Carborane-based carbonic anhydrase inhibitors

Angewandte Chemie - International Edition

Volumn 52, Issue 51, 2013, Pages 13760-13763

  Brynda, Jiří ^a   Mader, Pavel ^a   Šícha, Václav ^c   Fábry, Milan ^a   Poncová, Kristýna ^b   Bakardiev, Mario ^c   Grüner, Bohumír ^c   Cígler, Petr ^b   Řezáčová, Pavlína ^a  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^c INSTITUTE OF INORGANIC CHEMISTRY   (Czech Republic)

Author keywords

carbonic anhydrases; carboranes; drug discovery; inhibitors; structure elucidation

Indexed keywords

CARBONIC ANHYDRASES; CARBORANES; DRUG DISCOVERY; HUMAN CARBONIC ANHYDRASES; SPECIFIC INHIBITORS; STRUCTURE ELUCIDATION; STRUCTURE-BASED DESIGNS; THERAPEUTIC TARGETS;

CHEMICAL REACTIONS; CHEMISTRY; CORROSION INHIBITORS;

CARBONIC ANHYDRASE;

CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR;

ARTICLE; CARBORANES; DRUG DESIGN; DRUG DEVELOPMENT; HUMAN; INHIBITORS; STRUCTURE ACTIVITY RELATION; STRUCTURE ELUCIDATION;

CARBONIC ANHYDRASES; CARBORANES; DRUG DISCOVERY; INHIBITORS; STRUCTURE ELUCIDATION;

CARBONIC ANHYDRASE INHIBITORS; DRUG DESIGN; DRUG DISCOVERY; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84890519855     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201307583     Document Type: Article

References (23)

1. C. T. Supuran, Nat. Rev. Drug Discovery 2008, 7, 168-181.
2. C. T. Supuran, A. Scozzafava, A. Casini, Med. Res. Rev. 2003, 23, 146-189.
3. P. Swietach, S. Patiar, C. T. Supuran, A. L. Harris, R. D. Vaughan-Jones, J. Biol. Chem. 2009, 284, 20299-20310.
4. V. M. Krishnamurthy, G. K. Kaufman, A. R. Urbach, I. Gitlin, K. L. Gudiksen, D. B. Weibel, G. M. Whitesides, Chem. Rev. 2008, 108, 946-1051.
5. M. Aggarwal, R. McKenna, Expert Opin. Ther. Pat. 2012, 22, 903-915.
6. C. T. Supuran, J. Enzyme Inhib. Med. Chem. 2012, 27, 759-772.
7. P. Mader, J. Brynda, R. Gitto, S. Agnello, P. Pachl, C. T. Supuran, A. Chimirri, P. Rezacova, J. Med. Chem. 2011, 54, 2522-2526.
8. R. N. Grimes, Carboranes, 2 nd ed., Academic Press (Elsevier, Inc.), London, 2011, and references therein.
9. Z. J. Lesnikowski, Collect. Czech. Chem. Commun. 2007, 72, 1646-1658.
10. F. Issa, M. Kassiou, L. Rendina, Chem. Rev. 2011, 111, 5701-5722.
11. P. Cigler, M. Kozisek, P. Rezacova, J. Brynda, Z. Otwinowski, J. Pokorna, J. Plesek, B. Gruner, L. Doleckova-Maresova, M. Masa, J. Sedlacek, J. Bodem, H. G. Krausslich, V. Kral, J. Konvalinka, Proc. Natl. Acad. Sci. USA 2005, 102, 15394-15399.
12. Y. Endo, T. Iijima, Y. Yamakoshi, H. Fukasawa, C. Miyaura, M. Inada, A. Kubo, A. Itai, Chem. Biol. 2001, 8, 341-355.
13. S. Fujii, H. Masuno, Y. Taoda, A. Kano, A. Wongmayura, M. Nakabayashi, N. Ito, M. Shimizu, E. Kawachi, T. Hirano, Y. Endo, A. Tanatani, H. Kagechika, J. Am. Chem. Soc. 2011, 133, 20933-20941.
14. M. Scholz, M. Steinhagen, J. T. Heiker, A. G. Beck-Sickinger, E. Hey-Hawkins, ChemMedChem 2011, 6, 89-93.
15. R. C. Reynolds, S. R. Campbell, R. G. Fairchild, R. L. Kisliuk, P. L. Micca, S. F. Queener, J. M. Riordan, W. D. Sedwick, W. R. Waud, A. K. W. Leung, R. W. Dixon, W. J. Suling, D. W. Borhani, J. Med. Chem. 2007, 50, 3283-3289.
16. J. Rak, B. Dejlova, H. Lampova, R. Kaplanek, P. Matejicek, P. Cigler, V. Kral, Mol. Pharm. 2013, 10, 1751-1759.
17. J. G. Wilson, A. K. M. Anisuzzaman, F. Alam, A. H. Soloway, Inorg. Chem. 1992, 31, 1955-1958.
18. J. Plešek, T. Jelínek, E. Drdáková, S. Heřmánek, B. Štíbr, Collect. Czech. Chem. Commun. 1984, 49, 1559-1562.
19. S. L. Woodhouse, L. M. Rendina, J. Chem. Soc. Dalton Trans. 2004, 3669-3677.
20. Y. Wu, P. J. Carroll, S. O. Kang, W. Quintana, Inorg. Chem. 1997, 36, 4753-4761.
21. A. S. Batsanov, A. E. Goeta, J. A. K. Howard, A. K. Hughes, J. M. Malget, J. Chem. Soc. Dalton Trans. 2001, 1820-1826.
22. J. D. Lee, Y. J. Lee, H. J. Jeong, J. S. Lee, C. H. Lee, J. Ko, S. O. Kang, Organometallics 2003, 22, 445-449.
23. P. Řezacova, J. Pokorná, J. Brynda, M. Koží šek, P. Cígler, M. Lepšik, J. Fanfrlík, J. Řezác̈, K. Grantz Šašková, I. Sieglová, J. Plešek, V. Šícha, B. Grüner, H. Oberwinkler, J. Sedláček', H. G. Kräusslich, P. Hobza, V. Král, J. Konvalinka, J. Med. Chem. 2009, 52, 7132-7141.