Protocadherin 17 acts as a tumour suppressor inducing tumour cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers

Journal of Pathology

Volumn 229, Issue 1, 2013, Pages 62-73

  Hu, Xiaotong ^a   Sui, Xinbing ^a   Li, Lili ^b,c   Huang, Xuefeng ^a   Rong, Rong ^b,c   Su, Xianwei ^b,c   Shi, Qinglan ^a   Mo, Lijuan ^a   Shu, Xingsheng ^b,c   Kuang, Yeye ^a   Tao, Qian ^b,c   He, Chao ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

apoptosis; autophagy; methylation; PCDH17; tumour suppressor gene

Indexed keywords

AUTOPHAGY PROTEIN 12; AUTOPHAGY PROTEIN 5; CADHERIN; CASPASE 3; FLUOROURACIL; PEPTIDES AND PROTEINS; PROTOCADHERIN 17; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CANCER INHIBITION; CANCER STAGING; CARCINOGENESIS; CELL VIABILITY; COLON MUCOSA; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; METHYLATION; MOUSE; MUTATION; NICK END LABELING; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CANCER; STOMACH MUCOSA; TUMOR CELL; UPREGULATION;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; AUTOPHAGY; CADHERINS; CASPASE 3; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DNA METHYLATION; DOWN-REGULATION; FEMALE; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HCT116 CELLS; HUMANS; IN SITU NICK-END LABELING; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; PROMOTER REGIONS, GENETIC; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; STOMACH NEOPLASMS; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 84872860185     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4093     Document Type: Article

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