Carborane-containing urea-based inhibitors of glutamate carboxypeptidase II: Synthesis and structural characterization

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 22, 2015, Pages 5232-5236

  Youn, Sihyun ^a   Kim, Kyung Im ^a   Ptacek, Jakub ^b   Ok, Kiwon ^a   Novakova, Zora ^b   Kim, YunHye ^a   Koo, JaeHyung ^c   Barinka, Cyril ^b   Byun, Youngjoo ^a,d  

^a Korea University   (South Korea)

^b INSTITUTE OF BIOTECHNOLOGY   (Czech Republic)

^c Daegu Gyeongbuk Institute of Science and Technology   (South Korea)

^d Korea University College of Medicine   (South Korea)

Author keywords

Carborane; Glutamate carboxypeptidase II; X ray crystal structure

Indexed keywords

CARBORANE DERIVATIVE; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; BORON DERIVATIVE; ENZYME INHIBITOR; UREA;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMISTRY; HUMAN; SYNTHESIS; ULTRASTRUCTURE;

BORON COMPOUNDS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; GLUTAMATE CARBOXYPEPTIDASE II; HUMANS; UREA;

EID: 84945917753     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.09.062     Document Type: Article

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