-
1
-
-
17144380822
-
The metabolic syndrome
-
COI: 1:CAS:528:DC%2BD2MXjsVegtbg%3D
-
Eckel RH, Grundy SM, Zimmet PZ (2005) The metabolic syndrome. Lancet 365:1415–1428
-
(2005)
Lancet
, vol.365
, pp. 1415-1428
-
-
Eckel, R.H.1
Grundy, S.M.2
Zimmet, P.Z.3
-
2
-
-
75449094816
-
Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications
-
COI: 1:CAS:528:DC%2BC3cXisVGnsrk%3D
-
Fabbrini E, Sullivan S, Klein S (2010) Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology 51:679–689
-
(2010)
Hepatology
, vol.51
, pp. 679-689
-
-
Fabbrini, E.1
Sullivan, S.2
Klein, S.3
-
3
-
-
33644850953
-
Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss
-
Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, Eckel RH (2006) Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss. Circulation 113:898–918
-
(2006)
Circulation
, vol.113
, pp. 898-918
-
-
Poirier, P.1
Giles, T.D.2
Bray, G.A.3
Hong, Y.4
Stern, J.S.5
Pi-Sunyer, F.X.6
Eckel, R.H.7
-
4
-
-
80051668515
-
Obesity, blood vessels and metabolic syndrome
-
COI: 1:CAS:528:DC%2BC3MXhtFeqtrjN
-
Tesauro M, Cardillo C (2011) Obesity, blood vessels and metabolic syndrome. Acta Physiol (Oxf) 203:279–286
-
(2011)
Acta Physiol (Oxf)
, vol.203
, pp. 279-286
-
-
Tesauro, M.1
Cardillo, C.2
-
5
-
-
84865496465
-
Obesity and metabolic syndrome as related to cardiovascular disease
-
COI: 1:CAS:528:DC%2BC38Xht1altb%2FK
-
Nikolopoulou A, Kadoglou NP (2012) Obesity and metabolic syndrome as related to cardiovascular disease. Expert Rev Cardiovasc Ther 10:933–939
-
(2012)
Expert Rev Cardiovasc Ther
, vol.10
, pp. 933-939
-
-
Nikolopoulou, A.1
Kadoglou, N.P.2
-
6
-
-
79551618139
-
The association of left ventricular hypertrophy with metabolic syndrome is dependent on body mass index in hypertensive overweight or obese patients
-
COI: 1:CAS:528:DC%2BC3MXhvFahtbk%3D
-
Guerra F, Mancinelli L, Angelini L, Fortunati M, Rappelli A, Dessì-Fulgheri P, Sarzani R (2011) The association of left ventricular hypertrophy with metabolic syndrome is dependent on body mass index in hypertensive overweight or obese patients. PLoS One 6:e16630
-
(2011)
PLoS One
, vol.6
-
-
Guerra, F.1
Mancinelli, L.2
Angelini, L.3
Fortunati, M.4
Rappelli, A.5
Dessì-Fulgheri, P.6
Sarzani, R.7
-
7
-
-
50549091935
-
Management of dyslipidaemia—evidence and practical recommendations
-
Nestel PJ, O’Brien R, Nelson M (2008) Management of dyslipidaemia—evidence and practical recommendations. Aust Fam Physician 37:521–527
-
(2008)
Aust Fam Physician
, vol.37
, pp. 521-527
-
-
Nestel, P.J.1
O’Brien, R.2
Nelson, M.3
-
8
-
-
84862863619
-
Obesity and metabolic syndrome: an inflammatory condition
-
COI: 1:STN:280:DC%2BC38jjvFalsA%3D%3D
-
Scarpellini E, Tack J (2012) Obesity and metabolic syndrome: an inflammatory condition. Dig Dis 30:148–153
-
(2012)
Dig Dis
, vol.30
, pp. 148-153
-
-
Scarpellini, E.1
Tack, J.2
-
9
-
-
79953046341
-
Inflammatory mechanisms in obesity
-
COI: 1:CAS:528:DC%2BC3MXltlKnsL8%3D
-
Gregor MF, Hotamisligil GS (2011) Inflammatory mechanisms in obesity. Annu Rev Immunol 29:415–445
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 415-445
-
-
Gregor, M.F.1
Hotamisligil, G.S.2
-
10
-
-
84919882696
-
Oxidative stress in obesity: a critical component in human diseases
-
Marseglia L, Manti S, D’Angelo G, Nicotera A, Parisi E, Di Rosa G, Gitto E, Arrigo T (2015) Oxidative stress in obesity: a critical component in human diseases. Int J Mol Sci 16:378–400
-
(2015)
Int J Mol Sci
, vol.16
, pp. 378-400
-
-
Marseglia, L.1
Manti, S.2
D’Angelo, G.3
Nicotera, A.4
Parisi, E.5
Di Rosa, G.6
Gitto, E.7
Arrigo, T.8
-
12
-
-
85011424911
-
-
National Heart Foundation of Australia. Factsheet: overweight and obesity statistics 2012
-
National Heart Foundation of Australia. Factsheet: overweight and obesity statistics 2012
-
-
-
-
13
-
-
85011332231
-
Adult anthropometric measures
-
Health Survey of England. Adult anthropometric measures, overweight and obesity 2013
-
(2013)
Overweight and obesity
-
-
-
14
-
-
77952772854
-
Trends in overweight and obese adults in Malaysia (1996–2009): a systematic review
-
COI: 1:STN:280:DC%2BC3cnjslGruw%3D%3D
-
Khambalia AZ, Seen LS (2010) Trends in overweight and obese adults in Malaysia (1996–2009): a systematic review. Obes Rev 11:403–412
-
(2010)
Obes Rev
, vol.11
, pp. 403-412
-
-
Khambalia, A.Z.1
Seen, L.S.2
-
15
-
-
80052230235
-
Nutrapharmacology of tocotrienols for metabolic syndrome
-
Weng-Yew W, Brown L (2011) Nutrapharmacology of tocotrienols for metabolic syndrome. Curr Pharm Des 17:2206–2214
-
(2011)
Curr Pharm Des
, vol.17
, pp. 2206-2214
-
-
Weng-Yew, W.1
Brown, L.2
-
16
-
-
84868139301
-
Tocotrienols reverse cardiovascular, metabolic and liver changes in high carbohydrate, high fat diet-fed rats
-
COI: 1:CAS:528:DC%2BC38XhvVagsr%2FN
-
Wong WY, Poudyal H, Ward LC, Brown L (2012) Tocotrienols reverse cardiovascular, metabolic and liver changes in high carbohydrate, high fat diet-fed rats. Nutrients 4:1527–1541
-
(2012)
Nutrients
, vol.4
, pp. 1527-1541
-
-
Wong, W.Y.1
Poudyal, H.2
Ward, L.C.3
Brown, L.4
-
17
-
-
34249868200
-
Vitamin E, antioxidant and nothing more
-
COI: 1:CAS:528:DC%2BD2sXmtlagtb0%3D
-
Traber MG, Atkinson J (2007) Vitamin E, antioxidant and nothing more. Free Radic Biol Med 43:4–15
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 4-15
-
-
Traber, M.G.1
Atkinson, J.2
-
18
-
-
0037336266
-
Comparative study on the action of tocopherols and tocotrienols as antioxidant: chemical and physical effects
-
COI: 1:CAS:528:DC%2BD3sXhvFWqt7Y%3D
-
Yoshida Y, Niki E, Noguchi N (2003) Comparative study on the action of tocopherols and tocotrienols as antioxidant: chemical and physical effects. Chem Phys Lipids 123:63–75
-
(2003)
Chem Phys Lipids
, vol.123
, pp. 63-75
-
-
Yoshida, Y.1
Niki, E.2
Noguchi, N.3
-
19
-
-
77957909450
-
Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases
-
COI: 1:CAS:528:DC%2BC3cXhtlSmsbnE
-
Aggarwal BB, Sundaram C, Prasad S, Kannappan R (2010) Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases. Biochem Pharmacol 80:1613–1631
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 1613-1631
-
-
Aggarwal, B.B.1
Sundaram, C.2
Prasad, S.3
Kannappan, R.4
-
20
-
-
79958211266
-
Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats
-
COI: 1:CAS:528:DC%2BC3MXmvFeht7s%3D
-
Panchal SK, Poudyal H, Arumugam TV, Brown L (2011) Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats. J Nutr 141:1062–1069
-
(2011)
J Nutr
, vol.141
, pp. 1062-1069
-
-
Panchal, S.K.1
Poudyal, H.2
Arumugam, T.V.3
Brown, L.4
-
21
-
-
0036374477
-
Guidelines for the design and statistical analysis of experiments using laboratory animals
-
COI: 1:CAS:528:DC%2BD38Xnt1SitLk%3D
-
Festing MFW, Altman DG (2002) Guidelines for the design and statistical analysis of experiments using laboratory animals. ILAR J 43:244–258
-
(2002)
ILAR J
, vol.43
, pp. 244-258
-
-
Festing, M.F.W.1
Altman, D.G.2
-
23
-
-
0034969060
-
Oral toxicity of a tocotrienol preparation in rats
-
COI: 1:CAS:528:DC%2BD3MXkvVeitrc%3D
-
Nakamura H, Furukawa F, Nishikawa A, Miyauchi M, Son HY, Imazawa T, Hirose M (2001) Oral toxicity of a tocotrienol preparation in rats. Food Chem Toxicol 39:799–805
-
(2001)
Food Chem Toxicol
, vol.39
, pp. 799-805
-
-
Nakamura, H.1
Furukawa, F.2
Nishikawa, A.3
Miyauchi, M.4
Son, H.Y.5
Imazawa, T.6
Hirose, M.7
-
24
-
-
0036928514
-
Echocardiographic assessment of cardiac structure and function in rats
-
Brown L, Fenning A, Chan V, Loch D, Wilson K, Anderson B, Burstow D (2002) Echocardiographic assessment of cardiac structure and function in rats. Heart Lung Circ 11:167–173
-
(2002)
Heart Lung Circ
, vol.11
, pp. 167-173
-
-
Brown, L.1
Fenning, A.2
Chan, V.3
Loch, D.4
Wilson, K.5
Anderson, B.6
Burstow, D.7
-
25
-
-
77953716487
-
Assessment of body composition of rats by bioimpedance spectroscopy validation against dual-energy X-ray absorptiometry
-
COI: 1:CAS:528:DC%2BC3cXisVCit74%3D
-
Ward LC, Battersby KJ (2009) Assessment of body composition of rats by bioimpedance spectroscopy validation against dual-energy X-ray absorptiometry. Scand J Lab Anim Sci 36:253–261
-
(2009)
Scand J Lab Anim Sci
, vol.36
, pp. 253-261
-
-
Ward, L.C.1
Battersby, K.J.2
-
26
-
-
33746846631
-
Chronic dietary vitamin A supplementation regulates obesity in an obese mutant WNIN/Ob rat model
-
COI: 1:CAS:528:DC%2BD28XjvFWjsr8%3D
-
Jeyakumar SM, Vajreswari A, Giridharan NV (2006) Chronic dietary vitamin A supplementation regulates obesity in an obese mutant WNIN/Ob rat model. Obesity 14:52–59
-
(2006)
Obesity
, vol.14
, pp. 52-59
-
-
Jeyakumar, S.M.1
Vajreswari, A.2
Giridharan, N.V.3
-
27
-
-
33749326981
-
Improved cardiovascular function with aminoguanidine in DOCA-salt hypertensive rats
-
COI: 1:CAS:528:DC%2BD28XnsFWrur4%3D
-
Chan V, Hoey A, Brown L (2006) Improved cardiovascular function with aminoguanidine in DOCA-salt hypertensive rats. Br J Pharmacol 148:902–908
-
(2006)
Br J Pharmacol
, vol.148
, pp. 902-908
-
-
Chan, V.1
Hoey, A.2
Brown, L.3
-
28
-
-
33846876720
-
Isolated heart perfusion according to Langendorff—still viable in the new millennium
-
COI: 1:CAS:528:DC%2BD2sXhvVyhsrg%3D
-
Skrzypiec-Spring M, Grotthus B, Szelag A, Schulz R (2007) Isolated heart perfusion according to Langendorff—still viable in the new millennium. J Pharmacol Toxicol Methods 55:113–126
-
(2007)
J Pharmacol Toxicol Methods
, vol.55
, pp. 113-126
-
-
Skrzypiec-Spring, M.1
Grotthus, B.2
Szelag, A.3
Schulz, R.4
-
29
-
-
0032951864
-
Reversal of cardiac fibrosis in deoxycorticosterone acetate-salt hypertensive rats by inhibition of the renin-angiotensin system
-
COI: 1:CAS:528:DyaK1MXmvFSnsg%3D%3D
-
Brown L, Duce B, Miric G, Sernia C (1999) Reversal of cardiac fibrosis in deoxycorticosterone acetate-salt hypertensive rats by inhibition of the renin-angiotensin system. J Am Soc Nephrol 10(Suppl 11):S143–S148
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. S143-S148
-
-
Brown, L.1
Duce, B.2
Miric, G.3
Sernia, C.4
-
31
-
-
0023217965
-
New solvent system for extraction of tocopherols from biological specimens for HPLC determination and evaluation of 2,2,5,7,8-pentamethyl-6-chromanol as an internal standard
-
COI: 1:CAS:528:DyaL2sXlslWktb8%3D
-
Ueda T, Igarashi O (1987) New solvent system for extraction of tocopherols from biological specimens for HPLC determination and evaluation of 2,2,5,7,8-pentamethyl-6-chromanol as an internal standard. J Micronutr Anal 3:185–198
-
(1987)
J Micronutr Anal
, vol.3
, pp. 185-198
-
-
Ueda, T.1
Igarashi, O.2
-
32
-
-
38149070320
-
Vitamin E revisited: do new data validate benefits for chronic disease prevention?
-
COI: 1:CAS:528:DC%2BD1cXmt1ynug%3D%3D
-
Traber MG, Frei B, Beckman JS (2008) Vitamin E revisited: do new data validate benefits for chronic disease prevention? Curr Opin Lipidol 19:30–38
-
(2008)
Curr Opin Lipidol
, vol.19
, pp. 30-38
-
-
Traber, M.G.1
Frei, B.2
Beckman, J.S.3
-
33
-
-
84874492074
-
Cancer prevention by different forms of tocopherols
-
Pezzuto JM, Suh N, (eds), Springer, Berlin
-
Yang C, Suh N (2013) Cancer prevention by different forms of tocopherols. In: Pezzuto JM, Suh N (eds) Natural products in cancer prevention and therapy. Springer, Berlin, pp 21–33
-
(2013)
Natural products in cancer prevention and therapy
, pp. 21-33
-
-
Yang, C.1
Suh, N.2
-
35
-
-
0030015296
-
The chemistry and antioxidant properties of tocopherols and tocotrienols
-
COI: 1:CAS:528:DyaK28XktlKkt74%3D
-
Kamal-Eldin A, Appelqvist L-Å (1996) The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31:671–701
-
(1996)
Lipids
, vol.31
, pp. 671-701
-
-
Kamal-Eldin, A.1
Appelqvist, L.-Å.2
-
36
-
-
77951968716
-
Mechanisms of obesity-induced hypertension
-
Kotsis V, Stabouli S, Papakatsika S, Rizos Z, Parati G (2010) Mechanisms of obesity-induced hypertension. Hypertens Res 33:386–393
-
(2010)
Hypertens Res
, vol.33
, pp. 386-393
-
-
Kotsis, V.1
Stabouli, S.2
Papakatsika, S.3
Rizos, Z.4
Parati, G.5
-
37
-
-
77955983169
-
Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults
-
COI: 1:CAS:528:DC%2BC3cXhtVCntrvM
-
Lambert E, Sari CI, Dawood T, Nguyen J, McGrane M, Eikelis N, Chopra R, Wong C, Chatzivlastou K, Head G, Straznicky N, Esler M, Schlaich M, Lambert G (2010) Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults. Hypertension 56:351–358
-
(2010)
Hypertension
, vol.56
, pp. 351-358
-
-
Lambert, E.1
Sari, C.I.2
Dawood, T.3
Nguyen, J.4
McGrane, M.5
Eikelis, N.6
Chopra, R.7
Wong, C.8
Chatzivlastou, K.9
Head, G.10
Straznicky, N.11
Esler, M.12
Schlaich, M.13
Lambert, G.14
-
38
-
-
0031736312
-
Interactions between the renin-angiotensin system (RAS) and the sympathetic system
-
COI: 1:CAS:528:DyaK1cXntlWrtLw%3D
-
Dendorfer A, Raasch W, Tempel K, Dominiak P (1998) Interactions between the renin-angiotensin system (RAS) and the sympathetic system. Basic Res Cardiol 93:24–29
-
(1998)
Basic Res Cardiol
, vol.93
, pp. 24-29
-
-
Dendorfer, A.1
Raasch, W.2
Tempel, K.3
Dominiak, P.4
-
39
-
-
63549127625
-
Circulating adrenaline released by sympathoadrenal activation elicits acute vasodilatation in the rat masseter muscle
-
COI: 1:CAS:528:DC%2BD1MXksVaiu7g%3D
-
Ishii H, Niioka T, Izumi H (2009) Circulating adrenaline released by sympathoadrenal activation elicits acute vasodilatation in the rat masseter muscle. Arch Oral Biol 54:486–494
-
(2009)
Arch Oral Biol
, vol.54
, pp. 486-494
-
-
Ishii, H.1
Niioka, T.2
Izumi, H.3
-
40
-
-
81155158871
-
Sympathetic nervous dysregulation in the absence of systolic left ventricular dysfunction in a rat model of insulin resistance with hyperglycemia
-
COI: 1:CAS:528:DC%2BC3MXhtFyhsbjM
-
Thackeray JT, Radziuk J, Harper ME, Suuronen EJ, Ascah KJ, Beanlands RS, Dasilva JN (2011) Sympathetic nervous dysregulation in the absence of systolic left ventricular dysfunction in a rat model of insulin resistance with hyperglycemia. Cardiovasc Diabetol 10:75
-
(2011)
Cardiovasc Diabetol
, vol.10
, pp. 75
-
-
Thackeray, J.T.1
Radziuk, J.2
Harper, M.E.3
Suuronen, E.J.4
Ascah, K.J.5
Beanlands, R.S.6
Dasilva, J.N.7
-
41
-
-
0034988490
-
Chronic administration of pharmacologic doses of vitamin E improves the cardiac autonomic nervous system in patients with type 2 diabetes
-
COI: 1:CAS:528:DC%2BD3MXktlWhsr8%3D
-
Manzella D, Barbieri M, Ragno E, Paolisso G (2001) Chronic administration of pharmacologic doses of vitamin E improves the cardiac autonomic nervous system in patients with type 2 diabetes. Am J Clin Nutr 73:1052–1057
-
(2001)
Am J Clin Nutr
, vol.73
, pp. 1052-1057
-
-
Manzella, D.1
Barbieri, M.2
Ragno, E.3
Paolisso, G.4
-
42
-
-
61449256036
-
Tocotrienol and a-tocopherol reduce corticosterone and noradrenalin levels in rats exposed to restraint stress
-
COI: 1:STN:280:DC%2BD1M7gsVyqtw%3D%3D
-
Nur Azlina MF, Nafeeza MI (2008) Tocotrienol and a-tocopherol reduce corticosterone and noradrenalin levels in rats exposed to restraint stress. Pharmazie 63:890–892
-
(2008)
Pharmazie
, vol.63
, pp. 890-892
-
-
Nur Azlina, M.F.1
Nafeeza, M.I.2
-
43
-
-
24344501293
-
Tocotrienols reverse IKAP and monoamine oxidase deficiencies in familial dysautonomia
-
COI: 1:CAS:528:DC%2BD2MXpvFeitbc%3D
-
Anderson SL, Rubin BY (2005) Tocotrienols reverse IKAP and monoamine oxidase deficiencies in familial dysautonomia. Biochem Biophys Res Commun 336:150–156
-
(2005)
Biochem Biophys Res Commun
, vol.336
, pp. 150-156
-
-
Anderson, S.L.1
Rubin, B.Y.2
-
44
-
-
1842476274
-
Effects of tocopherols and tocotrienols on body composition and bone calcium content in adrenalectomized rats replaced with dexamethasone
-
COI: 1:CAS:528:DC%2BD2cXjtV2lsrk%3D
-
Ima-Nirwana S, Suhaniza S (2004) Effects of tocopherols and tocotrienols on body composition and bone calcium content in adrenalectomized rats replaced with dexamethasone. J Med Food 7:45–51
-
(2004)
J Med Food
, vol.7
, pp. 45-51
-
-
Ima-Nirwana, S.1
Suhaniza, S.2
-
45
-
-
84863469831
-
Tocotrienol attenuates triglyceride accumulation in HepG2 Cells and F344 rats
-
COI: 1:CAS:528:DC%2BC38XivVSjtrc%3D
-
Burdeos G, Nakagawa K, Kimura F, Miyazawa T (2012) Tocotrienol attenuates triglyceride accumulation in HepG2 Cells and F344 rats. Lipids 47:471–481
-
(2012)
Lipids
, vol.47
, pp. 471-481
-
-
Burdeos, G.1
Nakagawa, K.2
Kimura, F.3
Miyazawa, T.4
-
46
-
-
58649087808
-
Tocotrienol suppresses adipocyte differentiation and Akt phosphorylation in 3T3-L1 preadipocytes
-
COI: 1:CAS:528:DC%2BD1cXhsFCqsbvF
-
Uto-Kondo H, Ohmori R, Kiyose C, Kishimoto Y, Saito H, Igarashi O, Kondo K (2009) Tocotrienol suppresses adipocyte differentiation and Akt phosphorylation in 3T3-L1 preadipocytes. J Nutr 139:51–57
-
(2009)
J Nutr
, vol.139
, pp. 51-57
-
-
Uto-Kondo, H.1
Ohmori, R.2
Kiyose, C.3
Kishimoto, Y.4
Saito, H.5
Igarashi, O.6
Kondo, K.7
-
47
-
-
79952624643
-
Unleashing the untold and misunderstood observations on vitamin E
-
Gee P (2010) Unleashing the untold and misunderstood observations on vitamin E. Genes Nutr 6:5–16
-
(2010)
Genes Nutr
, vol.6
, pp. 5-16
-
-
Gee, P.1
-
48
-
-
0029863624
-
Lymphatic transport of alpha-, gamma- and delta-tocotrienols and alpha-tocopherol in rats
-
COI: 1:CAS:528:DyaK28XmsFertbk%3D
-
Ikeda I, Imasato Y, Sasaki E, Sugano M (1996) Lymphatic transport of alpha-, gamma- and delta-tocotrienols and alpha-tocopherol in rats. Int J Vitam Nutr Res 66:217–221
-
(1996)
Int J Vitam Nutr Res
, vol.66
, pp. 217-221
-
-
Ikeda, I.1
Imasato, Y.2
Sasaki, E.3
Sugano, M.4
-
49
-
-
31344447948
-
The metabolic syndrome: inflammation, diabetes mellitus, and cardiovascular disease
-
Haffner SM (2006) The metabolic syndrome: inflammation, diabetes mellitus, and cardiovascular disease. Am J Cardiol 97:3–11
-
(2006)
Am J Cardiol
, vol.97
, pp. 3-11
-
-
Haffner, S.M.1
-
50
-
-
65249119361
-
Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation
-
COI: 1:CAS:528:DC%2BD1MXisV2jsLo%3D
-
Shimizu T (2009) Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation. Annu Rev Pharmacol Toxicol 49:123–150
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 123-150
-
-
Shimizu, T.1
-
51
-
-
76149111947
-
Inflammatory lipid mediators in adipocyte function and obesity
-
COI: 1:CAS:528:DC%2BC3cXpslCqsQ%3D%3D
-
Iyer A, Fairlie DP, Prins JB, Hammock BD, Brown L (2010) Inflammatory lipid mediators in adipocyte function and obesity. Nat Rev Endocrinol 6:71–82
-
(2010)
Nat Rev Endocrinol
, vol.6
, pp. 71-82
-
-
Iyer, A.1
Fairlie, D.P.2
Prins, J.B.3
Hammock, B.D.4
Brown, L.5
-
52
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
COI: 1:CAS:528:DC%2BD3cXkvFWhu7k%3D
-
Shulman GI (2000) Cellular mechanisms of insulin resistance. J Clin Invest 106:171–176
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
53
-
-
0035487317
-
Intramyocellular lipid is associated with resistance to in vivo insulin actions on glucose uptake, antilipolysis, and early insulin signaling pathways in human skeletal muscle
-
COI: 1:CAS:528:DC%2BD3MXntlGhu7k%3D
-
Virkamaki A, Korsheninnikova E, Seppala-Lindroos A, Vehkavaara S, Goto T, Halavaara J, Hakkinen AM, Yki-Jarvinen H (2001) Intramyocellular lipid is associated with resistance to in vivo insulin actions on glucose uptake, antilipolysis, and early insulin signaling pathways in human skeletal muscle. Diabetes 50:2337–2343
-
(2001)
Diabetes
, vol.50
, pp. 2337-2343
-
-
Virkamaki, A.1
Korsheninnikova, E.2
Seppala-Lindroos, A.3
Vehkavaara, S.4
Goto, T.5
Halavaara, J.6
Hakkinen, A.M.7
Yki-Jarvinen, H.8
-
54
-
-
0035985081
-
Vascular function, insulin resistance and fatty acids
-
COI: 1:CAS:528:DC%2BD38XlsVWkt7o%3D
-
Steinberg HO, Baron AD (2002) Vascular function, insulin resistance and fatty acids. Diabetologia 45:623–634
-
(2002)
Diabetologia
, vol.45
, pp. 623-634
-
-
Steinberg, H.O.1
Baron, A.D.2
-
55
-
-
84879560586
-
Possible mechanisms of local tissue renin-angiotensin system activation in the cardiorenal metabolic syndrome and type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC3MXhtVWrsr3O
-
Hayden MR, Sowers KM, Pulakat L, Joginpally T, Krueger B, Whaley-Connell A, Sowers JR (2011) Possible mechanisms of local tissue renin-angiotensin system activation in the cardiorenal metabolic syndrome and type 2 diabetes mellitus. Cardiorenal Med 1:193–210
-
(2011)
Cardiorenal Med
, vol.1
, pp. 193-210
-
-
Hayden, M.R.1
Sowers, K.M.2
Pulakat, L.3
Joginpally, T.4
Krueger, B.5
Whaley-Connell, A.6
Sowers, J.R.7
-
56
-
-
84867191669
-
Adipose tissue inflammation and ectopic lipid accumulation
-
COI: 1:CAS:528:DC%2BC3sXhslWgsbo%3D
-
Suganami T, Tanaka M, Ogawa Y (2012) Adipose tissue inflammation and ectopic lipid accumulation. Endocr J 59:849–857
-
(2012)
Endocr J
, vol.59
, pp. 849-857
-
-
Suganami, T.1
Tanaka, M.2
Ogawa, Y.3
-
57
-
-
33845866857
-
Inflammation and metabolic disorders
-
COI: 1:CAS:528:DC%2BD28XhtlShtrzK
-
Hotamisligil GS (2006) Inflammation and metabolic disorders. Nature 444:860–867
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
58
-
-
84924750356
-
Gamma-tocotrienol attenuates high-fat diet-induced obesity and insulin resistance by inhibiting adipose inflammation and M1 macrophage recruitment
-
COI: 1:CAS:528:DC%2BC2cXhtlKktr%2FN
-
Zhao L, Kang I, Fang X, Wang W, Lee MA, Hollins RR, Marshall MR, Chung S (2015) Gamma-tocotrienol attenuates high-fat diet-induced obesity and insulin resistance by inhibiting adipose inflammation and M1 macrophage recruitment. Int J Obes (Lond) 39:438–446
-
(2015)
Int J Obes (Lond)
, vol.39
, pp. 438-446
-
-
Zhao, L.1
Kang, I.2
Fang, X.3
Wang, W.4
Lee, M.A.5
Hollins, R.R.6
Marshall, M.R.7
Chung, S.8
-
59
-
-
40449086665
-
Dose translation from animal to human studies revisited
-
COI: 1:CAS:528:DC%2BD1cXjtVaqsrY%3D
-
Reagan-Shaw S, Nihal M, Ahmad N (2008) Dose translation from animal to human studies revisited. FASEB J 22:659–661
-
(2008)
FASEB J
, vol.22
, pp. 659-661
-
-
Reagan-Shaw, S.1
Nihal, M.2
Ahmad, N.3
-
60
-
-
84888130738
-
Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements. Scientific Opinion of the Panel on Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (Question No EFSA Q-2005-146, Q-2005-172, Q-2006-265)
-
EFSA (2008) Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements. Scientific Opinion of the Panel on Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (Question No EFSA Q-2005-146, Q-2005-172, Q-2006-265) EFSA J 604:1–34
-
(2008)
EFSA J
, vol.604
, pp. 1-34
-
-
-
61
-
-
49849083819
-
Induction of characteristic hepatocyte proliferative lesion with dietary exposure of Wistar Hannover rats to tocotrienol for 1 year
-
COI: 1:CAS:528:DC%2BD1cXhtVKmtbrN
-
Tasaki M, Umemura T, Inoue T, Okamura T, Kuroiwa Y, Ishii Y, Maeda M, Hirose M, Nishikawa A (2008) Induction of characteristic hepatocyte proliferative lesion with dietary exposure of Wistar Hannover rats to tocotrienol for 1 year. Toxicology 250:143–150
-
(2008)
Toxicology
, vol.250
, pp. 143-150
-
-
Tasaki, M.1
Umemura, T.2
Inoue, T.3
Okamura, T.4
Kuroiwa, Y.5
Ishii, Y.6
Maeda, M.7
Hirose, M.8
Nishikawa, A.9
-
62
-
-
84873486708
-
Abstract 1299: a phase I dose-escalation study of the safety, PK, and PD of vitamin E delta-tocotrienol administered to subjects with resectable pancreatic exocrine neoplasia
-
Springett GM, Neuger AM, Centeno BA, Hutchinson T, Jump H, Lush R, Sebti S, Malafa MP (2011) Abstract 1299: a phase I dose-escalation study of the safety, PK, and PD of vitamin E delta-tocotrienol administered to subjects with resectable pancreatic exocrine neoplasia. Cancer Res 71:1299
-
(2011)
Cancer Res
, vol.71
, pp. 1299
-
-
Springett, G.M.1
Neuger, A.M.2
Centeno, B.A.3
Hutchinson, T.4
Jump, H.5
Lush, R.6
Sebti, S.7
Malafa, M.P.8
-
63
-
-
33745870857
-
Postprandial levels of the natural vitamin E tocotrienol in human circulation
-
COI: 1:CAS:528:DC%2BD28XlsFOnurw%3D
-
Khosla P, Patel V, Whinter JM, Khanna S, Rakhkovskaya M, Roy S, Sen CK (2006) Postprandial levels of the natural vitamin E tocotrienol in human circulation. Antioxid Redox Signal 8:1059–1068
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1059-1068
-
-
Khosla, P.1
Patel, V.2
Whinter, J.M.3
Khanna, S.4
Rakhkovskaya, M.5
Roy, S.6
Sen, C.K.7
-
64
-
-
33750620058
-
Postprandial metabolic fate of tocotrienol-rich vitamin E differs significantly from that of alpha-tocopherol
-
COI: 1:CAS:528:DC%2BD28XhtFWgtrrF
-
Fairus S, Nor RM, Cheng HM, Sundram K (2006) Postprandial metabolic fate of tocotrienol-rich vitamin E differs significantly from that of alpha-tocopherol. Am J Clin Nutr 84:835–842
-
(2006)
Am J Clin Nutr
, vol.84
, pp. 835-842
-
-
Fairus, S.1
Nor, R.M.2
Cheng, H.M.3
Sundram, K.4
-
65
-
-
84855766685
-
Alpha-tocotrienol is the most abundant tocotrienol isomer circulated in plasma and lipoproteins after postprandial tocotrienol-rich vitamin E supplementation
-
COI: 1:CAS:528:DC%2BC38XktlSktbs%3D
-
Fairus S, Nor RM, Cheng HM, Sundram K (2012) Alpha-tocotrienol is the most abundant tocotrienol isomer circulated in plasma and lipoproteins after postprandial tocotrienol-rich vitamin E supplementation. Nutr J 11:5
-
(2012)
Nutr J
, vol.11
, pp. 5
-
-
Fairus, S.1
Nor, R.M.2
Cheng, H.M.3
Sundram, K.4
-
66
-
-
0037249854
-
Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats
-
COI: 1:CAS:528:DC%2BD3sXhtFKhsLk%3D
-
Yap SP, Yuen KH, Lim AB (2003) Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats. J Pharm Pharmacol 55:53–58
-
(2003)
J Pharm Pharmacol
, vol.55
, pp. 53-58
-
-
Yap, S.P.1
Yuen, K.H.2
Lim, A.B.3
-
67
-
-
0035140716
-
Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status
-
COI: 1:CAS:528:DC%2BD3MXht1ShsrY%3D
-
Yap SP, Yuen KH, Wong JW (2001) Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status. J Pharm Pharmacol 53:67–71
-
(2001)
J Pharm Pharmacol
, vol.53
, pp. 67-71
-
-
Yap, S.P.1
Yuen, K.H.2
Wong, J.W.3
-
68
-
-
84866703336
-
Physiological effects and tissue distribution from large doses of tocotrienol in rats
-
COI: 1:CAS:528:DC%2BC38XhsVKhs7vM
-
Shibata A, Nakagawa K, Shirakawa H, Kobayashi T, Kawakami Y, Takashima R, Ohashi A, Sato S, Ohsaki Y, Kimura F, Kimura T, Tsuduki T, Komai M, Miyazawa T (2012) Physiological effects and tissue distribution from large doses of tocotrienol in rats. Biosci Biotechnol Biochem 76:1805–1808
-
(2012)
Biosci Biotechnol Biochem
, vol.76
, pp. 1805-1808
-
-
Shibata, A.1
Nakagawa, K.2
Shirakawa, H.3
Kobayashi, T.4
Kawakami, Y.5
Takashima, R.6
Ohashi, A.7
Sato, S.8
Ohsaki, Y.9
Kimura, F.10
Kimura, T.11
Tsuduki, T.12
Komai, M.13
Miyazawa, T.14
-
69
-
-
84857049136
-
Tissue distribution of alpha- and gamma-tocotrienol and gamma-tocopherol in rats and interference with their accumulation by alpha-tocopherol
-
COI: 1:CAS:528:DC%2BC38Xht1aqsb0%3D
-
Uchida T, Abe C, Nomura S, Ichikawa T, Ikeda S (2012) Tissue distribution of alpha- and gamma-tocotrienol and gamma-tocopherol in rats and interference with their accumulation by alpha-tocopherol. Lipids 47:129–139
-
(2012)
Lipids
, vol.47
, pp. 129-139
-
-
Uchida, T.1
Abe, C.2
Nomura, S.3
Ichikawa, T.4
Ikeda, S.5
-
70
-
-
0036241711
-
Effect of sesaminol on plasma and tissue alpha-tocopherol and alpha-tocotrienol concentrations in rats fed a vitamin E concentrate rich in tocotrienols
-
COI: 1:CAS:528:DC%2BD38XjsVKnu78%3D
-
Yamashita K, Ikeda S, Iizuka Y, Ikeda I (2002) Effect of sesaminol on plasma and tissue alpha-tocopherol and alpha-tocotrienol concentrations in rats fed a vitamin E concentrate rich in tocotrienols. Lipids 37:351–358
-
(2002)
Lipids
, vol.37
, pp. 351-358
-
-
Yamashita, K.1
Ikeda, S.2
Iizuka, Y.3
Ikeda, I.4
-
71
-
-
83855162889
-
Do tocotrienols have potential as neuroprotective dietary factors?
-
COI: 1:CAS:528:DC%2BC3MXhs1CqsL3I
-
Frank J, Chin XW, Schrader C, Eckert GP, Rimbach G (2012) Do tocotrienols have potential as neuroprotective dietary factors? Ageing Res Rev 11:163–180
-
(2012)
Ageing Res Rev
, vol.11
, pp. 163-180
-
-
Frank, J.1
Chin, X.W.2
Schrader, C.3
Eckert, G.P.4
Rimbach, G.5
-
72
-
-
0001032512
-
A new salt mixture for use in experimental diets
-
COI: 1:CAS:528:DyaA2sXlslaguw%3D%3D
-
Hubbell RB, Mendel LB, Wakeman AJ (1937) A new salt mixture for use in experimental diets. J Nutr 14:273–285
-
(1937)
J Nutr
, vol.14
, pp. 273-285
-
-
Hubbell, R.B.1
Mendel, L.B.2
Wakeman, A.J.3
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