Development of a high-throughput fluorescence polarization assay to identify novel ligands of glutamate carboxypeptidase II

Journal of Biomolecular Screening

Volumn 17, Issue 8, 2012, Pages 1030-1040

  Alquicer, Glenda ^a   Sedlák, David ^b   Byun, Youngjoo ^c,d   Pavlíček, Jiří ^a   Stathis, Marigo ^e   Rojas, Camilo ^e   Slusher, Barbara ^e   Pomper, Martin G ^c   Bartůněk, Petr ^b   Bařinka, Cyril ^a  

^a INSTITUTE OF BIOTECHNOLOGY   (Czech Republic)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^c DEPARTMENT OF PATHOLOGY   (United States)

^d Korea University   (South Korea)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

fluorescence polarization; glutamate carboxypeptidase II; high throughput screening; metallopeptidase; prostate specific membrane antigen

Indexed keywords

2 (PHOSPHONOMETHYL)PENTANEDIOIC ACID; ARMP 4; DCIBZL; FLUORESCENT DYE; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II INHIBITOR; GLUTAMIC ACID; QUISQUALIC ACID; TMR X LYS UREA GLU; UNCLASSIFIED DRUG;

ARTICLE; DRUG IDENTIFICATION; ENZYME INHIBITION; EVALUATION; FLUORESCENCE POLARIZATION; HIGH THROUGHPUT SCREENING; HUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REPRODUCIBILITY;

ANTIGENS, SURFACE; FLUORESCENCE POLARIZATION; FLUORESCENT DYES; GLUTAMATE CARBOXYPEPTIDASE II; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; PROTEIN BINDING; SMALL MOLECULE LIBRARIES;

EID: 84864997955     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112451924     Document Type: Article

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