Tissue distribution of α- And γ-tocotrienol and γ-tocopherol in rats and interference with their accumulation by α-tocopherol

Lipids

Volumn 47, Issue 2, 2012, Pages 129-139

  Uchida, Tomono ^a   Abe, Chisato ^b   Nomura, Saki ^a   Ichikawa, Tomio ^a   Ikeda, Saiko ^a  

^a NAGOYA UNIVERSITY OF ARTS AND SCIENCES   (Japan)

^b Tsu City College   (Japan)

Author keywords

Adipose tissue; Distribution; Rat; Tocopherol; Tocotrienol; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL TRANSFER PROTEIN; ALPHA TOCOTRIENOL; CARRIER PROTEIN; GAMMA TOCOPHEROL; GAMMA TOCOTRIENOL; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BIODEGRADATION; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; MALE; NONHUMAN; NUTRITIONAL ASSESSMENT; NUTRITIONAL REQUIREMENT; RAT; TISSUE DISTRIBUTION; VITAMIN BLOOD LEVEL; VITAMIN INTAKE; VITAMIN METABOLISM; VITAMIN SUPPLEMENTATION;

ALPHA-TOCOPHEROL; ANIMALS; ANTIOXIDANTS; CARRIER PROTEINS; CHROMANS; GAMMA-TOCOPHEROL; MALE; RATS; RATS, WISTAR; TISSUE DISTRIBUTION; VITAMIN E;

RATTUS;

EID: 84857049136     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-011-3620-7     Document Type: Article

References (39)

1. Schaffer S, Müller WE, Eckert GP (2005) Tocotrienols: constitutional effects in aging and disease. J Nutr 135: 151-154 (Pubitemid 40194470)
2. Serbinova EA, Packer L (1994) Antioxidant properties of α-tocopherol and α-tocotrienol. Methods Enzymol 234: 354-366
3. Miyazawa T, Shibata A, Sookwong P, Kawakami Y, Eitsuka T, Asai A, Oikawa S, Nakagawa K (2009) Antiangiogenic and anticancer potential of unsaturated vitamin E (tocotrienol). J Nutr Biochem 20: 79-86
4. Nesaretnam K (2008) Multitargeted therapy of cancer by tocotrienols. Cancer Lett 269: 388-395
5. Qureshi AA, Salser WA, Parmar R, Emeson EE (2001) Novel tocotrienols of rice bran inhibit atherosclerotic lesions in C57BL/6 ApoE-deficient mice. J Nutr 131: 2606-2618 (Pubitemid 32947784)
6. Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ (1993) Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl- coenzyme A reductase. J Biol Chem 268: 11230-11238 (Pubitemid 23162316)
7. Khanna S, Parinandi NL, Kotha SR, Roy S, Rink C, Bibus D, Sen CK (2010) Nanomolar vitamin E α-tocotrienol inhibits glutamateinduced activation of phospholipase A2 and causes neuroprotection. J Neurochem 112: 1249-1260
8. Sen CK, Khanna S, Roy S (2004) Tocotrienol: the natural vitamin E to defend the nervous system? Ann NY Acad Sci 1031: 127-142 (Pubitemid 40361749)
9. Kayden HJ, Traber MG (1993) Absorption, lipoprotein transport, and regulation of plasma concentrations of vitamin E in humans. J Lipid Res 34: 343-358 (Pubitemid 23095362)
10. Traber MG, Sies H (1996) Vitamin E in humans: demand and delivery. Annu Rev Nutr 16: 321-347 (Pubitemid 26286857)
11. Abe C, Ikeda S, Uchida T, Yamashita K, Ichikawa T (2007) Triton WR1339, an inhibitor of lipoprotein lipase, decreases vitamin E concentration in some tissues of rats by inhibiting its transport to liver. J Nutr 137: 345-350 (Pubitemid 46213447)
12. Traber MG, Arai H (1999) Molecular mechanisms of vitamin E transport. Annu Rev Nutr 19: 343-355 (Pubitemid 29380608)
13. Traber MG, Burton GW, Hamilton RL (2004) Vitamin E trafficking. Ann NY Acad Sci 1031: 1-12 (Pubitemid 40361738)
14. Hosomi A, Arita M, Sato Y, Kiyose C, Ueda T, Igarashi O, Arai H, Inoue K (1997) Affinity for a-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. FEBS Lett 409: 105-108 (Pubitemid 27248576)
15. Ikeda S, Toyoshima K, Yamashita K (2001) Dietary sesame seeds elevate α-and γ-tocotrienol concentrations in skin and adipose tissue of rats fed the tocotrienol-rich fraction extracted from palm oil. J Nutr 131: 2892-2897 (Pubitemid 33069372)
16. Hayes KC, Pronczuk A, Liang JS (1993) Differences in the plasma transport and tissue concentrations of tocopherols and tocotrienols: observations in humans and hamsters. Proc Soc Exp Biol Med 202: 353-359 (Pubitemid 23073473)
17. Podda M, Weber C, Traber MG, Packer L (1996) Simultaneous determination of tissue tocopherols, tocotrienols, ubiquinols, and ubiquinones. J Lipid Res 37: 893-901 (Pubitemid 26140825)
18. Ikeda S, Niwa T, Yamashita K (2000) Selective uptake of dietary tocotrienols into rat skin. J Nutr Sci Vitaminol 46: 141-143 (Pubitemid 30457178)
19. Ikeda S, Tohyama T, Yoshimura H, Hamamura K, Abe K, Yamashita K (2003) Dietary α-tocopherol decrease α-tocotrienol but not γ-tocotrienol concentration in rats. J Nutr 133: 428-434 (Pubitemid 36172895)
20. American Institute of Nutrition (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123: 1939-1951
21. Machlin LJ, Keating J, Nelson J, Brin M, Filipski R, Miller ON (1979) Availability of adipose tissue tocopherol in the guinea pig. J Nutr 109: 105-109 (Pubitemid 9161375)
22. Azhar S, Cao L, Reaven E (1995) Alteration of the adrenal antioxidant defense system during aging in rats. J Clin Invest 96: 1414-1424
23. Abidi P, Leers-Sucheta S, Azhar S (2004) Suppression of steroidogenesis and activator protein-1 transcription factor activity in rat adrenals by vitamin E deficiency-induced chronic oxidative stress. J Nutr Biochem 15: 210-219 (Pubitemid 38447259)
24. Goti D, Hrzenjak A, Levak-Frank S, Frank S, van der Westhuyzen DR, Malle E, Sattler W (2001) Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E. J Neurochem 76: 498-508 (Pubitemid 32097027)
25. Balazs Z, Panzenboeck U, Hammer A, Sovic A, Quehenberger O, Malle E, Sattler W (2004) Uptake and transport of high-density lipoprotein (HDL) and HDL-associated a-tocopherol by an in vitro blood-brain barrier model. J Neurochem 89: 939-950 (Pubitemid 38684741)
26. Kolleck I, Schlame M, Fechner H, Looman AC, Wissel H, Rüstow B (1999) HDL is the major source of vitamin E for type II pneumocytes. Free Radic Biol Med 27: 882-890 (Pubitemid 29454592)
27. Reboul E, Klein A, Bietrix F, Gleize B, Malezet-Desmoulins C, Schneider M, Margotat A, Lagrost L, Collet X, Borel P (2006) Scavenger receptor class B type I (SR-BI) is involved in vitamin E transport across the enterocyte. J Biol Chem 281: 4739-4745 (Pubitemid 43847734)
28. Mardones P, Strobel P, Miranda S, Leighton F, Quiñnoes V, Amigo L, Rozowski J, Krieger M, Rigotti A (2002) α-Tocopherol metabolism is abnormal in scavenger receptor class B type I (SRBI)- deficient mice. J Nutr 132: 443-449 (Pubitemid 34208747)
29. Landschulz KT, Pathak RK, Rigotti A, Krieger M, Hobbs HH (1996) Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat. J Clin Invest 98: 984-995 (Pubitemid 26293317)
30. Schultz M, Leist M, Petrzika M, Gassmann B, Brigelius-Flohé R (1995) Novel urinary metabolite of α-tocopherol, 2,5,7,8-tetramethyl- 2(20-carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply? Am J Clin Nutr 62: 1527S- 1534S
31. Swanson JE, Ben RN, Burton GW, Parker RS (1999) Urinary excretion of 2,7,8-trimethyl-2-(β-carboxyethyl)-6-hydroxychroman is a major route of elimination of γ-tocopherol in humans. J Lipid Res 40: 665-671 (Pubitemid 29173769)
32. Lodge JK, Ridlington J, Leonard S, Vaule H, Traber MG (2001) α-and γ-Tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine. Lipids 36: 43-48 (Pubitemid 32163621)
33. Birringer M, Pfluger P, Kluth D, Landes N, Brigelius-Flohé R (2002) Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cells. J Nutr 132: 3113-3118
34. Sontag TJ, Parker RS (2002) Cytochrome P450 ω-hydroxylase pathway of tocopherol catabolism: novel mechanism of regulation of vitamin E status. J Biol Chem 277: 25290-25296 (Pubitemid 34951838)
35. Sontag TJ, Parker RS (2007) Influence of major structural features of tocopherols and tocotrienols on their ω-oxidation by tocopherol-ω- hydroxylase. J Lipid Res 48: 1090-1098 (Pubitemid 46708676)
36. Uchida T, Nomura S, Ichikawa T, Abe C, Ikeda S (2011) Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol. J Nutr Sci Vitaminol 57: 326-332
37. Leonard SW, Paterson E, Atkinson JK, Ramakrishnan R, Cross CE, Traber MG (2005) Studies in humans using deuteriumlabeled α-and γ-tocopherols demonstrate faster plasma c-tocopherol disappearance and greater γ-metabolite production. Free Radic Biol Med 38: 857-866 (Pubitemid 40321077)
38. Abe C, Uchida T, Ohta M, Ichikawa T, Yamashita K, Ikeda S (2007) Cytochrome P450-dependent metabolism of vitamin E isoforms is a critical determinant of their tissue concentrations in rats. Lipids 42: 637-645 (Pubitemid 47196032)
39. Kiyose C, Saito H, Kaneko K, Hamamura K, Tomioka M, Ueda T, Igarashi O (2001) α-Tocopherol affects the urinary and biliary excretion of 2, 7, 8-trimethyl-2(20-carboxyethyl)-6-hydroxychroman, γ-tocopherol metabolite, in rats. Lipids 36: 467-472 (Pubitemid 32550047)