Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 37134-37144

  Aro, Ellinoora ^a   Khatri, Richa ^b   Gerard O'Riley, Rita ^b   Mangiavini, Laura ^b   Myllyharju, Johanna ^a   Schipani, Ernestina ^b  

^a UNIVERSITY OF OULU   (Finland)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROCYTES; EXTRACELLULAR MATRICES; GROWTH PLATE; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIC INDUCTION; KEY ENZYMES; NEWBORN MICE;

COLLAGEN;

BODY FLUIDS;

COLLAGEN; COLLAGEN PROPLYL 4 HYDROXYLASE 1; COLLAGEN PROPLYL 4 HYDROXYLASE 2; COLLAGEN PROPLYL 4 HYDROXYLASE 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; ISOENZYME; MESSENGER RNA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE; TETRAMER; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

ANIMAL CELL; ARTICLE; C P4H GENE; CARTILAGE CELL; CELL HYPOXIA; CELL ISOLATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; EPIPHYSIS PLATE; FETUS GROWTH; GROWTH PLATE; HYDROXYLATION; MOUSE; NEWBORN; NONHUMAN; P4HA1 GENE; P4HA2 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION;

ANIMALS; ANIMALS, NEWBORN; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL HYPOXIA; CELLS, CULTURED; CHONDROCYTES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; GROWTH PLATE; HUMANS; HYDROXYPROLINE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; PRIMARY CELL CULTURE; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN MULTIMERIZATION; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84868217190     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.352872     Document Type: Article

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