Modeling β-Adrenergic Control of Cardiac Myocyte Contractility in Silico

Journal of Biological Chemistry

Volumn 278, Issue 48, 2003, Pages 47997-48003

  Saucerman, Jeffrey J ^a   Brunton, Laurence L ^b   Michailova, Anushka P ^a,c   McCulloch, Andrew D ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; PERTURBATION TECHNIQUES; PHYSIOLOGY; PROTEINS; SHRINKAGE; SIGNALING; TOPOLOGY;

PHOSPHORYLATION;

BIOCHEMISTRY;

ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR; CALCIUM CHANNEL L TYPE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; NEUROHORMONE; PHOSPHOLAMBAN; PROTEIN KINASE INHIBITOR;

ADRENERGIC SYSTEM; ARTICLE; CELL FUNCTION; COMPUTER MODEL; ENZYME ACTIVATION; EXCITATION CONTRACTION COUPLING; FEEDBACK SYSTEM; GENE OVEREXPRESSION; HEART MUSCLE CONTRACTILITY; INOTROPISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; THERMOSTABILITY;

NASA DISCIPLINE CARDIOPULMONARY; NASA PROGRAM BIOMEDICAL RESEARCH AND COUNTERMEASURES; NON-NASA CENTER;

ADENYLATE CYCLASE; ANIMALS; CALCIUM CHANNELS, L-TYPE; CALCIUM-BINDING PROTEINS; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; ISOPROTERENOL; KINETICS; MARKOV CHAINS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, THEORETICAL; MYOCARDIUM; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION; SYSTEMS ANALYSIS; TIME FACTORS;

EID: 0346850834     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M308362200     Document Type: Article

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