MicroRNA-146a induced by hypoxia promotes chondrocyte autophagy through Bcl-2

Cellular Physiology and Biochemistry

Volumn 37, Issue 4, 2015, Pages 1442-1453

  Zhang, Fei ^a   Wang, Jing ^b   Chu, Jianjun ^c   Yang, Cheng ^b   Xiao, Hui ^b   Zhao, Chenglong ^b   Sun, Zhengwang ^b   Gao, Xin ^b   Chen, Guanghui ^b   Han, Zhitao ^b   Zou, Weiwei ^b   Liu, Tielong ^b  

^a Oncology and Hematology Department   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c Binhu Hospital   (China)

Author keywords

Autophagy; Cartilage; HIF 1; MiR 146a; Osteoarthritis (OA)

Indexed keywords

AGGRECANASE 2; AUTOPHAGY PROTEIN 5; COLLAGENASE 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA 132; MICRORNA 146A; MICRORNA 16; PROTEIN; PROTEIN BCL 2; TRANSCRIPTION FACTOR SOX9; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; ULK 1 PROTEIN; UNCLASSIFIED DRUG; ANTISENSE OLIGONUCLEOTIDE; ATG5 PROTEIN, MOUSE; MAP1LC3 PROTEIN, MOUSE; MICRORNA; MICROTUBULE ASSOCIATED PROTEIN; MIRN146 MICRORNA, MOUSE; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; ULK1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; AUTOPHAGY; CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CONTROLLED STUDY; GENE EXPRESSION; HYPOXIA; MOUSE; NONHUMAN; OSTEOARTHRITIS; OXYGEN TENSION; PATHOGENESIS; PRIORITY JOURNAL; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL HYPOXIA; CYTOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; RNA INTERFERENCE;

ANIMALS; AUTOPHAGY; CARTILAGE, ARTICULAR; CELL HYPOXIA; CELLS, CULTURED; CHONDROCYTES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICRORNAS; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84945132432     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000438513     Document Type: Article

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