A theranostic approach based on the use of a dual boron/Gd agent to improve the efficacy of Boron Neutron Capture Therapy in the lung cancer treatment

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 11, Issue 3, 2015, Pages 741-750

  Alberti, Diego ^a   Protti, Nicoletta ^b,c   Toppino, Antonio ^a   Deagostino, Annamaria ^a   Lanzardo, Stefania ^a   Bortolussi, Silva ^b,c   Altieri, Saverio ^b,c   Voena, Claudia ^a,d   Chiarle, Roberto ^a,d,e   Geninatti Crich, Simonetta ^a   Aime, Silvio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c INFN SEZIONE DI PAVIA   (Italy)

^d CITTÀ DELLA SALUTE E DELLA SCIENZA HOSPITAL   (Italy)

^e BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Boron Neutron Capture Therapy (BNCT); Carboranes; Low density lipoproteins (LDL); MRI; Theranostic agents

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; CELLS; CYTOLOGY; DISEASES; LIPIDS; LIPOPROTEINS; MAGNETIC RESONANCE IMAGING; MAMMALS; NEUTRON IRRADIATION; NEUTRONS; PATHOLOGY; TUMORS;

BORON DISTRIBUTION; BORON NEUTRON CAPTURE THERAPY; BREAST CANCER CELLS; CARBORANES; INTRAVENOUS INJECTIONS; LOW DENSITY LIPOPROTEINS; LUNG METASTASIS; THERANOSTIC AGENTS;

BORON;

AT 101 B 10; LOW DENSITY LIPOPROTEIN; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; BORON; GADOLINIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUGER ELECTRON SPECTROSCOPY; BOLUS INJECTION; BRAIN; BREAST CANCER CELL LINE; CANCER GROWTH; CANCER RADIOTHERAPY; CONTROLLED STUDY; DOSIMETRY; FEMALE; HUMAN; HUMAN CELL; KIDNEY; LIVER; LUNG; LUNG METASTASIS; MOUSE; NEUTRON CAPTURE THERAPY; NEUTRON RADIATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RADIATION DOSE; SMALL INTESTINE; THERMODYNAMICS; TRANSGENIC MOUSE; TUMOR GROWTH; TUMOR VOLUME; ANIMAL; BAGG ALBINO MOUSE; LUNG NEOPLASMS; MAMMARY NEOPLASMS, EXPERIMENTAL; METASTASIS; PATHOLOGY; PROCEDURES;

MUS;

ANIMALS; BORON; BORON NEUTRON CAPTURE THERAPY; FEMALE; GADOLINIUM; LUNG NEOPLASMS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS;

EID: 84933527978     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2014.12.004     Document Type: Article

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