MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels

Nature Medicine

Volumn 21, Issue 11, 2015, Pages 1280-1288

  Goedeke, Leigh ^a,b   Rotllan, Noemi ^a   Canfrán Duque, Alberto ^a   Aranda, Juan F ^a,b   Ramírez, Cristina M ^a   Araldi, Elisa ^a,b   Lin, Chin Sheng ^b   Anderson, Norma N ^c   Wagschal, Alexandre ^d,e   De Cabo, Rafael ^f   Horton, Jay D ^c   Lasunción, Miguel A ^g,h   Näär, Anders M ^d,e   Suárez, Yajaira ^a,b   Fernández Hernando, Carlos ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f NATIONAL INSTITUTE ON AGING   (United States)

^g HOSPITAL RAMÓN Y CAJAL   (Spain)

^h Instituto de Salud Carlos III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MICRORNA; MICRORNA 128; MICRORNA 140; MICRORNA 148A; MICRORNA 148B; MICRORNA 193B; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; MIRN148 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IN VIVO STUDY; LIPOPROTEIN METABOLISM; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; HEP-G2 CELL LINE; HIGH THROUGHPUT SCREENING; LIVER; LIVER CELL; METABOLISM; MOUSE; RNA PROCESSING; SIGNAL TRANSDUCTION;

ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; CHOLESTEROL, HDL; CHOLESTEROL, LDL; GENE EXPRESSION REGULATION; HEP G2 CELLS; HEPATOCYTES; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIVER; MICE; MICRORNAS; RECEPTORS, LDL; RNA PROCESSING, POST-TRANSCRIPTIONAL; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84946203425     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3949     Document Type: Article

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