , pp. 514-527
    • Williamson, D.H.1    Lund, P.2    Krebs, H.A.3
  • 199
    • 79958704151 scopus 로고    scopus 로고
    • NARP mutation and mtDNA depletion trigger mitochondrial biogenesis which can be modulated by selenite supplementation
    • Wojewoda M., Duszynski J., Szczepanowska J. NARP mutation and mtDNA depletion trigger mitochondrial biogenesis which can be modulated by selenite supplementation. Int. J. Biochem. Cell Biol. 2011, 43:1178-1186.
    • (2011) Int. J. Biochem. Cell Biol. , vol.43 , pp. 1178-1186
    • Wojewoda, M.1    Duszynski, J.2    Szczepanowska, J.3
  • 204
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: opposing activities that mediate cell death
    • Youle R.J., Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 2008, 9:47-59.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 206
    • 0035930633 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae multidrug resistance gene expression inversely correlates with the status of the F0 component of the mitochondrial ATPase
    • Zhang X., Moye-Rowley W.S. Saccharomyces cerevisiae multidrug resistance gene expression inversely correlates with the status of the F0 component of the mitochondrial ATPase. J. Biol. Chem. 2001, 276:47844-47852.
    • (2001) J. Biol. Chem. , vol.276 , pp. 47844-47852
    • Zhang, X.1    Moye-Rowley, W.S.2
  • 207
    • 0942279602 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR
    • Zhang Y., Castellani L.W., Sinal C.J., Gonzalez F.J., Edwards P.A. Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR. Genes Dev. 2004, 18:157-169.
    • (2004) Genes Dev. , vol.18 , pp. 157-169
    • Zhang, Y.1    Castellani, L.W.2    Sinal, C.J.3    Gonzalez, F.J.4    Edwards, P.A.5
  • 211
    • 79960560886 scopus 로고    scopus 로고
    • Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1alpha) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis
    • Zhao W., Varghese M., Yemul S., Pan Y., Cheng A., Marano P., Hassan S., Vempati P., Chen F., Qian X., Pasinetti G. Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1alpha) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis. Mol. Neurodegener. 2011, 6:51.
    • (2011) Mol. Neurodegener. , vol.6 , pp. 51
    • Zhao, W.1    Varghese, M.2    Yemul, S.3    Pan, Y.4    Cheng, A.5    Marano, P.6    Hassan, S.7    Vempati, P.8    Chen, F.9    Qian, X.10    Pasinetti, G.11
  • 213
    • 77953807425 scopus 로고    scopus 로고
    • Alterations in the mitochondrial regulatory pathways constituted by the nuclear co-factors PGC-1alpha or PGC-1beta and mitofusin 2 in skeletal muscle in type 2 diabetes
    • Zorzano A., Hernández-Alvarez M.I., Palacín M., Mingrone G. Alterations in the mitochondrial regulatory pathways constituted by the nuclear co-factors PGC-1alpha or PGC-1beta and mitofusin 2 in skeletal muscle in type 2 diabetes. Biochim. Biophys. Acta 2010, 1797(6-7):1028-1033.
    • (2010) Biochim. Biophys. Acta , vol.1797 , Issue.6-7 , pp. 1028-1033
    • Zorzano, A.1    Hernández-Alvarez, M.I.2    Palacín, M.3    Mingrone, G.4


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