Structural and functional stabilization of protein entities: State-of-the-art

Advanced Drug Delivery Reviews

Volumn 93, Issue , 2015, Pages 25-41

  Balcão, Victor M ^a,b   Vila, Marta M D C ^a  

^a UNIVERSITY OF SOROCABA   (Brazil)

^b UNIVERSITY OF MINHO   (Portugal)

Author keywords

Bacteriophages; Biopharmaceutical applications; Immobilization and post immobilization; Protein stability; Structural and functional stabilization

Indexed keywords

ANTIBODIES; BACTERIOPHAGES; BIOMOLECULES; MOLECULES; RECOMBINANT PROTEINS;

HYDROPHILIC POLYMERS; MULTIPOINT COVALENT ATTACHMENTS; PHARMACEUTICAL SCIENCE; PROTEIN STABILITY; PROTEIN STABILIZATION; STRUCTURAL TRANSITIONS; THERAPEUTIC MOLECULES; THERMODYNAMIC EQUILIBRIA;

STABILIZATION;

DIMETHYL SULFOXIDE; GLYCEROL; MACROGOL; MONOCLONAL ANTIBODY; NANOCAPSULE; NANOCARRIER; POLYMER; PROTEIN; RECOMBINANT PROTEIN; SODIUM CHLORIDE; SUGAR;

ADSORPTION; BACTERIOPHAGE; CHEMICAL BINDING; CONJUGATION; COVALENT BOND; CROSS LINKING; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; MOLECULAR STABILITY; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE; REVIEW; THERMODYNAMICS; THERMOSTABILITY; CHEMICAL PHENOMENA; CHEMISTRY; DRUG DELIVERY SYSTEM; HUMAN; MEDICINAL CHEMISTRY; PROCEDURES;

ANTIBODIES, MONOCLONAL; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; DRUG STORAGE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; POLYMERS; PROTEIN STABILITY; PROTEINS; RECOMBINANT PROTEINS; THERMODYNAMICS;

EID: 84945468241     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2014.10.005     Document Type: Review

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