Markov modeling of ion channels: Implications for understanding disease

Progress in Molecular Biology and Translational Science

Volumn 123, Issue , 2014, Pages 1-21

  Lampert, Angelika ^a,b   Korngreen, Alon ^c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c BAR ILAN UNIVERSITY   (Israel)

Author keywords

Action potential; Ion channel; Kinetic model; Markov chain; Model; Optimisation; Pain; Sodium channel; Voltage clamp; Voltage gated

Indexed keywords

SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.3; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.6; SODIUM CHANNEL NAV1.7; SODIUM CHANNEL NAV1.8; SODIUM CHANNEL NAV1.9; VOLTAGE GATED SODIUM CHANNEL; ION CHANNEL;

ARTICLE; CELL STRUCTURE; CHANNELOPATHY; COMPUTER MODEL; CONFORMATIONAL TRANSITION; ELECTROPHYSIOLOGICAL PROCEDURES; EPILEPSY; ERYTHROMELALGIA; HUMAN; LOSS OF FUNCTION MUTATION; MARKOV MODEL; MEMBRANE POTENTIAL; NERVE CELL EXCITABILITY; PAIN; PATHOPHYSIOLOGY; PROTEIN FUNCTION; PROTEIN STRUCTURE; VOLTAGE CLAMP TECHNIQUE; WHOLE CELL PATCH CLAMP; ANIMAL; BIOLOGICAL MODEL; DISEASES; METABOLISM; PATCH CLAMP TECHNIQUE; PROBABILITY;

ANIMALS; DISEASE; HUMANS; ION CHANNELS; MARKOV CHAINS; MODELS, NEUROLOGICAL; PATCH-CLAMP TECHNIQUES;

EID: 84896725831     PISSN: 18771173     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-397897-400009-7     Document Type: Article

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