Bridging scales through multiscale modeling: A case study on protein kinase A

Frontiers in Physiology

Volumn 6, Issue SEP, 2015, Pages

  Boras, Britton W ^a   Hirakis, Sophia P ^b   Votapka, Lane W ^b   Malmstrom, Robert D ^b   Amaro, Rommie E ^b   McCulloch, Andrew D ^a,b,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Brownian dynamics; Markov state model; Molecular dynamics; Multiscale model; Protein kinase A

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC NUCLEOTIDE;

ADRENERGIC SYSTEM; ASSOCIATION RATE CONSTANT; BROWNIAN DYNAMICS; HEART ARRHYTHMIA; HUMAN; MARKOV STATE MODEL; MATHEMATICAL COMPUTING; MOLECULAR CROWDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; PHYSICOCHEMICAL MODEL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; REVIEW; STOCHASTIC MODEL; WHOLE CELL;

EID: 84944715410     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2015.00250     Document Type: Review

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