Alpha (α-) and beta (β-carboranyl-C-deoxyribosides: Syntheses, structures and biological evaluation

European Journal of Medicinal Chemistry

Volumn 83, Issue , 2014, Pages 389-397

  Šnajdr, Ivan ^a   Janoušek, Zbyněk ^b   Takagaki, Masao ^c   Císařová, Ivana ^a   Hosmane, Narayan S ^d   Kotora, Martin ^a,b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^c KYOTO UNIVERSITY   (Japan)

^d NORTHERN ILLINOIS UNIVERSITY   (United States)

Author keywords

Alkynes; Antitumor agents; Boron neutron capture therapy; Carboranes; Drug research

Indexed keywords

ALPHA CARBORANYL DEOXYRIBOSIDE; ANTINEOPLASTIC AGENT; BETA CARBORANYL DEOXYRIBOSIDE; DEOXYRIBOSE; UNCLASSIFIED DRUG; BORON DERIVATIVE; NUCLEOSIDE; WATER; 2 (HYDROXYMETHYL) 5 (2 PHENYL DICARBA CLOSO DODECABORAN 1 YL)TETRAHYDRO FURAN 3 OL; 2 (HYDROXYMETHYL) 5 (DICARBA CLOSO DODECABORAN 1 YL)TETRAHYDROFURAN 3 OL; 2 (HYDROXYMETHYL) 5 [2 (2 PHENYL DICARBA CLOSODODECABORAN 1 YL) DICARBA CLOSO DODECABORON 1 YL] TETRAHYDROFURAN 3 OL; 2 (TOLUOYLOXYMETHYL) 3 TOLUOYLOXY 5 (2 PHENYLDICARBA CLOSO DODECABORAN 1 YL)TETRAHYDROFURAN; 2 (TOLUOYLOXYMETHYL) 3 TOLUOYLOXY 5 (DICARBACLOSO DODECABORAN 1 YL)TETRA HYDROFURAN; 2 (TOLUOYLOXYMETHYL) 3 TOLUOYLOXY 5 [2 (2 PHENYLDICARBA CLOSO DODECABO RAN 1 YL) DICARBA CLOSO DODECABORAN 1 YL]TETRAHYDROFURAN; 5 PHENYLETHYNYL 2 (TOLUOYLOXYMETHYL) 3 TOLUOYLOXYTETRAHYDROFURAN; 5 [(4 PHENYLETHYNYL)PHENYLETHYNYL] 2 (TOLUOYLOXYMETHYL) 3 TOLUOYLOXYTETRA HYDROFURAN; 7 [2 [(HYDROXYMETHYL) 3 HYDROXY TETRAHYDROFURAN 5 YL]] 7,8 DICARBA NIDO UNDECARBONATE; CARBORANE DERIVATIVE;

ARTICLE; CYTOTOXICITY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; NEUTRON CAPTURE THERAPY; SQUAMOUS CELL CARCINOMA; X RAY DIFFRACTION; ANIMAL; CHEMISTRY; ISOMERISM; MOUSE; SOLUBILITY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; DRUG CYTOTOXICITY; DRUG SCREENING; NONHUMAN; SQUAMOUS CELL CARCINOMA CELL LINE;

ANIMALS; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; CELL LINE, TUMOR; CHEMISTRY TECHNIQUES, SYNTHETIC; ISOMERISM; MICE; NUCLEOSIDES; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

EID: 84903609015     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.06.005     Document Type: Article

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